Juana Angel

Summary

Affiliation: Pontificia Universidad Javeriana
Country: Colombia

Publications

  1. ncbi request reprint Rotavirus vaccines: recent developments and future considerations
    Juana Angel
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Carrera 7, 40 62, Bogota, Colombia
    Nat Rev Microbiol 5:529-39. 2007
  2. pmc Rotavirus immune responses and correlates of protection
    Juana Angel
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Bogota, Colombia
    Curr Opin Virol 2:419-25. 2012
  3. ncbi request reprint Rotavirus-specific B cells induced by recent infection in adults and children predominantly express the intestinal homing receptor alpha4beta7
    Ana Maria Gonzalez
    Instituto de Genetica Humana Pontificia Universidad Javeriana, Bogota, Colombia
    Virology 305:93-105. 2003
  4. ncbi request reprint Human rotavirus specific T cells: quantification by ELISPOT and expression of homing receptors on CD4+ T cells
    Olga Lucía Rojas
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Bogota, Colombia
    Virology 314:671-9. 2003
  5. pmc Characterization of rotavirus specific B cells and their relation with serological memory
    Olga Lucía Rojas
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Carrera 7 40 62, Bogota, Colombia
    Virology 380:234-42. 2008
  6. pmc Human rotavirus-specific IgM Memory B cells have differential cloning efficiencies and switch capacities and play a role in antiviral immunity in vivo
    Carlos F Narvaez
    Instituto de Genetica Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogota, Colombia
    J Virol 86:10829-40. 2012
  7. doi request reprint Human myeloid dendritic cells treated with supernatants of rotavirus infected Caco-2 cells induce a poor Th1 response
    Luz Stella Rodríguez
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Bogota, Colombia
    Cell Immunol 272:154-61. 2012
  8. doi request reprint A TGF-beta mediated regulatory mechanism modulates the T cell immune response to rotavirus in adults but not in children
    Martha C Mesa
    Instituto de Genetica Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Carrera 7 No 40 62, Edificio 32, Bogota, Colombia
    Virology 399:77-86. 2010
  9. ncbi request reprint Evaluation of circulating intestinally committed memory B cells in children vaccinated with attenuated human rotavirus vaccine
    Olga Lucía Rojas
    Instituto de Genetica Humana, Colombia
    Viral Immunol 20:300-11. 2007
  10. doi request reprint Membrane vesicles released by intestinal epithelial cells infected with rotavirus inhibit T-cell function
    Alfonso Barreto
    Instituto de Genetica Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogota, Colombia
    Viral Immunol 23:595-608. 2010

Collaborators

  • HARRY BERNARD GREENBERG
  • Pierre Pothier
  • Eugene Butcher
  • Marie Wolf
  • Irene Perez-Schael
  • E J Kunkel
  • Manuel A Franco
  • Luz Stella Rodríguez
  • Olga Lucía Rojas
  • Carlos F Narvaez
  • Martha C Mesa
  • Olga L Rojas
  • Daniel Herrera
  • Maria C Jaimes
  • Alfonso Barreto
  • Ana Maria Gonzalez
  • Miguel Parra
  • Carolina Duarte-Rey
  • Carlos Fernando Narváez
  • Isabela Cajiao
  • Evelyne Kohli
  • J Mauricio Calvo-Calle
  • Manuel Franco
  • Lawrence J Stern
  • Ruben D Mantilla
  • Carlos A Parra-López
  • Camilo Vásquez
  • Adrish Sen
  • Ningguo Feng
  • Lina Gutiérrez
  • Juan Manuel Lozano
  • Javier Castañeda
  • Ricardo Pinzón
  • Carolina Guzmán
  • Beatrice De Vos
  • Yohanna Andrade
  • Liliana Uribe
  • Liliana Caicedo
  • Dulce Soler
  • Dorsey Bass
  • Nicole H Lazarus
  • Rosabel González
  • Jean Cohen
  • Annie Charpilienne

Detail Information

Publications18

  1. ncbi request reprint Rotavirus vaccines: recent developments and future considerations
    Juana Angel
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Carrera 7, 40 62, Bogota, Colombia
    Nat Rev Microbiol 5:529-39. 2007
    ....
  2. pmc Rotavirus immune responses and correlates of protection
    Juana Angel
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Bogota, Colombia
    Curr Opin Virol 2:419-25. 2012
    ..Protection against rotavirus following vaccination is substantially heterotypic; nonetheless, a role for homotypic immunity in selection of circulating postvaccination strains needs further study...
  3. ncbi request reprint Rotavirus-specific B cells induced by recent infection in adults and children predominantly express the intestinal homing receptor alpha4beta7
    Ana Maria Gonzalez
    Instituto de Genetica Humana Pontificia Universidad Javeriana, Bogota, Colombia
    Virology 305:93-105. 2003
    ....
  4. ncbi request reprint Human rotavirus specific T cells: quantification by ELISPOT and expression of homing receptors on CD4+ T cells
    Olga Lucía Rojas
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Bogota, Colombia
    Virology 314:671-9. 2003
    ....
  5. pmc Characterization of rotavirus specific B cells and their relation with serological memory
    Olga Lucía Rojas
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Carrera 7 40 62, Bogota, Colombia
    Virology 380:234-42. 2008
    ..Our studies contribute to understand the relationship between circulating mBc and serological memory, and enhance our capacity to develop better correlates of protection against RV disease...
  6. pmc Human rotavirus-specific IgM Memory B cells have differential cloning efficiencies and switch capacities and play a role in antiviral immunity in vivo
    Carlos F Narvaez
    Instituto de Genetica Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogota, Colombia
    J Virol 86:10829-40. 2012
    ..Thus, RV-IgM(+) mBc are heterogeneous, occur more frequently than estimated by traditional limiting dilution analysis, have the capacity to switch Ig class in vitro as well as in vivo, and can mediate systemic antiviral immunity...
  7. doi request reprint Human myeloid dendritic cells treated with supernatants of rotavirus infected Caco-2 cells induce a poor Th1 response
    Luz Stella Rodríguez
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Bogota, Colombia
    Cell Immunol 272:154-61. 2012
    ..The results suggest that the TGF-β1 induced by rotavirus could be an immune evasion mechanism, and may partially explain the poor rotavirus-specific T cell response we have previously evidenced...
  8. doi request reprint A TGF-beta mediated regulatory mechanism modulates the T cell immune response to rotavirus in adults but not in children
    Martha C Mesa
    Instituto de Genetica Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Carrera 7 No 40 62, Edificio 32, Bogota, Colombia
    Virology 399:77-86. 2010
    ..The ALK5i effect was observed in adults but not in children with RV-GE, who had normal numbers of TGF-beta+ Treg cells. Thus, a TGF-beta-mediated regulatory mechanism that modulates RV-T cells in adults is not evident in children...
  9. ncbi request reprint Evaluation of circulating intestinally committed memory B cells in children vaccinated with attenuated human rotavirus vaccine
    Olga Lucía Rojas
    Instituto de Genetica Humana, Colombia
    Viral Immunol 20:300-11. 2007
    ..However, the correlation coefficients for both tests were low (<0.2), suggesting that other factors are important in explaining protection from disease...
  10. doi request reprint Membrane vesicles released by intestinal epithelial cells infected with rotavirus inhibit T-cell function
    Alfonso Barreto
    Instituto de Genetica Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogota, Colombia
    Viral Immunol 23:595-608. 2010
    ..24 g/mL). Both types of MV from RV-infected cells were more efficient at inhibiting T-cell function than were those from non-infected cells. We propose that RV infection of IEC releases MV that modulate viral immunity...
  11. pmc Interaction of rotavirus with human myeloid dendritic cells
    Carlos F Narvaez
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Carrera 7 40 62, Bogota, Colombia
    J Virol 79:14526-35. 2005
    ..Finally, IDC treated with RV strongly stimulated naive allogeneic CD4+ T cells to secrete Th1 cytokines. Thus, although RV does not seem to be a strong maturing stimulus for DC, it promotes their capacity to prime Th1 cells...
  12. pmc Circulating human rotavirus specific CD4 T cells identified with a class II tetramer express the intestinal homing receptors α4β7 and CCR9
    Miguel Parra
    Instituto de Genetica Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogota, Colombia
    Virology 452:191-201. 2014
    ..Circulating RV-specific CD4 T cells represent a unique subset that expresses intestinal homing receptors...
  13. pmc Simultaneous assessment of rotavirus-specific memory B cells and serological memory after B cell depletion therapy with rituximab
    Daniel Herrera
    Instituto de Genetica Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogota, Colombia
    PLoS ONE 9:e97087. 2014
    ....
  14. doi request reprint Immunomodulators released during rotavirus infection of polarized caco-2 cells
    Luz Stella Rodríguez
    Instituto de Genetica Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogota, Colombia
    Viral Immunol 22:163-72. 2009
    ..This set of immunomodulators is known to induce a non-inflammatory (non-Th-1) immune response, and may be determining, in part, the relatively low T-cell immune response observed in blood samples after RV infection...
  15. ncbi request reprint Interaction of rotavirus with human peripheral blood mononuclear cells: plasmacytoid dendritic cells play a role in stimulating memory rotavirus specific T cells in vitro
    Martha C Mesa
    Instituto de Genetica Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Carrera 7 No 40 62, Edificio 32, Bogota, Colombia
    Virology 366:174-84. 2007
    ..Thus, although PBMC are susceptible to the initial steps of RV infection, most PBMC of children with RV-gastroenteritis are not infected...
  16. ncbi request reprint Immunity and correlates of protection for rotavirus vaccines
    Manuel A Franco
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Bogota, Colombia
    Vaccine 24:2718-31. 2006
    ....
  17. pmc Frequencies of virus-specific CD4(+) and CD8(+) T lymphocytes secreting gamma interferon after acute natural rotavirus infection in children and adults
    Maria C Jaimes
    Instituto de Genetica Humana, Pontificia Universidad Javeriana, Bogota, Colombia
    J Virol 76:4741-9. 2002
    ..In both adults and children, the frequencies of CD4(+) cells secreting gamma interferon in response to SEB were higher than the frequencies of cells secreting IL-13...
  18. pmc Maturation and trafficking markers on rotavirus-specific B cells during acute infection and convalescence in children
    Maria C Jaimes
    V A Palo Alto Health Care System, 3801 Miranda Ave, MC154C, Palo Alto, CA 94304, USA
    J Virol 78:10967-76. 2004
    ..Interestingly, RV memory cells generally lack CCR9 and CCR10 and instead express CCR6, which may enable recruitment to diverse epithelial sites of inflammation...