M S Christian

Summary

Publications

  1. ncbi request reprint Teratogen update: evaluation of the reproductive and developmental risks of caffeine
    M S Christian
    Argus International and Argus Research Laboratories, Horsham, Pennsylvania 19044, USA
    Teratology 64:51-78. 2001
  2. ncbi request reprint Developmental toxicity studies of four fragrances in rats
    M S Christian
    Argus Research Laboratories Inc, Horsham, PA 19044, USA
    Toxicol Lett 111:169-74. 1999
  3. ncbi request reprint Introduction/overview: gender-based differences in pharmacologic and toxicologic responses
    M S Christian
    Primedica Argus Research Laboratories, Inc, Horsham, Pennsylvania 19044, USA
    Int J Toxicol 20:145-8. 2001
  4. ncbi request reprint Biodisposition of dibromoacetic acid (DBA) and bromodichloromethane (BDCM) administered to rats and rabbits in drinking water during range-finding reproduction and developmental toxicity studies
    M S Christian
    Argus Research Laboratories, Inc, Horsham, Pennsylvania 19044, USA
    Int J Toxicol 20:239-53. 2001
  5. ncbi request reprint Oral (drinking water) two-generation reproductive toxicity study of dibromoacetic acid (DBA) in rats
    M S Christian
    Argus Research Laboratories, Inc, Horsham, Pennsylvania 19044, USA
    Int J Toxicol 21:237-76. 2002
  6. ncbi request reprint Oral (drinking water) developmental toxicity studies of bromodichloromethane (BDCM) in rats and rabbits
    M S Christian
    Argus Research Laboratories, Inc, Horsham, Pennsylvania 19044, USA
    Int J Toxicol 20:225-37. 2001
  7. ncbi request reprint Lack of effects of nose-only inhalation exposure on testicular toxicity in male rats
    S J Rothenberg
    Primedica Argus, Horsham, Pennsylvania 19044, USA
    Toxicol Sci 53:127-34. 2000
  8. ncbi request reprint Developmental (embryo-fetal toxicity/teratogenicity) toxicity studies of synthetic crystalline lycopene in rats and rabbits
    M S Christian
    Argus International Inc 933 Horsham Road, Horsham, PA 19044, USA
    Food Chem Toxicol 41:773-83. 2003
  9. ncbi request reprint Lack of developmental neurotoxicity of MN rgp 120/HIV-1 administered subcutaneously to neonatal rats
    J L Bussiere
    Department of Toxicology, Genentech, Inc, South San Francisco, CA 94080, USA
    Toxicol Sci 48:90-9. 1999
  10. ncbi request reprint Embryo-fetal toxicity signals for 17alpha-hydroxyprogesterone caproate in high-risk pregnancies: a review of the non-clinical literature for embryo-fetal toxicity with progestins
    M S Christian
    Argus International, Horsham, PA 19044, USA
    J Matern Fetal Neonatal Med 20:89-112. 2007

Detail Information

Publications11

  1. ncbi request reprint Teratogen update: evaluation of the reproductive and developmental risks of caffeine
    M S Christian
    Argus International and Argus Research Laboratories, Horsham, Pennsylvania 19044, USA
    Teratology 64:51-78. 2001
    ..Proven human teratogens have an identifiable syndrome. The malformations described in the animal studies at very high doses fit the description of vascular disruptive types of malformations. (ABSTRACT TRUNCATED)..
  2. ncbi request reprint Developmental toxicity studies of four fragrances in rats
    M S Christian
    Argus Research Laboratories Inc, Horsham, PA 19044, USA
    Toxicol Lett 111:169-74. 1999
    ..The results of this study indicate that under conditions of normal use, the tested fragrances do not pose a risk to human conceptuses...
  3. ncbi request reprint Introduction/overview: gender-based differences in pharmacologic and toxicologic responses
    M S Christian
    Primedica Argus Research Laboratories, Inc, Horsham, Pennsylvania 19044, USA
    Int J Toxicol 20:145-8. 2001
    ....
  4. ncbi request reprint Biodisposition of dibromoacetic acid (DBA) and bromodichloromethane (BDCM) administered to rats and rabbits in drinking water during range-finding reproduction and developmental toxicity studies
    M S Christian
    Argus Research Laboratories, Inc, Horsham, Pennsylvania 19044, USA
    Int J Toxicol 20:239-53. 2001
    ....
  5. ncbi request reprint Oral (drinking water) two-generation reproductive toxicity study of dibromoacetic acid (DBA) in rats
    M S Christian
    Argus Research Laboratories, Inc, Horsham, Pennsylvania 19044, USA
    Int J Toxicol 21:237-76. 2002
    ..Based on the high multiples of human exposure required to produce effects in male rats, DBA should not be identified as a human reproductive or developmental risk...
  6. ncbi request reprint Oral (drinking water) developmental toxicity studies of bromodichloromethane (BDCM) in rats and rabbits
    M S Christian
    Argus Research Laboratories, Inc, Horsham, Pennsylvania 19044, USA
    Int J Toxicol 20:225-37. 2001
    ..3 mg/kg/day). These NOAELs are 56,250 and 69,120 times the human adult exposure level of 0.0008 mg/kg/day, respectively. Based on the results of these studies, BDCM should not be identified as a risk to development of human conceptuses...
  7. ncbi request reprint Lack of effects of nose-only inhalation exposure on testicular toxicity in male rats
    S J Rothenberg
    Primedica Argus, Horsham, Pennsylvania 19044, USA
    Toxicol Sci 53:127-34. 2000
    ..Thus, nose-only exposure for up to 2 h per day for a total of 42 days did not cause adverse effects on the reproductive organs, fertility, or reproductive performance of male rats under the conditions of this study...
  8. ncbi request reprint Developmental (embryo-fetal toxicity/teratogenicity) toxicity studies of synthetic crystalline lycopene in rats and rabbits
    M S Christian
    Argus International Inc 933 Horsham Road, Horsham, PA 19044, USA
    Food Chem Toxicol 41:773-83. 2003
    ..Neither Lycopene 10 CWD nor LycoVit 10% caused direct maternal or developmental toxicity in rats or rabbits at dosages as high as 3000 or 2000 mg/kg/day, respectively...
  9. ncbi request reprint Lack of developmental neurotoxicity of MN rgp 120/HIV-1 administered subcutaneously to neonatal rats
    J L Bussiere
    Department of Toxicology, Genentech, Inc, South San Francisco, CA 94080, USA
    Toxicol Sci 48:90-9. 1999
    ..Thus, MN rgp120/HIV-1 alone or formulated as a vaccine does not cause neurotoxicity or developmental toxicity in neonatal rats after exposure in utero and/or during the neonatal period...
  10. ncbi request reprint Embryo-fetal toxicity signals for 17alpha-hydroxyprogesterone caproate in high-risk pregnancies: a review of the non-clinical literature for embryo-fetal toxicity with progestins
    M S Christian
    Argus International, Horsham, PA 19044, USA
    J Matern Fetal Neonatal Med 20:89-112. 2007
    ....
  11. ncbi request reprint Oral (drinking water) two-generation reproductive toxicity study of bromodichloromethane (BDCM) in rats
    M S Christian
    Argus Research Laboratories, Inc, Horsham, Pennsylvania, USA
    Int J Toxicol 21:115-46. 2002
    ..5 to 109.0 mg/kg/day), or 36,875 to 136,250 times the human adult exposure level. Regardless, these data indicate that BDCM should not be identified as a risk to human reproductive performance or development of human conceptuses...