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An open-label study of the efficacy and tolerability of microencapsulated hydroquinone 4% and retinol 0.15% with antioxidants for the treatment of hyperpigmentationFran E Cook-Bolden
Department of Dermatology, Columbia University College of Physicians and Surgeons, New York, New York, USA
Cutis 81:365-71. 2008..Reflectance spectrophotometer readings also were performed at each study visit and demonstrated a significant reduction in melanin content as early as week 4 (target A, P < or = .001; target B, P = .002)...
