Xiao Mei Zhu
Zhu X, Yao Y, Liang H, Xu C, Dong N, Yu Y, et al
. High mobility group box-1 protein regulate immunosuppression of regulatory T cells through toll-like receptor 4. Cytokine. 2011;54:296-304 pubmed publisher
..Our data suggest that HMGB1 has the ability to directly modulate the suppressive capacity of CD4(+)CD25(+)Tregs, and TLR4 might be a potential receptor essential for the negative effect of HMGB1 on CD4(+)CD25(+)Tregs activity. ..