Thomas D Y Chung

Summary

Publications

  1. ncbi Assay format as a critical success factor for identification of novel inhibitor chemotypes of tissue-nonspecific alkaline phosphatase from high-throughput screening
    Thomas D Y Chung
    Conrad Prebys Center for Chemical Genomics, Sanford Burnham Medical Research Institute, La Jolla, CA 92037, USA
    Molecules 15:3010-37. 2010
  2. ncbi Inhibition of hematopoietic protein tyrosine phosphatase augments and prolongs ERK1/2 and p38 activation
    Eduard Sergienko
    Infectious and Inflammatory Disease Center, Sanford Burnham Medical Research Institute, La Jolla, California 92037, United States
    ACS Chem Biol 7:367-77. 2012

Detail Information

Publications2

  1. ncbi Assay format as a critical success factor for identification of novel inhibitor chemotypes of tissue-nonspecific alkaline phosphatase from high-throughput screening
    Thomas D Y Chung
    Conrad Prebys Center for Chemical Genomics, Sanford Burnham Medical Research Institute, La Jolla, CA 92037, USA
    Molecules 15:3010-37. 2010
    ..This illustrates the underappreciated impact of the underlying fundamental assay configuration on screening success, beyond mere signal generation and detection formats...
  2. ncbi Inhibition of hematopoietic protein tyrosine phosphatase augments and prolongs ERK1/2 and p38 activation
    Eduard Sergienko
    Infectious and Inflammatory Disease Center, Sanford Burnham Medical Research Institute, La Jolla, California 92037, United States
    ACS Chem Biol 7:367-77. 2012
    ..Our results warrant future studies with this probe compound that may establish HePTP as a new drug target for acute leukemic conditions...