Research Topics
| P KiehlSummaryAffiliation: Comenius University Publications
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Detail Information
Publications
Accuracy of frozen section measurements for the determination of Breslow tumour thickness in primary malignant melanomaP Kiehl
Department of Dermatology and Allergology, Hannover Medical University, Germany
Histopathology 34:257-61. 1999..To look for significant differences of BTT due to freezing or paraffin embedding, we evaluated a larger series of melanocytic lesions as far as possible excluding other technical influences...
Quantification of eosinophilic granule protein deposition in biopsies of inflammatory skin diseases by automated image analysis of highly sensitive immunostainingP Kiehl
Department of Dermatology and Allergology, Hannover Medical University, Germany
Anal Cell Pathol 19:153-62. 1999..The method may be valuable for the cell-independent segmentation of immunostaining in other applications as well...
DNA image cytometry in malignant and benign sweat gland tumoursM Vogelbruch
Department of Dermatology and Allergology, Hannover Medical University, Ricklinger Strasse 5, D 30449 Hannover, Germany
Br J Dermatol 142:688-93. 2000..These results suggest that the detection of DNA aneuploidy in sweat gland tumours using ICM-DNA is a clear and specific indicator of prospective malignancy...
Specificity of tyrosinase and HMB45 PCR in the detection of melanoma metastases in sentinel lymph node biopsiesR Gutzmer
Department of Dermatology and Allergology, Hannover Medical University, Ricklinger Strasse 5, D 30449 Hannover, Germany
Histopathology 41:510-8. 2002..The aim of this study was to determine the specificity of polymerase chain reaction (PCR) techniques for the evaluation of lymph nodes with regard to melanoma metastases in comparison with histology and immunohistology...
11q23 allelic loss is associated with regional lymph node metastasis in melanomaR A Herbst
Department of Dermatology and Allergology, Hannover Medical University, Germany
Clin Cancer Res 6:3222-7. 2000..These findings support our conclusion and give additional evidence for the hypothesis of molecular heterogeneity of early tumor cell populations in melanoma...
Allelic loss at the neurofibromatosis type 1 (NF1) gene locus is frequent in desmoplastic neurotropic melanomaR Gutzmer
Department of Dermatology and Allergology, Hannover Medical University, Germany
Hum Genet 107:357-61. 2000..DNM may represent an interesting tumour model tor the further elucidation of the cellular functions and tumour-suppressive potential of neurofibromin...
Tissue eosinophilia in acute and chronic atopic dermatitis: a morphometric approach using quantitative image analysis of immunostainingP Kiehl
Department of Dermatology and Allergology, Hannover Medical University, Ricklinger Str 5, D 30449 Hannover, Germany
Br J Dermatol 145:720-9. 2001..The frequency and amount of tissue eosinophilia in spontaneous lesions of acute and chronic atopic dermatitis (AD) are still a matter of controversy, and little is known about the distribution of eosinophilia in skin...
Detection of clonal T cell receptor gamma gene rearrangements in cutaneous T cell lymphoma by LightCycler-polymerase chain reactionR Gutzmer
Department of Dermatology and Allergology, Hannover Medical University, Hannover, Germany
J Invest Dermatol 116:926-32. 2001....
Successful treatment of anogenital Bowen's disease with the immunomodulator imiquimod, and monitoring of therapy by DNA image cytometryR Gutzmer
Department of Dermatology and Allergology, Hannover Medical University, Ricklinger Str 5, Germany
Br J Dermatol 147:160-5. 2002..Therefore, imiquimod might be a treatment option for Bowen's disease, particularly in patients where other treatment modalities such as surgery are contraindicated...
Differentiation between malignant and benign follicular adnexal tumours of the skin by DNA image cytometryM Vogelbruch
Department of Dermatology and Allergology, Hannover Medical University, Ricklinger Str 5, D 30449 Hannover, Germany
Br J Dermatol 146:238-43. 2002..However, little is known about DNA ICM in cutaneous adnexal tumours with follicular differentiation...
Characterization of the CC chemokine receptor 3 on human keratinocytesH Petering
Hannover Medical University, Department of Dermatology and Allergology, Hannover, Germany
J Invest Dermatol 116:549-55. 2001..Therefore, the identification of CC chemokine receptor 3 on epidermal keratinocytes may indicate a role for CC chemokine receptor 3 and its ligands in skin physiology and pathophysiology...
