Deng F, Peng L, Li Z, Tan G, Liang E, Chen S, et al
. YAP triggers the Wnt/Î²-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury. Cell Death Dis. 2018;9:153 pubmed publisher
..In summary, nuclear YAP-driven IEC proliferation could control epithelial regeneration after inflammation and may serve as a potential therapeutic target in UC. However, excessive YAP activation promoted CAC development. ..
Tan G, Zeng B, Zhi F. Regulation of human enteric Î±-defensins by NOD2 in the Paneth cell lineage. Eur J Cell Biol. 2015;94:60-6 pubmed publisher
..In addition, this finding provides a new view on the function of NOD2 in regulating intestinal innate immunity. ..