Gonzalo J Diaz

Summary

Affiliation: Universidad Nacional de Colombia
Country: Colombia

Publications

  1. doi request reprint Aflatoxicosis in chickens (Gallus gallus): an example of hormesis?
    G J Diaz
    Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, D C, Colombia
    Poult Sci 87:727-32. 2008
  2. doi request reprint Method validation for the determination of ochratoxin A in green and soluble coffee by immunoaffinity column cleanup and liquid chromatography
    G J Diaz
    Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, D C, Colombia
    Mycotoxin Res 20:59-67. 2004
  3. doi request reprint First colombian interlaboratory study for the determination of aflatoxin B1 in yellow corn
    G J Diaz
    Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Colombia
    Mycotoxin Res 20:11-8. 2004
  4. ncbi request reprint Stability of aflatoxins in solution
    Gonzalo J Diaz
    Universidad Nacional de Colombia, Facultad de Medicina Veterinaria y de Zootecnia, Laboratorio de Toxicologia, Bogota, DC, Colombia
    J AOAC Int 95:1084-8. 2012
  5. doi request reprint The role of selected cytochrome P450 enzymes on the bioactivation of aflatoxin B1 by duck liver microsomes
    Gonzalo J Diaz
    Universidad Nacional de Colombia, Bogota, DC, Colombia
    Avian Pathol 39:279-85. 2010
  6. ncbi request reprint Occurrence of aflatoxin M1 in retail milk samples from Bogotá, Colombia
    G J Diaz
    Laboratorio de Toxicologia, Departamento de Ciencias para la Salud Animal, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, Colombia
    Food Addit Contam 23:811-5. 2006
  7. doi request reprint Cytochrome P450 enzymes involved in the metabolism of aflatoxin B1 in chickens and quail
    G J Diaz
    Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, D C Colombia
    Poult Sci 89:2461-9. 2010
  8. doi request reprint Bioactivation of aflatoxin B1 by turkey liver microsomes: responsible cytochrome P450 enzymes
    G J Diaz
    Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, D C Colombia
    Br Poult Sci 51:828-37. 2010
  9. doi request reprint Evaluation of the ability of a feed additive to ameliorate the adverse effects of aflatoxins in turkey poults
    G J Diaz
    Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, Colombia
    Br Poult Sci 50:240-50. 2009
  10. ncbi request reprint Microsomal and cytosolic biotransformation of aflatoxin B1 in four poultry species
    M C Lozano
    Departamento de Farmacia, Universidad Nacional de Colombia, Bogota, Colombia
    Br Poult Sci 47:734-41. 2006

Collaborators

Detail Information

Publications16

  1. doi request reprint Aflatoxicosis in chickens (Gallus gallus): an example of hormesis?
    G J Diaz
    Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, D C, Colombia
    Poult Sci 87:727-32. 2008
    ..The implications of such hormetic dose responses are briefly discussed...
  2. doi request reprint Method validation for the determination of ochratoxin A in green and soluble coffee by immunoaffinity column cleanup and liquid chromatography
    G J Diaz
    Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, D C, Colombia
    Mycotoxin Res 20:59-67. 2004
    ..4 to 13.9 μg/kg. Six of the 42 green coffee samples analysed (14.3%) contained OTA at levels ranging from 0.9 to 19.4 μg/kg. The validated method can be used to monitor OTA levels in Colombian coffee for export or for local consumption...
  3. doi request reprint First colombian interlaboratory study for the determination of aflatoxin B1 in yellow corn
    G J Diaz
    Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Colombia
    Mycotoxin Res 20:11-8. 2004
    ..These results indicate that an improvement in quality assurance is needed in Colombian laboratories. The routine use of reference standards and reference materials is highly recommended...
  4. ncbi request reprint Stability of aflatoxins in solution
    Gonzalo J Diaz
    Universidad Nacional de Colombia, Facultad de Medicina Veterinaria y de Zootecnia, Laboratorio de Toxicologia, Bogota, DC, Colombia
    J AOAC Int 95:1084-8. 2012
    ....
  5. doi request reprint The role of selected cytochrome P450 enzymes on the bioactivation of aflatoxin B1 by duck liver microsomes
    Gonzalo J Diaz
    Universidad Nacional de Colombia, Bogota, DC, Colombia
    Avian Pathol 39:279-85. 2010
    ..Further studies are needed to fully elucidate the phase I hepatic metabolism of AFB1 in ducks, the only poultry species that develops hepatic cancer from AFB1 exposure...
  6. ncbi request reprint Occurrence of aflatoxin M1 in retail milk samples from Bogotá, Colombia
    G J Diaz
    Laboratorio de Toxicologia, Departamento de Ciencias para la Salud Animal, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, Colombia
    Food Addit Contam 23:811-5. 2006
    ....
  7. doi request reprint Cytochrome P450 enzymes involved in the metabolism of aflatoxin B1 in chickens and quail
    G J Diaz
    Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, D C Colombia
    Poult Sci 89:2461-9. 2010
    ..The results of the present study indicate that CYP2A6 and, to a lesser extent, CYP1A1 are responsible for the bioactivation of AFB(1) into AFBO in both quail and chicken hepatic microsomes...
  8. doi request reprint Bioactivation of aflatoxin B1 by turkey liver microsomes: responsible cytochrome P450 enzymes
    G J Diaz
    Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, D C Colombia
    Br Poult Sci 51:828-37. 2010
    ..5. This is the first study reporting the role of CYP2A6 in the bioactivation of AFB1 in an avian species and the role of CYP1A1 in any species...
  9. doi request reprint Evaluation of the ability of a feed additive to ameliorate the adverse effects of aflatoxins in turkey poults
    G J Diaz
    Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, Colombia
    Br Poult Sci 50:240-50. 2009
    ....
  10. ncbi request reprint Microsomal and cytosolic biotransformation of aflatoxin B1 in four poultry species
    M C Lozano
    Departamento de Farmacia, Universidad Nacional de Colombia, Bogota, Colombia
    Br Poult Sci 47:734-41. 2006
    ..8. Because AFBO production by microsomes in ducks was relatively low, it is possible that other toxicity mechanisms are involved in this highly susceptible species...
  11. pmc Basolateral and canalicular transport of xenobiotics in the hepatocyte: A review
    G J Diaz
    Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Apartado Aéreo 76948, Santafe de Bogota, D C, Colombia
    Cytotechnology 34:225-35. 2000
    ..The concludingremarks point out areas of research that need to be addressedin order to answer important questions that still remainunanswered in this important field of study...
  12. ncbi request reprint Phase II in vitro metabolism of 3-methylindole metabolites in porcine liver
    G J Diaz
    Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Apartado Aéreo 76948, Bogota, D C, Colombia
    Xenobiotica 33:485-98. 2003
    ..5. Sulphation of 5-OH-3MI was high in pigs with low levels of 3MI in fat. No relationship was observed between 3MI levels in fat and either glutathione transferase or glucuronidation activities in liver...
  13. ncbi request reprint Evaluation of the efficacy of a feed additive to ameliorate the toxic effects of 4,15-diacetoxiscirpenol in growing chicks
    G J Diaz
    Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, DC
    Poult Sci 81:1492-5. 2002
    ..More studies are required to determine if a higher dose of Mycofix could be capable of counteracting the adverse effects of 2 ppm dietary DAS on chicken performance...
  14. ncbi request reprint Intoxication of Crotalaria pallida seeds to growing broiler chicks
    G J Diaz
    Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota DC, Colombia
    Vet Hum Toxicol 45:187-9. 2003
    ..No differences in ALT, AST or GGT were observed at day 21. Dietary levels equal to or greater than 1% CP are toxic for growing broiler chicks...
  15. ncbi request reprint Individual and combined effects of aflatoxin and gizzerosine in broiler chickens
    G J Diaz
    Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia
    Br Poult Sci 36:729-36. 1995
    ..5. The combination 3 mg/kg AFB1/4 mg/kg GIZZ was more toxic than the same concentrations of single toxins and may pose a greater economic threat to the poultry producer than either toxin individually...
  16. ncbi request reprint Determination of ochratoxin A in green coffee by immunoaffinity column cleanup and liquid chomatography: collaborative study
    Eugenia Azevedo Vargas
    Ministerio da Agricultura, Pecuária e Abastecimento, Laboratório de Controle de Qualidade e Segurança Alimentar, Av Raja Gabaglia, 245, Cidade Jardim, Belo Horizonte, MG, CEP 30380 090, Brazil
    J AOAC Int 88:773-9. 2005
    ..85, at the studied range, for spiked and naturally contaminated materials. The mean recovery was 92.8% for green coffee material spiked with OTA at a level of 4.82 ng/g...