Ki Choon Choi



  1. Kuppusamy P, Soundharrajan I, Kim D, Hwang I, Choi K. 4-hydroxy-3-methoxy cinnamic acid accelerate myoblasts differentiation on C2C12 mouse skeletal muscle cells via AKT and ERK 1/2 activation. Phytomedicine. 2019;:152873 pubmed publisher
    ..Therefore, this study suggests that the natural phenolic compound HMCA has a potent function in muscle cell proliferation, differentiation, and development. ..
  2. Vijayakumar M, Ilavenil S, Kim D, Arasu M, Priya K, Choi K. In-vitro assessment of the probiotic potential of Lactobacillus plantarum KCC-24 isolated from Italian rye-grass (Lolium multiflorum) forage. Anaerobe. 2015;32:90-97 pubmed publisher
    ..In conclusion, the isolated L. plantarum KCC-24 exhibited several characteristics to prove it's excellent as a potential probiotic candidate for developing quality food for ruminant animals and human. ..
  3. Soundharrajan I, Kim D, Srisesharam S, Kuppusamy P, Sivanesan R, Choi K. Limonene promotes osteoblast differentiation and 2-deoxy-d-glucose uptake through p38MAPK and Akt signaling pathways in C2C12 skeletal muscle cells. Phytomedicine. 2018;45:41-48 pubmed publisher
  4. Ilavenil S, Kim D, Jeong Y, Arasu M, Vijayakumar M, Prabhu P, et al. Trigonelline protects the cardiocyte from hydrogen peroxide induced apoptosis in H9c2 cells. Asian Pac J Trop Med. 2015;8:263-8 pubmed publisher
    ..Therefore, we suggest the trigonelline could be useful for treatment of oxidative stress mediated cardiovascular diseases in future. ..
  5. Ilavenil S, Kim D, Valan Arasu M, Srigopalram S, Sivanesan R, Choi K. Phenyllactic Acid from Lactobacillus plantarum PromotesAdipogenic Activity in 3T3-L1 Adipocyte via Up-Regulationof PPAR-γ2. Molecules. 2015;20:15359-73 pubmed publisher
    ..49 ± 0.20 mM). Hence, we conclude that PLA treatment enhances adipocyte differentiation and glucose uptake via activation of PPAR-γ2, and PLA may thus be the potential candidate for preventing Type 2 Diabetes Mellitus (T2DM). ..
  6. Vedarethinam V, Dhanaraj K, Ilavenil S, Arasu M, Choi K, Al Dhabi N, et al. Antitumor Effect of the Mannich Base(1,3-bis-((3-Hydroxynaphthalen-2-yl)phenylmethyl)urea) on Hepatocellular Carcinoma. Molecules. 2016;21: pubmed publisher
    ..In this study, the molecular and pre-clinical results obtained by treatment of DEN-induced rats with 1,3-BPMU suggested that 1,3-BPMU might be considered as an antitumor compound in the future. ..
  7. Ilavenil S, Kim D, Srigopalram S, Arasu M, Lee K, Lee J, et al. Potential Application of p-Coumaric Acid on Differentiation of C2C12 Skeletal Muscle and 3T3-L1 Preadipocytes-An in Vitro and in Silico Approach. Molecules. 2016;21: pubmed publisher
    ..90 contact distances. These data indicated that CA suppressed skeletal muscle and preadipocytes differentiation through downregulation of the main transcriptional factors and their downstream targets. ..
  8. Ilavenil S, Kim D, Vijayakumar M, Srigopalram S, Roh S, Arasu M, et al. Potential role of marine algae extract on 3T3-L1 cell proliferation and differentiation: an in vitro approach. Biol Res. 2016;49:38 pubmed publisher
    ..The present research findings confirmed that the EECV effectively modulates the lipid accumulation and differentiation in 3T3-L1 cells through AMPK-? mediated signalling pathway. ..
  9. Choi K, Cho S, Kook S, Chun S, Bhattarai G, Poudel S, et al. Intestinal anti-inflammatory activity of the seeds of Raphanus sativus L. in experimental ulcerative colitis models. J Ethnopharmacol. 2016;179:55-65 pubmed publisher
    ..The current findings show that RWE ameliorates intestinal oxidative and inflammatory damages in DSS and TNBS models of rat colitis, suggesting its beneficial use for the treatment of intestinal inflammatory disorders. ..

More Information


  1. Ilavenil S, Al Dhabi N, Srigopalram S, Ock Kim Y, Agastian P, Baru R, et al. Acetaminophen Induced Hepatotoxicity in Wistar Rats--A Proteomic Approach. Molecules. 2016;21:161 pubmed publisher
    ..Several other proteins were identified as a first step in developing an in-house rodent liver toxicoproteomics database. ..
  2. Ilavenil S, Arasu M, Lee J, Kim D, Vijayakumar M, Lee K, et al. Positive regulations of adipogenesis by Italian ryegrass [Lolium multiflorum] in 3T3-L1 cells. BMC Biotechnol. 2014;14:54 pubmed publisher
    ..These findings suggest that CELM stimulates adipogenesis via activating the PPAR?-mediated signaling pathway in adipocyte which could be useful for the development of meat quality in animals. ..