Qin Zhou


Country: China


  1. Zhou Y, Ge R, Wang R, Liu F, Huang Y, Liu H, et al. UXT potentiates angiogenesis by attenuating Notch signaling. Development. 2015;142:774-86 pubmed publisher
    ..Taken together, the data presented in this study characterize UXT as a novel repressor of Notch signaling, shedding new light on the molecular regulation of angiogenesis. ..
  2. Wei B, Cui Y, Huang Y, Liu H, Li L, Li M, et al. Tom70 mediates Sendai virus-induced apoptosis on mitochondria. J Virol. 2015;89:3804-18 pubmed publisher
    ..Interestingly, IKK-i plays an essential role in this activation. This study uncovers a novel mechanism of SeV-induced apoptosis. ..
  3. He Q, Chen L, Liu Y, Wu Y, Ni D, Liu J, et al. Gulo regulates the proliferation, apoptosis and mesenchymal-to-epithelial transformation of metanephric mesenchyme cells via inhibiting Six2. Biochem Biophys Res Commun. 2018;: pubmed publisher
    ..In conclusion, these findings reveal that Gulo promotes the MET and apoptosis, and inhibits proliferation in MM cells by down-regulating Six2. ..
  4. Li Y, Xie Y, Hao J, Liu J, Ning Y, Tang Q, et al. ER-localized protein-Herpud1 is a new mediator of IL-4-induced macrophage polarization and migration. Exp Cell Res. 2018;368:167-173 pubmed publisher
  5. Wang Q, Liu X, Zhou Q, Wang C. Cytosolic sensing of aberrant DNA: arming STING on the endoplasmic reticulum. Expert Opin Ther Targets. 2015;19:1397-409 pubmed publisher
    ..The relevant knowledge will greatly benefit the treatment of infectious diseases and identify potential targets for effective drug design. ..
  6. Liu J, Ju P, Zhou Y, Zhao Y, Xie Y, Long Y, et al. Six2 Is a Coordinator of LiCl-Induced Cell Proliferation and Apoptosis. Int J Mol Sci. 2016;17: pubmed publisher
    ..Together, these demonstrate that LiCl can induce the proliferation and apoptosis of MM cells coordinating with Six2. ..
  7. Liu Z, Zhou Y, Yuan Y, Nie F, Peng R, Li Q, et al. MiR542-3p Regulates the Epithelial-Mesenchymal Transition by Directly Targeting BMP7 in NRK52e. Int J Mol Sci. 2015;16:27945-55 pubmed publisher
    ..The effects of miR542-3p on regulating EMT could also be suppressed by transiently overexpressing BMP7 in NRK52e cells. Taken together, miR542-3p may be a critical mediator of the induction of EMT via directly targeting BMP7. ..
  8. Gu Y, Zhao Y, Zhou Y, Xie Y, Ju P, Long Y, et al. Zeb1 Is a Potential Regulator of Six2 in the Proliferation, Apoptosis and Migration of Metanephric Mesenchyme Cells. Int J Mol Sci. 2016;17: pubmed publisher
    ..These results indicated that there may exist a complicated regulation network between Six2 and Zeb1. Together, we demonstrate Zeb1 promotes proliferation and apoptosis and inhibits the migration of MM cells, in association with Six2. ..
  9. Peng R, Zhou L, Zhou Y, Zhao Y, Li Q, Ni D, et al. MiR-30a Inhibits the Epithelial--Mesenchymal Transition of Podocytes through Downregulation of NFATc3. Int J Mol Sci. 2015;16:24032-47 pubmed publisher
    ..In summary, we uncovered the protective function of miR30a targeting NFATc3 in the regulation of podocyte injury response to EMT. ..

More Information


  1. Yuan Y, Zhang J, Zhou Q. Overexpression of Jak1 Activating Mutants in Hepatocytes Is Insufficient to Generate Hepatocellular Carcinoma in Zebrafish. J Genet Genomics. 2016;43:99-102 pubmed publisher
  2. Mao Z, Lyu Z, Huang L, Zhou Q, Weng Y. T?RII Regulates the Proliferation of Metanephric Mesenchyme Cells through Six2 In Vitro. Int J Mol Sci. 2017;18: pubmed publisher
  3. Xia H, Yan X, Liu Y, Ju P, Liu J, Ni D, et al. Six2 is involved in GATA1-mediated cell apoptosis in mouse embryonic kidney-derived cell lines. In Vitro Cell Dev Biol Anim. 2017;53:827-833 pubmed publisher
    ..Our findings indicated that GATA1 may be a potential regulator of Six2-maintained population of nephron progenitor cells. ..
  4. Huang L, Wang H, Zhou Y, Ni D, Hu Y, Long Y, et al. Apobec-1 Complementation Factor (A1CF) Inhibits Epithelial-Mesenchymal Transition and Migration of Normal Rat Kidney Proximal Tubular Epithelial Cells. Int J Mol Sci. 2016;17: pubmed publisher
    ..Notably, the two A1CF variants led to the similar trend in the EMT process. Taken together, these data suggest that A1CF may be an antagonistic factor to the EMT process of kidney tubular epithelial cells. ..
  5. Zhou L, Hao J, Yuan Y, Peng R, Wang H, Ni D, et al. EIYMNVPV Motif is Essential for A1CF Nucleus Localization and A1CF (-8aa) Promotes Proliferation of MDA-MB-231 Cells via Up-Regulation of IL-6. Int J Mol Sci. 2016;17: pubmed publisher
    ..Thus, the EIYMNVPV motif could be developed as a potential target for basal-like breast cancer therapy. ..
  6. Zhou Y, He Q, Chen J, Liu Y, Mao Z, Lyu Z, et al. The expression patterns of Tetratricopeptide repeat domain 36 (Ttc36). Gene Expr Patterns. 2016;22:37-45 pubmed publisher
    ..Results showed the co-localization of Ttc36 with LTL rather than Calbindin-D28k. Collectively, on the basis of the expression pattern, Ttc36 is specifically expressed in proximal distal tubules. ..
  7. Ren D, Ju P, Liu J, Ni D, Gu Y, Long Y, et al. BMP7 plays a critical role in TMEM100-inhibited cell proliferation and apoptosis in mouse metanephric mesenchymal cells in vitro. In Vitro Cell Dev Biol Anim. 2018;54:111-119 pubmed publisher
    ..Our data demonstrated the significant role of BMP7 in Tmem100-regulated cell proliferation and apoptosis and revealed the complicated regulation network among Tmem100, BMP7, and BMPR-II in mouse embryonic kidney-derived cells. ..