William R Clark

Summary

Publications

  1. ncbi Continuous renal replacement techniques
    William R Clark
    NxStage Medical, Inc, Lawrence, Mass, USA
    Contrib Nephrol 144:264-77. 2004
  2. ncbi Dose determinants in continuous renal replacement therapy
    William R Clark
    NxStage Medical, Inc Lawrence, MA, USA
    Artif Organs 27:815-20. 2003
  3. ncbi The NxStage System One
    William R Clark
    NxStage Medical Inc, 439 South Union Street, Lawrence, MA 01843, USA
    Semin Dial 17:167-70. 2004
  4. ncbi Middle molecules and small-molecular-weight proteins in ESRD: properties and strategies for their removal
    William R Clark
    NxStage Medical, Inc, Indiana University School of Medicine, Indianapolis, USA
    Adv Ren Replace Ther 10:270-8. 2003
  5. ncbi Low-molecular weight proteins in end-stage renal disease: potential toxicity and dialytic removal mechanisms
    William R Clark
    Renal Division, Baxter Healthcare Corporation, McGaw Park, Indiana, USA
    J Am Soc Nephrol 13:S41-7. 2002
  6. ncbi Recent clinical advances in the management of critically ill patients with acute renal failure
    William R Clark
    Nephrology Division, Indiana University School of Medicine, Indianapolis, IN, USA
    Blood Purif 24:487-98. 2006
  7. ncbi Kinetic comparison of different acute dialysis therapies
    Zhijie Liao
    Department of Mechanical Engineering, University of Kentucky, Lexington, KY, USA
    Artif Organs 27:802-7. 2003
  8. ncbi Factors influencing low-molecular-weight solute clearance during hemodialysis
    Zhongping Huang
    Department of Mechanical Engineering, Widener University, Chester, Pennsylvania 19013, USA
    Hemodial Int 9:332-7. 2005
  9. ncbi Determinants of small solute clearance in hemodialysis
    Zhongping Huang
    Center for Biomedical Engineering, University of Kentucky, Louisville, Kentucky, USA
    Semin Dial 18:30-5. 2005
  10. ncbi A new method to evaluate the local clearance at different annular rings inside hemodialyzers
    Zhongping Huang
    Department of Mechanical Engineering, University of Kentucky, Lexington, Kentucky 40506, USA
    ASAIO J 49:692-7. 2003

Detail Information

Publications17

  1. ncbi Continuous renal replacement techniques
    William R Clark
    NxStage Medical, Inc, Lawrence, Mass, USA
    Contrib Nephrol 144:264-77. 2004
  2. ncbi Dose determinants in continuous renal replacement therapy
    William R Clark
    NxStage Medical, Inc Lawrence, MA, USA
    Artif Organs 27:815-20. 2003
    ..Specifically, differences between postdilution and predilution CVVH will be highlighted, and the importance of blood flow rate in dose delivery for these therapies will be discussed...
  3. ncbi The NxStage System One
    William R Clark
    NxStage Medical Inc, 439 South Union Street, Lawrence, MA 01843, USA
    Semin Dial 17:167-70. 2004
    ..In both the chronic and acute care environments, the System One presents clinicians with a new platform for delivering patient therapy improvements within real-world constraints...
  4. ncbi Middle molecules and small-molecular-weight proteins in ESRD: properties and strategies for their removal
    William R Clark
    NxStage Medical, Inc, Indiana University School of Medicine, Indianapolis, USA
    Adv Ren Replace Ther 10:270-8. 2003
    ....
  5. ncbi Low-molecular weight proteins in end-stage renal disease: potential toxicity and dialytic removal mechanisms
    William R Clark
    Renal Division, Baxter Healthcare Corporation, McGaw Park, Indiana, USA
    J Am Soc Nephrol 13:S41-7. 2002
    ..Finally, an overview of LMWP removal mechanisms for both hemodialysis and the convective therapies is provided...
  6. ncbi Recent clinical advances in the management of critically ill patients with acute renal failure
    William R Clark
    Nephrology Division, Indiana University School of Medicine, Indianapolis, IN, USA
    Blood Purif 24:487-98. 2006
    ..Significant progress has been made in the field of renal replacement therapy for critically ill patients with acute renal failure (ARF) over the past few years. This review highlights these developments...
  7. ncbi Kinetic comparison of different acute dialysis therapies
    Zhijie Liao
    Department of Mechanical Engineering, University of Kentucky, Lexington, KY, USA
    Artif Organs 27:802-7. 2003
    ..After clinical validation, the quantification method presented in this article could be a useful tool to assist in the dialytic management of critically ill ARF patients...
  8. ncbi Factors influencing low-molecular-weight solute clearance during hemodialysis
    Zhongping Huang
    Department of Mechanical Engineering, Widener University, Chester, Pennsylvania 19013, USA
    Hemodial Int 9:332-7. 2005
    ..Although the focus of the review is on the manner in which dialyzer characteristics influence small solute clearances, factors related to other aspects of the extracorporeal circuit and to the patient will also be discussed...
  9. ncbi Determinants of small solute clearance in hemodialysis
    Zhongping Huang
    Center for Biomedical Engineering, University of Kentucky, Louisville, Kentucky, USA
    Semin Dial 18:30-5. 2005
    ..Although the focus of the review is on the manner in which dialyzer characteristics influence small solute clearances, factors related to other aspects of the extracorporeal circuit and to the patient will also be discussed...
  10. ncbi A new method to evaluate the local clearance at different annular rings inside hemodialyzers
    Zhongping Huang
    Department of Mechanical Engineering, University of Kentucky, Lexington, Kentucky 40506, USA
    ASAIO J 49:692-7. 2003
    ..Hollow fibers at different locations did contribute differently to the solute clearance, which may be caused by the channeling of dialysate flow. A careful design of the dialyzer to minimize the channeling is needed...
  11. ncbi Effect of flow baffles on the dialysate flow distribution of hollow-fiber hemodialyzers: a nonintrusive experimental study using MRI
    Churn K Poh
    Department of Mechanical Engineering, University of Kentucky, Lexington, KY, USA
    J Biomech Eng 125:481-9. 2003
    ....
  12. ncbi A numerical and experimental study of mass transfer in the artificial kidney
    Zhijie Liao
    Department of Mechanical Engineering, University of Kentucky, Lexington, KY 40506, USA
    J Biomech Eng 125:472-80. 2003
    ..This numerical model presented a clear insight view of mass transfer in an artificial kidney and may be used to help design an optimal artificial kidney and its operation conditions to improve hemodialysis...
  13. ncbi Effect of spacer yarns on the dialysate flow distribution of hemodialyzers: a magnetic resonance imaging study
    Churn K Poh
    Department of Mechanical Engineering, University of Kentucky, Lexington, KY 40506 0108, USA
    ASAIO J 49:440-8. 2003
    ..Our experimental results showed that these velocity imaging techniques provide an innovative, nonintrusive tool for characterizing flow distribution in hemodialyzers...
  14. ncbi The Acute Dialysis Quality Initiative--part IV: membranes for CRRT
    William R Clark
    Renal Division, Baxter Healthcare Corporation, Nephrology Section, Indianapolis, IN, USA
    Adv Ren Replace Ther 9:265-7. 2002
    ..These and other issues should be the subject of future clinical research efforts...
  15. ncbi Properties of membranes used for hemodialysis therapy
    William R Clark
    Renal Division, Baxter Healthcare Corp, McGaw Park, Illinois, USA
    Semin Dial 15:191-5. 2002
    ..A general overview of membrane-related determinants of dialyzer performance is first presented, followed by a discussion of specific characteristics of some of the more commonly used membranes and dialyzers...
  16. ncbi Determinants of uraemic toxin removal
    William R Clark
    Renal Division, Baxter Healthcare Corp, McGaw Park, IL, USA
    Nephrol Dial Transplant 17:30-4. 2002
    ..All of these issues will be major considerations as new dialytic therapies for end-stage renal disease patients are developed and implemented...
  17. ncbi Solute removal by hollow-fiber dialyzers
    William R Clark
    Gambro Inc, Lakewood, Colo, USA
    Contrib Nephrol 158:20-33. 2007
    ..The remainder of the chapter emphasizes the major determinants of hollow-fiber dialyzer performance...