Nancy Gore Saravia

Summary

Country: Colombia

Publications

  1. pmc Plumbing the brain drain
    Nancy Gore Saravia
    Centro Internacional de Entrenamiento e Investigaciones Medicas, CIDEIM, Cali, Colombia
    Bull World Health Organ 82:608-15. 2004
  2. ncbi request reprint Protective immunogenicity of the paraflagellar rod protein 2 of Leishmania mexicana
    N G Saravia
    Centro Internacional de Entrenamiento e Investigaciones Medicas, Apartado Aéreo 5390, Cali, Colombia
    Vaccine 23:984-95. 2005
  3. ncbi request reprint Pathogenicity and protective immunogenicity of cysteine proteinase-deficient mutants of Leishmania mexicana in non-murine models
    Nancy Gore Saravia
    Centro Internacional de Entrenamiento e Investigaciones Medicas CIDEIM, Apartado Aéreo 5390, Cali, Colombia
    Vaccine 24:4247-59. 2006
  4. pmc Novel approach to in vitro drug susceptibility assessment of clinical strains of Leishmania spp
    Olga Fernández
    Centro Internacional de Entrenamiento e Investigaciones Médica, Cali, Colombia
    J Clin Microbiol 50:2207-11. 2012
  5. doi request reprint T-bet, GATA-3, and Foxp3 expression and Th1/Th2 cytokine production in the clinical outcome of human infection with Leishmania (Viannia) species
    Yira Rosalba Diaz
    Centro Internacional de Entrenamiento e Investigaciones Medicas CIDEIM, Cali, Colombia
    J Infect Dis 202:406-15. 2010
  6. ncbi request reprint Evidence for leishmania (viannia) parasites in the skin and blood of patients before and after treatment
    Carolina Vergel
    Centro Internacional de Entrenamiento e Investigaciones Medicas, Cali, Valle, Colombia
    J Infect Dis 194:503-11. 2006
  7. pmc Miltefosine and antimonial drug susceptibility of Leishmania Viannia species and populations in regions of high transmission in Colombia
    Olga Lucía Fernández
    Centro Internacional de Entrenamiento e Investigaciones Medicas CIDEIM, Cali, Colombia
    PLoS Negl Trop Dis 8:e2871. 2014
  8. pmc Regulatory T cells in the pathogenesis and healing of chronic human dermal leishmaniasis caused by Leishmania (Viannia) species
    Daniel Rodriguez-Pinto
    Centro Internacional de Entrenamiento e Investigaciones Medicas CIDEIM, Cali, Colombia
    PLoS Negl Trop Dis 6:e1627. 2012
  9. doi request reprint Detection of Leishmania in unaffected mucosal tissues of patients with cutaneous leishmaniasis caused by Leishmania (Viannia) species
    Roger Adrian Figueroa
    Centro Internacional de Entrenamiento e Investigaciones Medicas, Cali, Colombia
    J Infect Dis 200:638-46. 2009
  10. ncbi request reprint Heterogeneity, geographic distribution, and pathogenicity of serodemes of Leishmania viannia in Colombia
    Nancy Gore Saravia
    Centro Internacional de Entrenamiento e Investigaciones Medicas, Cali, Colombia
    Am J Trop Med Hyg 66:738-44. 2002

Collaborators

  • Diane McMahon-Pratt
  • Daniel Garcerant
  • John Walker
  • B L Travi
  • Liliana Valderrama
  • Maria Adelaida Gomez
  • Daniel Rodriguez-Pinto
  • Yira Rosalba Diaz
  • Olga Lucía Fernández
  • Clemencia Ovalle
  • Víctor Manuel Blanco
  • Adriana Navas
  • Victor M Blanco
  • Yira Diaz-Toro
  • Olga Fernández
  • Carolina Gallego
  • Roger Adrian Figueroa
  • Mauricio Perez
  • Carolina Vergel
  • Nora Guarin
  • Hector Hernán Henao
  • Sandra Muvdi
  • Roni Koren
  • Laura Jimena Rojas
  • Isabel Rodriguez
  • Deninson Alejandro Vargas
  • Dan Zilberstein
  • Ricardo Marquez
  • Alexandra Cossio
  • Javier D Martinez
  • Adriana Cruz
  • Lady Ramírez
  • Mabel Valderrama
  • Noah Craft
  • Harry Castillo
  • Douglas Golenbock
  • Ricardo Rojas
  • Leyder Elena Lozano
  • Jair Alexander Tellez
  • Ibeth Cristina Romero
  • Martin Prager
  • Maria Teresa Cardona
  • Robinson Pacheco
  • Rafael Tovar
  • Gloria I Palma
  • Claudia Jimena Posso
  • Horacio Cadena
  • Ricardo Palacios
  • Claude Pirmez
  • Arlen Gómez
  • Yaneth Osorio

Detail Information

Publications17

  1. pmc Plumbing the brain drain
    Nancy Gore Saravia
    Centro Internacional de Entrenamiento e Investigaciones Medicas, CIDEIM, Cali, Colombia
    Bull World Health Organ 82:608-15. 2004
    ..As a result, only a small proportion of the most highly educated individuals migrate from these countries, and research and development opportunities employ national talent and even attract immigrants...
  2. ncbi request reprint Protective immunogenicity of the paraflagellar rod protein 2 of Leishmania mexicana
    N G Saravia
    Centro Internacional de Entrenamiento e Investigaciones Medicas, Apartado Aéreo 5390, Cali, Colombia
    Vaccine 23:984-95. 2005
    ..mexicana promastigotes, supporting the relevance of PFR-2 as a potential vaccine constituent...
  3. ncbi request reprint Pathogenicity and protective immunogenicity of cysteine proteinase-deficient mutants of Leishmania mexicana in non-murine models
    Nancy Gore Saravia
    Centro Internacional de Entrenamiento e Investigaciones Medicas CIDEIM, Apartado Aéreo 5390, Cali, Colombia
    Vaccine 24:4247-59. 2006
    ..These findings support the feasibility of using genetically attenuated live Leishmania to achieve protective immunity...
  4. pmc Novel approach to in vitro drug susceptibility assessment of clinical strains of Leishmania spp
    Olga Fernández
    Centro Internacional de Entrenamiento e Investigaciones Médica, Cali, Colombia
    J Clin Microbiol 50:2207-11. 2012
    ....
  5. doi request reprint T-bet, GATA-3, and Foxp3 expression and Th1/Th2 cytokine production in the clinical outcome of human infection with Leishmania (Viannia) species
    Yira Rosalba Diaz
    Centro Internacional de Entrenamiento e Investigaciones Medicas CIDEIM, Cali, Colombia
    J Infect Dis 202:406-15. 2010
    ..T cell differentiation determines susceptibility and resistance to experimental cutaneous leishmaniasis, yet mixed T1/Th2 responses characterize the clinical spectrum of human infection with Leishmania (Viannia) species...
  6. ncbi request reprint Evidence for leishmania (viannia) parasites in the skin and blood of patients before and after treatment
    Carolina Vergel
    Centro Internacional de Entrenamiento e Investigaciones Medicas, Cali, Valle, Colombia
    J Infect Dis 194:503-11. 2006
    ..However, the "domestication" of transmission and the increase in treatment failure with antimonial drugs have raised the suspicion of anthroponotic transmission of American cutaneous leishmaniasis...
  7. pmc Miltefosine and antimonial drug susceptibility of Leishmania Viannia species and populations in regions of high transmission in Colombia
    Olga Lucía Fernández
    Centro Internacional de Entrenamiento e Investigaciones Medicas CIDEIM, Cali, Colombia
    PLoS Negl Trop Dis 8:e2871. 2014
    ..Miltefosine is administered as second line treatment since 2005. The susceptibility of circulating populations of Leishmania to these drugs is unknown despite clinical evidence supporting the emergence of resistance...
  8. pmc Regulatory T cells in the pathogenesis and healing of chronic human dermal leishmaniasis caused by Leishmania (Viannia) species
    Daniel Rodriguez-Pinto
    Centro Internacional de Entrenamiento e Investigaciones Medicas CIDEIM, Cali, Colombia
    PLoS Negl Trop Dis 6:e1627. 2012
    ..The inflammatory response is prominent in the pathogenesis of dermal leishmaniasis. We hypothesized that regulatory T cells (Tregs) may be diminished in chronic dermal leishmaniasis (CDL) and contribute to healing during treatment...
  9. doi request reprint Detection of Leishmania in unaffected mucosal tissues of patients with cutaneous leishmaniasis caused by Leishmania (Viannia) species
    Roger Adrian Figueroa
    Centro Internacional de Entrenamiento e Investigaciones Medicas, Cali, Colombia
    J Infect Dis 200:638-46. 2009
    ..The natural history and pathogenesis of mucosal disease are enigmatic. Parasitological evaluation of mucosal tissues has been constrained by the invasiveness of conventional sampling methods...
  10. ncbi request reprint Heterogeneity, geographic distribution, and pathogenicity of serodemes of Leishmania viannia in Colombia
    Nancy Gore Saravia
    Centro Internacional de Entrenamiento e Investigaciones Medicas, Cali, Colombia
    Am J Trop Med Hyg 66:738-44. 2002
    ..panamensis strains. Null strains of L. braziliensis and L. panamensis were more frequently isolated from mucosal leishmaniasis than strains that expressed species specific epitopes, suggesting that these strains may be more pathogenic...
  11. pmc Leishmania panamensis infection and antimonial drugs modulate expression of macrophage drug transporters and metabolizing enzymes: impact on intracellular parasite survival
    Maria Adelaida Gomez
    Centro Internacional de Entrenamiento e Investigaciones Medicas CIDEIM, Carrera 125 No 19 225 Cali, Colombia
    J Antimicrob Chemother 69:139-49. 2014
    ....
  12. pmc CD4 T cell activation by B cells in human Leishmania (Viannia) infection
    Daniel Rodriguez-Pinto
    Centro Internacional de Entrenamiento e Investigaciones Medicas CIDEIM, Cali, Colombia
    BMC Infect Dis 14:108. 2014
    ..An effective adaptive immune response requires activation of specific CD4 T cells. The capacity of B cells to activate CD4 T cells in human cutaneous leishmaniasis caused by Leishmania (Viannia) has not been evaluated...
  13. ncbi request reprint Comparative immunohistological analysis of the Montenegro skin test reaction in asymptomatic infection and in acute and chronic cutaneous leishmaniasis
    Nora Guarin
    Centro Internacional de Entrenamiento e Investigaciones Medicas, Cali, Colombia
    Biomedica 26:38-48. 2006
    ..The Montenegro skin test reaction and leishmaniasis lesions share fundamental characteristics of a delayed type hypersensitivity reaction...
  14. pmc Toll-like receptors participate in macrophage activation and intracellular control of Leishmania (Viannia) panamensis
    Carolina Gallego
    Centro Internacional de Entrenamiento e Investigaciones Medicas, Cali, Colombia
    Infect Immun 79:2871-9. 2011
    ..Together, these findings support the participation of TLR4 and endosomal TLRs in the activation of host macrophages by L. panamensis and in the early control of infection...
  15. ncbi request reprint [Efficacy and toxicity of pentavalent antimonials (Glucantime and Pentostam) in an American cutaneous leishmaniasis animal model: luminometry application]
    Hector Hernán Henao
    Centro Internacional de Entrenamiento e Investigaciones Medicas, CIDEIM, Cali, Colombia
    Biomedica 24:393-402. 2004
    ..These effects were absent in the animals treated with Glucantime. The results confirmed clinical observations regarding the similar efficacy of the two drugs, as well as the higher local toxicity of Pentostam...
  16. pmc Clinical and epidemiologic profile of cutaneous leishmaniasis in Colombian children: considerations for local treatment
    Victor M Blanco
    Centro Internacional de Entrenamiento e Investigaciones Medicas CIDEIM International Center for Medical Research and Training, Cali, Colombia
    Am J Trop Med Hyg 89:359-64. 2013
    ..Recommended local treatments for New World CL have potential but limited applicability in children. Individual risk-benefit assessment and effectiveness data in children may increase eligibility...
  17. ncbi request reprint [Leishmaniasis: a public health challenge that demands concerted effort and will (editorial)]
    Nancy Gore Saravia
    Biomedica 26:7-9. 2006