Fan S, Yang B, Zhi X, He M, Wang D, Wang Y, et al
. Are MTHFR C677T and MTRR A66G Polymorphisms Associated with Overweight/Obesity Risk? From a Case-Control to a Meta-Analysis of 30,327 Subjects. Int J Mol Sci. 2015;16:11849-63 pubmed publisher
..Further large-scale population-based studies, especially for the MTRR A66G polymorphism, are still needed to confirm or refute our findings. ..
Yang B, Fan S, Zhi X, Wang Y, Wang Y, Zheng Q, et al
. Prevalence of hyperhomocysteinemia in China: a systematic review and meta-analysis. Nutrients. 2014;7:74-90 pubmed publisher
..In summary, the prevalence of HHcy in China is high, particularly in northern populations, the inlanders, males, and the elderly. Homocysteine-lowering strategies are necessary to reduce this highly preventable disorder. ..
Yang B, Fan S, Zhi X, Wang D, Li Y, Wang Y, et al
. Associations of MTHFR C677T and MTRR A66G gene polymorphisms with metabolic syndrome: a case-control study in Northern China. Int J Mol Sci. 2014;15:21687-702 pubmed publisher
..The MTRR A66G polymorphism is not associated with MetS. However, it may exacerbate the effect of the MTHFR C677T variant alone. Further large prospective population-based studies are required to confirm our findings. ..
Fan S, Yang B, Zhi X, Wang Y, Wei J, Zheng Q, et al
. Interactions of Methylenetetrahydrofolate Reductase C677T Polymorphism with Environmental Factors on Hypertension Susceptibility. Int J Environ Res Public Health. 2016;13: pubmed publisher
Zhi X, Yang B, Fan S, Li Y, He M, Wang D, et al
. Additive Interaction of MTHFR C677T and MTRR A66G Polymorphisms with Being Overweight/Obesity on the Risk of Type 2 Diabetes. Int J Environ Res Public Health. 2016;13: pubmed
..Further large-scale studies are still needed to confirm our findings. ..