Research Topics

Cheng Le Zhuang

Summary

Country: China

Publications

  1. Chen X, Li B, Ma B, Zhang X, Chen W, Lu L, et al. Sarcopenia is an effective prognostic indicator of postoperative outcomes in laparoscopic-assisted gastrectomy. Eur J Surg Oncol. 2019;: pubmed publisher
    ..274-5.944; P = 0.010) were independent risk factors for short-term postoperative complications. Sarcopenia is an independent clinical predictor of short-term postoperative complications after laparoscopic-assisted gastrectomy. ..
  2. Huang D, Fan S, Chen X, Yan X, Zhang X, Ma B, et al. Nrf2 deficiency exacerbates frailty and sarcopenia by impairing skeletal muscle mitochondrial biogenesis and dynamics in an age-dependent manner. Exp Gerontol. 2019;119:61-73 pubmed publisher
    ..Nrf2 deficiency exacerbated frailty and sarcopenia during aging, at least partially by impairing skeletal muscle mitochondrial biogenesis and dynamics in an age-dependent manner. ..
  3. Ma B, Chen X, Fan S, Zhang F, Huang D, Li B, et al. Impact of sarcopenia on clinical outcomes after radical gastrectomy for patients without nutritional risk. Nutrition. 2018;61:61-66 pubmed publisher
    ..Preoperative assessment and management of sarcopenia should be helpful for improving clinical outcomes for patients without nutritional risk. ..
  4. Chen F, Zhang F, Zhou X, Shen X, Yu Z, Zhuang C. Role of frailty and nutritional status in predicting complications following total gastrectomy with D2 lymphadenectomy in patients with gastric cancer: a prospective study. Langenbecks Arch Surg. 2016;401:813-22 pubmed publisher
    ..Frailty should be integrated into preoperative risk assessment and may have implications in preoperative decisionmaking. ..
  5. Huang D, Chen X, Chen X, Wang S, Shen X, Chen X, et al. Sarcopenia predicts 1-year mortality in elderly patients undergoing curative gastrectomy for gastric cancer: a prospective study. J Cancer Res Clin Oncol. 2016;142:2347-56 pubmed publisher
    ..Sarcopenia is predictive of 1-year mortality in elderly patients undergoing gastric cancer surgery. The measurement of muscle function is important for sarcopenia as a preoperative assessment tool. ..
  6. Lou N, Chi C, Chen X, Zhou C, Wang S, Zhuang C, et al. Sarcopenia in overweight and obese patients is a predictive factor for postoperative complication in gastric cancer: A prospective study. Eur J Surg Oncol. 2017;43:188-195 pubmed publisher
    ..002). Sarcopenia is an independent predictor of postoperative complications in overweight or obese patients with gastric cancer after radical gastrectomy. ..
  7. Huang D, Zhou C, Wang S, Mao S, Zhou X, Lou N, et al. Impact of different sarcopenia stages on the postoperative outcomes after radical gastrectomy for gastric cancer. Surgery. 2017;161:680-693 pubmed publisher
    ..The 3 sarcopenia stages independently influence medical but not surgical complications. Recognizing sarcopenia stages is important for preoperative risk stratification. ..
  8. Zhou C, Zhang F, Zhang F, Yu Z, Chen X, Shen X, et al. Sarcopenia: a new predictor of postoperative complications for elderly gastric cancer patients who underwent radical gastrectomy. J Surg Res. 2017;211:137-146 pubmed publisher
    ..Sarcopenia, presented as a new geriatric assessment factor, was a strong and independent risk factor for postoperative complications of elderly patients with gastric cancer. ..
  9. Huang D, Ji Y, Zhou D, Li B, Wang S, Chen X, et al. Effect of surgery-induced acute muscle wasting on postoperative outcomes and quality of life. J Surg Res. 2017;218:58-66 pubmed publisher
    ..Clinically relevant muscle wasting was associated with a poorer QOL and short-term outcomes after surgery. ..

More Information

Publications10

  1. Wang S, Ma L, Chen X, Zhou D, Li B, Huang D, et al. Impact of visceral fat on surgical complications and long-term survival of patients with gastric cancer after radical gastrectomy. Eur J Clin Nutr. 2018;72:436-445 pubmed publisher
    ..Increased VFA independently predicts surgical complications in patients after gastrectomy. However, VFA is not a prognostic biomarker of OS or DFS in patients with gastric cancer. ..