Jin Zhou

Summary

Country: China

Publications

  1. doi request reprint Single-agent arsenic trioxide in the treatment of children with newly diagnosed acute promyelocytic leukemia
    Jin Zhou
    Department of Hematology, First Affiliated Hospital, Harbin Medical University, Harbin, China
    Blood 115:1697-702. 2010
  2. doi request reprint Arsenic trioxide induces procoagulant activity through phosphatidylserine exposure and microparticle generation in endothelial cells
    Jin Zhou
    Department of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin 150001, China
    Thromb Res 127:466-72. 2011
  3. ncbi request reprint Arsenic trioxide: an ancient drug revived
    Jin Zhou
    Department of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang 150001, China
    Chin Med J (Engl) 125:3556-60. 2012
  4. doi request reprint Daunorubicin induces procoagulant response through phosphatidylserine exposure in red blood cells
    Jin Zhou
    Department of Hematology, First Affiliated Hospital, Harbin Medical University, Harbin 150001, China
    Thromb Res 125:178-83. 2010
  5. ncbi request reprint [Effect of arsenic trioxide and daunorubicin on procoagulant activity of acute promyelocytic leukemia cells]
    Jia Lan Shi
    Department of Hematology, First Affiliated Hospital, Harbin Medical University, Harbin 150001, China
    Zhonghua Yi Xue Za Zhi 92:1095-9. 2012
  6. doi request reprint Daunorubicin induces procoagulant activity of cultured endothelial cells through phosphatidylserine exposure and microparticles release
    Yueyue Fu
    Department of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin, China
    Thromb Haemost 104:1235-41. 2010
  7. doi request reprint Long-term efficacy and safety of arsenic trioxide for first-line treatment of elderly patients with newly diagnosed acute promyelocytic leukemia
    Yingmei Zhang
    Central Laboratory, The First Affiliated Hospital, Harbin Medical University, Heilongjiang, China
    Cancer 119:115-25. 2013
  8. doi request reprint Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells
    Rui Xie
    Health Ministry Key Laboratory of Cell Transplantation, Heilongjiang Institute of Hematology and Oncology, Department of Hematology, The First Affiliated Hospital, Harbin Medical University, China
    Blood 119:2325-34. 2012
  9. pmc Identification of a known mutation in Notch 3 in familiar CADASIL in China
    Zhen Xuan Tan
    Genomics Research Center, Harbin Medical University, Harbin, China
    PLoS ONE 7:e36590. 2012
  10. doi request reprint A novel combination therapy with arsenic trioxide and parthenolide against pancreatic cancer cells
    Wei Wang
    Department of Hematology, The First Clinical College of Harbin Medical University, Harbin, China
    Pancreas 38:e114-23. 2009

Collaborators

Detail Information

Publications35

  1. doi request reprint Single-agent arsenic trioxide in the treatment of children with newly diagnosed acute promyelocytic leukemia
    Jin Zhou
    Department of Hematology, First Affiliated Hospital, Harbin Medical University, Harbin, China
    Blood 115:1697-702. 2010
    ..ATO resistance was observed in only 1 patient with a complex karyotype. The results indicate the high efficacy and safety of single-agent ATO regimens in the treatment of children with de novo APL...
  2. doi request reprint Arsenic trioxide induces procoagulant activity through phosphatidylserine exposure and microparticle generation in endothelial cells
    Jin Zhou
    Department of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin 150001, China
    Thromb Res 127:466-72. 2011
    ....
  3. ncbi request reprint Arsenic trioxide: an ancient drug revived
    Jin Zhou
    Department of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang 150001, China
    Chin Med J (Engl) 125:3556-60. 2012
    ..To summarize the clinical applications of arsenic trioxide (ATO) in the treatment of acute promyelocytic leukemia (APL), as well as non-APL malignancies and to discuss the mechanisms and adverse effects involved in ATO administration...
  4. doi request reprint Daunorubicin induces procoagulant response through phosphatidylserine exposure in red blood cells
    Jin Zhou
    Department of Hematology, First Affiliated Hospital, Harbin Medical University, Harbin 150001, China
    Thromb Res 125:178-83. 2010
    ..The present study aims to evaluate the possible impact of daunorubicin on phosphatidylserine exposure and consequent procoagulant property of red blood cells...
  5. ncbi request reprint [Effect of arsenic trioxide and daunorubicin on procoagulant activity of acute promyelocytic leukemia cells]
    Jia Lan Shi
    Department of Hematology, First Affiliated Hospital, Harbin Medical University, Harbin 150001, China
    Zhonghua Yi Xue Za Zhi 92:1095-9. 2012
    ..To explore the effect of arsenic trioxide (ATO) and daunorubicin (DNR) on phosphatidylserine (PS) exposure and related procoagulant activity of acute promyelocytic leukemia (APL) cells...
  6. doi request reprint Daunorubicin induces procoagulant activity of cultured endothelial cells through phosphatidylserine exposure and microparticles release
    Yueyue Fu
    Department of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin, China
    Thromb Haemost 104:1235-41. 2010
    ..Our results demonstrate that daunorubicin treatment enhanced PCA of HUVECs through PS exposure and shedding of procoagulant EMPs. Lactadherin acts as an efficient anticoagulant in this process...
  7. doi request reprint Long-term efficacy and safety of arsenic trioxide for first-line treatment of elderly patients with newly diagnosed acute promyelocytic leukemia
    Yingmei Zhang
    Central Laboratory, The First Affiliated Hospital, Harbin Medical University, Heilongjiang, China
    Cancer 119:115-25. 2013
    ..A significantly higher mortality during consolidation therapy was found, which is mainly due to deaths from sepsis following chemotherapy-induced myelosuppression...
  8. doi request reprint Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells
    Rui Xie
    Health Ministry Key Laboratory of Cell Transplantation, Heilongjiang Institute of Hematology and Oncology, Department of Hematology, The First Affiliated Hospital, Harbin Medical University, China
    Blood 119:2325-34. 2012
    ..These results suggest that engulfment by macrophages and endothelial cells reduce procoagulant and fibrinolytic activity of APL blasts. Lactadherin and phagocytosis could cooperatively ameliorate the clotting disorders in APL...
  9. pmc Identification of a known mutation in Notch 3 in familiar CADASIL in China
    Zhen Xuan Tan
    Genomics Research Center, Harbin Medical University, Harbin, China
    PLoS ONE 7:e36590. 2012
    ....
  10. doi request reprint A novel combination therapy with arsenic trioxide and parthenolide against pancreatic cancer cells
    Wei Wang
    Department of Hematology, The First Clinical College of Harbin Medical University, Harbin, China
    Pancreas 38:e114-23. 2009
    ..To investigate the anticancer effect and potential mechanism of combination treatment with arsenic trioxide (ATO) and parthenolide (PTL) in human pancreatic cancer cells...
  11. ncbi request reprint Effects of arsenic trioxide on voltage-dependent potassium channels and on cell proliferation of human multiple myeloma cells
    Jin Zhou
    Department of Hematology, First Clinical Medical College of Harbin Medical University, Harbin 150001, China
    Chin Med J (Engl) 120:1266-9. 2007
  12. ncbi request reprint Procoagulant activity and phosphatidylserine of amniotic fluid cells
    Jin Zhou
    Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, Harbin, China, 150001
    Thromb Haemost 101:845-51. 2009
    ..PS on AF cells is an important procoagulant source for AF. Lactadherin is an ideal anticoagulant for inhibiting the procoagulant activity of AF cells...
  13. doi request reprint Interaction of SDF-1alpha and CXCR4 plays an important role in pulmonary cellular infiltration in differentiation syndrome
    Jin Zhou
    Department of Hematology, The First Affiliated Hospital of Harbin Medical University, Harbin, China
    Int J Hematol 91:293-302. 2010
    ..The interaction of SDF-1alpha and CXCR4 plays an important role in pulmonary cellular infiltration during DS, suggesting that targeting SDF-1alpha and CXCR4 may provide the basis for potential treatments in the management of DS...
  14. doi request reprint Role of erythrocytes and platelets in the hypercoagulable status in polycythemia vera through phosphatidylserine exposure and microparticle generation
    Xiaoyan Tan
    Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, Harbin, China
    Thromb Haemost 109:1025-32. 2013
    ..Our data demonstrate that PV patients are characterised by increased circulating procoagulant MPs and PS exposing erythrocytes/platelets, which could contribute to the hypercoagulable state in these patients...
  15. doi request reprint Endothelial cell phagocytosis of senescent neutrophils decreases procoagulant activity
    Chunyan Gao
    Department of Medicine, The First Affiliated Hospital, Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin 150001, China
    Thromb Haemost 109:1079-90. 2013
    ..Thus, the ability of endothelial cells to clear senescent neutrophils may limit the procoagulant and/or inflammatory impact of these cells...
  16. ncbi request reprint Various tolerances to arsenic trioxide between human cortical neurons and leukemic cells
    Jin Zhou
    The First Hospital of Harbin Medical University, Harbin 150001, China
    Sci China C Life Sci 49:567-72. 2006
    ..This study revealed that cortical neuron was more tolerable to As2O3 compared to NB4. 1.0 micromol / L As2O3 showed little influence on cortical neuron but effectively promoted apoptosis and induced differentiation of NB4...
  17. doi request reprint Inheritance of the Salmonella virulence plasmids: mostly vertical and rarely horizontal
    Ye Feng
    Genomics Research Center, The State Province Key Laboratories of Biomedicine Pharmaceutics, Harbin Medical University, Harbin, China
    Infect Genet Evol 12:1058-63. 2012
    ..These findings demonstrate that Enteritidis acquired pSENV by horizontal transfer...
  18. ncbi request reprint Comparing two arsenic trioxide administration methods in APL therapy
    Jin Zhou
    Hematology Division, The First Clinical Medical College of Harbin Medical University, Harbin 150001, China
    Chin Med J (Engl) 117:1411-3. 2004
  19. ncbi request reprint [Clinical and experimental study of cardiac effects of conventional dosage arsenic trioxide in APL patients]
    Jin Zhou
    The First Clinical Medical College of Harbin Medical University, Harbin 150001, China
    Zhonghua Xue Ye Xue Za Zhi 25:31-4. 2004
    ..To investigate cardiac effects of arsenic trioxide (As(2)O(3)) at conventional dosage in acute promyelocytic leukemia (APL) patients...
  20. ncbi request reprint Association analysis of cytokine polymorphisms and plasma level in Northern Chinese Han patients with paroxysmal nocturnal hemoglobinuria
    Shu ye Wang
    Department of Hematology, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China
    Chin Med J (Engl) 125:1576-80. 2012
    ..The purpose of this study was to study cytokine gene single nucleotide polymorphisms (SNPs) and the correlated cytokine expression levels in relationship to the PNH pathogenesis...
  21. doi request reprint 4-aminopyridine induces apoptosis of human acute myeloid leukemia cells via increasing [Ca2+]i through P2X7 receptor pathway
    Wei Wang
    Department of Hematology, The First Affiliated Hospital of Harbin Medical University, Harbin, P R China
    Cell Physiol Biochem 28:199-208. 2011
    ..Knockdown of P(2)X(7) receptor by small interfering RNA blocked the effect of 4-AP. Conclusively, this study indicated that 4-AP promotes apoptosis in human AML cells via increasing [Ca(2+)](i) through P(2)X(7) receptor...
  22. ncbi request reprint [Expression and procoagulant activity of phosphatidylserine on the normal blood cells]
    Shu Chuan Liu
    Department of Hematology, The First Affiliated Hospital of Harbin Medical University, China
    Zhonghua Xue Ye Xue Za Zhi 32:858-62. 2011
    ..To investigate the expression and procoagulant activity of phosphatidylserine (PS) on the normal peripheral blood cells of adults...
  23. ncbi request reprint Increased procoagulant activity of red blood cells in the presence of cisplatin
    Cheng fang Lu
    Department of Hematology, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China
    Chin Med J (Engl) 121:1775-80. 2008
    ..Cisplatin based chemotherapy is a well recognized risk factor for coagulation disorders and thrombosis. The pathophysiological mechanisms by which cisplatin promote thrombosis are not well understood...
  24. ncbi request reprint [Adverse effects of intravenous arsenic trioxide and their prevention]
    Nan Wu
    Department of Hematology, The 12th People s Hospital of Guangzhou, Guangzhou 510620, China
    Zhonghua Nei Ke Za Zhi 45:310-3. 2006
    ..To study the main side effects of As(2)O(3) and the way of prevention...
  25. ncbi request reprint [In vitro stimulation of retinoic acid syndrome by rotary cell culture system and its relationship with expression of CXCR4 and SDF-1 alpha]
    Jin Zhou
    The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China
    Zhonghua Xue Ye Xue Za Zhi 28:799-803. 2007
    ..To explore the molecular mechanism and prevention of retinoic acid syndrome (RAS)...
  26. ncbi request reprint The effect of arsenic trioxide on QT interval prolongation during APL therapy
    Jin Zhou
    Department of Hematology, First Clinical College of Harbin Medical University, Harbin 150001, China
    Chin Med J (Engl) 116:1764-6. 2003
    ..To investigate the cardiac effect of QT interval prolongation in the treatment of acute promyelocytic leukemia (APL) with arsenic trioxide (As(2)O(3)), and the relationship between QT and serum arsenic concentration...
  27. doi request reprint T-cell clonality is detected in a high frequency among patients with incidental lymphocytosis by PCR assays for TCR gene rearrangements
    Fenglin Cao
    Department of Hematology, The First Hospital of Harbin Medical University, Harbin, China
    J Clin Pathol 66:749-52. 2013
    ..This study aimed to evaluate PCR-based clonality assays for the identification of T-cell clones among patients with unexplained lymphocytosis...
  28. ncbi request reprint Association of catalase genotype with oxidative stress in the predication of colorectal cancer: modification by epidemiological factors
    Dong Chang
    Department of Laboratory Diagnosis, The First Affiliated Hospital of the Harbin Medical University, Harbin 150001, Heilongliang, China
    Biomed Environ Sci 25:156-62. 2012
    ..This paper aims to assess the interaction between common variations in catalase (CAT) polymorphic gene and environmental factors for antioxidant defense enzyme in modulating individual susceptibility to colorectal cancer (CRC)...
  29. doi request reprint A novel mutation in CACNA1S gene associated with hypokalemic periodic paralysis which has a gender difference in the penetrance
    Fei Feng Li
    Genomics Research Center, Harbin Medical University, Harbin, China
    J Mol Neurosci 46:378-83. 2012
    ..This study expanded the spectrum of CACNA1S mutations associated with HypoPP and demonstrated a gender difference in the penetrance of the disease...
  30. ncbi request reprint [Association between subacute combined degeneration, vitamin B12 deficiency and megaloblastic anemia]
    Jin Zhou
    Department of Hematology, First Hospital of Harbin Medical University, Harbin 150001, China
    Zhonghua Nei Ke Za Zhi 43:90-3. 2004
    ..To investigate the association between subacute combined degeneration (SCD) and vitamin B(12) (VB(12)) deficiency and megaloblastic anemia (MA)...
  31. doi request reprint Immunohistochemical characterization and functional identification of mammary gland telocytes in the self-assembly of reconstituted breast cancer tissue in vitro
    Yongchao Mou
    Department of Advanced Interdisciplinary Studies, Institute of Basic Medical Sciences and Tissue Engineering Research Center, Academy of Military Medical Sciences, Beijing, China
    J Cell Mol Med 17:65-75. 2013
    ..In conclusion, we successfully reconstituted breast cancer tissue in vitro, and it seems to be attractive that TCs had potential functions in self-assembly of EMT-6/stromal cells reconstituted breast cancer tissue...
  32. pmc Complete genome sequence of Salmonella enterica serovar pullorum RKS5078
    Ye Feng
    Genomics Research Center, Harbin Medical University, Harbin, China
    J Bacteriol 194:744. 2012
    ..To validate this hypothesis and identify the decayed genes, we sequenced the complete genome of S. Pullorum RKS5078. We found 263 pseudogenes in this strain and conducted functional analyses of the decayed genes...
  33. doi request reprint An optimized RNA amplification method for prokaryotic expression profiling analysis
    Feng lin Cao
    The Institute of Hematology and Oncology of Heilongjiang Province, The First Clinical College of Harbin Medical University, Harbin, Heilongjiang, China
    Appl Microbiol Biotechnol 87:343-52. 2010
    ..coli RNA was only a small proportion of the simulated eukaryotic host RNA. The results suggest that PAOD is the preferred target preparation method for prokaryotic transcriptome...
  34. doi request reprint JAK/STAT and PI3K/AKT pathways form a mutual transactivation loop and afford resistance to oxidative stress-induced apoptosis in cardiomyocytes
    Yanjie Lu
    Department of Pharmacology State Province key lab of China, Harbin Medical University, Harbin, PR China
    Cell Physiol Biochem 21:305-14. 2008
    ....
  35. doi request reprint Propofol inhibited the delayed rectifier potassium current (I(k)) via activation of protein kinase C epsilon in rat parietal cortical neurons
    Chun yu Song
    Department of Anesthesiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China
    Eur J Pharmacol 653:16-20. 2011
    ..In conclusion, propofol inhibited I(K) via the activation of PKC epsilon in rat cerebral parietal cortical neurons...