Diane M Citron

Summary

Publications

  1. ncbi request reprint Pre-molecular identification: ignorance was bliss?
    Diane M Citron
    R M Alden Research Lab, Culver City, CA 90230, United States
    Anaerobe 18:189-91. 2012
  2. pmc In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria
    D M Citron
    R M Alden Research Laboratory, 6133 Bristol Parkway, Suite 175, Culver City, CA 90404, USA
    Antimicrob Agents Chemother 54:1627-32. 2010
  3. ncbi request reprint Comparative in vitro activity of faropenem and 11 other antimicrobial agents against 405 aerobic and anaerobic pathogens isolated from skin and soft tissue infections from animal and human bites
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica UCLA Medical Center and the UCLA School of Medicine, Los Angeles, CA 90073, USA
    J Antimicrob Chemother 50:411-20. 2002
  4. pmc In vitro activities of the new semisynthetic glycopeptide telavancin (TD-6424), vancomycin, daptomycin, linezolid, and four comparator agents against anaerobic gram-positive species and Corynebacterium spp
    Ellie J C Goldstein
    R M Alden Research Laboratory, 2021 Santa Monica Blvd, Suite 740 East, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 48:2149-52. 2004
  5. ncbi request reprint Fusobacterium canifelinum sp. nov., from the oral cavity of cats and dogs
    Georg Conrads
    R M Alden Research Laboratory, Santa Monica, California, USA
    Syst Appl Microbiol 27:407-13. 2004
  6. pmc In vitro activities of daptomycin, vancomycin, and penicillin against Clostridium difficile, C. perfringens, Finegoldia magna, and Propionibacterium acnes
    Kerin L Tyrrell
    R M Alden Research Laboratory, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 50:2728-31. 2006
  7. pmc In vitro activities of dalbavancin and 12 other agents against 329 aerobic and anaerobic gram-positive isolates recovered from diabetic foot infections
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 50:2875-9. 2006
  8. pmc In vitro activity of ceftobiprole against aerobic and anaerobic strains isolated from diabetic foot infections
    Ellie J C Goldstein
    R M Alden Research Laboratory, 2021 Santa Monica Blvd, 740 East, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 50:3959-62. 2006
  9. pmc In vitro activity of TD-1792, a multivalent glycopeptide-cephalosporin antibiotic, against 377 strains of anaerobic bacteria and 34 strains of Corynebacterium species
    Kerin L Tyrrell
    R M Alden Research Lab, Culver City, California, USA
    Antimicrob Agents Chemother 56:2194-7. 2012
  10. pmc In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds
    Ellie J C Goldstein
    R M Alden Research Laboratory, 2021 Santa Monica Blvd, 740 East, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 52:761-6. 2008

Detail Information

Publications62

  1. ncbi request reprint Pre-molecular identification: ignorance was bliss?
    Diane M Citron
    R M Alden Research Lab, Culver City, CA 90230, United States
    Anaerobe 18:189-91. 2012
    ..Some of the newly described species have been recovered from blood cultures, showing pathogenic potential, and posing a challenge for identification...
  2. pmc In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria
    D M Citron
    R M Alden Research Laboratory, 6133 Bristol Parkway, Suite 175, Culver City, CA 90404, USA
    Antimicrob Agents Chemother 54:1627-32. 2010
    ..Ceftaroline showed potent activity against a broad spectrum of anaerobes encountered in respiratory, skin, and soft tissue infections...
  3. ncbi request reprint Comparative in vitro activity of faropenem and 11 other antimicrobial agents against 405 aerobic and anaerobic pathogens isolated from skin and soft tissue infections from animal and human bites
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica UCLA Medical Center and the UCLA School of Medicine, Los Angeles, CA 90073, USA
    J Antimicrob Chemother 50:411-20. 2002
    ..three strains)...
  4. pmc In vitro activities of the new semisynthetic glycopeptide telavancin (TD-6424), vancomycin, daptomycin, linezolid, and four comparator agents against anaerobic gram-positive species and Corynebacterium spp
    Ellie J C Goldstein
    R M Alden Research Laboratory, 2021 Santa Monica Blvd, Suite 740 East, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 48:2149-52. 2004
    ..casei were >1 microg/ml. The MIC(90) of TD-6424 for all strains tested was </=2 microg/ml. TD-6424 has potential for use against infections with gram-positive anaerobes and deserves further clinical evaluation...
  5. ncbi request reprint Fusobacterium canifelinum sp. nov., from the oral cavity of cats and dogs
    Georg Conrads
    R M Alden Research Laboratory, Santa Monica, California, USA
    Syst Appl Microbiol 27:407-13. 2004
    ..The results indicate that the novel strains belong to a distinct species, closely related to Fusobacterium nucleatum. The species Fusobacterium canifelinum sp. nov. is proposed, with strain ATCC BAA 689T as the type strain...
  6. pmc In vitro activities of daptomycin, vancomycin, and penicillin against Clostridium difficile, C. perfringens, Finegoldia magna, and Propionibacterium acnes
    Kerin L Tyrrell
    R M Alden Research Laboratory, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 50:2728-31. 2006
    ..3 to 2.9 log at 24 h. Vancomycin was not bactericidal for C. perfringens; however, daptomycin showed bactericidal activity as early as 1 h at four and eight times the MIC and at 2 and 4 h at two and four times the MIC...
  7. pmc In vitro activities of dalbavancin and 12 other agents against 329 aerobic and anaerobic gram-positive isolates recovered from diabetic foot infections
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 50:2875-9. 2006
    ..5 and 1 microg/ml for vancomycin, 4 and 4 microg/ml for linezolid, 0.5 and 0.5 microg/ml for daptomycin, and 0.25 and >8 microg/ml for clindamycin...
  8. pmc In vitro activity of ceftobiprole against aerobic and anaerobic strains isolated from diabetic foot infections
    Ellie J C Goldstein
    R M Alden Research Laboratory, 2021 Santa Monica Blvd, 740 East, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 50:3959-62. 2006
    ..5; Anaerococcus prevotii, 0.125; Finegoldia magna, 0.5; Peptoniphilus asaccharolyticus, 1; Peptostreptococcus anaerobius, 4; Escherichia coli and Enterobacter species, 0.125; Klebsiella species, 2; and Pseudomonas aeruginosa, 8...
  9. pmc In vitro activity of TD-1792, a multivalent glycopeptide-cephalosporin antibiotic, against 377 strains of anaerobic bacteria and 34 strains of Corynebacterium species
    Kerin L Tyrrell
    R M Alden Research Lab, Culver City, California, USA
    Antimicrob Agents Chemother 56:2194-7. 2012
    ..Against nearly all Gram-positive strains, TD-1792 had an MIC₉₀ of 0.25 μg/ml and was typically 3 to 7 dilutions more active than vancomycin and daptomycin...
  10. pmc In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds
    Ellie J C Goldstein
    R M Alden Research Laboratory, 2021 Santa Monica Blvd, 740 East, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 52:761-6. 2008
    ..The MIC(50) and MIC(90) values were < or =0.125 microg/ml for methicillin-sensitive Staphylococcus aureus and all streptococci and 0.25/1 for Bacteroides fragilis...
  11. pmc In vitro activities of garenoxacin (BMS-284756) against 170 clinical isolates of nine Pasteurella species
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica University of California, Los Angeles, Medical Center, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 46:3068-70. 2002
    ..Cefoxitin required 1 micro g/ml for inhibition of 51 of 182 (29%) of strains, and 3 strains (also beta-lactamase producers) were resistant to doxycycline...
  12. pmc In vitro activities of Garenoxacin (BMS 284756) against 108 clinical isolates of Gardnerella vaginalis
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica University of California Los Angeles Medical Center, 90404, USA
    Antimicrob Agents Chemother 46:3995-6. 2002
    ..Twenty-eight percent of isolates (31 of 108) were resistant to metronidazole, and 44% were resistant to doxycycline. All were susceptible to clindamycin and ampicillin-sulbactam...
  13. doi request reprint Comparative in vitro activity of ceftaroline, ceftaroline-avibactam, and other antimicrobial agents against aerobic and anaerobic bacteria cultured from infected diabetic foot wounds
    Ellie J C Goldstein
    R M Alden Research Laboratory, Culver City, CA 90230, USA
    Diagn Microbiol Infect Dis 76:347-51. 2013
    ..The addition of avibactam provides an increased spectrum of activity including the beta-lactamase producing Prevotella, Bacteroides fragilis and ceftaroline resistant gram-negative enteric organisms...
  14. pmc Comparative in vitro activities of GSK2251052, a novel boron-containing leucyl-tRNA synthetase inhibitor, against 916 anaerobic organisms
    Ellie J C Goldstein
    RM Alden Research Laboratory, Culver City, California, USA
    Antimicrob Agents Chemother 57:2401-4. 2013
    ..All Clostridium perfringens strains had GSK2251052 MICs of >32 μg/ml. There was no relationship between increased MICs for any other antibiotics and that of GSK2251052...
  15. pmc Ceftaroline versus isolates from animal bite wounds: comparative in vitro activities against 243 isolates, including 156 Pasteurella species isolates
    Ellie J C Goldstein
    R M Alden Research Laboratory, Culver City, CA, USA
    Antimicrob Agents Chemother 56:6319-23. 2012
    ..125 μg/ml against all bite isolates tested. Ceftaroline has potential clinical utility against infections involving P. multocida, other Pasteurella species, and aerobic Gram-positive isolates, including S. aureus...
  16. doi request reprint Infection after elective colorectal surgery: bacteriological analysis of failures in a randomized trial of cefotetan vs. ertapenem prophylaxis
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, California 90404, USA
    Surg Infect (Larchmt) 10:111-8. 2009
    ..001). Failures of prophylaxis were thought to involve organisms resistant to both antimicrobial agents, isolated most often from deep or superficial incision sites...
  17. pmc Comparative in vitro susceptibilities of 396 unusual anaerobic strains to tigecycline and eight other antimicrobial agents
    Ellie J C Goldstein
    RM Alden Research Laboratory, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 50:3507-13. 2006
    ..It was active against all gram-positive strains and 228 of 232 gram-negative anaerobes at < or =1 microg/ml. One strain of Prevotella oralis was nonsusceptible at 8 microg/ml...
  18. ncbi request reprint In vitro activity of gemifloxacin compared to seven other oral antimicrobial agents against aerobic and anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitis
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica UCLA Medical Center, Santa Monica, CA 90404, USA
    Diagn Microbiol Infect Dis 42:113-8. 2002
    ..All fusobacteria were susceptible to < or =0.25 ug/mL of gemifloxacin. Based on our in vitro study results, we conclude that gemifloxacin may offer a therapeutic alternative for sinus infections...
  19. pmc Comparative in vitro activities of ertapenem (MK-0826) against 469 less frequently identified anaerobes isolated from human infections
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica UCLA Medical Center, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 46:1136-40. 2002
    ..Only 4 of 14 Clostridium difficile, 1 of 11 Clostridium innocuum, and 4 of 6 Lactobacillus sp. strains required ertapenem concentrations of > or = 8 microg/ml for inhibition...
  20. ncbi request reprint In vitro activity of 11 antibiotics against 74 anaerobes isolated from pediatric intra-abdominal infections
    Ellie J C Goldstein
    R M Alden Research Laboratory, 2021 Santa Monica Blvd, 740E, Santa Monica, CA 90404, USA
    Anaerobe 12:63-6. 2006
    ..Cefoxitin had moderate activity against B. fragilis but poor activity against Bacteroides thetaiotaomicron and other B. fragilis group isolates...
  21. doi request reprint Virulence characteristics of community-associated Staphylococcus aureus and in vitro activities of moxifloxacin alone and in combination against community-associated and healthcare-associated meticillin-resistant and -susceptible S. aureus
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, CA 90404, USA
    J Med Microbiol 57:452-6. 2008
    ..The FICI values for doxycycline were 3-6 for 32/34 strains, indicating antagonism, suggesting that it should not be used in combination with moxifloxacin...
  22. doi request reprint Comparative in vitro activity of REP3123 against Clostridium difficile and other anaerobic intestinal bacteria
    Diane M Citron
    R M Alden Research Laboratory, Culver City, CA 90230, USA
    J Antimicrob Chemother 63:972-6. 2009
    ..The aim of this study was to determine the anaerobic spectrum of activity of REP3123, a novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria...
  23. pmc Comparative in vitro activities of XRP 2868, pristinamycin, quinupristin-dalfopristin, vancomycin, daptomycin, linezolid, clarithromycin, telithromycin, clindamycin, and ampicillin against anaerobic gram-positive species, actinomycetes, and lactobacilli
    Ellie J C Goldstein
    R M Alden Research Laboratory, 2021 Santa Monica Blvd, Suite 740 East, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 49:408-13. 2005
    ..Depending on its pharmacokinetics and pharmacodynamics, XRP 2868 has potential for use against infections with gram-positive anaerobes and deserves further clinical evaluation...
  24. ncbi request reprint General microbiology and in vitro susceptibility of anaerobes isolated from complicated skin and skin-structure infections in patients enrolled in a comparative trial of ertapenem versus piperacillin-tazobactam
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, CA, 90404, USA
    Clin Infect Dis 35:S119-25. 2002
    ..9% to piperacillin-tazobactam. Ertapenem had excellent in vitro activity against the most common aerobic pathogens and almost all anaerobes recovered from patients with infections of the skin and skin structures...
  25. pmc In vitro activities of telithromycin and 10 oral agents against aerobic and anaerobic pathogens isolated from antral puncture specimens from patients with sinusitis
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 47:1963-7. 2003
    ..Telithromycin may offer a therapeutic alternative for sinus infections, including those due to erythromycin-resistant pneumococci...
  26. pmc In vitro activities of dalbavancin and nine comparator agents against anaerobic gram-positive species and corynebacteria
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 47:1968-71. 2003
    ..0.25 microg/ml. Dalbavancin was 1 to 3 dilutions more active than vancomycin against most strains. Dalbavancin exhibited excellent activity against gram-positive strains tested and warrants clinical evaluation...
  27. pmc Evaluation of cycloserine-cefoxitin fructose agar (CCFA), CCFA with horse blood and taurocholate, and cycloserine-cefoxitin mannitol broth with taurocholate and lysozyme for recovery of Clostridium difficile isolates from fecal samples
    Kerin L Tyrrell
    RM Alden Research Laboratory, Culver City, California, USA
    J Clin Microbiol 51:3094-6. 2013
    ..Compared to CCFA, CCFA-HT enhanced C. difficile growth and improved recovery by 4%. In a separate study, 9% (8/91) of stool samples previously C. difficile negative on plate medium were C. difficile positive when cultured in CCMB-TAL. ..
  28. pmc In vitro activities of CB-183,315, vancomycin, and metronidazole against 556 strains of Clostridium difficile, 445 other intestinal anaerobes, and 56 Enterobacteriaceae species
    Diane M Citron
    RM Alden Research Lab, Culver City, California, USA
    Antimicrob Agents Chemother 56:1613-5. 2012
    ..The CB-183,315 MIC(90) for Clostridium difficile was 0.5 μg/ml. Its lack of activity against normal fecal organisms makes it a promising new agent for treating C. difficile...
  29. pmc Comparative in vitro activities of LFF571 against Clostridium difficile and 630 other intestinal strains of aerobic and anaerobic bacteria
    Diane M Citron
    RM Alden Research Lab, Culver City, California, USA
    Antimicrob Agents Chemother 56:2493-503. 2012
    ..MIC(90) for S. pyogenes and other streptococci was 16 and >32 μg/ml, respectively. LFF571 and fidaxomicin were generally less active against Gram-negative anaerobes...
  30. pmc In vitro activities of iodonium salts against oral and dental anaerobes
    Ellie J C Goldstein
    R M Alden Research Laboratory, 2021 Santa Monica Blvd, Suite 740 E, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 48:2766-70. 2004
    ..Iodonium salts 3, 4, 5, 9, and 10 had in vitro activities comparable to that of chlorhexidine against most isolates. These compounds may be suitable for incorporation into an oral mouthwash...
  31. ncbi request reprint Bactericidal activity of telavancin, vancomycin and metronidazole against Clostridium difficile
    Ellie J C Goldstein
    R M Alden Research Laboratory, Culver City, CA 90230, USA
    Anaerobe 16:220-2. 2010
    ..Although telavancin MICs were 2-8 times lower than vancomycin, both demonstrated similar bacteriostatic activity against C. difficile while metronidazole was bactericidal...
  32. pmc Broth microdilution and disk diffusion tests for susceptibility testing of Pasteurella species isolated from human clinical specimens
    Diane M Citron
    R M Alden Research Lab, 2001 Santa Monica Blvd, Suite 685W, Santa Monica, CA 90404, USA
    J Clin Microbiol 43:2485-8. 2005
    ..Both methods appear reliable for testing susceptibilities of Pasteurella species...
  33. pmc Clostridium aldenense sp. nov. and Clostridium citroniae sp. nov. isolated from human clinical infections
    Yumi A Warren
    R M Alden Research Laboratory, 2001 Santa Monica Blvd, Suite 685W, Santa Monica, CA 90404, USA
    J Clin Microbiol 44:2416-22. 2006
    ..The type strain of C. aldenense is RMA 9741 (ATCC BAA-1318; CCUG 52204), and the type strain of C. citroniae is RMA 16102 (ATCC BAA-1317; CCUG 52203)...
  34. pmc In vitro activity of moxifloxacin against 923 anaerobes isolated from human intra-abdominal infections
    Ellie J C Goldstein
    R M Alden Research Laboratory, 2021 Santa Monica Blvd, Suite 740 East, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 50:148-55. 2006
    ..Overall, moxifloxacin was active against 763 of 923 (83%) of strains at < or = 2 microg/ml, supporting its use as a monotherapy for some community-acquired intra-abdominal infections...
  35. pmc Comparative in vitro activities of retapamulin (SB-275833) against 141 clinical isolates of Propionibacterium spp., including 117 P. acnes isolates
    Ellie J C Goldstein
    R M Alden Research Laboratory, 2021 Santa Monica Blvd Suite 740 E, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 50:379-81. 2006
    ....
  36. pmc Bacteriology of moderate-to-severe diabetic foot infections and in vitro activity of antimicrobial agents
    Diane M Citron
    R M Alden Research Laboratory, 2001 Santa Monica Blvd, Suite 685W, Santa Monica CA 90404, USA
    J Clin Microbiol 45:2819-28. 2007
    ..Moderate-to-severe DFIs are typically polymicrobial, and almost half include anaerobes. Our antibiotic susceptibility results can help to inform therapeutic choices...
  37. doi request reprint Re-assessment of phenotypic identifications of Bacteroides putredinis to Alistipes species using molecular methods
    Kerin L Tyrrell
    R M Alden Research Laboratory, Culver City, CA 90230, USA
    Anaerobe 17:130-4. 2011
    ..Pigment production was not a reliable test for those Alistipes strains that are described as pigment producers...
  38. pmc Comparative in vitro activities of SMT19969, a new antimicrobial agent, against Clostridium difficile and 350 gram-positive and gram-negative aerobic and anaerobic intestinal flora isolates
    Ellie J C Goldstein
    R M Alden Research Laboratory, Culver City, California, USA
    Antimicrob Agents Chemother 57:4872-6. 2013
    ..Gram-positive aerobic cocci (Staphylococcus aureus, Enterococcus faecalis, E. faecium, and streptococci) showed high SMT19969 MIC90 values (128 to >512 μg/ml). ..
  39. pmc In vitro activity of Biapenem plus RPX7009, a carbapenem combined with a serine β-lactamase inhibitor, against anaerobic bacteria
    Ellie J C Goldstein
    RM Alden Research Laboratory, Culver City, California, USA
    Antimicrob Agents Chemother 57:2620-30. 2013
    ..Biapenem-RPX7009 showed activity comparable to that of imipenem and was superior to meropenem, doripenem, and ertapenem against imipenem-nonsusceptible Bacteroides spp...
  40. pmc Antimicrobial activities of fidaxomicin
    Ellie J C Goldstein
    RM Alden Research Laboratory, Culver City, CA, USA
    Clin Infect Dis 55:S143-8. 2012
    ..Fidaxomicin has little or no activity against gram-negative aerobes and anaerobes or yeast...
  41. pmc In vitro activities of daptomycin, vancomycin, quinupristin- dalfopristin, linezolid, and five other antimicrobials against 307 gram-positive anaerobic and 31 Corynebacterium clinical isolates
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 47:337-41. 2003
    ..innocuum and lactobacillus strains and quinupristin-dalfopristin- and linezolid-resistant C. difficile strains...
  42. ncbi request reprint In vitro activity of azithromycin and nine comparator agents against 296 strains of oral anaerobes and 31 strains of Eikenella corrodens
    C Vreni Merriam
    R M Alden Research Laboratory, Santa Monica, CA 90404, USA
    Int J Antimicrob Agents 28:244-8. 2006
    ..Minimum inhibitory concentrations obtained on agar adjusted to pH 8 were generally one dilution lower than those obtained on agar at pH 7...
  43. ncbi request reprint 16S-23S rRNA gene internal transcribed spacer sequences for analysis of the phylogenetic relationships among species of the genus Porphyromonas
    Georg Conrads
    R M Alden Research Laboratory, Santa Monica, CA 90404, USA
    Int J Syst Evol Microbiol 55:607-13. 2005
    ..Moreover, the proposal of alpha-fucosidase-negative P. asaccharolytica strains as a new species should also be considered...
  44. pmc Biochemical differentiation and comparison of Desulfovibrio species and other phenotypically similar genera
    Yumi A Warren
    R M Alden Research Lab, 2001 Santa Monica Blvd, Suite 685W, Santa Monica, CA 90404, USA
    J Clin Microbiol 43:4041-5. 2005
    ..These simple tests were useful for characterizing the Desulfovibrio species and differentiating them from other phenotypically similar genera...
  45. doi request reprint Activity of a novel carbapenem, doripenem, against anaerobic pathogens
    Ellie J C Goldstein
    RM Alden Research Laboratory, Culver City, CA 90230, USA
    Diagn Microbiol Infect Dis 63:447-54. 2009
    ..and similar to imipenem". Doripenem activity against anaerobes seems comparable with the other extant carbapenems. Although resistance among anaerobic bacteria to this agent is possible, it remains relatively rare...
  46. doi request reprint Clinical efficacy and correlation of clinical outcomes with in vitro susceptibility for anaerobic bacteria in patients with complicated intra-abdominal infections treated with moxifloxacin
    Ellie J C Goldstein
    R M Alden Research Laboratory, Culver City, California, USA
    Clin Infect Dis 53:1074-80. 2011
    ..Recent in vitro studies have reported increasing moxifloxacin resistance of Bacteroides species, thereby cautioning empiric use in infections with these organisms...
  47. doi request reprint Activity of garenoxacin against 536 unusual anaerobes including 128 recovered from acute pelvic infections
    Ellie J C Goldstein
    R M Alden Research Laboratory, Culver City, CA 90230, USA
    Diagn Microbiol Infect Dis 70:131-6. 2011
    ..russii (cat bites), and 6/9 Actinomyces israelii. Overall, garenoxacin showed good activity against the isolates studied and has potential utility in mixed aerobic/anaerobic infections...
  48. ncbi request reprint Peptoniphilus coxii sp. nov. and Peptoniphilus tyrrelliae sp. nov. isolated from human clinical infections
    Diane M Citron
    R M Alden Research Laboratory, Culver City, CA 90230, USA
    Anaerobe 18:244-8. 2012
    ..nov. The type strains are P. coxii sp. nov., RMA 16757(T) (= JCM 16892(T) = CCUG 59622(T) = ATCC BAA-2106(T)) and P. tyrrelliae sp. nov., RMA 19911(T) (= JCM 16893(T) = CCUG 59621(T) = ATCC BAA-2105(T))...
  49. ncbi request reprint National hospital survey of anaerobic culture and susceptibility methods: III
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, CA 90404, USA
    Anaerobe 14:68-72. 2008
    ....
  50. pmc In vitro activity of ceftazidime-NXL104 against 396 strains of beta-lactamase-producing anaerobes
    Diane M Citron
    RM Alden Research Laboratory, Culver City, California 90230, USA
    Antimicrob Agents Chemother 55:3616-20. 2011
    ..Although CAZ-NXL104 had limited activity against most anaerobic strains, in combination with metronidazole it shows potential for treating mixed infections involving resistant Enterobacteriaceae and anaerobes...
  51. ncbi request reprint C. difficile infection (CDI) in a long-term acute care facility (LTAC)
    Ellie J C Goldstein
    R M Alden Research Laboratory, Culver City, CA 90230, USA
    Anaerobe 15:241-3. 2009
    ..Since scant information is available about the incidence and prevalence of CDI in Long-term acute care hospitals (LTACs), we therefore studied this at one local facility...
  52. doi request reprint Bacterial counts from five over-the-counter probiotics: are you getting what you paid for?
    Ellie J C Goldstein
    R M Alden Research Laboratory, Culver City, CA 90230, USA UCLA School of Medicine, Los Angeles, CA 90095, USA Electronic address
    Anaerobe 25:1-4. 2014
    ..2 × 10(9)-1.3 × 10(10) CFU/g. Lactinex(®), Align(®), Bio-K+(®), and Culturelle(®) had viable colony counts that were similar to those stated on the package. ..
  53. ncbi request reprint Anaerobic and aerobic bacteriology of the saliva and gingiva from 16 captive Komodo dragons (Varanus komodoensis): new implications for the "bacteria as venom" model
    Ellie J C Goldstein
    R M Alden Research Laboratory, Culver City, California 90230, USA
    J Zoo Wildl Med 44:262-72. 2013
    ..No virulent species were isolated. As with other carnivores, captive Komodo oral flora is simply reflective of the gut and skin flora of their recent meals and environment and is unlikely to cause rapid fatal infection...
  54. pmc Activity of Ceftaroline against Aerobic Gram-Positive and Gram-Negative Pathogens: Effect of Test Method Variability
    Diane M Citron
    R M Alden Research Laboratory, Culver City, CA 90230, USA
    ISRN Microbiol 2011:787290. 2011
    ..coli, K. pneumoniae, M. catarrhalis, H. influenzae, and streptococci, while an inoculum of 10(6) CFU/mL raised MICs of some E. coli, K. pneumoniae, and M. catarrhalis strains...
  55. pmc Periodontal bacteria in rabbit mandibular and maxillary abscesses
    Kerin L Tyrrell
    R M Alden Research Laboratory, UCLA Santa Monica Medical Center, Santa Monica, California 90404, USA
    J Clin Microbiol 40:1044-7. 2002
    ....
  56. ncbi request reprint 16S-23S rDNA internal transcribed spacer sequences for analysis of the phylogenetic relationships among species of the genus Fusobacterium
    Georg Conrads
    R M Alden Research Laboratory, Santa Monica University of California at Los Angeles Medical Center, Santa Monica 90404, USA
    Int J Syst Evol Microbiol 52:493-9. 2002
    ..Fusobacterium necrophorum subspp. necrophorum and funduliforme on the one hand, and Fusobacterium varium and Fusobacterium mortiferum on the other, were found to be very similar, even at the high-resolution ITS level...
  57. doi request reprint Reproducibility of broth microdilution and comparison to agar dilution for testing CB-183,315 against clinical isolates of Clostridium difficile
    Diane M Citron
    R M Alden Research Lab, Culver City, CA 90230, USA
    Diagn Microbiol Infect Dis 70:554-6. 2011
    ..Reproducibility was 100% within ± one 2-fold dilution for 10 strains tested; agreement was 90-95% within one 2-fold dilution with AD for 103 clinical isolates...
  58. ncbi request reprint Comparative in vitro activities of dalbavancin and seven comparator agents against 41 Staphylococcus species cultured from osteomyelitis infections and 18 VISA and hVISA strains
    Diane M Citron
    R M Alden Research Laboratory, Culver City, CA 90230 Electronic address
    Diagn Microbiol Infect Dis 79:438-40. 2014
    ..Dalbavancin is given once a week, making treatment of infections such as osteomyelitis potentially more convenient and thus could help reduce the rate of hospitalizations and outpatient costs. ..
  59. pmc Comparative in vitro activities of SMT19969, a new antimicrobial agent, against 162 strains from 35 less frequently recovered intestinal Clostridium species: implications for Clostridium difficile recurrence
    Ellie J C Goldstein
    R M Alden Research Laboratory, Culver City, California, USA
    Antimicrob Agents Chemother 58:1187-91. 2014
    ..SMT MICs ranged from 0.06 to >512 μg/ml and were not species related. SMT might have less impact on normal gut microbiota than other Clostridium difficile infection (CDI) antimicrobials. ..
  60. ncbi request reprint Update on the taxonomy and clinical aspects of the genus fusobacterium
    Diane M Citron
    R M Alden Research Laboratory, Santa Monica, CA, 90404, USA
    Clin Infect Dis 35:S22-7. 2002
    ..Fusobacterium prausnitzii is phylogenetically related to the Eubacterium-like organisms and will likely be reclassified in the future. The status of the remaining species is unchanged...
  61. pmc Desulfovibrio desulfuricans bacteremia and review of human Desulfovibrio infections
    Ellie J C Goldstein
    R M Alden Research Laboratory, St John s Hospital Health Center, Santa Monica, California 90404, USA
    J Clin Microbiol 41:2752-4. 2003
    ..vulgaris has been associated with intra-abdominal infections. In vitro studies suggest that empirical therapy with either imipenem or metronidazole should be considered...
  62. pmc In vitro activities of the des-fluoro(6) Quinolone BMS-284756 against aerobic and anaerobic pathogens isolated from skin and soft tissue animal and human bite wound infections
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica University of California, Los Angeles, Medical Center, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 46:866-70. 2002
    ..015 microg/ml. Fusobacterium russii and 6 of 11 Fusobacterium nucleatum isolates of animal bite origin were resistant, but isolates of human bite origin were susceptible, which suggests that they were of a different subspecies...