R Cools

Summary

Publications

  1. pmc Striatal dopamine predicts outcome-specific reversal learning and its sensitivity to dopaminergic drug administration
    Roshan Cools
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    J Neurosci 29:1538-43. 2009
  2. doi request reprint Top-down attentional control in Parkinson's disease: salient considerations
    Roshan Cools
    Donders Institute for Brain, Cognition, and Behavior, Radboud University Nijmegen Medical Centre, The Netherlands
    J Cogn Neurosci 22:848-59. 2010
  3. pmc Enhanced frontal function in Parkinson's disease
    R Cools
    Donders Institute for Brain, Cognition and Behaviour, Centre for Cognitive Neuroimaging, Radboud University Nijmegen Medical Centre, Department of Psychiatry, The Netherlands
    Brain 133:225-33. 2010
  4. ncbi request reprint Dopaminergic modulation of cognitive control: distinct roles for the prefrontal cortex and the basal ganglia
    Martine van Schouwenburg
    Donders Institute for Brain, Cognition and Behaviour, Centre for Cognitive Neuroimaging, University Nijmegen, Kapittelweg 29, 6500 HB, Nijmegen, The Netherlands
    Curr Pharm Des 16:2026-32. 2010
  5. pmc Striatal dopamine mediates the interface between motivational and cognitive control in humans: evidence from genetic imaging
    Esther Aarts
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    Neuropsychopharmacology 35:1943-51. 2010
  6. doi request reprint The human basal ganglia modulate frontal-posterior connectivity during attention shifting
    Martine R van Schouwenburg
    Radboud University Nijmegen, Donders Institute for Brain, Cognition, and Behaviour, Centre for Cognitive Neuroimaging, 6500 HB, Nijmegen, The Netherlands
    J Neurosci 30:9910-8. 2010
  7. ncbi request reprint Serotoninergic regulation of emotional and behavioural control processes
    Roshan Cools
    F C Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Trends Cogn Sci 12:31-40. 2008

Detail Information

Publications7

  1. pmc Striatal dopamine predicts outcome-specific reversal learning and its sensitivity to dopaminergic drug administration
    Roshan Cools
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    J Neurosci 29:1538-43. 2009
    ..These data demonstrate that the effects of D(2) receptor stimulation on reversal learning in humans depend on task demands and baseline striatal dopamine synthesis capacity...
  2. doi request reprint Top-down attentional control in Parkinson's disease: salient considerations
    Roshan Cools
    Donders Institute for Brain, Cognition, and Behavior, Radboud University Nijmegen Medical Centre, The Netherlands
    J Cogn Neurosci 22:848-59. 2010
    ..The results provide a striking reinterpretation of prior set-shifting data and provide the first direct evidence for a failure of top-down attentional control, resembling that seen after catecholamine depletion in the pFC...
  3. pmc Enhanced frontal function in Parkinson's disease
    R Cools
    Donders Institute for Brain, Cognition and Behaviour, Centre for Cognitive Neuroimaging, Radboud University Nijmegen Medical Centre, Department of Psychiatry, The Netherlands
    Brain 133:225-33. 2010
    ..Dopaminergic medication may reinstate distractibility by normalizing the balance between striatal and prefrontal dopamine transmission...
  4. ncbi request reprint Dopaminergic modulation of cognitive control: distinct roles for the prefrontal cortex and the basal ganglia
    Martine van Schouwenburg
    Donders Institute for Brain, Cognition and Behaviour, Centre for Cognitive Neuroimaging, University Nijmegen, Kapittelweg 29, 6500 HB, Nijmegen, The Netherlands
    Curr Pharm Des 16:2026-32. 2010
    ....
  5. pmc Striatal dopamine mediates the interface between motivational and cognitive control in humans: evidence from genetic imaging
    Esther Aarts
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    Neuropsychopharmacology 35:1943-51. 2010
    ..These data establish a crucial role for human striatal dopamine in the modulation of cognitive flexibility by reward anticipation, thus, elucidating the neurochemical mechanism of the interaction between motivation and cognitive control...
  6. doi request reprint The human basal ganglia modulate frontal-posterior connectivity during attention shifting
    Martine R van Schouwenburg
    Radboud University Nijmegen, Donders Institute for Brain, Cognition, and Behaviour, Centre for Cognitive Neuroimaging, 6500 HB, Nijmegen, The Netherlands
    J Neurosci 30:9910-8. 2010
    ..These data integrate disparate literatures on top-down control by the prefrontal cortex and selective gating by the basal ganglia and highlight the importance of the basal ganglia for high-level cognitive control...
  7. ncbi request reprint Serotoninergic regulation of emotional and behavioural control processes
    Roshan Cools
    F C Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Trends Cogn Sci 12:31-40. 2008
    ..We review evidence from studies with human volunteers and experimental animals that begins to elucidate the neurobiological systems underlying these different effects...