Isabel Coelho

Summary

Publications

  1. ncbi request reprint No evidence of association or linkage disequilibrium between polymorphisms in the 5' upstream and coding regions of the dopamine D4 receptor gene and schizophrenia in a Portuguese population
    Alda M Ambrósio
    Center for Neuroscience of Coimbra, Department of Neurochemistry, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    Am J Med Genet B Neuropsychiatr Genet 125:20-4. 2004
  2. ncbi request reprint Nonparametric linkage analysis between schizophrenia and candidate genes of dopaminergic and serotonergic systems
    Alda M Ambrósio
    Department of Neurochemistry, University of Coimbra, Coimbra, Portugal
    CNS Spectr 9:302-8. 2004
  3. ncbi request reprint Family association study between DRD2 and DRD3 gene polymorphisms and schizophrenia in a Portuguese population
    Alda M Ambrósio
    Department of Neurochemistry, Faculty of Medicine, Center for Neuroscience of Coimbra, University of Coimbra, 3004 517 Coimbra, Portugal
    Psychiatry Res 125:185-91. 2004
  4. ncbi request reprint Lack of association or linkage disequilibrium between schizophrenia and polymorphisms in the 5-HT1Dalpha and 5-HT1Dbeta autoreceptor genes: family-based association study
    Alda M Ambrósio
    Center for Neuroscience of Coimbra, Department of Neurochemistry, Faculty of Medicine, University of Coimbra, 3004 517 Coimbra, Portugal
    Am J Med Genet B Neuropsychiatr Genet 128:1-5. 2004
  5. ncbi request reprint A linkage study between the GABAA beta2 and GABAA gamma2 subunit genes and major psychoses
    Alda M Ambrósio
    Unit of Clinical and Molecular Genetics, National Institute of Legal Medicine, Faculty of Medicine, University of Coimbra, Largo da Se Nova, 3000 213 Coimbra, Portugal
    CNS Spectr 10:57-61. 2005
  6. ncbi request reprint Genotypes at the APOE and SCA2 loci do not predict the course of multiple sclerosis in patients of Portuguese origin
    Monica Santos
    UnIGENe IBMC, Univ Porto
    Mult Scler 10:153-7. 2004
  7. ncbi request reprint NR4A2 and schizophrenia: lack of association in a Portuguese/Brazilian study
    Dina Ruano
    Health Sciences School, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal
    Am J Med Genet B Neuropsychiatr Genet 128:41-5. 2004

Collaborators

  • Catarina R Oliveira
  • Carlos N Pato
  • Alda M Ambrósio
  • Fabio Macciardi
  • James L Kennedy
  • Maria J Soares
  • Antonio Macedo
  • Jose Valente
  • Ana Dourado
  • Dina Ruano
  • Monica Santos
  • Nicole King
  • Maria H Azevedo
  • José Dinis
  • Luís Bigotte de Almeida
  • Maria Helena Azevedo
  • Maria João Soares
  • Jorge Sequeiros
  • Jose Figueiredo
  • Patricia Maciel
  • Michele T Pato
  • Ann Goodman
  • Angela Valença
  • António Valongueiro
  • Maria Ines Lobato
  • Marta Monteiro
  • Maria Teresa Matamá
  • Maria do Carmo Costa
  • Clarissa Gama
  • Jorge Pinto-Basto
  • Mara Helena Hutz
  • Maria Edite Rio
  • Paulo Belmonte-de-Abreu
  • Vítor Santos
  • Alfredo Sa
  • Maria José Sá
  • Cathy Barr
  • Joana Almeida Palha

Detail Information

Publications7

  1. ncbi request reprint No evidence of association or linkage disequilibrium between polymorphisms in the 5' upstream and coding regions of the dopamine D4 receptor gene and schizophrenia in a Portuguese population
    Alda M Ambrósio
    Center for Neuroscience of Coimbra, Department of Neurochemistry, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    Am J Med Genet B Neuropsychiatr Genet 125:20-4. 2004
    ..These data suggest that polymorphisms (-C616G, -C521T, and 48 bp repeat) at the DRD4 gene do not have a minor effect in the susceptibility to schizophrenia in our sample...
  2. ncbi request reprint Nonparametric linkage analysis between schizophrenia and candidate genes of dopaminergic and serotonergic systems
    Alda M Ambrósio
    Department of Neurochemistry, University of Coimbra, Coimbra, Portugal
    CNS Spectr 9:302-8. 2004
    ..This study was performed to assess the possible involvement of the dopamine receptor genes D2 (DRD2), D3, D4, serotonin receptor genes 1Da, 1Db, and 2A in the etiology of schizophrenia...
  3. ncbi request reprint Family association study between DRD2 and DRD3 gene polymorphisms and schizophrenia in a Portuguese population
    Alda M Ambrósio
    Department of Neurochemistry, Faculty of Medicine, Center for Neuroscience of Coimbra, University of Coimbra, 3004 517 Coimbra, Portugal
    Psychiatry Res 125:185-91. 2004
    ..Therefore, we conclude that neither the DRD2 nor the DRD3 gene polymorphisms investigated are associated with schizophrenia in our sample...
  4. ncbi request reprint Lack of association or linkage disequilibrium between schizophrenia and polymorphisms in the 5-HT1Dalpha and 5-HT1Dbeta autoreceptor genes: family-based association study
    Alda M Ambrósio
    Center for Neuroscience of Coimbra, Department of Neurochemistry, Faculty of Medicine, University of Coimbra, 3004 517 Coimbra, Portugal
    Am J Med Genet B Neuropsychiatr Genet 128:1-5. 2004
    ..Thus, our data provide no support for the hypothesis that polymorphisms at 5-HT1Dalpha (TaqI) and 5-HT1Dbeta (T261G and G861C) genes contributes to susceptibility to schizophrenia in the Portuguese population...
  5. ncbi request reprint A linkage study between the GABAA beta2 and GABAA gamma2 subunit genes and major psychoses
    Alda M Ambrósio
    Unit of Clinical and Molecular Genetics, National Institute of Legal Medicine, Faculty of Medicine, University of Coimbra, Largo da Se Nova, 3000 213 Coimbra, Portugal
    CNS Spectr 10:57-61. 2005
    ..Alterations of the gamma-aminobutyric acid (GABA) system have been implicated in the pathophysiology of major psychoses...
  6. ncbi request reprint Genotypes at the APOE and SCA2 loci do not predict the course of multiple sclerosis in patients of Portuguese origin
    Monica Santos
    UnIGENe IBMC, Univ Porto
    Mult Scler 10:153-7. 2004
    ..However, globally in the Portuguese population, the APOE and SCA2 genes do not seem to be useful in the clinical context as prognostic markers of this disorder...
  7. ncbi request reprint NR4A2 and schizophrenia: lack of association in a Portuguese/Brazilian study
    Dina Ruano
    Health Sciences School, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal
    Am J Med Genet B Neuropsychiatr Genet 128:41-5. 2004
    ..The study failed to identify any of the described mutations in patients or controls. Nevertheless, these negative results do not exclude altered expression of nuclear receptors in schizophrenia or the presence of other mutations...