Research Topics
| Gonzalo J DiazSummaryAffiliation: Universidad Nacional de Colombia Country: Colombia Publications
| Collaborators
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Detail Information
Publications
Aflatoxicosis in chickens (Gallus gallus): an example of hormesis?G J Diaz
Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, D C, Colombia
Poult Sci 87:727-32. 2008..The implications of such hormetic dose responses are briefly discussed...- Method validation for the determination of ochratoxin A in green and soluble coffee by immunoaffinity column cleanup and liquid chromatographyG J Diaz
Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, D C, Colombia
Mycotoxin Res 20:59-67. 2004..4 to 13.9 μg/kg. Six of the 42 green coffee samples analysed (14.3%) contained OTA at levels ranging from 0.9 to 19.4 μg/kg. The validated method can be used to monitor OTA levels in Colombian coffee for export or for local consumption... - First colombian interlaboratory study for the determination of aflatoxin B1 in yellow cornG J Diaz
Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Colombia
Mycotoxin Res 20:11-8. 2004..These results indicate that an improvement in quality assurance is needed in Colombian laboratories. The routine use of reference standards and reference materials is highly recommended... 
Stability of aflatoxins in solutionGonzalo J Diaz
Universidad Nacional de Colombia, Facultad de Medicina Veterinaria y de Zootecnia, Laboratorio de Toxicologia, Bogota, DC, Colombia
J AOAC Int 95:1084-8. 2012....- The role of selected cytochrome P450 enzymes on the bioactivation of aflatoxin B1 by duck liver microsomesGonzalo J Diaz
Universidad Nacional de Colombia, Bogota, DC, Colombia
Avian Pathol 39:279-85. 2010..Further studies are needed to fully elucidate the phase I hepatic metabolism of AFB1 in ducks, the only poultry species that develops hepatic cancer from AFB1 exposure... - Occurrence of aflatoxin M1 in retail milk samples from Bogotá, ColombiaG J Diaz
Laboratorio de Toxicologia, Departamento de Ciencias para la Salud Animal, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, Colombia
Food Addit Contam 23:811-5. 2006.... - Cytochrome P450 enzymes involved in the metabolism of aflatoxin B1 in chickens and quailG J Diaz
Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, D C Colombia
Poult Sci 89:2461-9. 2010..The results of the present study indicate that CYP2A6 and, to a lesser extent, CYP1A1 are responsible for the bioactivation of AFB(1) into AFBO in both quail and chicken hepatic microsomes... - Bioactivation of aflatoxin B1 by turkey liver microsomes: responsible cytochrome P450 enzymesG J Diaz
Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, D C Colombia
Br Poult Sci 51:828-37. 2010..5. This is the first study reporting the role of CYP2A6 in the bioactivation of AFB1 in an avian species and the role of CYP1A1 in any species... - Evaluation of the ability of a feed additive to ameliorate the adverse effects of aflatoxins in turkey poultsG J Diaz
Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, Colombia
Br Poult Sci 50:240-50. 2009.... - Microsomal and cytosolic biotransformation of aflatoxin B1 in four poultry speciesM C Lozano
Departamento de Farmacia, Universidad Nacional de Colombia, Bogot, Colombia
Br Poult Sci 47:734-41. 2006..8. Because AFBO production by microsomes in ducks was relatively low, it is possible that other toxicity mechanisms are involved in this highly susceptible species... 
Basolateral and canalicular transport of xenobiotics in the hepatocyte: A reviewG J Diaz
Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Apartado Aéreo 76948, Santafe de Bogota, D C, Colombia
Cytotechnology 34:225-35. 2000..The concludingremarks point out areas of research that need to be addressedin order to answer important questions that still remainunanswered in this important field of study...- Phase II in vitro metabolism of 3-methylindole metabolites in porcine liverG J Diaz
Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Apartado Aéreo 76948, Bogota, D C, Colombia
Xenobiotica 33:485-98. 2003..5. Sulphation of 5-OH-3MI was high in pigs with low levels of 3MI in fat. No relationship was observed between 3MI levels in fat and either glutathione transferase or glucuronidation activities in liver... - Evaluation of the efficacy of a feed additive to ameliorate the toxic effects of 4,15-diacetoxiscirpenol in growing chicksG J Diaz
Laboratorio de Toxicologia, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogota, DC
Poult Sci 81:1492-5. 2002..More studies are required to determine if a higher dose of Mycofix could be capable of counteracting the adverse effects of 2 ppm dietary DAS on chicken performance... - Intoxication of Crotalaria pallida seeds to growing broiler chicksG J Diaz
, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, , Colombia
Vet Hum Toxicol 45:187-9. 2003..No differences in ALT, AST or GGT were observed at day 21. Dietary levels equal to or greater than 1% CP are toxic for growing broiler chicks... - Individual and combined effects of aflatoxin and gizzerosine in broiler chickensG J Diaz
Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia
Br Poult Sci 36:729-36. 1995..5. The combination 3 mg/kg AFB1/4 mg/kg GIZZ was more toxic than the same concentrations of single toxins and may pose a greater economic threat to the poultry producer than either toxin individually... - Determination of ochratoxin A in green coffee by immunoaffinity column cleanup and liquid chomatography: collaborative studyEugenia Azevedo Vargas
Ministerio da Agricultura, Pecuária e Abastecimento, Laboratório de Controle de Qualidade e Segurança Alimentar, Av Raja Gabaglia, 245, Cidade Jardim, Belo Horizonte, MG, CEP 30380 090, Brazil
J AOAC Int 88:773-9. 2005..85, at the studied range, for spiked and naturally contaminated materials. The mean recovery was 92.8% for green coffee material spiked with OTA at a level of 4.82 ng/g...