Wenhua Zhou

Summary

Country: China

Publications

  1. ncbi request reprint Low dose of heroin inhibits drug-seeking elicited by cues after prolonged withdrawal from heroin self-administration in rats
    Wenhua Zhou
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, 42 Xibei Str, Ningbo 315010, PR China
    Neuroreport 15:727-30. 2004
  2. pmc Assessment of attitudes towards methadone maintenance treatment between heroin users at a compulsory detoxification centre and methadone maintenance clinic in Ningbo, China
    Yu Liu
    Ningbo University School of Medicine, 818 Fenghua Street, Jiangbei District, Ningbo, Zhejiang, China
    Subst Abuse Treat Prev Policy 8:29. 2013
  3. doi request reprint Effects of training and withdrawal periods on heroin seeking induced by conditioned cue in an animal of model of relapse
    Wenhua Zhou
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Str, Ningbo, 315010, People s Republic of China
    Psychopharmacology (Berl) 203:677-84. 2009
  4. pmc Role of acetylcholine transmission in nucleus accumbens and ventral tegmental area in heroin-seeking induced by conditioned cues
    W Zhou
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Str, Ningbo 315010, PR China
    Neuroscience 144:1209-18. 2007
  5. ncbi request reprint The dissociation of heroin-seeking patterns induced by contextual, discriminative, or discrete conditioned cues in a model of relapse to heroin in rats
    Wenhua Zhou
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, People s Republic of China
    Psychopharmacology (Berl) 181:197-206. 2005
  6. doi request reprint Galantamine attenuates the heroin seeking behaviors induced by cues after prolonged withdrawal in rats
    Huifen Liu
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Str, Ningbo 315010, PR China
    Neuropharmacology 62:2515-21. 2012
  7. doi request reprint DBS of nucleus accumbens on heroin seeking behaviors in self-administering rats
    Liemei Guo
    Department of Neurosurgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
    Drug Alcohol Depend 129:70-81. 2013
  8. doi request reprint Low dose risperidone attenuates cue-induced but not heroin-induced reinstatement of heroin seeking in an animal model of relapse
    Miaojun Lai
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, Ningbo, P R China
    Int J Neuropsychopharmacol 16:1569-75. 2013
  9. ncbi request reprint Increased c-Fos expression in the medial part of the lateral habenula during cue-evoked heroin-seeking in rats
    Fuqiang Zhang
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, 42 Xibeijie St, Ningbo 315010, PR China
    Neurosci Lett 386:133-7. 2005
  10. doi request reprint Vagus nerve stimulation inhibits heroin-seeking behavior induced by heroin priming or heroin-associated cues in rats
    Huifen Liu
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Str, Ningbo 315010, Zhejiang Province, PR China
    Neurosci Lett 494:70-4. 2011

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Low dose of heroin inhibits drug-seeking elicited by cues after prolonged withdrawal from heroin self-administration in rats
    Wenhua Zhou
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, 42 Xibei Str, Ningbo 315010, PR China
    Neuroreport 15:727-30. 2004
    ..The results suggest that prolonged withdrawal may increase the risk of relapse to heroin seeking...
  2. pmc Assessment of attitudes towards methadone maintenance treatment between heroin users at a compulsory detoxification centre and methadone maintenance clinic in Ningbo, China
    Yu Liu
    Ningbo University School of Medicine, 818 Fenghua Street, Jiangbei District, Ningbo, Zhejiang, China
    Subst Abuse Treat Prev Policy 8:29. 2013
    ..Therefore, better understanding of the attitudes and beliefs of people in the Compulsory Detoxification Centres can help to provide more adequate response to opioid dependence...
  3. doi request reprint Effects of training and withdrawal periods on heroin seeking induced by conditioned cue in an animal of model of relapse
    Wenhua Zhou
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Str, Ningbo, 315010, People s Republic of China
    Psychopharmacology (Berl) 203:677-84. 2009
    ..A high incidence of relapse can be triggered by exposure to conditioned cues previously associated with heroin. Extended access to drug and withdrawal are thought to affect the motivation for drug seeking...
  4. pmc Role of acetylcholine transmission in nucleus accumbens and ventral tegmental area in heroin-seeking induced by conditioned cues
    W Zhou
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Str, Ningbo 315010, PR China
    Neuroscience 144:1209-18. 2007
    ..Moreover, cue-induced reinstatement was inhibited by physostigmine in the NAc and potentiated by cholinergic stimulation in the VTA...
  5. ncbi request reprint The dissociation of heroin-seeking patterns induced by contextual, discriminative, or discrete conditioned cues in a model of relapse to heroin in rats
    Wenhua Zhou
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, People s Republic of China
    Psychopharmacology (Berl) 181:197-206. 2005
    ..The role of heroin-related stimuli in motivating the resumption of heroin use is not fully understood...
  6. doi request reprint Galantamine attenuates the heroin seeking behaviors induced by cues after prolonged withdrawal in rats
    Huifen Liu
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Str, Ningbo 315010, PR China
    Neuropharmacology 62:2515-21. 2012
    ..The present studies investigated the effect of systemic or intra- LDT administration of galantamine, an inhibitor of acetylcholinesterase, on heroin-seeking induced by cues...
  7. doi request reprint DBS of nucleus accumbens on heroin seeking behaviors in self-administering rats
    Liemei Guo
    Department of Neurosurgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
    Drug Alcohol Depend 129:70-81. 2013
    ..Deep brain stimulation (DBS), a less invasive, reversible and adjustable process of neuromodulation, was adopted to attenuate relapses in studies of drug addiction...
  8. doi request reprint Low dose risperidone attenuates cue-induced but not heroin-induced reinstatement of heroin seeking in an animal model of relapse
    Miaojun Lai
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, Ningbo, P R China
    Int J Neuropsychopharmacol 16:1569-75. 2013
    ..These data demonstrate that acute treatment with low-dose risperidone inhibits conditioned cue-induced heroin seeking and risperidone may be an adjunctive therapy for the treatment of heroin addiction. ..
  9. ncbi request reprint Increased c-Fos expression in the medial part of the lateral habenula during cue-evoked heroin-seeking in rats
    Fuqiang Zhang
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, 42 Xibeijie St, Ningbo 315010, PR China
    Neurosci Lett 386:133-7. 2005
    ..This observation suggests the involvement of the LHb in mediating drug cue-induced heroin-seeking behavior after abstinence from self-administration of heroin...
  10. doi request reprint Vagus nerve stimulation inhibits heroin-seeking behavior induced by heroin priming or heroin-associated cues in rats
    Huifen Liu
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Str, Ningbo 315010, Zhejiang Province, PR China
    Neurosci Lett 494:70-4. 2011
    ..The data suggest that vagus nerve stimulation may inhibit heroin- or heroin cue-induced relapse, possibly by regulation of the expression of Fos and CREB in nucleus accumbens...
  11. ncbi request reprint Motivation of heroin-seeking elicited by drug-associated cues is related to total amount of heroin exposure during self-administration in rats
    Fuqiang Zhang
    Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, 42 Xibeijie Street, Ningbo 315010, P R China
    Pharmacol Biochem Behav 79:291-8. 2004
    ..025 mg/kg. The results suggested that an increased motivation to seek heroin induced by drug-related cues is associated with the total amount of heroin intake...
  12. doi request reprint The effects of rearing condition on methamphetamine self-administration and cue-induced drug seeking
    Xiuyi Lü
    Ningbo University School of Medicine, PR China
    Drug Alcohol Depend 124:288-98. 2012
    ..Little is known about the effect of different rearing conditions on the effects of methamphetamine and whether the introduction of enriched rearing conditions at different stages of development could produce different behavioral outcomes...
  13. doi request reprint Positive association between--1021TT genotype of dopamine beta hydroxylase gene and progressive behavior of injection heroin users
    Xiaohu Xie
    Laboratory of Behavioral Neuroscience, Ningbo University, Ningbo, Zhejiang 315010, China
    Neurosci Lett 541:258-62. 2013
    ..In conclusion, our results support -1021TT genotype may be implicated with a more progressive nature of heroin addiction, although DBH -1021C/T is unlikely to be involved in the risk of heroin addiction...
  14. doi request reprint Temporal changes of smoking status and motivation among Chinese heroin-dependent, methadone-maintained smokers
    Longhui Li
    Ningbo Addiction Research and Treatment Center, Ningbo University, PR China
    Addict Behav 35:861-5. 2010
    ..It remains undetermined whether smoking status and motivation would be differentially affected by heroin and methadone administration...
  15. pmc Attitudes and knowledge about naloxone and overdose prevention among detained drug users in Ningbo, China
    Yu Liu
    School of Medicine, Ningbo University, 818 Fenghua Street, Jiangbei District, Ningbo, Zhejiang 315211, China
    Subst Abuse Treat Prev Policy 7:6. 2012
    ..In addition, there has been no effort to integrate naloxone information and distribution into pre-release services for drug users detained in isolated compulsory detoxification facilities in China...
  16. doi request reprint NF-E2-related factor 2 activation in PC12 cells: its protective role in manganese-induced damage
    Huangyuan Li
    Department of Occupational and Environmental Health, Research Unit for Toxicology and Chemical Safety Assessment, Institution of Environmental and Health, Major Subject of Environment and Health of Fujian Key Universities, School of Public Health, Fujian Medical University, Fuzhou 350004, China
    Arch Toxicol 85:901-10. 2011
    ..Taken together, these findings suggest that Nrf2 may play an important role in the protection of PC12 cells against MnCl(2) neurotoxicity...
  17. doi request reprint Chronic treatment with curcumin enhances methamphetamine locomotor sensitization and cue-induced reinstatement of methamphetamine self-administration
    Chun Zhao
    Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang 315211, PR China
    Pharmacol Biochem Behav 102:555-61. 2012
    ..Curcumin, a major active component of Curcuma longa, possesses antidepressant effects that are mediated by the 5-HT system. However, little is known about the effect of curcumin on the behavioral consequences of methamphetamine (METH)...
  18. pmc Negative moods correlate with craving in female methamphetamine users enrolled in compulsory detoxification
    Wenwen Shen
    Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Street, Ningbo, Zhejiang, P R China
    Subst Abuse Treat Prev Policy 7:44. 2012
    ..We characterized factors contributing to craving such as duration of detoxification, history of drug use and self-reported mood state...
  19. pmc Electroacupuncture suppresses discrete cue-evoked heroin-seeking and fos protein expression in the nucleus accumbens core in rats
    Sheng Liu
    Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, Ningbo 315010, China
    Evid Based Complement Alternat Med 2012:286404. 2012
    ..EA stimulation attenuated Fos expression in the core but not the shell of the NACc. Altogether, these results highlight the therapeutic benefit of EA in preventing relapse to drug addiction...
  20. doi request reprint Phosphodiesterase-5 inhibitor sildenafil prevents neuroinflammation, lowers beta-amyloid levels and improves cognitive performance in APP/PS1 transgenic mice
    Junfang Zhang
    Department of Pharmacology of Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang Province, 315211, PR China
    Behav Brain Res 250:230-7. 2013
    ..These results suggest that sildenafil could restore cognitive deficits in Tg APP/PS1 mice by the regulation of PKG/pCREB signaling, anti-inflammatory response and reduction of Aβ levels. ..
  21. ncbi request reprint Activation of the hypothalamus characterizes the response to acupuncture stimulation in heroin addicts
    Sheng Liu
    Ningbo Addiction Research and Treatment Center, Ningbo 315010, China
    Neurosci Lett 421:203-8. 2007
    ..An acupuncture sensation scale predicted the activation of the hypothalamus associated with the deqi sensation...
  22. doi request reprint Looking for a solution for drug addiction in China: exploring the challenges and opportunities in the way of China's new Drug Control Law
    Yu Liu
    School of Medicine, Ningbo University, Ningbo 315211, China
    Int J Drug Policy 21:149-54. 2010
    ..It is hoped that by addressing these issues, we will be able to implement the new Drug Control Law more successfully and ensure that we deal more effectively with drug addiction in China...
  23. doi request reprint Impact of catechol-o-methyltransferase polymorphisms on risperidone treatment for schizophrenia and its potential clinical significance
    Shugui Gao
    Department of Psychiatry, Ningbo Kangning Hospital, Ningbo, Zhejiang, China
    Clin Biochem 45:787-92. 2012
    ..The main aim was to study the effects of COMT polymorphisms on response of risperidone treatment for schizophrenia and investigate the correlation between memory function of schizophrenia patients and COMT polymorphisms...
  24. doi request reprint Differences in cigarette smoking behaviors among heroin inhalers versus heroin injectors
    Sheng Liu
    Ningbo Addiction Research and Treatment Center, Ningbo University School of Medicine, 42 Xibei Street, Ningbo 315010, PR China
    Nicotine Tob Res 13:1023-8. 2011
    ..The present study provided the first examination of cigarette smoking status, motivation, and cigarette smoking cue reactivity among injecting or inhaling heroin users...
  25. pmc N-acetylcysteine reduces extinction responding and induces enduring reductions in cue- and heroin-induced drug-seeking
    Wenhua Zhou
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Biol Psychiatry 63:338-40. 2008
    ..Previous studies show that the acute administration of N-acetylcysteine (NAC) inhibits the desire for cocaine in addicts and cocaine-seeking in animals...
  26. ncbi request reprint Suppression of morphine withdrawal syndrome by interleukin-2 and its gene
    Jinfa Gu
    Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, P R China
    Neuroreport 16:387-91. 2005
    ..These findings provided further evidence for the neuroregulatory function of an immunological molecule such as IL-2...
  27. ncbi request reprint Electroacupuncture attenuates morphine withdrawal signs and c-Fos expression in the central nucleus of the amygdala in freely moving rats
    Sheng Liu
    Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, P R China
    Brain Res 1044:155-63. 2005
    ..The new EA paradigm demonstrated in the present study might help the analysis of certain physiological responses induced by EA that would otherwise have been hindered by restraint stress...