Quan Zhou

Summary

Affiliation: Zhejiang University
Country: China

Publications

  1. ncbi request reprint [Stereoselective determination of propranolol enantiomer in transgenic cell lines expressing human cytochrome P450]
    Xiao Feng Yan
    College of Pharmacy, Zhejiang University, Hangzhou 310031, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 32:116-20. 2003
  2. pmc Safe medication use based on knowledge of information about contraindications concerning cross allergy and comprehensive clinical intervention
    Wei Li
    Division of Medical Affairs, School of Medicine, Zhejiang University, Zhejiang, People s Republic of China
    Ther Clin Risk Manag 9:65-72. 2013
  3. pmc Appropriateness of administration of nasogastric medication and preliminary intervention
    Ling Ling Zhu
    Cadre Department, Zhejiang University, Hangzhou, Zhejiang Province, China
    Ther Clin Risk Manag 8:393-401. 2012
  4. pmc Prescribing practice and evaluation of appropriateness of enteral nutrition in a university teaching hospital
    Xiu ping Zhu
    Department of Pharmacy, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, People s Republic of China
    Ther Clin Risk Manag 9:37-43. 2013
  5. pmc Pharmacokinetic drug interaction profile of omeprazole with adverse consequences and clinical risk management
    Wei Li
    Division of Medical Affairs, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People s Republic of China
    Ther Clin Risk Manag 9:259-71. 2013
  6. pmc An outpatient antibacterial stewardship intervention during the journey to JCI accreditation
    Ping Song
    Department of Pharmacy, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Jiefang Road No, 88, Hangzhou, Zhejiang 310009, China
    BMC Pharmacol Toxicol 15:8. 2014
  7. doi request reprint Investigation on modulation of human P-gp by multiple doses of Radix Astragali extract granules using fexofenadine as a phenotyping probe
    Quan Zhou
    Department of Pharmacy, The Second Affiliated Hospital, School of Medicine, Zhejiang University, No 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China
    J Ethnopharmacol 146:744-9. 2013
  8. ncbi request reprint Pharmacokinetics and bioequivalence of ranitidine and bismuth derived from two compound preparations
    Quan Zhou
    Department of Clinical Pharmacology, The 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 12:2742-8. 2006
  9. ncbi request reprint Rational prescription of drugs within similar therapeutic or structural class for gastrointestinal disease treatment: drug metabolism and its related interactions
    Quan Zhou
    Department of Clinical Pharmacology and Clinical Pharmacy, The 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 13:5618-28. 2007
  10. pmc Drug utilization of clarithromycin for gastrointestinal disease treatment
    Quan Zhou
    Department of Clinical Pharmacy, Zhejiang University, Zhejiang Province 310009, China
    World J Gastroenterol 14:6065-71. 2008

Collaborators

Detail Information

Publications37

  1. ncbi request reprint [Stereoselective determination of propranolol enantiomer in transgenic cell lines expressing human cytochrome P450]
    Xiao Feng Yan
    College of Pharmacy, Zhejiang University, Hangzhou 310031, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 32:116-20. 2003
    ..To establish a chiro chromatography for studying the stereoselective metabolism of propranolol (PL) in S(9) incubates prepared from transgenic cell lines expressing human cytochrome P450...
  2. pmc Safe medication use based on knowledge of information about contraindications concerning cross allergy and comprehensive clinical intervention
    Wei Li
    Division of Medical Affairs, School of Medicine, Zhejiang University, Zhejiang, People s Republic of China
    Ther Clin Risk Manag 9:65-72. 2013
    ..An investigation of safety issues regarding information on contraindications related to cross allergy was conducted to promote clinical awareness and prevent medical errors in a 2200-bed tertiary care teaching hospital...
  3. pmc Appropriateness of administration of nasogastric medication and preliminary intervention
    Ling Ling Zhu
    Cadre Department, Zhejiang University, Hangzhou, Zhejiang Province, China
    Ther Clin Risk Manag 8:393-401. 2012
    ....
  4. pmc Prescribing practice and evaluation of appropriateness of enteral nutrition in a university teaching hospital
    Xiu ping Zhu
    Department of Pharmacy, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, People s Republic of China
    Ther Clin Risk Manag 9:37-43. 2013
    ..A retrospective utilization study was performed to evaluate utilization patterns for enteral nutrition in a university teaching hospital...
  5. pmc Pharmacokinetic drug interaction profile of omeprazole with adverse consequences and clinical risk management
    Wei Li
    Division of Medical Affairs, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People s Republic of China
    Ther Clin Risk Manag 9:259-71. 2013
    ....
  6. pmc An outpatient antibacterial stewardship intervention during the journey to JCI accreditation
    Ping Song
    Department of Pharmacy, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Jiefang Road No, 88, Hangzhou, Zhejiang 310009, China
    BMC Pharmacol Toxicol 15:8. 2014
    ..There are currently few reports on interventions to improve the quality of outpatient antibacterial prescribing...
  7. doi request reprint Investigation on modulation of human P-gp by multiple doses of Radix Astragali extract granules using fexofenadine as a phenotyping probe
    Quan Zhou
    Department of Pharmacy, The Second Affiliated Hospital, School of Medicine, Zhejiang University, No 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China
    J Ethnopharmacol 146:744-9. 2013
    ..Its use in combination with P-glycoprotein (P-gp) substrates is possible in clinical practice. Currently there is little knowledge about whether concomitant use of RA extract has an influence on disposition of P-gp substrate...
  8. ncbi request reprint Pharmacokinetics and bioequivalence of ranitidine and bismuth derived from two compound preparations
    Quan Zhou
    Department of Clinical Pharmacology, The 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 12:2742-8. 2006
    ..To evaluate the bioequivalence of ranitidine and bismuth derived from two compound preparations...
  9. ncbi request reprint Rational prescription of drugs within similar therapeutic or structural class for gastrointestinal disease treatment: drug metabolism and its related interactions
    Quan Zhou
    Department of Clinical Pharmacology and Clinical Pharmacy, The 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 13:5618-28. 2007
    ....
  10. pmc Drug utilization of clarithromycin for gastrointestinal disease treatment
    Quan Zhou
    Department of Clinical Pharmacy, Zhejiang University, Zhejiang Province 310009, China
    World J Gastroenterol 14:6065-71. 2008
    ..To evaluate the patterns of use of clarithromycin for gastrointestinal disease treatment and promote its rational use...
  11. ncbi request reprint CYP2C9*3(1075A > C), ABCB1 and SLCO1B1 genetic polymorphisms and gender are determinants of inter-subject variability in pitavastatin pharmacokinetics
    Quan Zhou
    Department of Pharmacy, The 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    Pharmazie 68:187-94. 2013
    ..521T>C, SLCO1B1 g.11187G > A, SLCO1B1*17 and gender contribute to inter-subject variability in pitavastatin pharmacokinetics. Personalized medicine should be necessary for hypercholesterolaemic patients receiving pitavastatin...
  12. ncbi request reprint ABCB1 gene polymorphisms, ABCB1 haplotypes and ABCG2 c.421c > A are determinants of inter-subject variability in rosuvastatin pharmacokinetics
    Quan Zhou
    Department of Pharmacy, The 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou China
    Pharmazie 68:129-34. 2013
    ..421C > A are determinants of inter-subject variability in rosuvastatin pharmacokinetics in healthy Chinese volunteers, and potentially affect the efficacy and toxicity of statin therapy...
  13. ncbi request reprint Quantitative determination of domperidone in human plasma by ultraperformance liquid chromatography with electrospray ionization tandem mass spectrometry
    Dong Hang Xu
    Division of Clinical Pharmacology, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou 310009, People s Republic of China
    Biomed Chromatogr 22:433-40. 2008
    ..43-6.26%, an inter-assay precision 5.25-7.45% and an overall accuracy (relative error) of <6.92%. The method can be applied to pharmacokinetic and bioequivalence studies of domperidone...
  14. pmc Poor awareness of preventing aspirin-induced gastrointestinal injury with combined protective medications
    Ling Ling Zhu
    Geriatric Ward, The 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 18:3167-72. 2012
    ..To investigate prescribing pattern in low-dose aspirin users and physician awareness of preventing aspirin-induced gastrointestinal (GI) injury with combined protective medications...
  15. ncbi request reprint Simvastatin pharmacokinetics in healthy Chinese subjects and its relations with CYP2C9, CYP3A5, ABCB1, ABCG2 and SLCO1B1 polymorphisms
    Quan Zhou
    Department of Pharmacy, The 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
    Pharmazie 68:124-8. 2013
    ..The gene-dose effects of ABCG2 c.421 C > A and CYP3A5*3 g.6986A > G on simvastatin pharmacokinetics are not strong enough in Chinese subjects...
  16. ncbi request reprint Quantitative determination of rosuvastatin in human plasma by liquid chromatography with electrospray ionization tandem mass spectrometry
    Dong Hang Xu
    Division of Clinical Pharmacology, The Second Affiliated Hospital School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou 310009, China
    Rapid Commun Mass Spectrom 20:2369-75. 2006
    ..97-15.94%, an inter-assay precision 3.19-15.27%, and an overall accuracy (relative error) of < 3.7%. The method can be applied to pharmacokinetic or bioequivalence studies of rosuvastatin...
  17. ncbi request reprint Carbon-carbon double-bond reductases in nature
    Minmin Huang
    Department of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China and
    Drug Metab Rev 46:362-78. 2014
    ....
  18. ncbi request reprint [Chiral separation of fluvastatin enantiomers with in vitro cellular method]
    Bo xuan Qu
    Department of Pharmaceutical Analysis and Drug Metabolism, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 40:12-6. 2011
    ..To establish a chiral separation method for determination of fluvastatin enantiomer with in vitro cellular model...
  19. doi request reprint Hepatic glucuronidation of isoneochamaejasmin a from the traditional Chinese medicine Stellera chamaejasme L. Root
    Lushan Yu
    Department of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China L Y, M Z, X Z, Y L, H H, H J, S Z Institute of Materia Medica, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China J P, Y C, S C, J C and Department of Pharmacy, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China Q Z
    Drug Metab Dispos 42:735-43. 2014
    ..These findings collectively indicate that UGT1A1 is the major enzyme in the formation of M1, whereas UGT1A3 is the major enzyme in the formation of M2...
  20. ncbi request reprint [Effects of L-tetrahydropalmatine on concentrations of neurotransmitter amino acids in mice with cerebral ischemia]
    Zhong Miao Zhang
    Department of Clinical Pharmacy, The Second Affiliated Hospital, College of Medicinal Sciences, Zhejiang University, Hangzhou 310009, China
    Zhongguo Zhong Yao Za Zhi 29:371-3. 2004
    ..To observe the effects of L-tetrahydropalmatine (L-THP) on concentrations of neurotransmitter amino acids in mice with cerebral ischemia and to discuss the mechanisms of L-THP in tyreating cerebral ischemia...
  21. ncbi request reprint Stereoselectivity of chiral drug transport: a focus on enantiomer-transporter interaction
    Quan Zhou
    Department of Pharmacy, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China and
    Drug Metab Rev 46:283-90. 2014
    ..Modulation of specific drug transporter by pure enantiomers might exhibit opposite stereoselectivity. Further studies with integrated approaches will open up new horizons in stereochemistry of pharmacokinetics. ..
  22. ncbi request reprint Use of evidence-based pharmacotherapy for secondary prevention of coronary heart disease: A Chinese medicine hospital versus a general hospital
    Hui Min Xu
    Department of Pharmacy, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310009, China
    Chin J Integr Med 20:375-80. 2014
    ..To determine differences in adherence to secondary prevention guidelines (pharmacological interventions) among coronary heart disease (CHD) patients between a Chinese medicine (CM) hospital and a general hospital in a Chinese city...
  23. ncbi request reprint [Establishment of reverse-phase high-performance liquid chromatography with chiral reagent derivatization for separation of fexofenadine enantiomers]
    Qing Qing Yao
    Laboratory of Pharmaceutical Analysis and Drug Metabolism, College of Pharmaceutical Sciences, Zhejiang Provincial Key Laboratory of Anti Cancer Drug Research, Zhejiang University, Hangzhou 310058, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 43:155-9. 2014
    ..To establish a precolumn chiral derivatization method for determination of fexofenadine enantiomers, a chiral substrate of OATP1B1, in cellular model...
  24. doi request reprint Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro
    Lushan Yu
    Laboratory of Pharmaceutical Analysis and Drug Metabolism, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China
    Biopharm Drug Dispos 34:278-87. 2013
    ..The results of this study provide useful information for predicting CYP2C8 phenotypes and may contribute to individualized drug therapy in the future...
  25. ncbi request reprint In vitro characterization of ABC transporters involved in the absorption and distribution of liensinine and its analogs
    Lushan Yu
    Laboratory of Pharmaceutical of Analysis and Drug Metabolism, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
    J Ethnopharmacol 150:485-91. 2013
    ..Liensinine and its analogs neferine and isoliensinine are the major active components in lotus plumule. Aim of the study is to investigate the association of liensinine, neferine, and isoliensinine with efflux transporters...
  26. ncbi request reprint Effects of stereochemical aspects on drug interaction in pharmacokinetics
    Quan Zhou
    Department of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031, China
    Acta Pharmacol Sin 23:385-92. 2002
    ..Study in this respect should be enhanced...
  27. ncbi request reprint An overview of ABC and SLC drug transporter gene regulation
    Qiu xia Chen
    Department of Pharmaceutical Analysis and Drug Metabolism, Zhejiang University, Hangzhou, Zhejiang 310058, China
    Curr Drug Metab 14:253-64. 2013
    ....
  28. pmc Drug-induced liver injury in hospitalized patients with notably elevated alanine aminotransferase
    Hui Min Xu
    Department of Pharmacy, The 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 18:5972-8. 2012
    ..To identify the proportion, causes and the nature of drug-induced liver injury (DILI) in patients with notably elevated alanine aminotransferase (ALT)...
  29. ncbi request reprint Roles of UDP-glucuronosyltransferases in phytochemical metabolism of herbal medicines and the associated herb-drug interactions
    Li Li
    Department of Pharmaceutical Analysis and Drug Metabolism, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    Curr Drug Metab 13:615-23. 2012
    ..In this review, the research advances of the potential for commonly used herbal medicines as UGT substrate and modulator are summarized. In addition, the herb-drug interactions associated with UGTs are also discussed...
  30. doi request reprint An investigation of oxidative DNA damage in pharmacy technicians exposed to antineoplastic drugs in two Chinese hospitals using the urinary 8-OHdG assay
    Yu Wen Huang
    The Second Affiliated Hospital of College of Medicine of Zhejiang University, Hangzhou, Zhejiang, China
    Biomed Environ Sci 25:109-16. 2012
    ..To investigate oxidative DNA damage in pharmacy technicians preparing antineoplastic drugs at the PIVAS (Pharmacy Intravenous Admixture Service) in two Chinese hospitals...
  31. ncbi request reprint Quantitation of yeast ceramides using high-performance liquid chromatography-evaporative light-scattering detection
    Quan Zhou
    Department of Biological Science and Biotechnology, Tsinghua University, Beijing 100084, China
    J Chromatogr B Analyt Technol Biomed Life Sci 780:161-9. 2002
    ..The method can be applied for routine assay of ceramide content in yeast...