Frederick M Cohan

Summary

Publications

  1. ncbi request reprint Gradual evolution in bacteria: evidence from Bacillus systematics
    Michael Feldgarden
    Department of Biology, Wesleyan University, Middletown, CT 06459 0170, USA
    Microbiology 149:3565-73. 2003
  2. ncbi request reprint A systematics for discovering the fundamental units of bacterial diversity
    Frederick M Cohan
    Department of Biology, Wesleyan University, Middletown, Connecticut 06459 0170, USA
    Curr Biol 17:R373-86. 2007
  3. pmc Ecology of speciation in the genus Bacillus
    Nora Connor
    Department of Biology, Wesleyan University, Middletown, CT 06459, USA
    Appl Environ Microbiol 76:1349-58. 2010
  4. pmc Towards a conceptual and operational union of bacterial systematics, ecology, and evolution
    Frederick M Cohan
    Department of Biology, Wesleyan University, Middletown, CT 06459 0170, USA
    Philos Trans R Soc Lond B Biol Sci 361:1985-96. 2006
  5. doi request reprint The origins of ecological diversity in prokaryotes
    Frederick M Cohan
    Department of Biology, Wesleyan University, Middletown, CT 06459 0170, USA
    Curr Biol 18:R1024-34. 2008
  6. pmc Identifying the fundamental units of bacterial diversity: a paradigm shift to incorporate ecology into bacterial systematics
    Alexander Koeppel
    Departments of Biology and Mathematics and Computer Science, Wesleyan University, Middletown, CT 06459, USA
    Proc Natl Acad Sci U S A 105:2504-9. 2008
  7. ncbi request reprint Sexual isolation and speciation in bacteria
    Frederick M Cohan
    Department of Biology, Wesleyan University, Middletown, CT 06459 0170, USA
    Genetica 116:359-70. 2002
  8. doi request reprint Synthetic biology: now that we're creators, what should we create?
    Frederick M Cohan
    Department of Biology, Wesleyan University, Middletown, Connecticut, USA
    Curr Biol 20:R675-7. 2010
  9. pmc Speedy speciation in a bacterial microcosm: new species can arise as frequently as adaptations within a species
    Alexander F Koeppel
    Department of Biology, Wesleyan University, Middletown, CT 06459, USA
    ISME J 7:1080-91. 2013
  10. pmc The variable subdomain of Escherichia coli SecA functions to regulate SecA ATPase activity and ADP release
    Sanchaita Das
    Department of Molecular Biology and Biochemistry, Wesleyan University, Middletown, Connecticut, USA
    J Bacteriol 194:2205-13. 2012

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Gradual evolution in bacteria: evidence from Bacillus systematics
    Michael Feldgarden
    Department of Biology, Wesleyan University, Middletown, CT 06459 0170, USA
    Microbiology 149:3565-73. 2003
    ..A protocol is presented for identifying those modifications of gene expression and those gene acquisitions that are most likely to have played a role in adaptive evolution...
  2. ncbi request reprint A systematics for discovering the fundamental units of bacterial diversity
    Frederick M Cohan
    Department of Biology, Wesleyan University, Middletown, Connecticut 06459 0170, USA
    Curr Biol 17:R373-86. 2007
    ..This would establish a theory-based species unit that holds the dynamic properties broadly attributed to species outside of microbiology...
  3. pmc Ecology of speciation in the genus Bacillus
    Nora Connor
    Department of Biology, Wesleyan University, Middletown, CT 06459, USA
    Appl Environ Microbiol 76:1349-58. 2010
    ..subtilis-B. licheniformis clade: ES and AdaptML identified several newly discovered clades as ecotypes that are distinct from any recognized taxon...
  4. pmc Towards a conceptual and operational union of bacterial systematics, ecology, and evolution
    Frederick M Cohan
    Department of Biology, Wesleyan University, Middletown, CT 06459 0170, USA
    Philos Trans R Soc Lond B Biol Sci 361:1985-96. 2006
    ....
  5. doi request reprint The origins of ecological diversity in prokaryotes
    Frederick M Cohan
    Department of Biology, Wesleyan University, Middletown, CT 06459 0170, USA
    Curr Biol 18:R1024-34. 2008
    ..This effort will require development of universal approaches to hypothesize demarcations of ecotypes, and to confirm and characterize their ecological distinctness, without prior knowledge of a given clade's ecology...
  6. pmc Identifying the fundamental units of bacterial diversity: a paradigm shift to incorporate ecology into bacterial systematics
    Alexander Koeppel
    Departments of Biology and Mathematics and Computer Science, Wesleyan University, Middletown, CT 06459, USA
    Proc Natl Acad Sci U S A 105:2504-9. 2008
    ..Ecotype simulation provides a long-needed natural foundation for microbial ecology and systematics...
  7. ncbi request reprint Sexual isolation and speciation in bacteria
    Frederick M Cohan
    Department of Biology, Wesleyan University, Middletown, CT 06459 0170, USA
    Genetica 116:359-70. 2002
    ..Interspecific recombination may also foster speciation by introducing novel gene loci from divergent species, allowing invasion of new niches...
  8. doi request reprint Synthetic biology: now that we're creators, what should we create?
    Frederick M Cohan
    Department of Biology, Wesleyan University, Middletown, Connecticut, USA
    Curr Biol 20:R675-7. 2010
    ..The technology allows the introduction of easily transferable adaptive units, as well as sets of genes that have likely never been transferred successfully...
  9. pmc Speedy speciation in a bacterial microcosm: new species can arise as frequently as adaptations within a species
    Alexander F Koeppel
    Department of Biology, Wesleyan University, Middletown, CT 06459, USA
    ISME J 7:1080-91. 2013
    ..These results suggest near parity of anagenesis and cladogenesis rates in natural populations that are depauperate of bacterial diversity...
  10. pmc The variable subdomain of Escherichia coli SecA functions to regulate SecA ATPase activity and ADP release
    Sanchaita Das
    Department of Molecular Biology and Biochemistry, Wesleyan University, Middletown, Connecticut, USA
    J Bacteriol 194:2205-13. 2012
    ..Based on our findings, we discuss models whereby VAR allosterically regulates SecA DEAD motor function at SecYEG...
  11. ncbi request reprint What are bacterial species?
    Frederick M Cohan
    Department of Biology, Wesleyan University, Middletown, Connecticut 06459 0170, USA
    Annu Rev Microbiol 56:457-87. 2002
    ..These molecular methods suggest that a typical named species contains many ecotypes, each with the universal attributes of species. A named bacterial species is thus more like a genus than a species...
  12. doi request reprint Origins of bacterial diversity through horizontal genetic transfer and adaptation to new ecological niches
    Jane Wiedenbeck
    Department of Biology, Wesleyan University, Middletown, CT 06459, USA
    FEMS Microbiol Rev 35:957-76. 2011
    ....
  13. ncbi request reprint Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analyses
    Devaki Bhaya
    Department of Plant Biology, Carnegie Institution, Stanford, CA 94305, USA
    ISME J 1:703-13. 2007
    ....
  14. ncbi request reprint Opinion: Re-evaluating prokaryotic species
    Dirk Gevers
    Laboratory of Microbiology and the Bioinformatics and Evolutionary Genomics Research Group, Ghent University VIB, Ghent, Belgium
    Nat Rev Microbiol 3:733-9. 2005
    ..We also consider the potential, and difficulties, of assigning species status to biologically or ecologically meaningful sequence clusters...