Research Topics
| Wenhua ZhouSummaryCountry: China Publications
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Publications
Low dose of heroin inhibits drug-seeking elicited by cues after prolonged withdrawal from heroin self-administration in ratsWenhua Zhou
Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, 42 Xibei Str, Ningbo 315010, PR China
Neuroreport 15:727-30. 2004..The results suggest that prolonged withdrawal may increase the risk of relapse to heroin seeking...
Effects of training and withdrawal periods on heroin seeking induced by conditioned cue in an animal of model of relapseWenhua Zhou
Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Str, Ningbo, 315010, People s Republic of China
Psychopharmacology (Berl) 203:677-84. 2009..A high incidence of relapse can be triggered by exposure to conditioned cues previously associated with heroin. Extended access to drug and withdrawal are thought to affect the motivation for drug seeking...
Role of acetylcholine transmission in nucleus accumbens and ventral tegmental area in heroin-seeking induced by conditioned cuesW Zhou
Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Str, Ningbo 315010, PR China
Neuroscience 144:1209-18. 2007..Moreover, cue-induced reinstatement was inhibited by physostigmine in the NAc and potentiated by cholinergic stimulation in the VTA...- The dissociation of heroin-seeking patterns induced by contextual, discriminative, or discrete conditioned cues in a model of relapse to heroin in ratsWenhua Zhou
Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, People s Republic of China
Psychopharmacology (Berl) 181:197-206. 2005..The role of heroin-related stimuli in motivating the resumption of heroin use is not fully understood... - Galantamine attenuates the heroin seeking behaviors induced by cues after prolonged withdrawal in ratsHuifen Liu
Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Str, Ningbo 315010, PR China
Neuropharmacology 62:2515-21. 2012..The present studies investigated the effect of systemic or intra- LDT administration of galantamine, an inhibitor of acetylcholinesterase, on heroin-seeking induced by cues... - Increased c-Fos expression in the medial part of the lateral habenula during cue-evoked heroin-seeking in ratsFuqiang Zhang
Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, 42 Xibeijie St, Ningbo 315010, PR China
Neurosci Lett 386:133-7. 2005..This observation suggests the involvement of the LHb in mediating drug cue-induced heroin-seeking behavior after abstinence from self-administration of heroin... - Vagus nerve stimulation inhibits heroin-seeking behavior induced by heroin priming or heroin-associated cues in ratsHuifen Liu
Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Str, Ningbo 315010, Zhejiang Province, PR China
Neurosci Lett 494:70-4. 2011..The data suggest that vagus nerve stimulation may inhibit heroin- or heroin cue-induced relapse, possibly by regulation of the expression of Fos and CREB in nucleus accumbens... - Motivation of heroin-seeking elicited by drug-associated cues is related to total amount of heroin exposure during self-administration in ratsFuqiang Zhang
Laboratory of Behavioral Neuroscience, Ningbo Addiction Research and Treatment Center, 42 Xibeijie Street, Ningbo 315010, P R China
Pharmacol Biochem Behav 79:291-8. 2004..025 mg/kg. The results suggested that an increased motivation to seek heroin induced by drug-related cues is associated with the total amount of heroin intake... - Attitudes and knowledge about naloxone and overdose prevention among detained drug users in Ningbo, ChinaYu Liu
School of Medicine, Ningbo University, 818 Fenghua Street, Jiangbei District, Ningbo, Zhejiang 315211, China
Subst Abuse Treat Prev Policy 7:6. 2012..In addition, there has been no effort to integrate naloxone information and distribution into pre-release services for drug users detained in isolated compulsory detoxification facilities in China... - Temporal changes of smoking status and motivation among Chinese heroin-dependent, methadone-maintained smokersLonghui Li
Ningbo Addiction Research and Treatment Center, Ningbo University, PR China
Addict Behav 35:861-5. 2010..It remains undetermined whether smoking status and motivation would be differentially affected by heroin and methadone administration... - NF-E2-related factor 2 activation in PC12 cells: its protective role in manganese-induced damageHuangyuan Li
Department of Occupational and Environmental Health, Research Unit for Toxicology and Chemical Safety Assessment, Institution of Environmental and Health, Major Subject of Environment and Health of Fujian Key Universities, School of Public Health, Fujian Medical University, Fuzhou 350004, China
Arch Toxicol 85:901-10. 2011..Taken together, these findings suggest that Nrf2 may play an important role in the protection of PC12 cells against MnCl(2) neurotoxicity... - Chronic treatment with curcumin enhances methamphetamine locomotor sensitization and cue-induced reinstatement of methamphetamine self-administrationChun Zhao
Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang 315211, PR China
Pharmacol Biochem Behav 102:555-61. 2012..Curcumin, a major active component of Curcuma longa, possesses antidepressant effects that are mediated by the 5-HT system. However, little is known about the effect of curcumin on the behavioral consequences of methamphetamine (METH)... - Electroacupuncture suppresses discrete cue-evoked heroin-seeking and fos protein expression in the nucleus accumbens core in ratsSheng Liu
Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, Ningbo 315010, China
Evid Based Complement Alternat Med 2012:286404. 2012..EA stimulation attenuated Fos expression in the core but not the shell of the NACc. Altogether, these results highlight the therapeutic benefit of EA in preventing relapse to drug addiction... - Negative moods correlate with craving in female methamphetamine users enrolled in compulsory detoxificationWenwen Shen
Ningbo Addiction Research and Treatment Center, School of Medicine, Ningbo University, 42 Xibei Street, Ningbo, Zhejiang, P R China
Subst Abuse Treat Prev Policy 7:44. 2012..We characterized factors contributing to craving such as duration of detoxification, history of drug use and self-reported mood state... - Activation of the hypothalamus characterizes the response to acupuncture stimulation in heroin addictsSheng Liu
Ningbo Addiction Research and Treatment Center, Ningbo 315010, China
Neurosci Lett 421:203-8. 2007..An acupuncture sensation scale predicted the activation of the hypothalamus associated with the deqi sensation... - Looking for a solution for drug addiction in China: exploring the challenges and opportunities in the way of China's new Drug Control LawYu Liu
School of Medicine, Ningbo University, Ningbo 315211, China
Int J Drug Policy 21:149-54. 2010..It is hoped that by addressing these issues, we will be able to implement the new Drug Control Law more successfully and ensure that we deal more effectively with drug addiction in China... - Impact of catechol-o-methyltransferase polymorphisms on risperidone treatment for schizophrenia and its potential clinical significanceShugui Gao
Department of Psychiatry, Ningbo Kangning Hospital, Ningbo, Zhejiang, China
Clin Biochem 45:787-92. 2012..The main aim was to study the effects of COMT polymorphisms on response of risperidone treatment for schizophrenia and investigate the correlation between memory function of schizophrenia patients and COMT polymorphisms... - Differences in cigarette smoking behaviors among heroin inhalers versus heroin injectorsSheng Liu
Ningbo Addiction Research and Treatment Center, Ningbo University School of Medicine, 42 Xibei Street, Ningbo 315010, PR China
Nicotine Tob Res 13:1023-8. 2011..The present study provided the first examination of cigarette smoking status, motivation, and cigarette smoking cue reactivity among injecting or inhaling heroin users... - N-acetylcysteine reduces extinction responding and induces enduring reductions in cue- and heroin-induced drug-seekingWenhua Zhou
Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Biol Psychiatry 63:338-40. 2008..Previous studies show that the acute administration of N-acetylcysteine (NAC) inhibits the desire for cocaine in addicts and cocaine-seeking in animals... - Electroacupuncture attenuates morphine withdrawal signs and c-Fos expression in the central nucleus of the amygdala in freely moving ratsSheng Liu
Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, P.R. China
Brain Res 1044:155-63. 2005..The new EA paradigm demonstrated in the present study might help the analysis of certain physiological responses induced by EA that would otherwise have been hindered by restraint stress... - Suppression of morphine withdrawal syndrome by interleukin-2 and its geneJinfa Gu
Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, P.R. China
Neuroreport 16:387-91. 2005..These findings provided further evidence for the neuroregulatory function of an immunological molecule such as IL-2...