J Ge

Summary

Affiliation: Zhongshan Hospital
Country: China

Publications

  1. ncbi request reprint Elevated matrix metalloproteinase expression after stent implantation is associated with restenosis
    Junbo Ge
    Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Fenglin Road 180, Shanghai 200032, People s Republic of China
    Int J Cardiol 112:85-90. 2006
  2. ncbi request reprint Advanced glycosylation end products might promote atherosclerosis through inducing the immune maturation of dendritic cells
    Junbo Ge
    Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, 180 Fenglin Rd, Shanghai 200032, People s Republic of China
    Arterioscler Thromb Vasc Biol 25:2157-63. 2005
  3. ncbi request reprint RACTS: a prospective randomized antiplatelet trial of cilostazol versus ticlopidine in patients undergoing coronary stenting: long-term clinical and angiographic outcome
    Junbo Ge
    Shanghai Institite of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Shanghai, China
    J Cardiovasc Pharmacol 46:162-6. 2005
  4. doi request reprint Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy
    Junbo Ge
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
    Circ Arrhythm Electrophysiol 1:83-92. 2008
  5. ncbi request reprint Effectiveness and safety of the sirolimus-eluting stents coated with bioabsorbable polymer coating in human coronary arteries
    Junbo Ge
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Shanghai 200032, China
    Catheter Cardiovasc Interv 69:198-202. 2007
  6. ncbi request reprint Enhanced myocardial cathepsin B expression in patients with dilated cardiomyopathy
    Junbo Ge
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Fenglin Road 180, Shanghai 200032, PR China
    Eur J Heart Fail 8:284-9. 2006
  7. pmc Efficacy of emergent transcatheter transplantation of stem cells for treatment of acute myocardial infarction (TCT-STAMI)
    J Ge
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
    Heart 92:1764-7. 2006
  8. doi request reprint Administration of intracoronary bone marrow mononuclear cells on chronic myocardial infarction improves diastolic function
    K Yao
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
    Heart 94:1147-53. 2008
  9. doi request reprint The human MTHFR rs4846049 polymorphism increases coronary heart disease risk through modifying miRNA binding
    C Wu
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China
    Nutr Metab Cardiovasc Dis 23:693-8. 2013
  10. doi request reprint Efficacy of statin pretreatment for the prevention of contrast-induced nephropathy: a meta-analysis of randomised controlled trials
    L Zhang
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Shanghai Medical College of Fudan University, Shanghai, China
    Int J Clin Pract 65:624-30. 2011

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Elevated matrix metalloproteinase expression after stent implantation is associated with restenosis
    Junbo Ge
    Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Fenglin Road 180, Shanghai 200032, People s Republic of China
    Int J Cardiol 112:85-90. 2006
    ..However, little is known about the relationship between early MMPs expression post-stent implantation and follow-up restenosis...
  2. ncbi request reprint Advanced glycosylation end products might promote atherosclerosis through inducing the immune maturation of dendritic cells
    Junbo Ge
    Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, 180 Fenglin Rd, Shanghai 200032, People s Republic of China
    Arterioscler Thromb Vasc Biol 25:2157-63. 2005
    ..We therefore studied the effects of AGE-bovine serum albumin (AGE-BSA) on the maturation of DCs and the expressions of scavenger receptor-A (SR-A) and receptor for AGEs (RAGE) on DCs...
  3. ncbi request reprint RACTS: a prospective randomized antiplatelet trial of cilostazol versus ticlopidine in patients undergoing coronary stenting: long-term clinical and angiographic outcome
    Junbo Ge
    Shanghai Institite of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Shanghai, China
    J Cardiovasc Pharmacol 46:162-6. 2005
    ....
  4. doi request reprint Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy
    Junbo Ge
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
    Circ Arrhythm Electrophysiol 1:83-92. 2008
    ..In this study, we identified and characterized, both in vitro and clinically, an SCN5A mutation associated with familial progressive atrioventricular block of adult onset and dilated cardiomyopathy in a Chinese family...
  5. ncbi request reprint Effectiveness and safety of the sirolimus-eluting stents coated with bioabsorbable polymer coating in human coronary arteries
    Junbo Ge
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Shanghai 200032, China
    Catheter Cardiovasc Interv 69:198-202. 2007
    ..As a drug reservoir, bioabsorbable polymer (polylactic acid, PLA) is more rational...
  6. ncbi request reprint Enhanced myocardial cathepsin B expression in patients with dilated cardiomyopathy
    Junbo Ge
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Fenglin Road 180, Shanghai 200032, PR China
    Eur J Heart Fail 8:284-9. 2006
    ..The aim of this study was to investigate myocardial cathepsin B expression in failing and non-failing human hearts...
  7. pmc Efficacy of emergent transcatheter transplantation of stem cells for treatment of acute myocardial infarction (TCT-STAMI)
    J Ge
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
    Heart 92:1764-7. 2006
    ..To study whether emergent intracoronary autologous bone marrow cell transplantation (BMT) is applicable for the treatment of acute myocardial infarction (AMI)...
  8. doi request reprint Administration of intracoronary bone marrow mononuclear cells on chronic myocardial infarction improves diastolic function
    K Yao
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
    Heart 94:1147-53. 2008
    ....
  9. doi request reprint The human MTHFR rs4846049 polymorphism increases coronary heart disease risk through modifying miRNA binding
    C Wu
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China
    Nutr Metab Cardiovasc Dis 23:693-8. 2013
    ..Here, we tested whether a single-nucleotide polymorphism (SNP) located in the 3' untranslated region (UTR) of MTHFR was associated with CHD susceptibility by affecting microRNAs binding...
  10. doi request reprint Efficacy of statin pretreatment for the prevention of contrast-induced nephropathy: a meta-analysis of randomised controlled trials
    L Zhang
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Shanghai Medical College of Fudan University, Shanghai, China
    Int J Clin Pract 65:624-30. 2011
    ..06 mg/dl, 95% CI -0.12 to 0.00 mg/dl, p = 0.05). The current cumulative evidence suggests that statin pretreatment may neither prevent CIN nor reduce the need for RRT. However, it may slightly decrease the level of SCr...
  11. doi request reprint Effects of telomerase activity and apoptosis on ex vivo expansion of cord blood CD34(+) cells
    J Ge
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China
    Cell Prolif 46:38-44. 2013
    ..However, all exact roles remain to be elucidated. Here, change in telomerase activity and level of apoptosis in cord blood (CB) CD34(+) cells were evaluated together with specific cell population growth rate during ex vivo culture...
  12. doi request reprint Simple versus complex stenting strategy for coronary artery bifurcation lesions in the drug-eluting stent era: a meta-analysis of randomised trials
    F Zhang
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai 200032, China
    Heart 95:1676-81. 2009
    ....
  13. doi request reprint Epidemiology and clinical management of cardiomyopathies and heart failure in China
    H Jiang
    Department of Cardiology, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Heart 95:1727-31. 2009
    ..In this review the epidemiological data on cardiomyopathies, HF and current treatment for chronic HF among people living in China are summarised...
  14. doi request reprint Telocytes in trachea and lungs
    Y Zheng
    Department of Pulmonary Medicine and Biomedical Research Center, Zhongshan Hospital, Fudan University, Shanghai, China
    J Cell Mol Med 15:2262-8. 2011
    ..IHC revealed positive expression of TC for c-kit, vimentin and CD34. In conclusion, this study shows the presence in trachea and lungs of a peculiar type of cells, which fulfils the criteria for TC...
  15. ncbi request reprint Host vascular niche contributes to myocardial repair induced by intracoronary transplantation of bone marrow CD34+ progenitor cells in infarcted swine heart
    Shaoheng Zhang
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 180 Fen Lin Road, Shanghai 200032, China
    Stem Cells 25:1195-203. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  16. ncbi request reprint Safety and efficacy of the CYPHER Select Sirolimus-eluting stent in the "Real World"--clinical and angiographic results from the China CYPHER Select registry
    Run lin Gao
    Chinese Society of Cardiology, China
    Int J Cardiol 125:339-46. 2008
    ..This post-marketing surveillance registry is aimed at determining the safety and reliability of the CYPHER Select Sirolimus-eluting stent (SES) in routine clinical practice...
  17. ncbi request reprint Sirolimus-eluting stents in real-world patients with ST-segment elevation acute myocardial infarction
    Feng Zhang
    Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China
    Int Heart J 48:303-11. 2007
    ..Thus, this real-world registry confirmed the safety and efficacy of SES with remarkably lower rates of TVR and MACE in the setting of primary PCI for unselected patients with STEMI in a real-world scenario...
  18. ncbi request reprint Very late stent thrombosis in late stent malapposition after sirolimus-eluting stent implantation
    Feng Zhang
    Department of Cardiology, Zhongshan Hospital, Shangai, China
    Int Heart J 48:591-6. 2007
    ..Thus, patients with LSM may pose a significant risk for very late ST after discontinuation of dual antiplatelet therapy. The findings suggest that dual antiplatelet therapy should be further prolonged in patients with LSM...
  19. ncbi request reprint Arsenic trioxide eluting stent reduces neointima formation in a rabbit iliac artery injury model
    Wei Yang
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China
    Cardiovasc Res 72:483-93. 2006
    ..Arsenic trioxide (As2O3) is known to be a potent inhibitor of cell proliferation. We therefore studied the role of an As2O3 eluting stent in the prevention of restenosis in a rabbit iliac artery model...
  20. ncbi request reprint Time course of myocardial stromal cell-derived factor 1 expression and beneficial effects of intravenously administered bone marrow stem cells in rats with experimental myocardial infarction
    Jun Ma
    Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Shanghai 200032, People s Republic of China
    Basic Res Cardiol 100:217-23. 2005
    ..We investigated the time course of myocardial SDF-1 expression and effects of intravenously administered bone marrow mesenchymal stem cells (MSC) in rats with myocardial infarction (MI)...
  21. ncbi request reprint Purified human bone marrow multipotent mesenchymal stem cells regenerate infarcted myocardium in experimental rats
    Shaoheng Zhang
    Stem Cell Research Center, Peking University, Hai Dian District, Beijing, China
    Cell Transplant 14:787-98. 2005
    ..These results indicate that transplantation of purified MMSCs from human bone marrow upregulated VEGF expression, enhanced angiogenesis, and improved the functional recovery following myocardial infarction in rats...
  22. ncbi request reprint Cilostazol improves long-term outcomes after coronary stent implantation
    Yaling Han
    Department of Cardiology, Northern Hospital, Shenyang, China
    Am Heart J 150:568. 2005
  23. ncbi request reprint Artery interposed to vein did not develop atherosclerosis and underwent atrophic remodeling in cholesterol-fed rabbits
    Hongqi Zhang
    Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, 180 Fenglin Road, Shanghai 200032, PR China
    Atherosclerosis 177:37-41. 2004
    ....
  24. ncbi request reprint Upregulation of lectinlike oxidized low-density lipoprotein receptor-1 expression contributes to the vein graft atherosclerosis: modulation by losartan
    Junbo Ge
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, People s Republic of China, 180 Fenglin Road, Shanghai 200032, PR China
    Atherosclerosis 177:263-8. 2004
    ..Increased LOX-1 expression was associated with vein grafts atherosclerosis development. Downregulation of LOX-1 by losartan might contribute to its attenuating effect on vein grafts atherosclerosis...
  25. ncbi request reprint Ciglitazone inhibits oxidized-low density lipoprotein induced immune maturation of dendritic cells
    Yukun Luo
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, People s Republic of China
    J Cardiovasc Pharmacol 44:381-5. 2004
    ..The effects of PPARgamma on DCs maturation and immune function remain unknown now and we, therefore, studied the influence of PPARgamma agonist ciglitazone on the maturation and immune function of DCs...
  26. ncbi request reprint Randomized comparison of carbon ion-implanted stent versus bare metal stent in coronary artery disease: the Asian Pacific Multicenter Arthos Stent Study (PASS) trial
    Young Hak Kim
    Asan Medical Center, University of Ulsan College of Medicine Seoul, Republic of Korea
    Am Heart J 149:336-41. 2005
    ..This randomized multicenter clinical study was designed to determine if carbon ion-implanted stents reduce luminal late loss by blocking heavy metal ion diffusion into the surrounding tissue...
  27. doi request reprint Temporal changes in stem cells in the circulation and myocardium of mice with Coxsackie virus B3-induced myocarditis
    Lan Zhao
    Department of Paediatrics, First Hospital, University of South China, 69 Chuan Shan Road, Hengyang, Hunan 421001, China
    Microvasc Res 75:358-66. 2008
    ..These results demonstrate the rapid kinetics of progenitor cells during viral myocarditis and suggest that the optimal time to administer cell therapy to induce heart repair is within 2 weeks after viral infection...
  28. ncbi request reprint Postextrasystolic potentiation of vessel compression in myocardial bridging: detection by intravascular sonography
    Holger Eggebrecht
    Department of Cardiology, University Hospital of Essen, Hufelandstrasse 55, Germany
    J Clin Ultrasound 30:312-6. 2002
    ..Both intracoronary Doppler sonography and intravascular sonography provided important information that helped us to identify myocardial bridging in this patient...
  29. ncbi request reprint Autologous mesenchymal stem cell transplantation induce VEGF and neovascularization in ischemic myocardium
    Yao Liang Tang
    Department of Pediatrics, College of Medicine and All Children s Hospital Research Institute, University of South Florida, 140 7th Avenue S, CRI 2007, St Petersburg, FL 33701, USA
    Regul Pept 117:3-10. 2004
    ..Hence, autologous MSCs transplantation may represent a promising therapeutic strategy free of ethical concerns and immune rejection, for neovascularization in ischemic heart diseases...
  30. ncbi request reprint Update on myocardial bridging
    Stefan Mohlenkamp
    Clinic of Cardiology, University Clinic Essen, Germany
    Circulation 106:2616-22. 2002
  31. ncbi request reprint [Inhibition of activation of nuclear factor-KappaBeta enhances apoptosis induced by chemotherapeutic drugs in P388 cell line]
    Jianhui Shi
    Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Shanghai 200032, China
    Zhonghua Yi Xue Za Zhi 82:1050-3. 2002
    ..To explore the effects of glucocorticoid on apoptosis of mouse acute lymphocytic leukemia P388 cells and activation of nuclear factor-Kappa-gene binding (NF-KappaBeta) in P388 cells induced by chemotherapeutic drugs...
  32. ncbi request reprint Comparison of various kinds of bone marrow stem cells for the repair of infarcted myocardium: single clonally purified non-hematopoietic mesenchymal stem cells serve as a superior source
    Shaoheng Zhang
    Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Shanghai 200032, China
    J Cell Biochem 99:1132-47. 2006
    ..We conclude that transplantation with single clonally purified MSCs seems to be more beneficial to the cardiac repair than with other stem cells after MI...
  33. pmc Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation
    Noritaka Yasuda
    Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    EMBO Rep 9:179-86. 2008
    ..Our results show that the AT(1) receptor undergoes a conformational switch that couples mechanical stress-induced activation and inverse agonist-induced inactivation...
  34. ncbi request reprint Increased heme oxygenase-1 expression in infarcted rat hearts following human bone marrow mesenchymal cell transplantation
    Shaoheng Zhang
    Department of Cardiology, the Third Hospital of Peking University, Beijing, China
    Microvasc Res 69:64-70. 2005
    ....
  35. ncbi request reprint Comparison of intravascular ultrasonic imaging with versus without incomplete stent apposition at follow-up after drug-eluting stent implantation
    Juying Qian
    Department of Cardiology, Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai, China
    Int J Cardiovasc Imaging 24:133-9. 2008
    ..The aim of this study was to use intravascular ultrasound (IVUS) to evaluate the coronary characteristics after drug-eluting stent implantation in patients with ISA at follow-up...
  36. ncbi request reprint Peripheral-blood dendritic cells in men with coronary heart disease
    Hongyu Shi
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, People s Republic of China
    Am J Cardiol 100:593-7. 2007
    ..01). In conclusion, total peripheral-blood DCs are significantly higher in patients with CAD because of an increase in mDC subset, which might contribute to enhanced Th1 response in patients with CAD...
  37. ncbi request reprint Size of coronary artery in a myocardial bridge compared with adjacent nontunneled left anterior descending coronary artery
    Juying Qian
    Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China
    Am J Cardiol 99:1653-5. 2007
    ..74+/-0.61 vs 3.12+/-0.59 mm, p<0.001). In conclusion, our study showed that vessel area in the myocardial bridge segment was smaller than that in adjacent segments proximal and distal to MB...
  38. ncbi request reprint Emodin induces growth arrest and death of human vascular smooth muscle cells through reactive oxygen species and p53
    Xiangfei Wang
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University Shanghai, China
    J Cardiovasc Pharmacol 49:253-60. 2007
    ..These findings collectively indicated that emodin induces both growth arrest and death of human VSMCs in 2 independent manners, implying it as a promising therapy for preventing restenosis...
  39. ncbi request reprint The reasons coronary heart disease mortality has increased in China
    Lei Ge
    Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China
    Am Heart Hosp J 5:97-9. 2007
    ....
  40. ncbi request reprint Functional properties of a novel mutant of staphylokinase with platelet-targeted fibrinolysis and antiplatelet aggregation activities
    Hongshan Chen
    The Key Laboratory of Molecular Medicine, Ministry of Education, Dong an Road 130, Fudan University, and Department of Cardiology, Zhongshan Hospital, Shanghai, 200032, P R China
    Eur J Pharmacol 566:137-44. 2007
    ..These results suggested that RGD-SAK may serve as a potential thrombolytic agent with platelet-targeted fibrinolysis and antiplatelet aggregation activities...
  41. ncbi request reprint Paracrine action enhances the effects of autologous mesenchymal stem cell transplantation on vascular regeneration in rat model of myocardial infarction
    Yao Liang Tang
    Department of Physiology and Biophysics, College of Medicine, University of South Florida, St Petersburg, Florida, USA
    Ann Thorac Surg 80:229-36; discussion 236-7. 2005
    ..We hypothesize that transplantation of MSCs enhances vascular regeneration through a paracrine action...
  42. ncbi request reprint Ageing-exaggerated proliferation of vascular smooth muscle cells is related to attenuation of Jagged1 expression in endothelial cells
    Xiaojing Wu
    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China
    Cardiovasc Res 77:800-8. 2008
    ..The mechanism of how endothelium affects the growth of VSMC in the process remains unclear. We here examined the role of Jagged1, a regulator of cell growth...