Research Topics
Genomes and GenesSpecies | Chang Wei FengSummaryAffiliation: Zhengzhou University Country: China Publications
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Detail Information
Publications
Intervention and follow-up on human esophageal precancerous lesions in Henan, northern China, a high-incidence area for esophageal cancerLi Dong Wang
Laboratory for Cancer Research, College of Medicine, Zhengzhou University, Zhengzhou, Henan, 450052, People s Republic of China
Gan To Kagaku Ryoho 29:159-72. 2002..Human esophageal carcinogensis has been considered as a multistep progressive process. The natural history for EC, however is not very clear...
Expression of p53, inducible nitric oxide synthase and vascular endothelial growth factor in gastric precancerous and cancerous lesions: correlation with clinical featuresChang Wei Feng
Laboratory for Cancer Research, College of Medicine, Zhengzhou University, Zhengzhou, Henan, China
BMC Cancer 2:8. 2002..P53 suppresses angiogenesis by down-regulating VEGF and iNOS. The correlation of expression of p53, VEGF and iNOS and clinical features in gastric carcinogenesis, however, has not been well characterized...
Endoscopic screening and determination of p53 and proliferating cell nuclear antigen in esophageal multistage carcinogenesis: a comparative study between high- and low-risk populations in Henan, northern ChinaL Dong Wang
Laboratory for Cancer Research, College of Medicine, Zhengzhou University, Henan, China
Dis Esophagus 15:80-4. 2002..01). The remarkable difference was also observed between HIA and LIA in DYS and BCH. The present results indicate that p53 protein accumulation is an important early biomarker for identifying high-risk subjects for EC...
[Dysregulation of Annexin II expression in esophageal squamous cell cancer and adjacent tissues from a high-incidence area for esophageal cancer in Henan province]Yi Jun Qi
Henan Provincial Key Laboratory for Esophageal Cancer, Zhengzhou, Henan, 450052, P R China
Ai Zheng 26:730-6. 2007..This study was to detect the expression of Annexin II in esophageal squamous cell carcinoma (ESCC) and adjacent tissues, and to explore the role of Annexin II in ESCC pathogenesis and mechanisms...
[Serum proteomic profiles of the subjects with esophageal precancerous and cancerous lesions from Linzhou, an area with high incidence of esophageal cancer in Henan Province, Northern China]Li Dong Wang
Laboratory of Cancer Research, Experimental Center of Medicine Henan Provincial Key Laboratory for Esophageal Cancer, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, 450052, P R China
Ai Zheng 25:549-54. 2006....
Relevance of serum estradiol and estrogen receptor beta expression from a high-incidence area for esophageal squamous cell carcinoma in ChinaQi Ming Wang
Department of Oncology, The First Affiliated Hospital, Zhengzhou University, 450052 Zhengzhou, Henan, People s Republic of China
Med Oncol 28:188-93. 2011..The present results provide clues to explain the striking gender difference for ESCC, which warrants further investigations on potential applications of estrogen or analogs in prevention of ESCC...
Human papillomavirus DNA and P16(INK4A) expression in concurrent esophageal and gastric cardia cancersGuang Cheng Ding
Henan Key Laboratory for Esophageal Cancer Research, Department of Gastroenterology, The First Affiliated Hospital, College of Basic Medicine, Zhengzhou University, Zhengzhou 450052, Henan Province, China
World J Gastroenterol 16:5901-6. 2010..To investigate the relationship between human papillomavirus (HPV) infection and concurrent esophagus and gastric cardia cancer from the same patient (CC) and examine the significance of P16(INK4A) protein expression...
Cytological screening and 15 years' follow-up (1986-2001) for early esophageal squamous cell carcinoma and precancerous lesions in a high-risk population in Anyang County, Henan Province, Northern ChinaLi Dong Wang
Henan Key Laboratory for Esophageal Cancer, Laboratory for Cancer Research, College of Medicine, Zhengzhou University, Zhengzhou, Henan 450052, PR China
Cancer Detect Prev 29:317-22. 2005..SCC remains the leading cause of cancer-related death in these areas and the natural history for esophageal precancerous lesions is not clear...
Estrogen analogues: promising target for prevention and treatment of esophageal squamous cell carcinoma in high risk areasQi Ming Wang
Department of Oncology, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, PR China
Med Sci Monit 16:HY19-22. 2010..Our hypothesis suggests that administration of novel potent estrogen analogues might be an effective measure for prevention and treatment of ESCC in HIA...
[Absorption and elimination of photofrin-II in human immortalization esophageal epithelial cell line SHEE and its malignant transformation cell line SHEEC]She gan Gao
Henan Key Laboratory for Esophageal Cancer, Laboratory for Cancer Research, Basic Medical College, Zhengzhou University, Zhengzhou, Henan, 450052, P R China
Ai Zheng 28:1248-54. 2009..Conclusion: High photosensitizer concentration in tumor tissues may be not correlated with the affinity of tumor cells...
XPD Lys751Gln polymorphism and esophageal cancer risk: a meta-analysis involving 2288 cases and 4096 controlsLing Yuan
Department of Gastroenterology, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, Henan Province, China
World J Gastroenterol 17:2343-8. 2011..To evaluate the association between xeroderma pigmentosum group D (XPD), genetic polymorphism Lys751Gln and esophageal cancer risk...
[Comparative genomic hybridization: the profile of chromosomal imbalances in esophageal squamous cell carcinoma]Yan Ru Qin
Laboratory for Cancer Research, College of Medicine, Zhengzhou University, Zhengzhou 450052, China
Zhonghua Bing Li Xue Za Zhi 34:80-3. 2005..To characterize the profile of chromosomal imbalances of esophageal squamous cell carcinoma (SCC) in Linzhou, the high prevalence area of Henan province...
[Characterization of the changes in comparative genomic hybridization in esophageal cancer patients with family history]Zhi Wei Chang
Henan Provincial Key Laboratory for Esophageal Cancer Research, First Affiliated Hospital, Basic Medical College, Zhengzhou University, Zhengzhou, China
Nan Fang Yi Ke Da Xue Xue Bao 29:1166-9. 2009..To characterize the profile of chromosomal imbalances in esophageal cancer (EC) with or without family history in Linzhou, Henan Province of China...
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54Li Dong Wang
Cancer Research Center, Xinxiang Medical University, Xinxiang, Henan, China
Nat Genet 42:759-63. 2010..PLCE1 might regulate cell growth, differentiation, apoptosis and angiogenesis. C20orf54 is responsible for transporting riboflavin, and deficiency of riboflavin has been documented as a risk factor for ESCC and GCA...
