Youxin Zhou

Summary

Country: China

Publications

  1. ncbi request reprint Antiangiogenic effect of celastrol on the growth of human glioma: an in vitro and in vivo study
    You xin Zhou
    Department of Neurosurgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
    Chin Med J (Engl) 122:1666-73. 2009
  2. pmc Boron neutron capture therapy induces cell cycle arrest and cell apoptosis of glioma stem/progenitor cells in vitro
    Ting Sun
    Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
    Radiat Oncol 8:195. 2013
  3. ncbi request reprint [Establishment of a new human glioma cell line and analysis of its biological characteristics]
    Guilin Chen
    Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou 215006, China
    Zhonghua Zhong Liu Za Zhi 37:84-90. 2015
  4. doi request reprint Selective uptake of boronophenylalanine by glioma stem/progenitor cells
    Ting Sun
    Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
    Appl Radiat Isot 70:1512-8. 2012
  5. doi request reprint Comparative analysis of pathology and boronophenylalanine uptake in experimental orthotopic and heterotopic amelanotic melanoma
    Ting Sun
    Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
    Melanoma Res 24:315-21. 2014
  6. doi request reprint Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression
    Yulun Huang
    Department of Neurosurgery, The First Affiliated Hospital of Suzhou University, Suzhou, China
    Cancer Lett 264:101-6. 2008
  7. pmc Analysis of the expression profile of Dickkopf-1 gene in human glioma and the association with tumor malignancy
    Youxin Zhou
    Department of Neurosurgery, The First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu, China
    J Exp Clin Cancer Res 29:138. 2010
  8. doi request reprint Preparation, characterization, and assessment of the antiglioma effects of liposomal celastrol
    Yulun Huang
    Department of Neurosurgery, First Affiliated Hospital of Soochow University, Suzhou, China
    Anticancer Drugs 23:515-24. 2012
  9. pmc Identification of a NFKBIA polymorphism associated with lower NFKBIA protein levels and poor survival outcomes in patients with glioblastoma multiforme
    Zhaohui Zhao
    Department of Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P R China
    Int J Mol Med 34:1233-40. 2014
  10. pmc Biological characteristics of a new human glioma cell line transformed into A2B5(+) stem cells
    Yanyan Li
    Department of Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou, Jiangsu, China
    Mol Cancer 14:75. 2015

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Antiangiogenic effect of celastrol on the growth of human glioma: an in vitro and in vivo study
    You xin Zhou
    Department of Neurosurgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
    Chin Med J (Engl) 122:1666-73. 2009
    ..The present study aims to demonstrate that celastrol has potent anticancer activity against glioma in vitro and in vivo...
  2. pmc Boron neutron capture therapy induces cell cycle arrest and cell apoptosis of glioma stem/progenitor cells in vitro
    Ting Sun
    Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
    Radiat Oncol 8:195. 2013
    ..An almost inevitable glioma recurrence is due to the persistence of these cells. The high linear energy transfer associated with boron neutron capture therapy (BNCT) could kill quiescent and proliferative cells...
  3. ncbi request reprint [Establishment of a new human glioma cell line and analysis of its biological characteristics]
    Guilin Chen
    Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou 215006, China
    Zhonghua Zhong Liu Za Zhi 37:84-90. 2015
    ..To establish a new glioma cell line and analyze its biological characteristics, and to provide a useful cellular tool with new features for cancer research...
  4. doi request reprint Selective uptake of boronophenylalanine by glioma stem/progenitor cells
    Ting Sun
    Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
    Appl Radiat Isot 70:1512-8. 2012
    ..However, boron biodistribution was not statistically significantly different in mice with xenografts...
  5. doi request reprint Comparative analysis of pathology and boronophenylalanine uptake in experimental orthotopic and heterotopic amelanotic melanoma
    Ting Sun
    Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
    Melanoma Res 24:315-21. 2014
    ....
  6. doi request reprint Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression
    Yulun Huang
    Department of Neurosurgery, The First Affiliated Hospital of Suzhou University, Suzhou, China
    Cancer Lett 264:101-6. 2008
    ..These findings suggest that celastrol have potential to be used as an antiangiogenesis drug through its role in suppressing VEGF receptors expression that might consequently reduce the signal transduction between VEGF and VEGFR...
  7. pmc Analysis of the expression profile of Dickkopf-1 gene in human glioma and the association with tumor malignancy
    Youxin Zhou
    Department of Neurosurgery, The First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu, China
    J Exp Clin Cancer Res 29:138. 2010
    ..Dickkopf-1 (DKK-1) is a secreted protein that acts as a potent inhibitor of the Wnt pathway. The aim of this study was to examine the expression profile of DKK-1 gene in human glioma and its association with tumor malignancy...
  8. doi request reprint Preparation, characterization, and assessment of the antiglioma effects of liposomal celastrol
    Yulun Huang
    Department of Neurosurgery, First Affiliated Hospital of Soochow University, Suzhou, China
    Anticancer Drugs 23:515-24. 2012
    ..Our findings suggest that liposomal celastrol should be further investigated in the clinical setting...
  9. pmc Identification of a NFKBIA polymorphism associated with lower NFKBIA protein levels and poor survival outcomes in patients with glioblastoma multiforme
    Zhaohui Zhao
    Department of Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P R China
    Int J Mol Med 34:1233-40. 2014
    ..Hence, by identifying rs1957106 as a novel SNP in NFKBIA in glioblastoma patients, we provide a new platform for further investigating the function of NFKBIA in the pathobiology of glioblastoma. ..
  10. pmc Biological characteristics of a new human glioma cell line transformed into A2B5(+) stem cells
    Yanyan Li
    Department of Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou, Jiangsu, China
    Mol Cancer 14:75. 2015
    ..The new glioma cell line SHG-139 was established and its phenotype, tumorigenicity, pathological characteristics, derived stem cells SHG139S were studied...
  11. pmc MicroRNA-184 inhibits cell proliferation and invasion, and specifically targets TNFAIP2 in Glioma
    Zhe Cheng
    Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou, Jiangsu, 215006, Peoples Republic of China
    J Exp Clin Cancer Res 34:27. 2015
    ..This study aimed to determine the functions of miR-184 in glioma and the mechanisms of miRNA-184-TNFAIP2 mediated glioma progression...
  12. pmc Elevated expression of Dickkopf-1 increases the sensitivity of human glioma cell line SHG44 to BCNU
    Youxin Zhou
    Department of Neurosurgery, The First Affiliated Hospital of Soochow University, Suzhou, China
    J Exp Clin Cancer Res 29:131. 2010
    ..The aim of this study is to further examine the function of DKK-1 in glioma cells...
  13. pmc The Zfx gene is expressed in human gliomas and is important in the proliferation and apoptosis of the human malignant glioma cell line U251
    Youxin Zhou
    Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou 215006, China
    J Exp Clin Cancer Res 30:114. 2011
    ..However, the importance of Zfx in human glioma is largely unknown. In the present study, we examined the role of Zfx in human glioma...