Shu Zheng

Summary

Affiliation: Zhejiang University
Country: China

Publications

  1. ncbi request reprint Protein interaction analysis of ST14 domains and their point and deletion mutants
    Weiting Ge
    College of Life Science, Zhejiang University, Hangzhou 310029, China
    J Biol Chem 281:7406-12. 2006
  2. ncbi request reprint [Exploration of translational medicine research in metastasis and invasion of malignant tumors]
    Shu Zheng
    Cancer Institute Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
    Zhonghua Wei Chang Wai Ke Za Zhi 17:1-5. 2014
  3. ncbi request reprint [Proliferative and invasive effects of inhibitors of kinase 4(P15(ink4b) and P16(ink4a)/CDKN2) gene activation on RKO human colorectal cancer cells]
    Xiaoming Fang
    Cancer Institute, Zhejiang University School of Medicine, Hangzhou 310009, China
    Zhonghua Wei Chang Wai Ke Za Zhi 17:31-5. 2014
  4. ncbi request reprint [Translational medicine of colorectal cancer]
    Shu Zheng
    Zhejiang University School of Medicine, Hangzhou, China
    Zhonghua Wei Chang Wai Ke Za Zhi 16:4-7. 2013
  5. pmc A giant hemolymphangioma of the pancreas in a 20-year-old girl: a report of one case and review of the literature
    Li Feng Sun
    Department of Surgical Oncology, The Second Affiliated Hospital, College of Medicine, Zhejinag University, Hangzhou Zhejiang 310009, PR China
    World J Surg Oncol 7:31. 2009
  6. pmc The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis
    Xuefeng Fang
    Swedish Neuroscience Institute, Swedish Medical Center, Seattle, WA 98122, USA
    BMC Genomics 12:11. 2011
  7. ncbi request reprint Continuous release of interleukin 12 from microencapsulated engineered cells for colon cancer therapy
    Shu Zheng
    Cancer Institute, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 9:951-5. 2003
  8. ncbi request reprint [Challenge and opportunity in prevention and treatment of colorectal cancer in China]
    Shu Zheng
    The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 33:375-8. 2004
  9. pmc Hereditary colorectal cancer in china
    Zheng Shu
    Cancer Institute, Second Affiliated Hospital, Zhejiang University, Hangzhou, PR China
    Hered Cancer Clin Pract 3:155-64. 2005
  10. doi request reprint The novel human endogenous retrovirus-related gene, psiTPTE22-HERV, is silenced by DNA methylation in cancers
    Qiaoyi Liang
    Cancer Institute, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
    Int J Cancer 127:1833-43. 2010

Collaborators

Detail Information

Publications120 found, 100 shown here

  1. ncbi request reprint Protein interaction analysis of ST14 domains and their point and deletion mutants
    Weiting Ge
    College of Life Science, Zhejiang University, Hangzhou 310029, China
    J Biol Chem 281:7406-12. 2006
    ..Finally, homology modeling studies suggested that TMEFF1 might form a complex with ST14 by an interaction between epidermal growth factor and CUB domains...
  2. ncbi request reprint [Exploration of translational medicine research in metastasis and invasion of malignant tumors]
    Shu Zheng
    Cancer Institute Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
    Zhonghua Wei Chang Wai Ke Za Zhi 17:1-5. 2014
    ..It will be the new era for cancer prevention and intervention in translational medicine area. ..
  3. ncbi request reprint [Proliferative and invasive effects of inhibitors of kinase 4(P15(ink4b) and P16(ink4a)/CDKN2) gene activation on RKO human colorectal cancer cells]
    Xiaoming Fang
    Cancer Institute, Zhejiang University School of Medicine, Hangzhou 310009, China
    Zhonghua Wei Chang Wai Ke Za Zhi 17:31-5. 2014
    ..To explore the proliferation and invasive effects of inhibitors of kinase 4(INK4)(P15(ink4b) and P16(ink4a)/CDKN2) gene protein activation on RKO human colorectal cell in vivo and in vitro...
  4. ncbi request reprint [Translational medicine of colorectal cancer]
    Shu Zheng
    Zhejiang University School of Medicine, Hangzhou, China
    Zhonghua Wei Chang Wai Ke Za Zhi 16:4-7. 2013
    ..Based on the concept of micro environment, molecular targeted drugs to interfere with metastasis and invasion and new concepts of surgical resection margin and neoadjuvant therapy will gain recognition from clinicians...
  5. pmc A giant hemolymphangioma of the pancreas in a 20-year-old girl: a report of one case and review of the literature
    Li Feng Sun
    Department of Surgical Oncology, The Second Affiliated Hospital, College of Medicine, Zhejinag University, Hangzhou Zhejiang 310009, PR China
    World J Surg Oncol 7:31. 2009
    ..Hemolymphangioma of the pancreas is a very rare benign tumor. There were only six reports of this disease until December 2008. Herein, we report a case of giant hemolymphangioma of the pancreas in a 20-year-old girl...
  6. pmc The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis
    Xuefeng Fang
    Swedish Neuroscience Institute, Swedish Medical Center, Seattle, WA 98122, USA
    BMC Genomics 12:11. 2011
    ..SOX2 appears to re-activate in several human cancers including glioblastoma multiforme (GBM), however, the detailed response program of SOX2 in GBM has not yet been defined...
  7. ncbi request reprint Continuous release of interleukin 12 from microencapsulated engineered cells for colon cancer therapy
    Shu Zheng
    Cancer Institute, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 9:951-5. 2003
    ..To explore the anti-tumor immunity against CT26 colon tumor of the microencapsulated cells modified with murine interleukine-12 (mIL-12) gene...
  8. ncbi request reprint [Challenge and opportunity in prevention and treatment of colorectal cancer in China]
    Shu Zheng
    The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 33:375-8. 2004
  9. pmc Hereditary colorectal cancer in china
    Zheng Shu
    Cancer Institute, Second Affiliated Hospital, Zhejiang University, Hangzhou, PR China
    Hered Cancer Clin Pract 3:155-64. 2005
    ..Total resection of the colon and rectum is necessary in FAP patients. For unresectable duodenal polyps, chemopreventive agents may be used...
  10. doi request reprint The novel human endogenous retrovirus-related gene, psiTPTE22-HERV, is silenced by DNA methylation in cancers
    Qiaoyi Liang
    Cancer Institute, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
    Int J Cancer 127:1833-43. 2010
    ..These results suggest psiTPTE22-HERV is regulated epigenetically by DNA methylation. Our study paved the way for further study on an interesting HERV-related human-specific gene, which is silenced in cancers by DNA methylation...
  11. ncbi request reprint Expression of SNC73, a transcript of the immunoglobulin alpha-1 gene, in human epithelial carcinomas
    Li Yi Geng
    Cancer Institute, Zhejiang University School of Medicine, The Second Affiliated Teaching Hospital, 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 13:2305-11. 2007
    ..To investigate the expression of SNC73, a trans-cript of the immunoglobulin alpha-1 gene (IgA1-H chain), in human epithelia-derived tumor cells...
  12. ncbi request reprint The Helicobacter pylori virulence factor CagA promotes Erk1/2-mediated Bad phosphorylation in lymphocytes: a mechanism of CagA-inhibited lymphocyte apoptosis
    Yongliang Zhu
    Department of Gastroenterology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
    Cell Microbiol 9:952-61. 2007
    ..Our results reveal that CagA, to some extent like IL-3, can enhance lymphocytes' ability to evade apoptosis through phosphorylation of Bad. This may account, at least in part, for the ability of CagA to promote lymphomagenesis...
  13. ncbi request reprint Honokiol: a potent chemotherapy candidate for human colorectal carcinoma
    Fei Chen
    Cancer Institute, Second Affiliated Hospital of Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 10:3459-63. 2004
    ..To investigate the anticancer activity of honokiol on RKO, a human colorectal carcinoma cell line in vitro and in vivo, and to evaluate its possible use in clinic...
  14. doi request reprint Frequent epigenetic silencing of PCDH10 by methylation in human colorectal cancer
    Xian Zhong
    Cancer Institute Key Laboratory for Cancer Intervention and Prevention, China National Ministry of Education, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
    J Cancer Res Clin Oncol 139:485-90. 2013
    ..Recently, methylation of PCDH10 was reported to be associated with multiple hematologic malignancies as well as some solid tumors. Whether the down-regulation of PCDH10 happens in CRC remains unknown...
  15. doi request reprint Performance of a colorectal cancer screening protocol in an economically and medically underserved population
    Shan Rong Cai
    Cancer Institute, Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Zhejiang Province, PR China
    Cancer Prev Res (Phila) 4:1572-9. 2011
    ..Men had a higher prevalence of advanced neoplasm than women. Results indicate that combining FITs and HRFQ as primary screening methods is an efficient CRC screening strategy in economically and medically underserved populations...
  16. ncbi request reprint [Preoperative molecular staging of colorectal cancers by CM10 ProteinChip and SELDI-TOF-MS analysis]
    Wen Hong Xu
    Department of Oncology, Cancer Institute, Clinical Laboratory, Second Affiliated Hospital of Zhejiang University College of Medicine, Hangzhou 310009, China
    Zhonghua Zhong Liu Za Zhi 28:753-7. 2006
    ..To detect the serum proteomic patterns by using SELDI-TOF-MS and CM10 ProteinChip techniques in colorectal cancer (CRC) patients, and to evaluate the significance of the proteomic patterns in colorectal cancer staging...
  17. pmc ST13, a proliferation regulator, inhibits growth and migration of colorectal cancer cell lines
    Rui Bai
    Cancer Institute Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, The Second Affiliated Hospital School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 13:884-93. 2012
    ..This study aims at the role of ST13 in the proliferation and migration of CRC cells...
  18. ncbi request reprint Clinical and genetic characteristics of Chinese hereditary nonpolyposis colorectal cancer families
    Xu lin Wang
    Cancer Institute, The 2nd Affiliated Hospital, College of Medicine, Zhejiang University, 88 Jie Fang Road, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 12:4074-7. 2006
    ..To analyze the clinical characteristics of Chinese hereditary nonpolyposis colorectal cancer (HNPCC) families and to screen the germline mutations of human mismatch repair genes hMLH1 and hMSH2 in the probands...
  19. ncbi request reprint [Mutation detection of mismatch repair genes in hereditary nonpolyposis colorectal cancer by denaturing high-performance liquid chromatography]
    Yan Qin Huang
    Cancer Institute, 2nd Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
    Zhonghua Wai Ke Za Zhi 43:317-20. 2005
    ..To establish DHPLC method in detecting mutations of mismatch repair genes, hMLH1 and hMSH2, and to identify germline mutations of hMLH1 and hMSH2 in HNPCC kindreds fulfilling Chinese HNPCC criteria...
  20. ncbi request reprint [Knockdown of PLK1 mRNA by special siRNA]
    Gong Xing Chen
    Cancer Institute, The 2nd Affiliated Hospital, Medical College, Zhejiang University, Hangzhou 310009, China
    Yi Chuan 28:21-5. 2006
    ..The results showed that siRNA targeting PLK1 mRNA had effectively knocked PLK1 mRNA down in SW480 cell line. And a blended siRNAs held the best knockdown effect. The cell was blocked on the mitosis and growth...
  21. ncbi request reprint [Large genomic deletions of mismatch repair genes in Chinese patients with hereditary nonpolyposis colorectal cancer]
    Yan qin Haung
    Cancer Institute, Zhejiang University, Hangzhou, Zhejiang, 310014 PR China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 22:88-90. 2005
    ..To gain an insight into large genomic deletions in mismatch repair genes MSH2 and MLH1 in Chinese hereditary nonpolyposis colorectal cancer (HNPCC) patients in order to improve genetic detections of HNPCC kindreds...
  22. doi request reprint Secreted protein acidic and rich in cysteines-like 1 suppresses aggressiveness and predicts better survival in colorectal cancers
    Hanguang Hu
    School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
    Clin Cancer Res 18:5438-48. 2012
    ..The hypothesis that SPARCL1 reduces cancer invasiveness and predicts better survival in colorectal cancers (CRC) was investigated...
  23. doi request reprint MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility
    Liang Zhu
    Cancer Institute Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Zhejiang Province, China, The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, Zhejiang, China
    Med Oncol 29:1037-43. 2012
    ..The overexpression of miR-9 could also down-regulate α-catenin expression. These data suggest that miR-9 may potentially participate in the metastatic process of CRC though facilitating cell motility...
  24. doi request reprint Hepatoma-derived growth factor involved in the carcinogenesis of gastric epithelial cells through promotion of cell proliferation by Erk1/2 activation
    Jianshan Mao
    Cancer Institute, Second Affiliated Hospital and Education Ministry Key laboratory of Cancer Prevention and Intervention, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
    Cancer Sci 99:2120-7. 2008
    ....
  25. ncbi request reprint [Application of serum protein markers to distinguish familial adenomatous polyposis (FAP) and sporadic colorectal adenomas]
    Shan Rong Cai
    The 2nd Affiliated Hospital, Medical School, Zhejiang University, Hangzhou 310009, China
    Zhonghua Zhong Liu Za Zhi 31:192-5. 2009
    ..To screen out specifically-expressed serum protein markers in familial adenomatous polyposis (FAP) and to establish a serum protein fingerprint diagnostic model for distinguishing FAP from sporadic colorectal adenomas...
  26. ncbi request reprint Clinical significance of vascular endothelial growth factor expression and neovascularization in colorectal carcinoma
    Shu Zheng
    Cancer Institute, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 9:1227-30. 2003
    ..To clarify the association of vascular endothelial growth factor (VEGF) and microvascular density (MVD) expression with the angiogenesis and prognosis of colorectal cancer...
  27. pmc Discovering differential protein expression caused by CagA-induced ERK pathway activation in AGS cells using the SELDI-ProteinChip platform
    Zhen Ge
    Cancer Institute of Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang, China
    World J Gastroenterol 14:554-62. 2008
    ..To identify the protein expression differences related to the CagA-induced ERK pathway activation in AGS cells...
  28. pmc Doxorubicin-mediated radiosensitivity in multicellular spheroids from a lung cancer cell line is enhanced by composite micelle encapsulation
    Wen Hong Xu
    Department of Radiation Oncology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
    Int J Nanomedicine 7:2661-71. 2012
    ..The purpose of this study is to evaluate the efficacy of composite doxorubicinloaded micelles for enhancing doxorubicin radiosensitivity in multicellular spheroids from a non-small cell lung cancer cell line...
  29. ncbi request reprint Genetic characterization of Chinese hereditary non-polyposis colorectal cancer by DHPLC and multiplex PCR
    Ying Yuan
    Cancer Research Institute, 2nd Hospital, Zhejiang University School of Medicine, 88 Jie Fang Road, Hangzhou, 310009 PR China
    Jpn J Clin Oncol 34:660-6. 2004
    ..The aim of the present study was to identify the point mutations and large genomic deletions of hMLH1 and hMSH2 genes in 14 Chinese HNPCC families...
  30. ncbi request reprint [Induction of HSF1 expression and sporadic colorectal cancer]
    Yong Ming Fang
    The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 33:390-4. 2004
    ..To explore the activation of the signal transduction pathways related with the carcinogenesis of sporadic colon cancers...
  31. pmc Evaluation of ST13 gene expression in colorectal cancer patients
    Qing Hua Dong
    Cancer Institute, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 6:1170-5. 2005
    ..05). But there were no significant differences in the expression of ST13 as compared with different Dukes' stage, tumor differentiation grade, invasion depth, lymph node metastasis and disease-specific survival...
  32. ncbi request reprint Expression of ST13 in colorectal cancer and adjacent normal tissues
    Lin Bo Wang
    Department of Surgical Oncology, Sir Run Run Shaw Hospital, Medical College, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
    World J Gastroenterol 11:336-9. 2005
    ..To investigate the in situ expression of suppression of tumorigenecity 13 (ST13) mRNA in both colorectal cancer and adjacent normal tissues...
  33. ncbi request reprint [Ultrastructure and crystallin mutant molecular modeling of hereditary coralliform cataract]
    Wei Zhen Xu
    The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:243-7. 2005
    ..To observe the correlation of gammaD-crystallin P23T mutant with lens ultrastructure of the hereditary coralliform cataract...
  34. doi request reprint The dominant negative mutant Artemis enhances tumor cell radiosensitivity
    Hai Liu
    Cancer Institute, Zhejiang University School of Medicine, The Second Affiliated Hospital, Hangzhou, China
    Radiother Oncol 101:66-72. 2011
    ..Intervention with DNA double-strand break repair is an effective way to modulate tumor cell radiosensitivity. This study focused on the mutant Artemis fragment-enhanced radiosensitivity of human cervical cancer cells...
  35. ncbi request reprint [Effect of microRNA143 expression on cell proliferation in colonic carcinoma]
    Hong Liu
    Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
    Zhonghua Zhong Liu Za Zhi 30:498-501. 2008
    ..To investigate the effect of microRNA143 on cell proliferation and K-ras expression in colorectal carcinoma...
  36. doi request reprint Inhibition of apoptosis by downregulation of hBex1, a novel mechanism, contributes to the chemoresistance of Bcr/Abl+ leukemic cells
    Kefeng Ding
    Cancer Institute, Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang Province, Hangzhou, PR China
    Carcinogenesis 30:35-42. 2009
    ..These data provide evidence that expression of hBex1 in leukemic cells is a novel mechanism by which chemoresistance is achieved and suggests that hBex1 is a potential molecular target for the development of novel leukemia treatments...
  37. pmc Preoperatively molecular staging with CM10 ProteinChip and SELDI-TOF-MS for colorectal cancer patients
    Wen Hong Xu
    Cancer Institute, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 7:235-40. 2006
    ....
  38. ncbi request reprint [Alcohol drinking and colorectal cancer: a population-based prospective cohort study]
    Kun Chen
    Department of Epidemiology, College of Medicine, Zhejiang University, Hangzhou 310031, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 33:411-5. 2004
    ..To understand the incidence of colorectal cancer in population drinking or not and to validate the relationship between drinking and colorectal cancer...
  39. pmc Knockdown of OLA1, a regulator of oxidative stress response, inhibits motility and invasion of breast cancer cells
    Jia Wei Zhang
    Cancer Institute National Ministry of Education Key Laboratory of Cancer Prevention and Intervention, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 10:796-804. 2009
    ..These results suggest that knockdown of OLA1 inhibits breast cancer cell migration and invasion through a mechanism that involves the modulation of intracellular ROS levels...
  40. doi request reprint Detection of renal allograft dysfunction with characteristic protein fingerprint by serum proteomic analysis
    Minmin Wang
    The Kidney Disease Center, the First Affiliated Hospital of Medical College, Zhejiang University, 79 Qingchun Road, Hangzhou, China
    Int Urol Nephrol 43:1009-17. 2011
    ..Specific markers were detected in each group. Identification of these proteins may prove useful as diagnostic markers for allograft dysfunction and better to elucidate the mechanism of acute rejection...
  41. pmc Performance value of high risk factors in colorectal cancer screening in China
    Wen Meng
    Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 15:6111-6. 2009
    ..To analyze the performance value of high risk factors in population-based colorectal cancer (CRC) screening in China...
  42. ncbi request reprint Identification of the biomarkers for the prediction of efficacy in first-line chemotherapy of metastatic colorectal cancer patients using SELDI-TOF-MS and artificial neural networks
    Ying Yuan
    Department of Medical Oncology, China National Ministry of Education, China
    Hepatogastroenterology 59:2461-5. 2012
    ..There are no clinically useful markers that could predict the response to these regimens respectively. We aimed at identifying serum protein patterns which could predict the efficacy of chemotherapy...
  43. ncbi request reprint Effect of SNC19/ST14 gene overexpression on invasion of colorectal cancer cells
    Ke Feng Ding
    Surgery of Oncology, The Second Affiliated Hospital, School of Medicine, Zhejinag University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 11:5651-4. 2005
    ..To study the effect of SNC19/ST14 gene overexpression on invasion in vitro of colorectal cancer cells...
  44. ncbi request reprint Apoptosis induction with polo-like kinase-1 antisense phosphorothioate oligodeoxynucleotide of colon cancer cell line SW480
    Yu Fan
    Cancer Institute, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 11:4596-9. 2005
    ..To investigate the effects of polo-like kinase-1 (PLK1) antisense phosphorothioate oligodeoxynucleotide (ASODN) on apoptosis and cell cycle of human colon cancer cell line SW480...
  45. ncbi request reprint Cytidine deaminase APOBEC3B interacts with heterogeneous nuclear ribonucleoprotein K and suppresses hepatitis B virus expression
    Wei Zhang
    Second Affiliated Hospital, Cancer Institute, School of Medicine, Zhejiang University, Hangzhou 310009, China
    Cell Microbiol 10:112-21. 2008
    ..In addition, A3B protein may be a broad antiviral host factor. Thus, regulated A3B expression may contribute to non-cytolytic HBV clearance in vivo...
  46. pmc MicroRNAs up-regulated by CagA of Helicobacter pylori induce intestinal metaplasia of gastric epithelial cells
    Yongliang Zhu
    Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
    PLoS ONE 7:e35147. 2012
    ..These results indicate that miRNA-584 and miRNA-1290 interfere with cell differentiation and remodel the tissues. Thus, the miRNA pathway is a new pathogenic mechanism of CagA...
  47. ncbi request reprint Silymarin causes caspases activation and apoptosis in K562 leukemia cells through inactivation of Akt pathway
    Xian Zhong
    Cancer Institute, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
    Toxicology 227:211-6. 2006
    ..These findings suggest that silymarin could serve as a candidate for anti-leukemia drug...
  48. ncbi request reprint Special fasciculiform cataract caused by a mutation in the gammaD-crystallin gene
    Xingchao Shentu
    Eye Center, Affiliated Second Hospital, College of Medicine, Zhejiang University, Hangzhou, China
    Mol Vis 10:233-9. 2004
    ..To identify ultrastructure changes and genetic defects associated with a special fasciculiform autosomal dominant congenital cataract (ADCC) affecting a large Chinese family...
  49. pmc Comparative features of colorectal and gastric cancers with microsatellite instability in Chinese patients
    Yan Qin Huang
    Key Laboratory of Cancer Prevention and Intervention of Ministry of Education, Key Laboratory of Molecular Biology in Medical Science of Zhejiang Province, Cancer Institute, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 11:647-53. 2010
    ..The purpose of this study was to determine the unique and universal features of microsatellite instability-high (MSI-H) colorectal cancer (CRC) and MSI-H gastric cancer (GC) in the Chinese population...
  50. doi request reprint ChIP-seq and functional analysis of the SOX2 gene in colorectal cancers
    Xuefeng Fang
    Cancer Institute Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People s Republic of China
    OMICS 14:369-84. 2010
    ....
  51. doi request reprint CaMKII γ, a critical regulator of CML stem/progenitor cells, is a target of the natural product berbamine
    Ying Gu
    Department of Hematology, Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Hangzhou, China
    Blood 120:4829-39. 2012
    ....
  52. ncbi request reprint [Association of drinking water source and colorectal cancer incidence: a prospect cohort study]
    Kun Chen
    Department of Epidemiology, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310031, PR China
    Ai Zheng 23:550-4. 2004
    ..There is little prospect cohort study with person-years directly on the relative risks of different sources of drinking water for CRC...
  53. ncbi request reprint [Classification and diagnostic prediction of colorectal cancer using protein profiling of serum and bioinformatics]
    Yi Ding Chen
    Department of Oncology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 38:470-7. 2009
    ..To develop a bioinformatic tool and to use it to identify proteomic patterns in serum, distinguishing colorectal cancer from colorectal adenoma and healthy individuals...
  54. pmc Overexpression of Shp2 tyrosine phosphatase is implicated in leukemogenesis in adult human leukemia
    Rongzhen Xu
    Department of Hematology, Second Affiliated Hospital, School of Medicine, Cancer Institute, Zhejiang University, Zhejiang Academy of Medical Sciences, Hangzhou, Zhejiang 310009, China
    Blood 106:3142-9. 2005
    ..Based on these results, we propose that aberrantly increased expression of Shp2 may contribute, collaboratively with other factors, to leukemogenesis...
  55. pmc Induced pluripotent stem cell-related genes influence biological behavior and 5-fluorouracil sensitivity of colorectal cancer cells
    Zhong Shi
    Cancer Institute, Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Zhejiang Province, China
    J Zhejiang Univ Sci B 13:11-9. 2012
    ....
  56. ncbi request reprint Characterization of CagA variable region of Helicobacter pylori isolates from Chinese patients
    Yong Liang Zhu
    Department of Gastroenterology, Second Hospital of Zhejiang University College of Medicine, Hangzhou, China
    World J Gastroenterol 11:880-4. 2005
    ..To characterize the CagA variable region of Helicobacter pylori isolates from Chinese patients...
  57. doi request reprint Identification and characterization of a small inhibitory peptide that can target DNA-PKcs autophosphorylation and increase tumor radiosensitivity
    Xiaonan Sun
    Department of Radiation Oncology, Sir Run Run Shaw Hospital, Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, Hangzhou, China
    Int J Radiat Oncol Biol Phys 84:1212-9. 2012
    ..Here, we aimed to develop small inhibitory peptides that could specifically target DNA-PKcs autophosphorylation, a critical step for the enzymatic activation of the kinase in response to IR...
  58. doi request reprint MicroRNA-183 regulates Ezrin expression in lung cancer cells
    Guofu Wang
    The 2nd Affiliated Hospital, School of Medicine, College of Life Sciences, Zhejiang University, Hangzhou, China
    FEBS Lett 582:3663-8. 2008
    ..We also found that miR-183 could regulate the expression of other genes involved in migration and invasion. Taken together, our findings demonstrated a new role and regulatory mechanism of miR-183 in controlling cancer metastasis...
  59. doi request reprint Impact of a laparoscopic resection on the quality of life in rectal cancer patients: results of 135 patients
    Jun Li
    Department of Surgical Oncology, Second Affiliated Hospital, and The Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Zhejiang University College of Medicine, No 88 Jiefang Road, Hangzhou, 310009 Zhejiang Province, PR China
    Surg Today 40:917-22. 2010
    ..To investigate the impact of a laparoscopic resection on the quality of life in rectal cancer patients...
  60. pmc Clinical significance of K-ras and BRAF mutations in Chinese colorectal cancer patients
    Hong Shen
    Department of Oncology, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 17:809-16. 2011
    ..To identify and assess mutations in the K-ras and BRAF genes in a cohort of Chinese patients with colorectal cancer (CRC) for their association with various clinicopathological parameters and prognosis...
  61. doi request reprint Potent antitumor activity of double-regulated oncolytic adenovirus-mediated ST13 for colorectal cancer
    De Bin Yu
    Xinyuan Institute of Medicine and Biotechnology, Zhejiang Sci Tech University, Hangzhou, China
    Cancer Sci 100:678-83. 2009
    ..To further identify the antitumor effects of SG500-ST13 on HCT116 xenografts in Balb/c nude mice, the induction of cell death was assessed by hematoxylin-eosin staining. Immunohistochemical study was also carried out...
  62. pmc Proteomic analysis of primary colon cancer-associated fibroblasts using the SELDI-ProteinChip platform
    Zhan Huai Wang
    Cancer Institute, The Second Affiliated Hospital School of Medicine, Zhejiang University, Hangzhou, China
    J Zhejiang Univ Sci B 13:159-67. 2012
    ..However, the unique protein expression of CAFs has not been fully elucidated. This study aims to investigate the characterizations of colon CAFs by comparing the differential protein expression between CAFs and normal fibroblasts...
  63. pmc SPARCL1, Shp2, MSH2, E-cadherin, p53, ADCY-2 and MAPK are prognosis-related in colorectal cancer
    Shu jing Yu
    Department of Radiation Oncology, The Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 17:2028-36. 2011
    ..To investigate the expression of markers that are correlated with the prognosis of colorectal cancer (CRC) patients...
  64. pmc Epidermal growth factor receptor-regulated miR-125a-5p--a metastatic inhibitor of lung cancer
    Guofu Wang
    Department of Respiratory Disease, Zhejiang Hospital, Hangzhou, China
    FEBS J 276:5571-8. 2009
    ..Taken together, our results provide compelling evidence that miR-125a-5p, an epidermal growth factor-signaling-regulated miRNA, may function as a metastatic suppressor...
  65. ncbi request reprint Clinical features of familial adenomas polyps in Chinese and establishment of its immortal lymphocyte cell lines
    Shan Rong Cai
    Cancer Institute, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 13:2858-61. 2007
    ..To reserve the rare Chinese familial adenomas polyp (FAP) family resource and to investigate the clinical features of FAP in Chinese for its diagnosis...
  66. ncbi request reprint Association of human APOBEC3 cytidine deaminases with the generation of hepatitis virus B x antigen mutants and hepatocellular carcinoma
    Rongzhen Xu
    Second Affiliated Hospital, Cancer Institute, School of Medicine, Zhejiang University, Hangzhou, China
    Hepatology 46:1810-20. 2007
    ..Deregulated expression of A3B in liver tissues may also have the potential to promote genetic instability and tumorigenesis...
  67. pmc Quantitative real-time RT-PCR detection for CEA, CK20 and CK19 mRNA in peripheral blood of colorectal cancer patients
    Dong Xu
    Cancer Institute, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 7:445-51. 2006
    ..Our study indicates that quantitative real-time RT-PCR detection for CEA, CK20 and CK19 mRNA in peripheral blood is a valuable tool for monitoring early stage dissemination of CRC cells in blood circulation...
  68. ncbi request reprint [SNC19/ST14 gene transfection and expression influence the biological behavior of colorectal cancer cells]
    Li Feng Sun
    Cancer Institute, The Second Affiliated Hospital, Medical College of Zhejiang University, Hangzhou 310009, China
    Zhonghua Yi Xue Za Zhi 84:843-8. 2004
    ..To study the effect of SNC19/ST14 gene transfection and expression into colorectal cancer cells on biological behavior...
  69. ncbi request reprint [Diagnostic application of serum protein pattern and artificial neural network software in breast cancer]
    Yue Hu
    Cancer Institute, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310 009, P R China
    Ai Zheng 24:67-71. 2005
    ....
  70. ncbi request reprint [Mutational studies of adenomatous polyposis coli gene in carcinomas from patients with hereditary non-polyposis colorectal cancers]
    Jian Huang
    Department of Oncology, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310009 PR China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20:196-9. 2003
    ..To analyze the mutational features of adenomatous polyposis coli (APC) gene and to explore the effect of mismatch repair (MMR) deficiency on its mutations in hereditary non-polyposis colorectal cancers (HNPCC)...
  71. ncbi request reprint Artificial neural networks analysis of surface-enhanced laser desorption/ionization mass spectra of serum protein pattern distinguishes colorectal cancer from healthy population
    Yi Ding Chen
    Department of Oncology, Second Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, People s Republic of China
    Clin Cancer Res 10:8380-5. 2004
    ..We developed and evaluated a proteomic approach for the simultaneous detection and analysis of multiple proteins for distinguishing individuals with colorectal cancer from healthy individuals...
  72. ncbi request reprint [Study on post-translational processing and active forms of the novel metastasis-associated protein SNC19]
    Ying Shi
    The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:38-42. 2005
    ..To investigate the relationship between SNC19 protein and cancer metastasis...
  73. ncbi request reprint Inducible nitric oxide synthase expression is related to angiogenesis, bcl-2 and cell proliferation in hepatocellular carcinoma
    Jia Ping Peng
    Cancer Institute, College of Medicine, Zhejiang University, Hangzhou, 310009, China
    J Zhejiang Univ Sci 4:221-7. 2003
    ..The present findings suggested that iNOS expression was significantly associated with angiogenesis, bcl-2 and cell proliferation of HCC...
  74. ncbi request reprint Study on interleukin-18 gene transfer into human breast cancer cells to prevent tumorigenicity
    Ming Yong Han
    Cancer Institute, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci 5:472-6. 2004
    ..The Bcap37 cells transduced with IL-18 gene may be used as breast cancer vaccine...
  75. ncbi request reprint [Effect of Kanglaite injection oncyclooxygenase activity in lung carcinoma A549 cell]
    Qing Hua Dong
    The 2nd Affiliated Hospital of Zhejiang University, Cancer Institute, Zhejiang University, Hangzhou 310016, China
    Zhongguo Zhong Yao Za Zhi 30:1621-3, 1633. 2005
    ..To study the effect of Kanglaite injection on cyclooxygenase activity in lung carcinoma A549 cells...
  76. ncbi request reprint Autosomal dominant coralliform cataract related to a missense mutation of the gammaD-crystallin gene
    Wei Zhen Xu
    Cancer Institute, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
    Chin Med J (Engl) 117:727-32. 2004
    ..About 25% of all cases are due to genetic defects. We identified autosomal dominant congenital coralliform cataracts-related genetic defect in a four-generation Chinese family...
  77. ncbi request reprint [Combined detection of CEA mRNA and CK 19 mRNA in peripheral blood cells of patients with lung cancer]
    Xu fen Li
    Department of Oncology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China
    Zhonghua Zhong Liu Za Zhi 26:382-4. 2004
    ..To investigate the expression of CEA mRNA and CK(19) mRNA in peripheral blood cells of patients with lung cancer and evaluate its clinical significance...
  78. doi request reprint Influences of laparoscopic resection on expressions of metastasis genes in colorectal cancer: report of microarray analysis and literature review
    Jun Li
    Department of Social Oncology, Zhejiang University College of Medicine, Hangzhou, China
    Hepatogastroenterology 58:1975-82. 2011
    ..To comprehensively understand the influence of laparoscopic resection on expressions of metastasis related genes in colorectal cancer by microarray...
  79. pmc Expression patterns of non-coding spliced transcripts from human endogenous retrovirus HERV-H elements in colon cancer
    Qiaoyi Liang
    Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
    PLoS ONE 7:e29950. 2012
    ..Up-regulation of the most abundant H family human endogenous retrovirus (HERV-H), especially env-related transcripts, correlates with colon cancer. However, expression pattern of spliced non-coding transcripts of HERV-H is not clear...
  80. ncbi request reprint CYP1A1, GSTs and mEH polymorphisms and susceptibility to esophageal carcinoma: study of population from a high- incidence area in north China
    Li Dong Wang
    Cancer Institute, Zhejiang University, Hangzhou, Zheijiang Province, China
    World J Gastroenterol 9:1394-7. 2003
    ..To characterize cytochrome P4501A1 (CYP1A1), glutathione S-transferases (GSTs) and microsomal epoxide hydrolase (mEH) polymorphisms in Chinese esophageal cancer patients...
  81. ncbi request reprint Somatic mutations of APC gene in carcinomas from hereditary non-polyposis colorectal cancer patients
    Jian Huang
    Department of Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 10:834-6. 2004
    ..To investigate the mutational features of adenomatous polyposis coli (APC) gene and its possible arising mechanism in hereditary non-polyposis colorectal cancers (HNPCC)...
  82. ncbi request reprint A fusion protein of conotoxin MVIIA and thioredoxin expressed in Escherichia coli has significant analgesic activity
    Jinbiao Zhan
    Department of Biochemistry, Zhejiang University Medical School, 353 Yan An Road, Hangzhou 310006, PR China
    Biochem Biophys Res Commun 311:495-500. 2003
    ..6 mg/kg, marked analgesia was observed. The analgesic effects (elevated pain thresholds) were dose-dependent and the biological half-life of the fusion toxin was approximately 1.6 h...
  83. ncbi request reprint Expression of ricin A chain and ricin A chain-KDEL in Escherichia coli
    Jinbiao Zhan
    Department of Biochemistry, Zhejiang University Medical School, 353 Yan An Road, Hangzhou 310006, PR China
    Protein Expr Purif 34:197-201. 2004
    ..RTA-KDEL was somewhat more cytotoxic than RTA itself in the different cell lines. The results suggest that rRTA-KDEL may be useful for the synthesis of more potent immunotoxins...
  84. ncbi request reprint A trans-Golgi network retention signal YQRL fused to ricin A chain significantly enhances its cytotoxicity
    Jinbiao Zhan
    Department of Biochemistry, Zhejiang University Medical School, 353 Yan An Road, Hangzhou 310006, PR China
    Biochem Biophys Res Commun 313:1053-7. 2004
    ..The results indicate that addition of a TGN retention signal YQRL to the C-terminus of RTA can markedly increase its cytotoxicity, suggesting TGN may play an important role in the intracellular routing and translocation of RTA...
  85. ncbi request reprint [Expression and recombination mechanism of SNC73 (IgHalpha1) in human epithelial cancer cell line]
    Li Yi Geng
    Cancer Institute, Zhejiang University, Hangzhou 310009, China
    Zhonghua Yi Xue Za Zhi 83:1493-6. 2003
    ..To study if the gene SNC73 (IgHalpha1) is expressed in human epithelial cancer cell line and to interpret the recombination mechanism...
  86. ncbi request reprint Effective induction of therapeutic antitumor immunity by dendritic cells coexpressing interleukin-18 and tumor antigen
    Dajing Xia
    Institute of Immunology, Zhejiang University, 310031, Hangzhou, P R China
    J Mol Med (Berl) 81:585-96. 2003
    ..These results indicate that immunization with DC vaccine coexpressing Th1 cytokine IL-18 and tumor antigen gene may be an effective strategy for a successful therapeutic vaccination...
  87. ncbi request reprint Reduction of the incidence and mortality of rectal cancer by polypectomy: a prospective cohort study in Haining County
    Shu Zheng
    Cancer Institute, Zhejiang University, 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 8:488-92. 2002
    ....
  88. ncbi request reprint Helicobacter pylori infection and gastric cancer: evidence from a retrospective cohort study and nested case-control study in China
    Run tian Wang
    Health Science Center, Peking University, Beijing, China
    World J Gastroenterol 8:1103-7. 2002
    ..To explore the association between Helicobacter pylori (Hp) infection and risk of gastric cancer in China...
  89. ncbi request reprint Nested case-control study on the risk factors of colorectal cancer
    Kun Chen
    Department of Epidemiology, Zhejiang University School of Public Health, Hangzhou, 310006 Zhejiang Province, China
    World J Gastroenterol 9:99-103. 2003
    ..To investigate the risk factors of colon cancer and rectal cancer...
  90. ncbi request reprint Cluster randomization trial of sequence mass screening for colorectal cancer
    Shu Zheng
    Cancer Institute, Medicine College, Zhejiang University, Hangzhou, Zhejiang, Peoples Republic of China
    Dis Colon Rectum 46:51-8. 2003
    ....
  91. ncbi request reprint [Overexpression of S3 ribosomal protein gene is involved in drug resistance in K562/DOX cells]
    Ning Xi Zhu
    Zhejiang Provincial Hospital of Traditional Chinese Medicine, Hangzhou 310006, China
    Zhonghua Xue Ye Xue Za Zhi 24:141-3. 2003
    ..To investigate the effect of overexpression of S3 ribosomal protein (S3rp) gene on the resistance of leukemia cell to antitumor drugs...
  92. ncbi request reprint Expression of a novel immunoglobulin gene SNC73 in human cancer and non-cancerous tissues
    Jian Bin Hu
    Department of Radiation Oncology, Sir Run Run Shaw Hospital, Zhejiang University Medical College, Hangzhou, Zhejiang Province, China
    World J Gastroenterol 9:1054-7. 2003
    ..To investigate the expression of immunoglobulin gene SNC73 in malignant tumors and non-cancerous normal tissues...
  93. ncbi request reprint [Subcutaneous transplantation of microencapsulated Chinese hamster ovary (CHO) cells/pcDNA 3.1/mIL-12 and subcutaneous transplantation of microencapsulated CHO/pcDNA3.1/mIL-12 combined with 5-fluoro-uracil in treatment of tumor-burdened mice]
    Yue Long Pan
    Cancer Institute, Zhejiang University, Hangzhou 310009, China
    Zhonghua Yi Xue Za Zhi 83:51-4. 2003
    ..1/mIL-12 and subcutaneous transplantation of microencapsulated CHO/pcDNA3.1/mIL-12 combined with 5-fluoro-uracilum (5-FU) in treatment of tumor-burdened mice...
  94. ncbi request reprint [The microencapsulated genetic engineering cells: a new platform on treatment of cancer instead of genetic engineering drugs]
    Yuelong Pan
    Cancer Institute, Zhejiang University, Hangzhou 310009
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 20:345-7. 2003
    ..This article reviews and summarizes the advantages, possible problems and solution and the feasibility of using microencapsulated genetic engineering cells in the treatment of cancer...
  95. ncbi request reprint [Expression of a novel immunoglobulin gene SNC73 in human cancer and its significance]
    Jianbin Hu
    Cancer Institute, Zhejiang University, Hangzhou 310009, China
    Zhonghua Zhong Liu Za Zhi 24:38-40. 2002
    ..To investigate the expression of a new immunoglobulin gene SNC73 in malignant tumor and normal tissue and its significance...
  96. ncbi request reprint [Relationship between organochlorine pollution in soil and rice and the incidence of colorectal cancer in Jiashan county, Zhejiang province]
    Kun Chen
    Department of Epidemiology, School of Medicine Zhejiang University, Hangzhou 310006, China
    Zhonghua Liu Xing Bing Xue Za Zhi 25:479-83. 2004
    ..To study the relationship between organochlorine and colorectal cancer...
  97. doi request reprint Potent antitumor efficacy of ST13 for colorectal cancer mediated by oncolytic adenovirus via mitochondrial apoptotic cell death
    Min Yang
    Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Hum Gene Ther 19:343-53. 2008
    ..In summary, overexpressed ST13 as mediated by oncolytic adenovirus could exert potent antitumor activity via the intrinsic apoptotic pathway and has the potential to become a novel therapeutic for colorectal cancer gene therapy...
  98. ncbi request reprint [Influence of microencapsulated ovary cells modified with maspin gene on the microvessel density and lung metastasis of breast carcinoma]
    Yue Long Pan
    Department of Tumor, Hangzhou First People s Hospital, Hangzhou 310006, China
    Zhonghua Yi Xue Za Zhi 88:92-5. 2008
    ..To observe the inhibition of maspin on the angiogenesis in tumor and lung metastasis of breast carcinoma and the feasibility of treatment of tumor by microencapsulated transgene cells in vivo...
  99. ncbi request reprint Alcohol drinking and colorectal cancer: a population-based prospective cohort study in China
    Kun Chen
    Department of Epidemiology and Health Statistics, Zhejiang University School of Medicine, Hangzhou, China
    Eur J Epidemiol 20:149-54. 2005
    ..To asses the association between alcohol consumption and the risk of colorectal cancer (CRC) in the Chinese population...
  100. ncbi request reprint [protein toxins and their medical applications]
    Jin Biao Zhan
    Department of Biochemistry and Molecular Biology, College of Medicine, Zhejiang University, Hangzhou 310006, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:197-200. 2005
  101. pmc Influence of CO2 pneumoperitoneum on intracellular pH and signal transduction in cancer cells
    Li Ping Cao
    Department of Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    J Zhejiang Univ Sci B 6:650-5. 2005
    ..The authors studied the influence of CO(2) pneumoperitoneum on intracellular pH and signal transduction arising from cancer cell multiplication in laparoscopic tumor operation...