Research Topics
Species | J GeSummaryAffiliation: Zhongshan Hospital Country: China Publications
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Detail Information
Publications
Elevated matrix metalloproteinase expression after stent implantation is associated with restenosisJunbo Ge
Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Fenglin Road 180, Shanghai 200032, People s Republic of China
Int J Cardiol 112:85-90. 2006..However, little is known about the relationship between early MMPs expression post-stent implantation and follow-up restenosis...- Advanced glycosylation end products might promote atherosclerosis through inducing the immune maturation of dendritic cellsJunbo Ge
Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, 180 Fenglin Rd, Shanghai 200032, People s Republic of China
Arterioscler Thromb Vasc Biol 25:2157-63. 2005..We therefore studied the effects of AGE-bovine serum albumin (AGE-BSA) on the maturation of DCs and the expressions of scavenger receptor-A (SR-A) and receptor for AGEs (RAGE) on DCs... 
Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathyJunbo Ge
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
Circ Arrhythm Electrophysiol 1:83-92. 2008..In this study, we identified and characterized, both in vitro and clinically, an SCN5A mutation associated with familial progressive atrioventricular block of adult onset and dilated cardiomyopathy in a Chinese family...- RACTS: a prospective randomized antiplatelet trial of cilostazol versus ticlopidine in patients undergoing coronary stenting: long-term clinical and angiographic outcomeJunbo Ge
Shanghai Institite of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Shanghai, China
J Cardiovasc Pharmacol 46:162-6. 2005.... - Effectiveness and safety of the sirolimus-eluting stents coated with bioabsorbable polymer coating in human coronary arteriesJunbo Ge
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Shanghai 200032, China
Catheter Cardiovasc Interv 69:198-202. 2007..As a drug reservoir, bioabsorbable polymer (polylactic acid, PLA) is more rational... - Enhanced myocardial cathepsin B expression in patients with dilated cardiomyopathyJunbo Ge
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Fenglin Road 180, Shanghai 200032, PR China
Eur J Heart Fail 8:284-9. 2006..The aim of this study was to investigate myocardial cathepsin B expression in failing and non-failing human hearts... 
Efficacy of emergent transcatheter transplantation of stem cells for treatment of acute myocardial infarction (TCT-STAMI)J Ge
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
Heart 92:1764-7. 2006..To study whether emergent intracoronary autologous bone marrow cell transplantation (BMT) is applicable for the treatment of acute myocardial infarction (AMI)...- Administration of intracoronary bone marrow mononuclear cells on chronic myocardial infarction improves diastolic functionK Yao
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
Heart 94:1147-53. 2008.... - Efficacy of statin pretreatment for the prevention of contrast-induced nephropathy: a meta-analysis of randomised controlled trialsL Zhang
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Shanghai Medical College of Fudan University, Shanghai, China
Int J Clin Pract 65:624-30. 2011..06 mg/dl, 95% CI -0.12 to 0.00 mg/dl, p = 0.05). The current cumulative evidence suggests that statin pretreatment may neither prevent CIN nor reduce the need for RRT. However, it may slightly decrease the level of SCr... - Effects of telomerase activity and apoptosis on ex vivo expansion of cord blood CD34(+) cellsJ Ge
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China
Cell Prolif 46:38-44. 2013..However, all exact roles remain to be elucidated. Here, change in telomerase activity and level of apoptosis in cord blood (CB) CD34(+) cells were evaluated together with specific cell population growth rate during ex vivo culture... - Epidemiology and clinical management of cardiomyopathies and heart failure in ChinaH Jiang
Department of Cardiology, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai 200032, China
Heart 95:1727-31. 2009..In this review the epidemiological data on cardiomyopathies, HF and current treatment for chronic HF among people living in China are summarised... - Simple versus complex stenting strategy for coronary artery bifurcation lesions in the drug-eluting stent era: a meta-analysis of randomised trialsF Zhang
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai 200032, China
Heart 95:1676-81. 2009.... - Telocytes in trachea and lungsY Zheng
Department of Pulmonary Medicine and Biomedical Research Center, Zhongshan Hospital, Fudan University, Shanghai, China
J Cell Mol Med 15:2262-8. 2011..IHC revealed positive expression of TC for c-kit, vimentin and CD34. In conclusion, this study shows the presence in trachea and lungs of a peculiar type of cells, which fulfils the criteria for TC... - Very late stent thrombosis in late stent malapposition after sirolimus-eluting stent implantationFeng Zhang
Department of Cardiology, Zhongshan Hospital, Shangai, China
Int Heart J 48:591-6. 2007..Thus, patients with LSM may pose a significant risk for very late ST after discontinuation of dual antiplatelet therapy. The findings suggest that dual antiplatelet therapy should be further prolonged in patients with LSM... - Purified human bone marrow multipotent mesenchymal stem cells regenerate infarcted myocardium in experimental ratsShaoheng Zhang
Stem Cell Research Center, Peking University, Hai Dian District, Beijing, China
Cell Transplant 14:787-98. 2005..These results indicate that transplantation of purified MMSCs from human bone marrow upregulated VEGF expression, enhanced angiogenesis, and improved the functional recovery following myocardial infarction in rats... - Host vascular niche contributes to myocardial repair induced by intracoronary transplantation of bone marrow CD34+ progenitor cells in infarcted swine heartShaoheng Zhang
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 180 Fen Lin Road, Shanghai 200032, China
Stem Cells 25:1195-203. 2007..Disclosure of potential conflicts of interest is found at the end of this article... - Safety and efficacy of the CYPHER Select Sirolimus-eluting stent in the "Real World"--clinical and angiographic results from the China CYPHER Select registryRun lin Gao
Chinese Society of Cardiology, China
Int J Cardiol 125:339-46. 2008..This post-marketing surveillance registry is aimed at determining the safety and reliability of the CYPHER Select Sirolimus-eluting stent (SES) in routine clinical practice... - Sirolimus-eluting stents in real-world patients with ST-segment elevation acute myocardial infarctionFeng Zhang
Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China
Int Heart J 48:303-11. 2007..Thus, this real-world registry confirmed the safety and efficacy of SES with remarkably lower rates of TVR and MACE in the setting of primary PCI for unselected patients with STEMI in a real-world scenario... - Arsenic trioxide eluting stent reduces neointima formation in a rabbit iliac artery injury modelWei Yang
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Cardiovasc Res 72:483-93. 2006..CONCLUSION: In a rabbit iliac artery model PLLA coated As2O3 eluting stent significantly suppressed in-stent restenosis by reducing proliferation and inducing apoptosis of VSMC... - Artery interposed to vein did not develop atherosclerosis and underwent atrophic remodeling in cholesterol-fed rabbitsHongqi Zhang
Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, 180 Fenglin Road, Shanghai 200032, PR China
Atherosclerosis 177:37-41. 2004.... - Ciglitazone inhibits oxidized-low density lipoprotein induced immune maturation of dendritic cellsYukun Luo
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China
J Cardiovasc Pharmacol 44:381-5. 2004..05 compared with ox-LDL, respectively). CONCLUSION: Our study suggested that one of the anti-inflammatory mechanisms of PPAR-gamma agonist ciglitazone was mediated by inhibiting the ox-LDL induced maturation and immune function of DCs... - Upregulation of lectinlike oxidized low-density lipoprotein receptor-1 expression contributes to the vein graft atherosclerosis: modulation by losartanJunbo Ge
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, People s Republic of China, 180 Fenglin Road, Shanghai 200032, PR China
Atherosclerosis 177:263-8. 2004..Increased LOX-1 expression was associated with vein grafts atherosclerosis development. Downregulation of LOX-1 by losartan might contribute to its attenuating effect on vein grafts atherosclerosis... - Time course of myocardial stromal cell-derived factor 1 expression and beneficial effects of intravenously administered bone marrow stem cells in rats with experimental myocardial infarctionJun Ma
Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Shanghai 200032, People s Republic of China
Basic Res Cardiol 100:217-23. 2005..We investigated the time course of myocardial SDF-1 expression and effects of intravenously administered bone marrow mesenchymal stem cells (MSC) in rats with myocardial infarction (MI)... - Cilostazol improves long-term outcomes after coronary stent implantationYaling Han
Department of Cardiology, Northern Hospital, Shenyang, China
Am Heart J 150:568. 2005 - Randomized comparison of carbon ion-implanted stent versus bare metal stent in coronary artery disease: the Asian Pacific Multicenter Arthos Stent Study (PASS) trialYoung-Hak Kim
Asan Medical Center, University of Ulsan College of Medicine Seoul, Republic of Korea
Am Heart J 149:336-41. 2005..1% in group 1 and 10.4% in group 2 (P = .73). CONCLUSIONS: The initial and long-term outcomes of the carbon ion-implanted stent were excellent. However, it did not improve long-term outcomes vs the bare metal stent... - Functional properties of a novel mutant of staphylokinase with platelet-targeted fibrinolysis and antiplatelet aggregation activitiesHongshan Chen
The Key Laboratory of Molecular Medicine, Ministry of Education, Dong an Road 130, Fudan University, and Department of Cardiology, Zhongshan Hospital, Shanghai, 200032, P R China
Eur J Pharmacol 566:137-44. 2007..These results suggested that RGD-SAK may serve as a potential thrombolytic agent with platelet-targeted fibrinolysis and antiplatelet aggregation activities... - Inhibition of activation of nuclear factor-KappaBeta enhances apoptosis induced by chemotherapeutic drugs in P388 cell lineJianhui Shi
Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Zhonghua Yi Xue Za Zhi 82:1050-3. 2002..Glucocorticoids, such as DXM, suppress the activation of NF-KappaBeta in leukemic cells, thus increasing the apoptosis induced by chemotherapeutic drugs... - Update on myocardial bridgingStefan Mohlenkamp
Clinic of Cardiology, University Clinic Essen, Germany
Circulation 106:2616-22. 2002 - Autologous mesenchymal stem cell transplantation induce VEGF and neovascularization in ischemic myocardiumYao Liang Tang
Department of Pediatrics, College of Medicine and All Children's Hospital Research Institute, University of South Florida, 140 7th Avenue S, CRI 2007, St. Petersburg, FL 33701, USA
Regul Pept 117:3-10. 2004..Hence, autologous MSCs transplantation may represent a promising therapeutic strategy free of ethical concerns and immune rejection, for neovascularization in ischemic heart diseases... - Postextrasystolic potentiation of vessel compression in myocardial bridging: detection by intravascular sonographyHolger Eggebrecht
Department of Cardiology, University Hospital of Essen, Hufelandstrasse 55, Germany
J Clin Ultrasound 30:312-6. 2002..Both intracoronary Doppler sonography and intravascular sonography provided important information that helped us to identify myocardial bridging in this patient... - Paracrine action enhances the effects of autologous mesenchymal stem cell transplantation on vascular regeneration in rat model of myocardial infarctionYao Liang Tang
Department of Physiology and Biophysics, College of Medicine, University of South Florida, St Petersburg, Florida, USA
Ann Thorac Surg 80:229-36; discussion 236-7. 2005..We hypothesize that transplantation of MSCs enhances vascular regeneration through a paracrine action... - Temporal changes in stem cells in the circulation and myocardium of mice with Coxsackie virus B3-induced myocarditisLan Zhao
Department of Paediatrics, First Hospital, University of South China, 69 Chuan Shan Road, Hengyang, Hunan 421001, China
Microvasc Res 75:358-66. 2008..These results demonstrate the rapid kinetics of progenitor cells during viral myocarditis and suggest that the optimal time to administer cell therapy to induce heart repair is within 2 weeks after viral infection... - Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activationNoritaka Yasuda
Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
EMBO Rep 9:179-86. 2008..Our results show that the AT(1) receptor undergoes a conformational switch that couples mechanical stress-induced activation and inverse agonist-induced inactivation... - Ageing-exaggerated proliferation of vascular smooth muscle cells is related to attenuation of Jagged1 expression in endothelial cellsXiaojing Wu
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China
Cardiovasc Res 77:800-8. 2008..The mechanism of how endothelium affects the growth of VSMC in the process remains unclear. We here examined the role of Jagged1, a regulator of cell growth... - Comparison of intravascular ultrasonic imaging with versus without incomplete stent apposition at follow-up after drug-eluting stent implantationJuying Qian
Department of Cardiology, Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai, China
Int J Cardiovasc Imaging 24:133-9. 2008..The aim of this study was to use intravascular ultrasound (IVUS) to evaluate the coronary characteristics after drug-eluting stent implantation in patients with ISA at follow-up... - Peripheral-blood dendritic cells in men with coronary heart diseaseHongyu Shi
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, People s Republic of China
Am J Cardiol 100:593-7. 2007..01). In conclusion, total peripheral-blood DCs are significantly higher in patients with CAD because of an increase in mDC subset, which might contribute to enhanced Th1 response in patients with CAD... - Increased heme oxygenase-1 expression in infarcted rat hearts following human bone marrow mesenchymal cell transplantationShaoheng Zhang
Department of Cardiology, the Third Hospital of Peking University, Beijing, China
Microvasc Res 69:64-70. 2005.... - Size of coronary artery in a myocardial bridge compared with adjacent nontunneled left anterior descending coronary arteryJuying Qian
Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China
Am J Cardiol 99:1653-5. 2007..74+/-0.61 vs 3.12+/-0.59 mm, p<0.001). In conclusion, our study showed that vessel area in the myocardial bridge segment was smaller than that in adjacent segments proximal and distal to MB... - Emodin induces growth arrest and death of human vascular smooth muscle cells through reactive oxygen species and p53Xiangfei Wang
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University Shanghai, China
J Cardiovasc Pharmacol 49:253-60. 2007..These findings collectively indicated that emodin induces both growth arrest and death of human VSMCs in 2 independent manners, implying it as a promising therapy for preventing restenosis... - The reasons coronary heart disease mortality has increased in ChinaLei Ge
Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China
Am Heart Hosp J 5:97-9. 2007.... - Comparison of various kinds of bone marrow stem cells for the repair of infarcted myocardium: single clonally purified non-hematopoietic mesenchymal stem cells serve as a superior sourceShaoheng Zhang
Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Shanghai 200032, China
J Cell Biochem 99:1132-47. 2006..We conclude that transplantation with single clonally purified MSCs seems to be more beneficial to the cardiac repair than with other stem cells after MI...