Juan Manuel Anaya

Summary

Country: Colombia

Publications

  1. pmc Is there a common genetic basis for autoimmune diseases?
    Juan Manuel Anaya
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Clin Dev Immunol 13:185-95. 2006
  2. pmc Genetic basis of Sjögren's syndrome. How strong is the evidence?
    Juan Manuel Anaya
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Medllín, Colombia
    Clin Dev Immunol 13:209-22. 2006
  3. ncbi Immunogenetics of primary Sjögren's syndrome in Colombians
    Juan Manuel Anaya
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Semin Arthritis Rheum 34:735-43. 2005
  4. ncbi The kaleidoscope of autoimmunity: multiple autoimmune syndromes and familial autoimmunity
    Juan Manuel Anaya
    Professor of Medicine and Chief, Cellular Biology and Immunogenetics Unit, , Cra 72 A No 78 B 141, , Colombia and Universidad del Rosario, , Colombia
    Expert Rev Clin Immunol 3:623-35. 2007
  5. ncbi Severe rheumatoid valvular heart disease
    Juan Manuel Anaya
    Unidad de Biología Celular e Inmunogenética, Corporacion para Investigaciones Biologicas, Universidad del Rosario, Cra 72 A No 78 B 141, Medellin, Colombia
    Clin Rheumatol 25:743-5. 2006
  6. ncbi Multiple autoimmune disease in a patient with hyperprolactinemia
    Juan Manuel Anaya
    Cellular and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Universidad del Rosario, Medellin, Colombia
    Isr Med Assoc J 7:740-1. 2005
  7. ncbi Clinical and immunological factors associated with lupus nephritis in patients from northwestern Colombia
    Juan Manuel Anaya
    Clínica Universitaria Bolivariana, Facultad de Medicina, Universidad Pontificia Bolivariana, Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Biomedica 23:293-300. 2003
  8. ncbi Autoimmune disease aggregation in families with primary Sjögren's syndrome
    Juan Manuel Anaya
    Cellular Biology and Immunogenetics Unit, CIB Universitario del Rosario, Medellin, Colombia, South America
    J Rheumatol 33:2227-34. 2006
  9. ncbi D6S439 microsatellite identifies a new susceptibility region for primary Sjögren's syndrome
    Juan Manuel Anaya
    Cellular Biology and Immunogenetic Unit, Corporacion para Investigaciones Biologicas CIB, Cra 72 A No 78 B 141, Medellin, Colombia
    J Rheumatol 30:2152-6. 2003
  10. ncbi Familial clustering of autoimmune diseases in patients with type 1 diabetes mellitus
    Juan Manuel Anaya
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Cra 72 A No 78 B 141, Medellin, Colombia
    J Autoimmun 26:208-14. 2006

Collaborators

Detail Information

Publications68

  1. pmc Is there a common genetic basis for autoimmune diseases?
    Juan Manuel Anaya
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Clin Dev Immunol 13:185-95. 2006
    ..Both autoimmunity family history and the co-occurrence of ADs in affected probands should be considered when performing genetic association and linkage studies...
  2. pmc Genetic basis of Sjögren's syndrome. How strong is the evidence?
    Juan Manuel Anaya
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Medllín, Colombia
    Clin Dev Immunol 13:209-22. 2006
    ..Since there is no strong evidence for a specific genetic component in SS, a large international and collaborative study would be suitable to assess the genetics of this disorder...
  3. ncbi Immunogenetics of primary Sjögren's syndrome in Colombians
    Juan Manuel Anaya
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Semin Arthritis Rheum 34:735-43. 2005
    ..A research project centered on primary SS in Colombians was initiated in January 1996 to better define these characteristics...
  4. ncbi The kaleidoscope of autoimmunity: multiple autoimmune syndromes and familial autoimmunity
    Juan Manuel Anaya
    Professor of Medicine and Chief, Cellular Biology and Immunogenetics Unit, , Cra 72 A No 78 B 141, , Colombia and Universidad del Rosario, , Colombia
    Expert Rev Clin Immunol 3:623-35. 2007
    ..Herein, both the multiple autoimmune syndromes and familial autoimmunity are discussed and various epidemiological factors considered in the context of the common genetic background of autoimmunity...
  5. ncbi Severe rheumatoid valvular heart disease
    Juan Manuel Anaya
    Unidad de Biología Celular e Inmunogenética, Corporacion para Investigaciones Biologicas, Universidad del Rosario, Cra 72 A No 78 B 141, Medellin, Colombia
    Clin Rheumatol 25:743-5. 2006
    ..Herein, two cases of RA-related endocarditis, one of which required valve replacement, are described. Etanercept was useful in controlling the articular and extra-articular RA compromise in both cases...
  6. ncbi Multiple autoimmune disease in a patient with hyperprolactinemia
    Juan Manuel Anaya
    Cellular and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Universidad del Rosario, Medellin, Colombia
    Isr Med Assoc J 7:740-1. 2005
  7. ncbi Clinical and immunological factors associated with lupus nephritis in patients from northwestern Colombia
    Juan Manuel Anaya
    Clínica Universitaria Bolivariana, Facultad de Medicina, Universidad Pontificia Bolivariana, Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Biomedica 23:293-300. 2003
    ..Lupus nephritis is a major risk factor leading to repeated hospitalizations. This study may help to assist in public health policies in our population in order to improve patient outcomes while simultaneously reducing disease costs...
  8. ncbi Autoimmune disease aggregation in families with primary Sjögren's syndrome
    Juan Manuel Anaya
    Cellular Biology and Immunogenetics Unit, CIB Universitario del Rosario, Medellin, Colombia, South America
    J Rheumatol 33:2227-34. 2006
    ..We examined the aggregation of autoimmune diseases among first-degree relatives (FDR) of patients with primary Sjögren's syndrome (pSS)...
  9. ncbi D6S439 microsatellite identifies a new susceptibility region for primary Sjögren's syndrome
    Juan Manuel Anaya
    Cellular Biology and Immunogenetic Unit, Corporacion para Investigaciones Biologicas CIB, Cra 72 A No 78 B 141, Medellin, Colombia
    J Rheumatol 30:2152-6. 2003
    ....
  10. ncbi Familial clustering of autoimmune diseases in patients with type 1 diabetes mellitus
    Juan Manuel Anaya
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Cra 72 A No 78 B 141, Medellin, Colombia
    J Autoimmun 26:208-14. 2006
    ....
  11. ncbi Meta-analysis of HLA-DRB1 and HLA-DQB1 polymorphisms in Latin American patients with systemic lupus erythematosus
    Natalia Castano-Rodriguez
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Autoimmun Rev 7:322-30. 2008
    ..To estimate the common effect size of HLA-DRB1 and -DQB1 alleles on systemic lupus erythematosus (SLE) susceptibility across Latin America populations through a meta-analysis...
  12. ncbi TAP, HLA-DQB1, and HLA-DRB1 polymorphism in Colombian patients with primary Sjögren's syndrome
    Juan Manuel Anaya
    Rheumatology Unit, Corporacion para Investigaciones Biologicas CIB, Medellin, Colombia
    Semin Arthritis Rheum 31:396-405. 2002
    ..Thus, we investigated the influence of transporters associated with antigen processing (TAP), human leukocyte antigen (HLA)-DQB1, and HLA-DRB1 gene polymorphism in mestizo Colombian patients with pSS...
  13. doi Gender differences in Latin-American patients with rheumatoid arthritis
    Carolina Barragán-Martínez
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia
    Gend Med 9:490-510.e5. 2012
    ..Data on the effect of gender in rheumatoid arthritis (RA) in non-Caucasian populations is scarce. Latin America and the Caribbean (LAC) is a large population with unique characteristics, including high admixture...
  14. ncbi Autoimmunity and tuberculosis. Opposite association with TNF polymorphism
    Paula A Correa
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas CIB, Medellin, Colombia
    J Rheumatol 32:219-24. 2005
    ....
  15. ncbi HLA class II polymorphism in Latin American patients with multiple sclerosis
    Olga Lucía Rojas
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia
    Autoimmun Rev 9:407-13. 2010
    ....
  16. ncbi Th1/Th2 cytokines in patients with systemic lupus erythematosus: is tumor necrosis factor alpha protective?
    Diana Gómez
    Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Semin Arthritis Rheum 33:404-13. 2004
    ..To determine the circulating levels of Th1 and Th2 cytokines in patients with systemic lupus erythematosus (SLE) and to elucidate their association with disease activity and autoimmune response...
  17. ncbi TIRAP (MAL) S180L polymorphism is a common protective factor against developing tuberculosis and systemic lupus erythematosus
    John Castiblanco
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas CIB, Medellin, Colombia
    Infect Genet Evol 8:541-4. 2008
    ....
  18. doi Risk factors associated with different stages of atherosclerosis in Colombian patients with rheumatoid arthritis
    Adriana Rojas-Villarraga
    Cellular Biology and Immunogenetics Unit CBIGU, Corporacion para Investigaciones Biologicas CIB, Medellin, Colombia
    Semin Arthritis Rheum 38:71-82. 2008
    ....
  19. doi Cardiovascular disease is associated with extra-articular manifestations in patients with rheumatoid arthritis
    Oscar Danilo Ortega-Hernandez
    Center for Autoimmune Diseases Research CREA, School of Medicine, Rosario University, Carrera 24 63 C 69, Corporacion para Investigaciones Biologicas, Bogota, Colombia
    Clin Rheumatol 28:767-75. 2009
    ....
  20. ncbi The IkappaBL gene polymorphism influences risk of acquiring systemic lupus erythematosus and Sjögren's syndrome
    John Castiblanco
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Hum Immunol 69:45-51. 2008
    ..Our findings indicate that the IkappaBL gene influences the risk of developing SLE and pSS...
  21. ncbi Meta-analysis of HLA-DRB1 polymorphism in Latin American patients with rheumatoid arthritis
    Angelica M Delgado-Vega
    Unidad de Biología Celular e Inmunogenética, Corporacion para Investigaciones Biologicas, Medellin, Colombia School of Medicine, Universidad del Rosario, Bogota, Colombia
    Autoimmun Rev 6:402-8. 2007
    ..To estimate the common effect size of HLA-DRB1 alleles on rheumatoid arthritis (RA) susceptibility across Latin America populations through a meta-analysis combining the results of published data...
  22. doi Novel risk factors for cardiovascular disease in rheumatoid arthritis
    Jenny Amaya-Amaya
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Carrera 24 No 63C 69, Bogota, Colombia
    Immunol Res 56:267-86. 2013
    ..Our results may assist health professionals and policymakers in making decisions about CVD in patients with RA...
  23. doi The multiple autoimmune syndromes. A clue for the autoimmune tautology
    Juan Manuel Anaya
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Carrera 24 63C 69, Piso 3, Bogota, Colombia
    Clin Rev Allergy Immunol 43:256-64. 2012
    ..The MAS represent the best example of polyautoimmunity as well as the effect of a single genotype on diverse phenotypes. Its study provides important clues to elucidate the common mechanisms of ADs (i.e., autoimmune tautology)...
  24. doi HLA and Sjögren's syndrome susceptibility. A meta-analysis of worldwide studies
    Paola Cruz-Tapias
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia
    Autoimmun Rev 11:281-7. 2012
    ....
  25. doi Lupus nephritis in Colombians: contrasts and comparisons with other populations
    Juan Manuel Anaya
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Carrera 24 63 C 69, Bogota, Colombia
    Clin Rev Allergy Immunol 40:199-207. 2011
    ..The identified clinical- and laboratory-associated factors would assist earlier diagnosis and guide decisions on therapeutic interventions on this critical and frequent complication of SLE...
  26. doi HLA-Class II in Latin American patients with type 1 diabetes
    Adriana Rojas-Villarraga
    Center for Autoimmune Diseases Research, Universidad del Rosario, Bogota, Colombia
    Autoimmun Rev 9:666-73. 2010
    ..To identify and estimate the common effect size of HLA-Class II contributing to susceptibility on T1D in Latin America (LA) through a meta-analysis...
  27. ncbi Interleukin 10 (IL-10) influences autoimmune response in primary Sjögren's syndrome and is linked to IL-10 gene polymorphism
    Juan Manuel Anaya
    Corporacion para Investigaciones Biologicas, Clínica Universitaria Bolivariana, School of Medicine, Universidad Pontificia Bolivariana, Medellin, Colombia
    J Rheumatol 29:1874-6. 2002
    ....
  28. ncbi Sjögren's syndrome at the crossroad of polyautoimmunity
    Manuel J Amador-Patarroyo
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Carrera 24 63 C 69, Bogota, Colombia
    J Autoimmun 39:199-205. 2012
    ..These results may serve to define plausible approaches to study the common mechanisms of autoimmune diseases...
  29. pmc Evaluation of genetic association between an ITGAM non-synonymous SNP (rs1143679) and multiple autoimmune diseases
    Juan Manuel Anaya
    Center for Autoimmune Diseases Research CREA, Universidad del Rosario, Bogota, Colombia
    Autoimmun Rev 11:276-80. 2012
    ..Thus ITGAM may not be a general autoimmunity gene but this variant may be specifically associated with SLE and systemic sclerosis...
  30. doi Human leukocyte antigen class II and type 1 diabetes in Latin America: a combined meta-analysis of association and family-based studies
    Ricardo A Cifuentes
    Center for Autoimmune Diseases Research, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia
    Hum Immunol 72:581-6. 2011
    ..A DRB1*04 risk hierarchy was confirmed with the DRB1*0405 being in the top. A binding prediction analysis disclosed possible receptor-ligand interactions in the HLA-antigenic peptide complex...
  31. ncbi Serious liver disease induced by infliximab
    Gabriel J Tobon
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Clin Rheumatol 26:578-81. 2007
    ..These cases should alert rheumatologists to the possibility of new adverse reactions (liver injury) associated with the use of TNFalpha blockers in an autoimmune setting...
  32. ncbi Common mechanisms of autoimmune diseases (the autoimmune tautology)
    Juan Manuel Anaya
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia
    Autoimmun Rev 11:781-4. 2012
    ..The autoimmune phenotypes vary depending on the target cell and the affected organ, gender, ancestry, trigger factors and age at onset. Ten shared characteristics supporting this logical theory are herein reviewed...
  33. pmc Autoimmune thyroid disease in rheumatoid arthritis: a global perspective
    Jorge Cárdenas Roldán
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia
    Arthritis 2012:864907. 2012
    ..These results may help to further study the common mechanisms of autoimmune diseases, to improve patients' outcome, and to define public health policies. An international consensus to accurately diagnose AITD is warranted...
  34. ncbi A polymorphism in the inducible nitric oxide synthase gene is associated with tuberculosis
    Luis Miguel Gómez
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas CIB, Cra 72 A, No 78 B 141, Medellin, Colombia
    Tuberculosis (Edinb) 87:288-94. 2007
    ..86). No individual association with NOS2A TAAA was detected. These results indicate that a polymorphism in the NOS2A gene influences the susceptibility to TB and suggest a role for NOS2A in the pathogenesis of mycobacterial infection...
  35. ncbi Tuberculosis in patients treated with tumor necrosis factor-alpha antagonists living in an endemic area. Is the risk worthwhile?
    Adriana Rojas-Villarraga
    Clínica Universitaria Bolivariana, Universidad Pontificia Bolivariana, Medellin, Colombia
    Biomedica 27:159-71. 2007
    ..A review of the relevant literature and recommendations are presented as guides for surveillance and prophylaxis on a country-wide basis...
  36. pmc The impact of rheumatoid foot on disability in Colombian patients with rheumatoid arthritis
    Adriana Rojas-Villarraga
    Center for Autoimmune Diseases Research CREA, Corporacion para Investigaciones Biologicas, Universidad del Rosario, Medellin, Colombia
    BMC Musculoskelet Disord 10:67. 2009
    ..The purpose of this research was to evaluate the impact that foot impairment has on the patients' global quality of life (QOL) based on validated scales and its relationship to disease activity...
  37. pmc What is next after the genes for autoimmunity?
    John Castiblanco
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Carrera 24 63 C 69, Bogota, Colombia
    BMC Med 11:197. 2013
    ..Herein, some pitfalls and challenges of the genetics of autoimmune diseases are reviewed, and an approximation to the future of research in this field is presented. ..
  38. pmc How do autoimmune diseases cluster in families? A systematic review and meta-analysis
    Jorge Cárdenas-Roldán
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Carrera 24 63 C 69, Bogota, Colombia
    BMC Med 11:73. 2013
    ..However, aggregation of diverse autoimmune diseases, also known as familial autoimmunity, has been overlooked. Therefore, a systematic review and meta-analysis were performed aimed at gathering evidence about this topic...
  39. ncbi [Anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: relation with clinical features, cytokines and HLA-DRB1]
    Paula A Correa
    Unidad de Biología Celular e Inmunogenética, Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Biomedica 24:140-52. 2004
    ..Antibody synthesis is HLA-DRB1 independent and not correlated with Th1/Th2 cytokines...
  40. ncbi [Genetic epidemiology of rheumatoid arthritis: what to expect from Latin America?]
    Angélica María Delgado-Vega
    Unidad de Biología Celular e Inmunogenética, Corporacion para Investigaciones Biologicas CIB, Universidad del Rosario, Medellin, Colombia
    Biomedica 26:562-84. 2006
    ..The genetic epidemiology of rheumatoid arthritis is herein reviewed; a set of recommendations is provided for the design, analysis and interpretation of genetic association studies in the context of Latin-American populations...
  41. doi Autoimmune diseases in the intensive care unit. An update
    Olga L Quintero
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia
    Autoimmun Rev 12:380-95. 2013
    ..In conclusion, ADs should always be considered in patients with life threatening conditions that warrant critical care. Variables influencing mortality should be promptly identified in order to improve the patients' outcomes...
  42. pmc Organic solvents as risk factor for autoimmune diseases: a systematic review and meta-analysis
    Carolina Barragán-Martínez
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia
    PLoS ONE 7:e51506. 2012
    ..Since controversy exists over whether ADs are caused by OSs, a systematic review and meta-analysis were performed to assess the association between OSs and ADs...
  43. pmc Usefulness of patients-reported outcomes in rheumatoid arthritis focus group
    Jenny Amaya-Amaya
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia
    Arthritis 2012:935187. 2012
    ..02 + 0.037 × RAPID4 + 0.042× patient SJC. Conclusion. PROs applied in focus groups interview are a useful tool for managing patients with RA regardless of gender, educational level, and duration of disease...
  44. pmc Shared HLA Class II in Six Autoimmune Diseases in Latin America: A Meta-Analysis
    Paola Cruz-Tapias
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Carrera 24 No 63C 69, Bogota, Colombia
    Autoimmune Dis 2012:569728. 2012
    ..These results indicate that in Latin Americans ADs share major loci and immune characteristics...
  45. ncbi The nature and nurture of common autoimmunity
    John Castiblanco
    Cellular Biology and Immunogenetics Unit, Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Ann N Y Acad Sci 1109:1-8. 2007
    ..Herein the nature and nurture of autoimmune diseases considered as a trait are reviewed, and a discussion is given on their multifactorial characteristics...
  46. pmc Cardiovascular disease in rheumatoid arthritis: a systematic literature review in latin america
    Juan Camilo Sarmiento-Monroy
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, 111221 Bogotá, Colombia
    Arthritis 2012:371909. 2012
    ..There is limited data about CVD and RA in LA. We propose to evaluate cardiovascular risk factors comprehensively in the Latin RA patient and to generate specific public health policies in order to diminish morbi-mortality rates...
  47. doi Autoimmune disease and gender: plausible mechanisms for the female predominance of autoimmunity
    Olga L Quintero
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia
    J Autoimmun 38:J109-19. 2012
    ..These hormonal changes as well as the genetic factors that could explain why women are more prone to develop ADs are herein reviewed...
  48. pmc Introducing polyautoimmunity: secondary autoimmune diseases no longer exist
    Adriana Rojas-Villarraga
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Kr 24 63 C 69 Third Floor, Bogota, Colombia
    Autoimmune Dis 2012:254319. 2012
    ..Polyautoimmunity is the term proposed for this association of disorders, which encompasses the concept of a common origin for these diseases...
  49. pmc Spondyloarthropathies in autoimmune diseases and vice versa
    Oscar M Pérez-Fernández
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Carrera 24 63 C 69, Bogota, Colombia
    Autoimmune Dis 2012:736384. 2012
    ..86%. In the ADs group, there were 5 patients with SpAs (0.46%). Our results suggest a lack of association between SpAs and ADs. Accordingly, SpAs might correspond more to autoinflammatory diseases rather than to ADs...
  50. ncbi [Impact of cardiovascular illness on hospitalization costs in patients with rheumatoid arthritis]
    Ricardo Pineda-Tamayo
    Unidad de Reumatologia, Clínica Universitaria Bolivariana, Facultad de Medicina, Universidad Pontificia Bolivariana, Medellin, Colombia
    Biomedica 24:366-74. 2004
    ..These data assist in the estimation of health care resources and in the selection of public health policies for the improvement of patient outcomes...
  51. ncbi Socioeconomic status. The relationship with health and autoimmune diseases
    Omar Javier Calixto
    Center for Autoimmune Diseases Research CREA, Mederi Hospital Universitario Mayor, Universidad del Rosario, Bogota, Colombia
    Autoimmun Rev 13:641-54. 2014
    ....
  52. ncbi [Polymorphism of TNF-alpha in autoimmunity and tuberculosis]
    Paula A Correa
    Unidad de Biología Celular e Inmunogenética, Corporacion para Investigaciones Biologicas, Medellin, Colombia
    Biomedica 24:43-51. 2004
    ..In addition, the data point towards a genetic selection in our population that might be maintained through dominant selection (heterozygote advantage) to infection by M. tuberculosis but susceptible to autoimmunity...
  53. ncbi The long pentraxin 3 and its role in autoimmunity
    Oscar Danilo Ortega-Hernandez
    Cellular Biology and Immunogenetics Unit CBIGU, Corporacion para Investigaciones Biologicas CIB, Cra 72A 78B 141, Medellin, Colombia
    Semin Arthritis Rheum 39:38-54. 2009
    ..To review the physiological and physiopathological roles of pentraxin 3 (PTX3), focusing on autoimmunity and vascular pathology...
  54. doi ZC3H12A (MCPIP1): molecular characteristics and clinical implications
    Ricardo A Cifuentes
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia
    Clin Chim Acta 411:1862-8. 2010
    ..ZC3H12A is a gene whose absence is related to autoimmune disorders and to other phenotypical alterations...
  55. ncbi Lupus mimickers
    Omar Javier Calixto
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia Mederi, Hospital Universitario Mayor, Bogota, Colombia
    Autoimmun Rev 13:865-72. 2014
    ..Herein we review and classify the current literature on lupus mimickers based on diverse etiologies which include infections, malign and benign neoplasms, medications, and vaccine-related reactions. ..
  56. doi Similar biotherapeutic products: overview and reflections
    Zayrho Desanvicente-Celis
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Carrera 24 63 C 69 Third Floor, Bogota, Colombia
    Immunotherapy 4:1841-57. 2012
    ..The establishment of a balance between a comprehensive CE for SBPs and their reference BPs, and the design of costeffective strategies to provide better access to BPs, should be the key goal for national regulatory authorities...
  57. pmc The autoimmune tautology: an in silico approach
    Ricardo A Cifuentes
    Center for Autoimmune Diseases Research CREA, School of Medicine and Health Sciences, Universidad del Rosario, Carrera 24, No 63 69 piso 3, Bogota, Colombia
    Autoimmune Dis 2012:792106. 2012
    ..Our results support the common origin of AIDs and the role of genes involved in apoptosis such as CTLA4, FASLG, and IL10...
  58. ncbi Endothelial nitric oxide synthase gene polymorphism is associated with systemic lupus erythematosus
    Norma C Serrano
    School of Medicine, Universidad Autónoma de Bucaramanga UNAB, Bucaramanga, Colombia
    J Rheumatol 31:2163-8. 2004
    ..eNOS gene polymorphism may affect both the synthesis of eNOS protein and its enzymatic activity. We examined the influence of eNOS gene polymorphisms on susceptibility to SLE...
  59. doi The simultaneous presence of IL-1B and TNFA two-positions risk haplotypes enhances the susceptibility for celiac disease
    Alejandra Claudia Cherñavsky
    Immunogenetic Laboratory, Hospital de Clinicas Jose de San Martin, Universidad de Buenos Aires, Av Cordoba 2351, 1120 Buenos Aires, Argentina
    Cytokine 42:48-54. 2008
    ..71) is associated with CD. Interestingly, our data suggest that the coexistence of both risk haplotypes seems to work synergistically (OR 29.59), which enhances the risk of developing CD...
  60. ncbi Genetic influence of PTPN22 R620W polymorphism in tuberculosis
    Luis M Gomez
    Instituto de Parasitologia y Biomedicina, Granada, Spain
    Hum Immunol 66:1242-7. 2005
    ..e., TST+ individuals), whereas the C allele may be a risk factor for development of overt TB. The results also indicate that an association opposite that between the PTPN22 polymorphism and TB exists between TB and autoimmunity...
  61. ncbi Physiological and pathological implications of laminins: from the gene to the protein
    María Carolina Páez
    Biomedical Research Center, School of Medicine at Universidad Autónoma de Bucaramanga, Bucaramanga, Colombia
    Autoimmunity 40:83-94. 2007
    ..Studies and hypothesis exploring the role of LM and their polymorphic genes on autoimmune diseases (AIDs) such as systemic lupus erythematosus and Sjögren's syndrome (SS) are also discussed...
  62. ncbi Autoimmunity and autoimmune disease: a Colombian construction beyond deconstructions
    Juan Manuel Anaya
    Autoimmun Rev 5:165-6. 2006
  63. ncbi Sjögren syndrome associated with hepatitis C virus: a multicenter analysis of 137 cases
    Manuel Ramos-Casals
    Department of Autoimmune Diseases, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, School of Medicine, University of Barcelona, Barcelona, Spain
    Medicine (Baltimore) 84:81-9. 2005
    ..We propose the term "SS secondary to HCV" when these patients fulfill the 2002 classification criteria for SS...
  64. ncbi Risk factors associated with pulmonary arterial hypertension in Colombian patients with systemic sclerosis: review of the literature
    Paola Coral-Alvarado
    Rheumatology Unit, Universidad Nacional de Colombia, Bogota, Colombia
    J Rheumatol 35:244-50. 2008
    ....
  65. ncbi Cutaneous vasculitis in primary Sjögren syndrome: classification and clinical significance of 52 patients
    Manuel Ramos-Casals
    Department of Autoimmune Diseases, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, School of Medicine, University of Barcelona, Barcelona, Spain
    Medicine (Baltimore) 83:96-106. 2004
    ..Life-threatening vasculitis was closely related to cryoglobulinemia...
  66. ncbi Education for patients with rheumatoid arthritis: is it worth it?
    Jose Cadena
    Arthritis Rheum 49:738-40. 2003
  67. ncbi A latitudinal gradient study of common anti-infectious agent antibody prevalence in Italy and Colombia
    Vitor Pordeus
    Pro Cardiaco Hospital Research and Training Center PROCEP, Rio de Janeiro, Brazil
    Isr Med Assoc J 10:65-8. 2008
    ..A negative relationship between latitude and infectious disease species richness has been suggested...
  68. ncbi Analysis of DC-SIGN (CD209) functional variants in patients with tuberculosis
    Luis M Gomez
    Instituto de Parasitologia y Biomedicina, Granada, Spain
    Hum Immunol 67:808-11. 2006
    ..We conclude that the studied polymorphisms are not relevant risk factors for developing tuberculosis in Northwestern Colombian individuals...