Yang S, Wu B, Sun H, Sun T, Han K, Li D, et al
. Impaired insulin/IGF-1 is responsible for diabetic gastroparesis by damaging myenteric cholinergic neurones and interstitial cells of Cajal. Biosci Rep. 2017;37: pubmed publisher
..Insulin therapy in the early stage may delay diabetic gastroparesis. ..
Zou W, Yang S, Zhang T, Sun H, Wang Y, Xue H, et al
. Hypoxia enhances glucocorticoid-induced apoptosis and cell cycle arrest via the PI3K/Akt signaling pathway in osteoblastic cells. J Bone Miner Metab. 2015;33:615-24 pubmed publisher
Yang S, Lu W, Zhou D, Tang Y. Enriched environment increases myelinated fiber volume and length in brain white matter of 18-month female rats. Neurosci Lett. 2015;593:66-71 pubmed publisher
..0mm(3) in EE rats; so was the myelinated fiber length from 83.5 Â± 6.6 km in SE rats to 119.0 Â± 10.0 km in EE rats. Our data suggested that EE could protect brain white matter and its myelinated fibers of female rats at middle age. ..
Yang S, Wu B, Sun H, Ji F, Sun T, Zhao Y, et al
. Interrupted E2F1-miR-34c-SCF negative feedback loop by hyper-methylation promotes colorectal cancer cell proliferation. Biosci Rep. 2015;36:e00293 pubmed publisher
..In conclusion, our results suggested the existence of E2F1-miR-34c-SCF negative feedback loop which was interrupted by the hyper-methylation of miR-34c promoter in CRC cells and increased cell proliferation. ..
Xiao J, Yang S, Shen P, Wang Y, Sun H, Ji F, et al
. Phosphorylation of ETV4 at Ser73 by ERK kinase could block ETV4 ubiquitination degradation in colorectal cancer. Biochem Biophys Res Commun. 2017;486:1062-1068 pubmed publisher
..Our results will help understand the mechanism of ETV4 overexpression in CRC patients and provide a clue to search new therapeutic target to treat the related tumors in clinical practice. ..
Yang S, Li W, Sun H, Wu B, Ji F, Sun T, et al
. Resveratrol elicits anti-colorectal cancer effect by activating miR-34c-KITLG in vitro and in vivo. BMC Cancer. 2015;15:969 pubmed publisher
..Besides, Res exerted a synergistic effect with Oxa in a miR-34c dependent manner. We also suggested that Res-increased miR-34c could interfere IL-6-triggered CRC progression. ..