Jung Kyoon Choi

Summary

Publications

  1. pmc Identification of DNA methylation changes associated with human gastric cancer
    Jung Hoon Park
    Department of Biochemistry, College of Life Science and Technology, Yonsei University, Seoul, Korea
    BMC Med Genomics 4:82. 2011
  2. pmc Nucleosome deposition and DNA methylation at coding region boundaries
    Jung Kyoon Choi
    Department of Biochemistry, College of Life Science and Technology, Yonsei University, 134 Sinchon dong, Seodaemun gu, Seoul, Korea
    Genome Biol 10:R89. 2009
  3. doi request reprint Systems biology and epigenetic gene regulation
    J K Choi
    KAIST, Department of Bio and Brain Engineering, Daejeon, Republic of Korea
    IET Syst Biol 4:289-95. 2010
  4. pmc Environmental effects on gene expression phenotype have regional biases in the human genome
    Jung Kyoon Choi
    Korean BioInformation Center, KRIBB, Yooseong goo, Daejeon, 305 806, Korea
    Genetics 175:1607-13. 2007
  5. pmc Contrasting chromatin organization of CpG islands and exons in the human genome
    Jung Kyoon Choi
    Department of Biology and Brain Engineering, KAIST, 335 Gwahak ro, Daejeon 305 701, Republic of Korea
    Genome Biol 11:R70. 2010
  6. ncbi request reprint Differential coexpression analysis using microarray data and its application to human cancer
    Jung Kyoon Choi
    National Genome Information Center, Korea Research Institute of Bioscience and Biotechnology, 52 Ueun dong, Yuseong Gu, Daejeon, Korea
    Bioinformatics 21:4348-55. 2005
  7. pmc Genetic landscape of open chromatin in yeast
    Kibaick Lee
    Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea
    PLoS Genet 9:e1003229. 2013
  8. ncbi request reprint Integrative analysis of multiple gene expression profiles applied to liver cancer study
    Jung Kyoon Choi
    National Genome Information Center, Korea Research Institute of Biosciences and Biotechnology, Daejeon, Republic of Korea
    FEBS Lett 565:93-100. 2004
  9. doi request reprint Controlling transcriptional programs for cellular adaptation by chromatin regulation
    Sang Cheol Kim
    Korean BioInformation Center, KRIBB, Daejeon 305 701, Korea
    Mol Biosyst 7:1713-9. 2011
  10. ncbi request reprint TO-GO: a Java-based Gene Ontology navigation environment
    Ungsik Yu
    National Genome Information Center, KRIBB, Oun 52, Yusong, Daejeon 305 333, Korea
    Bioinformatics 21:3580-1. 2005

Collaborators

  • Sangsoo Kim
  • Ungsik Yu
  • Dongsup Kim
  • Inkyung Jung
  • Byungwook Lee
  • Jungmin Seo
  • Kibaick Lee
  • Kwoneel Kim
  • Heun Sik Lee
  • Jung Hoon Park
  • Ho Bum Kang
  • Sanghyuk Lee
  • Dong Yeop Chang
  • Jongbum Kwon
  • Gireesh K Bogu
  • Eui Cheol Shin
  • Nur Lina Mohd Salleh
  • Jin Sung Kim
  • Kartiki Vasant Desai
  • Eun Suk Kang
  • Jung Kyu Kim
  • Jae Ho Lee
  • Hye Jin Shon
  • Jinah Park
  • Min Gyun Bae
  • Dong Yoon Park
  • Young Joon Kim
  • Han Kwang Yang
  • Tae You Kim
  • Young Gun Lee
  • Jae Bum Bae
  • Jaemyun Lyu

Detail Information

Publications14

  1. pmc Identification of DNA methylation changes associated with human gastric cancer
    Jung Hoon Park
    Department of Biochemistry, College of Life Science and Technology, Yonsei University, Seoul, Korea
    BMC Med Genomics 4:82. 2011
    ..Epigenetic alteration of gene expression is a common event in human cancer. DNA methylation is a well-known epigenetic process, but verifying the exact nature of epigenetic changes associated with cancer remains difficult...
  2. pmc Nucleosome deposition and DNA methylation at coding region boundaries
    Jung Kyoon Choi
    Department of Biochemistry, College of Life Science and Technology, Yonsei University, 134 Sinchon dong, Seodaemun gu, Seoul, Korea
    Genome Biol 10:R89. 2009
    ..Nucleosome deposition downstream of transcription initiation and DNA methylation in the gene body suggest that control of transcription elongation is a key aspect of epigenetic regulation...
  3. doi request reprint Systems biology and epigenetic gene regulation
    J K Choi
    KAIST, Department of Bio and Brain Engineering, Daejeon, Republic of Korea
    IET Syst Biol 4:289-95. 2010
    ....
  4. pmc Environmental effects on gene expression phenotype have regional biases in the human genome
    Jung Kyoon Choi
    Korean BioInformation Center, KRIBB, Yooseong goo, Daejeon, 305 806, Korea
    Genetics 175:1607-13. 2007
    ....
  5. pmc Contrasting chromatin organization of CpG islands and exons in the human genome
    Jung Kyoon Choi
    Department of Biology and Brain Engineering, KAIST, 335 Gwahak ro, Daejeon 305 701, Republic of Korea
    Genome Biol 11:R70. 2010
    ..Intragenic nucleosomes and their modifications have been recently associated with RNA splicing. Because the function of intragenic DNA methylation remains unclear, I explored the possibility of its involvement in splicing regulation...
  6. ncbi request reprint Differential coexpression analysis using microarray data and its application to human cancer
    Jung Kyoon Choi
    National Genome Information Center, Korea Research Institute of Bioscience and Biotechnology, 52 Ueun dong, Yuseong Gu, Daejeon, Korea
    Bioinformatics 21:4348-55. 2005
    ..However, alteration in coexpression relationships has not been studied. Here we introduce a model for finding differential coexpression from microarrays and test its biological validity with respect to cancer...
  7. pmc Genetic landscape of open chromatin in yeast
    Kibaick Lee
    Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea
    PLoS Genet 9:e1003229. 2013
    ..Our findings provide a global quantitative picture of the genetic architecture of chromatin regulation...
  8. ncbi request reprint Integrative analysis of multiple gene expression profiles applied to liver cancer study
    Jung Kyoon Choi
    National Genome Information Center, Korea Research Institute of Biosciences and Biotechnology, Daejeon, Republic of Korea
    FEBS Lett 565:93-100. 2004
    ..Our findings support the use of meta-analysis for a variety of microarray data beyond the scope of this specific application...
  9. doi request reprint Controlling transcriptional programs for cellular adaptation by chromatin regulation
    Sang Cheol Kim
    Korean BioInformation Center, KRIBB, Daejeon 305 701, Korea
    Mol Biosyst 7:1713-9. 2011
    ..These regulatory mechanisms can also contribute to evolutionary adaptation...
  10. ncbi request reprint TO-GO: a Java-based Gene Ontology navigation environment
    Ungsik Yu
    National Genome Information Center, KRIBB, Oun 52, Yusong, Daejeon 305 333, Korea
    Bioinformatics 21:3580-1. 2005
    ..A copy/paste function is also implemented in order to facilitate data exchange between applications...
  11. pmc Impact of transcriptional properties on essentiality and evolutionary rate
    Jung Kyoon Choi
    Korean BioInformation Center, KRIBB, Daejeon 305 806, Korea
    Genetics 175:199-206. 2007
    ..Transcriptional variability, rather than transcriptional activity, might be a common indicator of essentiality and evolutionary rate, contributing to the correlation between the two variables...
  12. ncbi request reprint Genome-wide reorganization of histone H2AX toward particular fragile sites on cell activation
    Jungmin Seo
    Research Institute of Bioinformatics, Omicsis, Inc, Daejeon 305 333, Korea, Department of Bio and Brain Engineering, KAIST, Daejeon 305 701, Korea, Graduate School of Medical Science and Engineering, KAIST, Daejeon 305 701, Korea, Medical Genomics Research Center, KRIBB, Daejeon 305 333, Korea and Department of Life Science, Ewha Womans University, Seoul 120 750, Korea
    Nucleic Acids Res . 2013
    ..Our findings suggest that active DNA replication is accompanied with the specific localization of H2AX and INO80 for efficient damage repair or replication-fork stabilization in actively transcribed regions...
  13. pmc Genome-wide profiles of H2AX and γ-H2AX differentiate endogenous and exogenous DNA damage hotspots in human cells
    Jungmin Seo
    Research Institute of Bioinformatics, Omicsis, Inc, BVC, KRIBB, Daejeon 305 333, Korea
    Nucleic Acids Res 40:5965-74. 2012
    ..Sub-telomeres were less responsive to external DNA damage than to endogenous stress. Our findings provide insight into DNA repair programs of cancer and may have implications for cancer therapy...
  14. ncbi request reprint Combining multiple microarray studies and modeling interstudy variation
    Jung Kyoon Choi
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 371 1 Guseong dong Yuseong gu, Daejeon 305 701, Korea
    Bioinformatics 19:i84-90. 2003
    ..We also developed an alternative modeling procedure based on a Bayesian approach, which would offer flexibility and robustness compared to the classical procedure...