Shu Zheng

Summary

Affiliation: Zhejiang University
Country: China

Publications

  1. ncbi Protein interaction analysis of ST14 domains and their point and deletion mutants
    Weiting Ge
    College of Life Science, Zhejiang University, Hangzhou 310029, China
    J Biol Chem 281:7406-12. 2006
  2. pmc microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer
    Lijing Zhang
    Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Prince of Wales Hospital, Li Ka Shing Institute of Health Sciences, Shenzhen Research Institute, The Chinese University of Hong Kong, Sha Tin, Hong Kong, China
    Mol Cancer 13:124. 2014
  3. doi Prognostic and therapeutic significance of ribonucleotide reductase small subunit M2 in estrogen-negative breast cancers
    Hang Zhang
    Cancer Institute, Second Affiliated Hospital, Zhejiang University School of Medicine, 310009 Hangzhou, Zhejiang, China
    BMC Cancer 14:664. 2014
  4. pmc Wnt modulates MCL1 to control cell survival in triple negative breast cancer
    Lixin Yang
    Department of Molecular Pharmacology, Beckman Research Institute, City of Hope National Medical Center, Beckman Building, Room 4117, 1500 East Duarte Road, Duarte, CA 91010, USA
    BMC Cancer 14:124. 2014
  5. pmc Expression patterns of non-coding spliced transcripts from human endogenous retrovirus HERV-H elements in colon cancer
    Qiaoyi Liang
    Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
    PLoS ONE 7:e29950. 2012
  6. pmc Osteopontin-enhanced hepatic metastasis of colorectal cancer cells
    Jianjin Huang
    Department of Medical Oncology, Second Affiliated Hospital, Medical School of Zhejiang University, Hangzhou, China
    PLoS ONE 7:e47901. 2012
  7. pmc Identification and detection of a novel human endogenous retrovirus-related gene, and structural characterization of its related elements
    Qiaoyi Liang
    Cancer Institute, Second Affiliated Hospital and Ministry of Education Key Laboratory of Cancer Prevention and Intervention, Zhejiang University School of Medicine, Hangzhou China
    Genet Mol Biol 32:704-8. 2009
  8. ncbi [Proliferative and invasive effects of inhibitors of kinase 4(P15(ink4b) and P16(ink4a)/CDKN2) gene activation on RKO human colorectal cancer cells]
    Xiaoming Fang
    Cancer Institute, Zhejiang University School of Medicine, Hangzhou 310009, China
    Zhonghua Wei Chang Wai Ke Za Zhi 17:31-5. 2014
  9. ncbi [Exploration of translational medicine research in metastasis and invasion of malignant tumors]
    Shu Zheng
    Cancer Institute Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
    Zhonghua Wei Chang Wai Ke Za Zhi 17:1-5. 2014
  10. ncbi [Translational medicine of colorectal cancer]
    Shu Zheng
    Zhejiang University School of Medicine, Hangzhou, China
    Zhonghua Wei Chang Wai Ke Za Zhi 16:4-7. 2013

Collaborators

  • Su zhan Zhang
  • Qi Dong
  • Ying Yuan
  • Ke Feng Ding
  • Rongzhen Xu
  • Biaoyang Lin
  • Jian Huang
  • Yongliang Zhu
  • Yi Ding Chen
  • Li Feng Sun
  • Xun Hu
  • Jiang Cao
  • Dan Li
  • Hai Liu
  • Jun Li
  • Kun Chen
  • Ling Ding
  • Qin Du
  • Bin Liu
  • Shan Rong Cai
  • Jie kai Yu
  • Yan Qin Huang
  • Qiaoyi Liang
  • Xian Zhong
  • Jia Ping Peng
  • Jinbiao Zhan
  • Wen Hong Xu
  • Weiting Ge
  • Hang Zhang
  • Rui Bai
  • Jiaofang Shao
  • Xuefeng Fang
  • Hong Shen
  • Yue Hu
  • Jia Wei Zhang
  • Guofu Wang
  • Yun Yen
  • Xiyong Liu
  • Huarong Chen
  • Zhong Shi
  • Yue Long Pan
  • Han Guang Hu
  • Zefeng Xu
  • Dong Xu
  • Li Yi Geng
  • Hanguang Hu
  • Jianshan Mao
  • Ying Gu
  • Wei Zhen Xu
  • Xu fen Li
  • Qi Chun Wei
  • Min Yang
  • Zhen Ge
  • Wen Zhi Jiang
  • Lijing Zhang
  • Yanqin Huang
  • Lixin Yang
  • Xiaoming Fang
  • Yong mao Song
  • Zhixuan Fu
  • Ze Feng Xu
  • Sofia Loera
  • Jia Yi Ding
  • Jiaping Peng
  • Peiguo Chu
  • Yong Ming Fang
  • Zhi Xuan Fu
  • Tao Wang
  • Liang Zhu
  • Zhan Huai Wang
  • Xiaonan Sun
  • Dasong Hua
  • Ke Yao
  • Shu jing Yu
  • Minmin Wang
  • Lisha Li
  • Wei Ting Ge
  • Lun Zhou
  • Wei Yu
  • Keyi Wang
  • Yongming Fang
  • Jiekai Yu
  • Jiawei Zhang
  • Jiayi Ding
  • De Bin Yu
  • Wen Meng
  • Xin Yuan Liu
  • Weimin Mao
  • Mingyong Han
  • Wei Zhang

Detail Information

Publications130 found, 100 shown here

  1. ncbi Protein interaction analysis of ST14 domains and their point and deletion mutants
    Weiting Ge
    College of Life Science, Zhejiang University, Hangzhou 310029, China
    J Biol Chem 281:7406-12. 2006
    ..Finally, homology modeling studies suggested that TMEFF1 might form a complex with ST14 by an interaction between epidermal growth factor and CUB domains...
  2. pmc microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer
    Lijing Zhang
    Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Prince of Wales Hospital, Li Ka Shing Institute of Health Sciences, Shenzhen Research Institute, The Chinese University of Hong Kong, Sha Tin, Hong Kong, China
    Mol Cancer 13:124. 2014
    ..miR-139-5p was identified to be significantly down-regulated in colon tumor tissues by miRNA array. We aimed to clarify its biological function, molecular mechanisms and direct target gene in colorectal cancer (CRC)...
  3. doi Prognostic and therapeutic significance of ribonucleotide reductase small subunit M2 in estrogen-negative breast cancers
    Hang Zhang
    Cancer Institute, Second Affiliated Hospital, Zhejiang University School of Medicine, 310009 Hangzhou, Zhejiang, China
    BMC Cancer 14:664. 2014
    ..Ribonucleotide reductase (RR) is an essential enzyme involved in DNA synthesis. We hypothesized that RR subunit M2 (RRM2) might be a novel prognostic and predictive biomarker for estrogen receptor (ER)-negative breast cancers...
  4. pmc Wnt modulates MCL1 to control cell survival in triple negative breast cancer
    Lixin Yang
    Department of Molecular Pharmacology, Beckman Research Institute, City of Hope National Medical Center, Beckman Building, Room 4117, 1500 East Duarte Road, Duarte, CA 91010, USA
    BMC Cancer 14:124. 2014
    ..Therefore, we directed our focus on identifying the WNT ligand and its underlying mechanism in TNBC cells...
  5. pmc Expression patterns of non-coding spliced transcripts from human endogenous retrovirus HERV-H elements in colon cancer
    Qiaoyi Liang
    Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
    PLoS ONE 7:e29950. 2012
    ..Up-regulation of the most abundant H family human endogenous retrovirus (HERV-H), especially env-related transcripts, correlates with colon cancer. However, expression pattern of spliced non-coding transcripts of HERV-H is not clear...
  6. pmc Osteopontin-enhanced hepatic metastasis of colorectal cancer cells
    Jianjin Huang
    Department of Medical Oncology, Second Affiliated Hospital, Medical School of Zhejiang University, Hangzhou, China
    PLoS ONE 7:e47901. 2012
    ..OPN plays a significant role in CRC metastasis to liver through interaction with its receptors in hepatocytes, decreased homotypic adhesion, and enhanced heterotypic adhesion...
  7. pmc Identification and detection of a novel human endogenous retrovirus-related gene, and structural characterization of its related elements
    Qiaoyi Liang
    Cancer Institute, Second Affiliated Hospital and Ministry of Education Key Laboratory of Cancer Prevention and Intervention, Zhejiang University School of Medicine, Hangzhou China
    Genet Mol Biol 32:704-8. 2009
    ..Further analysis of these elements revealed that all are structurally incomplete and only five exert transcriptional activity. The results presented here recommend further investigation into a potentially functional HERV-H-related ncRNA...
  8. ncbi [Proliferative and invasive effects of inhibitors of kinase 4(P15(ink4b) and P16(ink4a)/CDKN2) gene activation on RKO human colorectal cancer cells]
    Xiaoming Fang
    Cancer Institute, Zhejiang University School of Medicine, Hangzhou 310009, China
    Zhonghua Wei Chang Wai Ke Za Zhi 17:31-5. 2014
    ..To explore the proliferation and invasive effects of inhibitors of kinase 4(INK4)(P15(ink4b) and P16(ink4a)/CDKN2) gene protein activation on RKO human colorectal cell in vivo and in vitro...
  9. ncbi [Exploration of translational medicine research in metastasis and invasion of malignant tumors]
    Shu Zheng
    Cancer Institute Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
    Zhonghua Wei Chang Wai Ke Za Zhi 17:1-5. 2014
    ..It will be the new era for cancer prevention and intervention in translational medicine area. ..
  10. ncbi [Translational medicine of colorectal cancer]
    Shu Zheng
    Zhejiang University School of Medicine, Hangzhou, China
    Zhonghua Wei Chang Wai Ke Za Zhi 16:4-7. 2013
    ..Based on the concept of micro environment, molecular targeted drugs to interfere with metastasis and invasion and new concepts of surgical resection margin and neoadjuvant therapy will gain recognition from clinicians...
  11. pmc A giant hemolymphangioma of the pancreas in a 20-year-old girl: a report of one case and review of the literature
    Li Feng Sun
    Department of Surgical Oncology, The Second Affiliated Hospital, College of Medicine, Zhejinag University, Hangzhou Zhejiang 310009, PR China
    World J Surg Oncol 7:31. 2009
    ..Hemolymphangioma of the pancreas is a very rare benign tumor. There were only six reports of this disease until December 2008. Herein, we report a case of giant hemolymphangioma of the pancreas in a 20-year-old girl...
  12. pmc The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis
    Xuefeng Fang
    Swedish Neuroscience Institute, Swedish Medical Center, Seattle, WA 98122, USA
    BMC Genomics 12:11. 2011
    ..SOX2 appears to re-activate in several human cancers including glioblastoma multiforme (GBM), however, the detailed response program of SOX2 in GBM has not yet been defined...
  13. ncbi Continuous release of interleukin 12 from microencapsulated engineered cells for colon cancer therapy
    Shu Zheng
    Cancer Institute, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 9:951-5. 2003
    ..To explore the anti-tumor immunity against CT26 colon tumor of the microencapsulated cells modified with murine interleukine-12 (mIL-12) gene...
  14. ncbi [Challenge and opportunity in prevention and treatment of colorectal cancer in China]
    Shu Zheng
    The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 33:375-8. 2004
  15. pmc Hereditary colorectal cancer in china
    Zheng Shu
    Cancer Institute, Second Affiliated Hospital, Zhejiang University, Hangzhou, PR China
    Hered Cancer Clin Pract 3:155-64. 2005
    ..Total resection of the colon and rectum is necessary in FAP patients. For unresectable duodenal polyps, chemopreventive agents may be used...
  16. doi The novel human endogenous retrovirus-related gene, psiTPTE22-HERV, is silenced by DNA methylation in cancers
    Qiaoyi Liang
    Cancer Institute, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
    Int J Cancer 127:1833-43. 2010
    ..These results suggest psiTPTE22-HERV is regulated epigenetically by DNA methylation. Our study paved the way for further study on an interesting HERV-related human-specific gene, which is silenced in cancers by DNA methylation...
  17. doi Secreted protein acidic and rich in cysteines-like 1 suppresses aggressiveness and predicts better survival in colorectal cancers
    Hanguang Hu
    School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
    Clin Cancer Res 18:5438-48. 2012
    ..The hypothesis that SPARCL1 reduces cancer invasiveness and predicts better survival in colorectal cancers (CRC) was investigated...
  18. pmc Expression of SNC73, a transcript of the immunoglobulin alpha-1 gene, in human epithelial carcinomas
    Li Yi Geng
    Cancer Institute, Zhejiang University School of Medicine, The Second Affiliated Teaching Hospital, 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 13:2305-11. 2007
    ..To investigate the expression of SNC73, a trans-cript of the immunoglobulin alpha-1 gene (IgA1-H chain), in human epithelia-derived tumor cells...
  19. ncbi Honokiol: a potent chemotherapy candidate for human colorectal carcinoma
    Fei Chen
    Cancer Institute, Second Affiliated Hospital of Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 10:3459-63. 2004
    ..To investigate the anticancer activity of honokiol on RKO, a human colorectal carcinoma cell line in vitro and in vivo, and to evaluate its possible use in clinic...
  20. ncbi The Helicobacter pylori virulence factor CagA promotes Erk1/2-mediated Bad phosphorylation in lymphocytes: a mechanism of CagA-inhibited lymphocyte apoptosis
    Yongliang Zhu
    Department of Gastroenterology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
    Cell Microbiol 9:952-61. 2007
    ..Our results reveal that CagA, to some extent like IL-3, can enhance lymphocytes' ability to evade apoptosis through phosphorylation of Bad. This may account, at least in part, for the ability of CagA to promote lymphomagenesis...
  21. doi Hepatoma-derived growth factor involved in the carcinogenesis of gastric epithelial cells through promotion of cell proliferation by Erk1/2 activation
    Jianshan Mao
    Cancer Institute, Second Affiliated Hospital and Education Ministry Key laboratory of Cancer Prevention and Intervention, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
    Cancer Sci 99:2120-7. 2008
    ....
  22. ncbi [Comparison of clinical and genetic phenotypes between Chinese and Korean hereditary nonpolyposis colorectal cancer families]
    Hong Shen
    Department of Oncology, 2nd Hospital of Zhejiang University College of Medicine, Hangzhou, Zhejiang, 310009 People s Republic of China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 25:326-30. 2008
    ..To compare the clinical and genetic features between Chinese and Korean hereditary nonpolyposis colorectal cancer (HNPCC) families...
  23. doi Frequent epigenetic silencing of PCDH10 by methylation in human colorectal cancer
    Xian Zhong
    Cancer Institute Key Laboratory for Cancer Intervention and Prevention, China National Ministry of Education, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
    J Cancer Res Clin Oncol 139:485-90. 2013
    ..Recently, methylation of PCDH10 was reported to be associated with multiple hematologic malignancies as well as some solid tumors. Whether the down-regulation of PCDH10 happens in CRC remains unknown...
  24. ncbi [Preoperative molecular staging of colorectal cancers by CM10 ProteinChip and SELDI-TOF-MS analysis]
    Wen Hong Xu
    Department of Oncology, Cancer Institute, Clinical Laboratory, Second Affiliated Hospital of Zhejiang University College of Medicine, Hangzhou 310009, China
    Zhonghua Zhong Liu Za Zhi 28:753-7. 2006
    ..To detect the serum proteomic patterns by using SELDI-TOF-MS and CM10 ProteinChip techniques in colorectal cancer (CRC) patients, and to evaluate the significance of the proteomic patterns in colorectal cancer staging...
  25. doi Performance of a colorectal cancer screening protocol in an economically and medically underserved population
    Shan Rong Cai
    Cancer Institute, Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Zhejiang Province, PR China
    Cancer Prev Res (Phila) 4:1572-9. 2011
    ..Men had a higher prevalence of advanced neoplasm than women. Results indicate that combining FITs and HRFQ as primary screening methods is an efficient CRC screening strategy in economically and medically underserved populations...
  26. ncbi [Mutation detection of mismatch repair genes in hereditary nonpolyposis colorectal cancer by denaturing high-performance liquid chromatography]
    Yan Qin Huang
    Cancer Institute, 2nd Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
    Zhonghua Wai Ke Za Zhi 43:317-20. 2005
    ..To establish DHPLC method in detecting mutations of mismatch repair genes, hMLH1 and hMSH2, and to identify germline mutations of hMLH1 and hMSH2 in HNPCC kindreds fulfilling Chinese HNPCC criteria...
  27. pmc Clinical and genetic characteristics of Chinese hereditary nonpolyposis colorectal cancer families
    Xu lin Wang
    Cancer Institute, The 2nd Affiliated Hospital, College of Medicine, Zhejiang University, 88 Jie Fang Road, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 12:4074-7. 2006
    ..To analyze the clinical characteristics of Chinese hereditary nonpolyposis colorectal cancer (HNPCC) families and to screen the germline mutations of human mismatch repair genes hMLH1 and hMSH2 in the probands...
  28. pmc ST13, a proliferation regulator, inhibits growth and migration of colorectal cancer cell lines
    Rui Bai
    Cancer Institute Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, The Second Affiliated Hospital School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 13:884-93. 2012
    ..This study aims at the role of ST13 in the proliferation and migration of CRC cells...
  29. ncbi [Large genomic deletions of mismatch repair genes in Chinese patients with hereditary nonpolyposis colorectal cancer]
    Yan qin Haung
    Cancer Institute, Zhejiang University, Hangzhou, Zhejiang, 310014 PR China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 22:88-90. 2005
    ..To gain an insight into large genomic deletions in mismatch repair genes MSH2 and MLH1 in Chinese hereditary nonpolyposis colorectal cancer (HNPCC) patients in order to improve genetic detections of HNPCC kindreds...
  30. ncbi [Knockdown of PLK1 mRNA by special siRNA]
    Gong Xing Chen
    Cancer Institute, The 2nd Affiliated Hospital, Medical College, Zhejiang University, Hangzhou 310009, China
    Yi Chuan 28:21-5. 2006
    ..The results showed that siRNA targeting PLK1 mRNA had effectively knocked PLK1 mRNA down in SW480 cell line. And a blended siRNAs held the best knockdown effect. The cell was blocked on the mitosis and growth...
  31. doi MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility
    Liang Zhu
    Cancer Institute Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Zhejiang Province, China, The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, Zhejiang, China
    Med Oncol 29:1037-43. 2012
    ..The overexpression of miR-9 could also down-regulate α-catenin expression. These data suggest that miR-9 may potentially participate in the metastatic process of CRC though facilitating cell motility...
  32. pmc Doxorubicin-mediated radiosensitivity in multicellular spheroids from a lung cancer cell line is enhanced by composite micelle encapsulation
    Wen Hong Xu
    Department of Radiation Oncology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
    Int J Nanomedicine 7:2661-71. 2012
    ..The purpose of this study is to evaluate the efficacy of composite doxorubicinloaded micelles for enhancing doxorubicin radiosensitivity in multicellular spheroids from a non-small cell lung cancer cell line...
  33. pmc Discovering differential protein expression caused by CagA-induced ERK pathway activation in AGS cells using the SELDI-ProteinChip platform
    Zhen Ge
    Cancer Institute of Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang, China
    World J Gastroenterol 14:554-62. 2008
    ..To identify the protein expression differences related to the CagA-induced ERK pathway activation in AGS cells...
  34. ncbi [Application of serum protein markers to distinguish familial adenomatous polyposis (FAP) and sporadic colorectal adenomas]
    Shan Rong Cai
    The 2nd Affiliated Hospital, Medical School, Zhejiang University, Hangzhou 310009, China
    Zhonghua Zhong Liu Za Zhi 31:192-5. 2009
    ..To screen out specifically-expressed serum protein markers in familial adenomatous polyposis (FAP) and to establish a serum protein fingerprint diagnostic model for distinguishing FAP from sporadic colorectal adenomas...
  35. ncbi Clinical significance of vascular endothelial growth factor expression and neovascularization in colorectal carcinoma
    Shu Zheng
    Cancer Institute, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 9:1227-30. 2003
    ..To clarify the association of vascular endothelial growth factor (VEGF) and microvascular density (MVD) expression with the angiogenesis and prognosis of colorectal cancer...
  36. ncbi Genetic characterization of Chinese hereditary non-polyposis colorectal cancer by DHPLC and multiplex PCR
    Ying Yuan
    Cancer Research Institute, 2nd Hospital, Zhejiang University School of Medicine, 88 Jie Fang Road, Hangzhou, 310009 PR China
    Jpn J Clin Oncol 34:660-6. 2004
    ..The aim of the present study was to identify the point mutations and large genomic deletions of hMLH1 and hMSH2 genes in 14 Chinese HNPCC families...
  37. pmc Evaluation of ST13 gene expression in colorectal cancer patients
    Qing Hua Dong
    Cancer Institute, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 6:1170-5. 2005
    ..05). But there were no significant differences in the expression of ST13 as compared with different Dukes' stage, tumor differentiation grade, invasion depth, lymph node metastasis and disease-specific survival...
  38. ncbi [Induction of HSF1 expression and sporadic colorectal cancer]
    Yong Ming Fang
    The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 33:390-4. 2004
    ..To explore the activation of the signal transduction pathways related with the carcinogenesis of sporadic colon cancers...
  39. ncbi Special fasciculiform cataract caused by a mutation in the gammaD-crystallin gene
    Xingchao Shentu
    Eye Center, Affiliated Second Hospital, College of Medicine, Zhejiang University, Hangzhou, China
    Mol Vis 10:233-9. 2004
    ..To identify ultrastructure changes and genetic defects associated with a special fasciculiform autosomal dominant congenital cataract (ADCC) affecting a large Chinese family...
  40. pmc Expression of ST13 in colorectal cancer and adjacent normal tissues
    Lin Bo Wang
    Department of Surgical Oncology, Sir Run Run Shaw Hospital, Medical College, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
    World J Gastroenterol 11:336-9. 2005
    ..To investigate the in situ expression of suppression of tumorigenecity 13 (ST13) mRNA in both colorectal cancer and adjacent normal tissues...
  41. ncbi [Ultrastructure and crystallin mutant molecular modeling of hereditary coralliform cataract]
    Wei Zhen Xu
    The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:243-7. 2005
    ..To observe the correlation of gammaD-crystallin P23T mutant with lens ultrastructure of the hereditary coralliform cataract...
  42. pmc Preoperatively molecular staging with CM10 ProteinChip and SELDI-TOF-MS for colorectal cancer patients
    Wen Hong Xu
    Cancer Institute, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 7:235-40. 2006
    ....
  43. doi Inhibition of apoptosis by downregulation of hBex1, a novel mechanism, contributes to the chemoresistance of Bcr/Abl+ leukemic cells
    Kefeng Ding
    Cancer Institute, Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang Province, Hangzhou, PR China
    Carcinogenesis 30:35-42. 2009
    ..These data provide evidence that expression of hBex1 in leukemic cells is a novel mechanism by which chemoresistance is achieved and suggests that hBex1 is a potential molecular target for the development of novel leukemia treatments...
  44. doi Detection of renal allograft dysfunction with characteristic protein fingerprint by serum proteomic analysis
    Minmin Wang
    The Kidney Disease Center, the First Affiliated Hospital of Medical College, Zhejiang University, 79 Qingchun Road, Hangzhou, China
    Int Urol Nephrol 43:1009-17. 2011
    ..Specific markers were detected in each group. Identification of these proteins may prove useful as diagnostic markers for allograft dysfunction and better to elucidate the mechanism of acute rejection...
  45. pmc Performance value of high risk factors in colorectal cancer screening in China
    Wen Meng
    Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 15:6111-6. 2009
    ..To analyze the performance value of high risk factors in population-based colorectal cancer (CRC) screening in China...
  46. pmc Knockdown of OLA1, a regulator of oxidative stress response, inhibits motility and invasion of breast cancer cells
    Jia Wei Zhang
    Cancer Institute National Ministry of Education Key Laboratory of Cancer Prevention and Intervention, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 10:796-804. 2009
    ..These results suggest that knockdown of OLA1 inhibits breast cancer cell migration and invasion through a mechanism that involves the modulation of intracellular ROS levels...
  47. ncbi [Alcohol drinking and colorectal cancer: a population-based prospective cohort study]
    Kun Chen
    Department of Epidemiology, College of Medicine, Zhejiang University, Hangzhou 310031, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 33:411-5. 2004
    ..To understand the incidence of colorectal cancer in population drinking or not and to validate the relationship between drinking and colorectal cancer...
  48. ncbi [Effect of microRNA143 expression on cell proliferation in colonic carcinoma]
    Hong Liu
    Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
    Zhonghua Zhong Liu Za Zhi 30:498-501. 2008
    ..To investigate the effect of microRNA143 on cell proliferation and K-ras expression in colorectal carcinoma...
  49. doi The dominant negative mutant Artemis enhances tumor cell radiosensitivity
    Hai Liu
    Cancer Institute, Zhejiang University School of Medicine, The Second Affiliated Hospital, Hangzhou, China
    Radiother Oncol 101:66-72. 2011
    ..Intervention with DNA double-strand break repair is an effective way to modulate tumor cell radiosensitivity. This study focused on the mutant Artemis fragment-enhanced radiosensitivity of human cervical cancer cells...
  50. doi Predictive power of quantitative and qualitative fecal immunochemical tests for hemoglobin in population screening for colorectal neoplasm
    Yanqin Huang
    aKey Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine bJiashan Institute of Cancer Prevention and Treatment, Zhejiang Province, China
    Eur J Cancer Prev 23:27-34. 2014
    ..Quantitative FIT is superior to qualitative FIT in predicting advanced colorectal neoplasm during colorectal cancer screening. Further studies are needed to elucidate the causes of the predictive superiority. ..
  51. ncbi Effect of SNC19/ST14 gene overexpression on invasion of colorectal cancer cells
    Ke Feng Ding
    Surgery of Oncology, The Second Affiliated Hospital, School of Medicine, Zhejinag University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 11:5651-4. 2005
    ..To study the effect of SNC19/ST14 gene overexpression on invasion in vitro of colorectal cancer cells...
  52. ncbi Identification of the biomarkers for the prediction of efficacy in first-line chemotherapy of metastatic colorectal cancer patients using SELDI-TOF-MS and artificial neural networks
    Ying Yuan
    Department of Medical Oncology, China National Ministry of Education, China
    Hepatogastroenterology 59:2461-5. 2012
    ..There are no clinically useful markers that could predict the response to these regimens respectively. We aimed at identifying serum protein patterns which could predict the efficacy of chemotherapy...
  53. pmc MicroRNAs up-regulated by CagA of Helicobacter pylori induce intestinal metaplasia of gastric epithelial cells
    Yongliang Zhu
    Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
    PLoS ONE 7:e35147. 2012
    ..These results indicate that miRNA-584 and miRNA-1290 interfere with cell differentiation and remodel the tissues. Thus, the miRNA pathway is a new pathogenic mechanism of CagA...
  54. ncbi Silymarin causes caspases activation and apoptosis in K562 leukemia cells through inactivation of Akt pathway
    Xian Zhong
    Cancer Institute, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
    Toxicology 227:211-6. 2006
    ..These findings suggest that silymarin could serve as a candidate for anti-leukemia drug...
  55. doi ChIP-seq and functional analysis of the SOX2 gene in colorectal cancers
    Xuefeng Fang
    Cancer Institute Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People s Republic of China
    OMICS 14:369-84. 2010
    ....
  56. ncbi Cytidine deaminase APOBEC3B interacts with heterogeneous nuclear ribonucleoprotein K and suppresses hepatitis B virus expression
    Wei Zhang
    Second Affiliated Hospital, Cancer Institute, School of Medicine, Zhejiang University, Hangzhou 310009, China
    Cell Microbiol 10:112-21. 2008
    ..In addition, A3B protein may be a broad antiviral host factor. Thus, regulated A3B expression may contribute to non-cytolytic HBV clearance in vivo...
  57. pmc Comparative features of colorectal and gastric cancers with microsatellite instability in Chinese patients
    Yan Qin Huang
    Key Laboratory of Cancer Prevention and Intervention of Ministry of Education, Key Laboratory of Molecular Biology in Medical Science of Zhejiang Province, Cancer Institute, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 11:647-53. 2010
    ..The purpose of this study was to determine the unique and universal features of microsatellite instability-high (MSI-H) colorectal cancer (CRC) and MSI-H gastric cancer (GC) in the Chinese population...
  58. ncbi Apoptosis induction with polo-like kinase-1 antisense phosphorothioate oligodeoxynucleotide of colon cancer cell line SW480
    Yu Fan
    Cancer Institute, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 11:4596-9. 2005
    ..To investigate the effects of polo-like kinase-1 (PLK1) antisense phosphorothioate oligodeoxynucleotide (ASODN) on apoptosis and cell cycle of human colon cancer cell line SW480...
  59. pmc Overexpression of Shp2 tyrosine phosphatase is implicated in leukemogenesis in adult human leukemia
    Rongzhen Xu
    Department of Hematology, Second Affiliated Hospital, School of Medicine, Cancer Institute, Zhejiang University, Zhejiang Academy of Medical Sciences, Hangzhou, Zhejiang 310009, China
    Blood 106:3142-9. 2005
    ..Based on these results, we propose that aberrantly increased expression of Shp2 may contribute, collaboratively with other factors, to leukemogenesis...
  60. pmc Targeted re-sequencing identified rs3106189 at the 5' UTR of TAPBP and rs1052918 at the 3' UTR of TCF3 to be associated with the overall survival of colorectal cancer patients
    Jiaofang Shao
    Cancer Institute Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
    PLoS ONE 8:e70307. 2013
    ....
  61. pmc The crosstalk: Tumor-infiltrating lymphocytes rich in regulatory T cells suppressed cancer-associated fibroblasts
    Zhixuan Fu
    Key Laboratory of Cancer Prevention and Intervention, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, P R China
    Acta Oncol 52:1760-70. 2013
    ..However, studies related to the crosstalk between CAFs and TILs in tumor microenvironment (TME) are still lacking. In this study, we mainly investigated the interactions between CAFs and TILs...
  62. doi CaMKII γ, a critical regulator of CML stem/progenitor cells, is a target of the natural product berbamine
    Ying Gu
    Department of Hematology, Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Hangzhou, China
    Blood 120:4829-39. 2012
    ....
  63. ncbi [Classification and diagnostic prediction of colorectal cancer using protein profiling of serum and bioinformatics]
    Yi Ding Chen
    Department of Oncology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 38:470-7. 2009
    ..To develop a bioinformatic tool and to use it to identify proteomic patterns in serum, distinguishing colorectal cancer from colorectal adenoma and healthy individuals...
  64. ncbi [Association of drinking water source and colorectal cancer incidence: a prospect cohort study]
    Kun Chen
    Department of Epidemiology, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310031, PR China
    Ai Zheng 23:550-4. 2004
    ..There is little prospect cohort study with person-years directly on the relative risks of different sources of drinking water for CRC...
  65. pmc Induced pluripotent stem cell-related genes influence biological behavior and 5-fluorouracil sensitivity of colorectal cancer cells
    Zhong Shi
    Cancer Institute, Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Zhejiang Province, China
    J Zhejiang Univ Sci B 13:11-9. 2012
    ....
  66. pmc Characterization of CagA variable region of Helicobacter pylori isolates from Chinese patients
    Yong Liang Zhu
    Department of Gastroenterology, Second Hospital of Zhejiang University College of Medicine, Hangzhou, China
    World J Gastroenterol 11:880-4. 2005
    ..To characterize the CagA variable region of Helicobacter pylori isolates from Chinese patients...
  67. doi Identification and characterization of a small inhibitory peptide that can target DNA-PKcs autophosphorylation and increase tumor radiosensitivity
    Xiaonan Sun
    Department of Radiation Oncology, Sir Run Run Shaw Hospital, Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, Hangzhou, China
    Int J Radiat Oncol Biol Phys 84:1212-9. 2012
    ..Here, we aimed to develop small inhibitory peptides that could specifically target DNA-PKcs autophosphorylation, a critical step for the enzymatic activation of the kinase in response to IR...
  68. pmc Epidermal growth factor receptor-regulated miR-125a-5p--a metastatic inhibitor of lung cancer
    Guofu Wang
    Department of Respiratory Disease, Zhejiang Hospital, Hangzhou, China
    FEBS J 276:5571-8. 2009
    ..Taken together, our results provide compelling evidence that miR-125a-5p, an epidermal growth factor-signaling-regulated miRNA, may function as a metastatic suppressor...
  69. ncbi Inducible nitric oxide synthase expression is related to angiogenesis, bcl-2 and cell proliferation in hepatocellular carcinoma
    Jia Ping Peng
    Cancer Institute, College of Medicine, Zhejiang University, Hangzhou, 310009, China
    J Zhejiang Univ Sci 4:221-7. 2003
    ..The present findings suggested that iNOS expression was significantly associated with angiogenesis, bcl-2 and cell proliferation of HCC...
  70. doi Potent antitumor activity of double-regulated oncolytic adenovirus-mediated ST13 for colorectal cancer
    De Bin Yu
    Xinyuan Institute of Medicine and Biotechnology, Zhejiang Sci Tech University, Hangzhou, China
    Cancer Sci 100:678-83. 2009
    ..To further identify the antitumor effects of SG500-ST13 on HCT116 xenografts in Balb/c nude mice, the induction of cell death was assessed by hematoxylin-eosin staining. Immunohistochemical study was also carried out...
  71. ncbi Artificial neural networks analysis of surface-enhanced laser desorption/ionization mass spectra of serum protein pattern distinguishes colorectal cancer from healthy population
    Yi Ding Chen
    Department of Oncology, Second Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, People s Republic of China
    Clin Cancer Res 10:8380-5. 2004
    ..We developed and evaluated a proteomic approach for the simultaneous detection and analysis of multiple proteins for distinguishing individuals with colorectal cancer from healthy individuals...
  72. doi MicroRNA-183 regulates Ezrin expression in lung cancer cells
    Guofu Wang
    The 2nd Affiliated Hospital, School of Medicine, College of Life Sciences, Zhejiang University, Hangzhou, China
    FEBS Lett 582:3663-8. 2008
    ..We also found that miR-183 could regulate the expression of other genes involved in migration and invasion. Taken together, our findings demonstrated a new role and regulatory mechanism of miR-183 in controlling cancer metastasis...
  73. pmc SPARCL1, Shp2, MSH2, E-cadherin, p53, ADCY-2 and MAPK are prognosis-related in colorectal cancer
    Shu jing Yu
    Department of Radiation Oncology, The Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 17:2028-36. 2011
    ..To investigate the expression of markers that are correlated with the prognosis of colorectal cancer (CRC) patients...
  74. ncbi [SNC19/ST14 gene transfection and expression influence the biological behavior of colorectal cancer cells]
    Li Feng Sun
    Cancer Institute, The Second Affiliated Hospital, Medical College of Zhejiang University, Hangzhou 310009, China
    Zhonghua Yi Xue Za Zhi 84:843-8. 2004
    ..To study the effect of SNC19/ST14 gene transfection and expression into colorectal cancer cells on biological behavior...
  75. ncbi Autosomal dominant coralliform cataract related to a missense mutation of the gammaD-crystallin gene
    Wei Zhen Xu
    Cancer Institute, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
    Chin Med J (Engl) 117:727-32. 2004
    ..About 25% of all cases are due to genetic defects. We identified autosomal dominant congenital coralliform cataracts-related genetic defect in a four-generation Chinese family...
  76. doi Impact of a laparoscopic resection on the quality of life in rectal cancer patients: results of 135 patients
    Jun Li
    Department of Surgical Oncology, Second Affiliated Hospital, and The Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Zhejiang University College of Medicine, No 88 Jiefang Road, Hangzhou, 310009 Zhejiang Province, PR China
    Surg Today 40:917-22. 2010
    ..To investigate the impact of a laparoscopic resection on the quality of life in rectal cancer patients...
  77. pmc Clinical significance of K-ras and BRAF mutations in Chinese colorectal cancer patients
    Hong Shen
    Department of Oncology, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 17:809-16. 2011
    ..To identify and assess mutations in the K-ras and BRAF genes in a cohort of Chinese patients with colorectal cancer (CRC) for their association with various clinicopathological parameters and prognosis...
  78. ncbi Study on interleukin-18 gene transfer into human breast cancer cells to prevent tumorigenicity
    Ming Yong Han
    Cancer Institute, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci 5:472-6. 2004
    ..The Bcap37 cells transduced with IL-18 gene may be used as breast cancer vaccine...
  79. pmc Proteomic analysis of primary colon cancer-associated fibroblasts using the SELDI-ProteinChip platform
    Zhan Huai Wang
    Cancer Institute, The Second Affiliated Hospital School of Medicine, Zhejiang University, Hangzhou, China
    J Zhejiang Univ Sci B 13:159-67. 2012
    ..However, the unique protein expression of CAFs has not been fully elucidated. This study aims to investigate the characterizations of colon CAFs by comparing the differential protein expression between CAFs and normal fibroblasts...
  80. ncbi [Mutational studies of adenomatous polyposis coli gene in carcinomas from patients with hereditary non-polyposis colorectal cancers]
    Jian Huang
    Department of Oncology, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310009 PR China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20:196-9. 2003
    ..To analyze the mutational features of adenomatous polyposis coli (APC) gene and to explore the effect of mismatch repair (MMR) deficiency on its mutations in hereditary non-polyposis colorectal cancers (HNPCC)...
  81. ncbi [Diagnostic application of serum protein pattern and artificial neural network software in breast cancer]
    Yue Hu
    Cancer Institute, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310 009, P R China
    Ai Zheng 24:67-71. 2005
    ....
  82. pmc Quantitative real-time RT-PCR detection for CEA, CK20 and CK19 mRNA in peripheral blood of colorectal cancer patients
    Dong Xu
    Cancer Institute, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 7:445-51. 2006
    ..Our study indicates that quantitative real-time RT-PCR detection for CEA, CK20 and CK19 mRNA in peripheral blood is a valuable tool for monitoring early stage dissemination of CRC cells in blood circulation...
  83. ncbi [Effect of Kanglaite injection oncyclooxygenase activity in lung carcinoma A549 cell]
    Qing Hua Dong
    The 2nd Affiliated Hospital of Zhejiang University, Cancer Institute, Zhejiang University, Hangzhou 310016, China
    Zhongguo Zhong Yao Za Zhi 30:1621-3, 1633. 2005
    ..To study the effect of Kanglaite injection on cyclooxygenase activity in lung carcinoma A549 cells...
  84. ncbi Clinical features of familial adenomas polyps in Chinese and establishment of its immortal lymphocyte cell lines
    Shan Rong Cai
    Cancer Institute, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 13:2858-61. 2007
    ..To reserve the rare Chinese familial adenomas polyp (FAP) family resource and to investigate the clinical features of FAP in Chinese for its diagnosis...
  85. ncbi Association of human APOBEC3 cytidine deaminases with the generation of hepatitis virus B x antigen mutants and hepatocellular carcinoma
    Rongzhen Xu
    Second Affiliated Hospital, Cancer Institute, School of Medicine, Zhejiang University, Hangzhou, China
    Hepatology 46:1810-20. 2007
    ..Deregulated expression of A3B in liver tissues may also have the potential to promote genetic instability and tumorigenesis...
  86. ncbi [Study on post-translational processing and active forms of the novel metastasis-associated protein SNC19]
    Ying Shi
    The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:38-42. 2005
    ..To investigate the relationship between SNC19 protein and cancer metastasis...
  87. ncbi CYP1A1, GSTs and mEH polymorphisms and susceptibility to esophageal carcinoma: study of population from a high- incidence area in north China
    Li Dong Wang
    Cancer Institute, Zhejiang University, Hangzhou, Zheijiang Province, China
    World J Gastroenterol 9:1394-7. 2003
    ..To characterize cytochrome P4501A1 (CYP1A1), glutathione S-transferases (GSTs) and microsomal epoxide hydrolase (mEH) polymorphisms in Chinese esophageal cancer patients...
  88. doi Influences of laparoscopic resection on expressions of metastasis genes in colorectal cancer: report of microarray analysis and literature review
    Jun Li
    Department of Social Oncology, Zhejiang University College of Medicine, Hangzhou, China
    Hepatogastroenterology 58:1975-82. 2011
    ..To comprehensively understand the influence of laparoscopic resection on expressions of metastasis related genes in colorectal cancer by microarray...
  89. ncbi [Combined detection of CEA mRNA and CK 19 mRNA in peripheral blood cells of patients with lung cancer]
    Xu fen Li
    Department of Oncology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China
    Zhonghua Zhong Liu Za Zhi 26:382-4. 2004
    ..To investigate the expression of CEA mRNA and CK(19) mRNA in peripheral blood cells of patients with lung cancer and evaluate its clinical significance...
  90. ncbi Effective induction of therapeutic antitumor immunity by dendritic cells coexpressing interleukin-18 and tumor antigen
    Dajing Xia
    Institute of Immunology, Zhejiang University, 310031, Hangzhou, P R China
    J Mol Med (Berl) 81:585-96. 2003
    ..These results indicate that immunization with DC vaccine coexpressing Th1 cytokine IL-18 and tumor antigen gene may be an effective strategy for a successful therapeutic vaccination...
  91. pmc Influence of CO2 pneumoperitoneum on intracellular pH and signal transduction in cancer cells
    Li Ping Cao
    Department of Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    J Zhejiang Univ Sci B 6:650-5. 2005
    ..The authors studied the influence of CO(2) pneumoperitoneum on intracellular pH and signal transduction arising from cancer cell multiplication in laparoscopic tumor operation...
  92. ncbi Ricin A chain reaches the endoplasmic reticulum after endocytosis
    Qiong Liu
    Department of Biochemistry and Molecular Biology, Zhejiang University Medical School, Hangzhou 310006, PR China
    Biochem Biophys Res Commun 343:857-63. 2006
    ..This study provided important evidence by a visualized way to prove that RTA does reach the endoplasmic reticulum...
  93. ncbi [Expression and recombination mechanism of SNC73 (IgHalpha1) in human epithelial cancer cell line]
    Li Yi Geng
    Cancer Institute, Zhejiang University, Hangzhou 310009, China
    Zhonghua Yi Xue Za Zhi 83:1493-6. 2003
    ..To study if the gene SNC73 (IgHalpha1) is expressed in human epithelial cancer cell line and to interpret the recombination mechanism...
  94. ncbi [The microencapsulated genetic engineering cells: a new platform on treatment of cancer instead of genetic engineering drugs]
    Yuelong Pan
    Cancer Institute, Zhejiang University, Hangzhou 310009
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 20:345-7. 2003
    ..This article reviews and summarizes the advantages, possible problems and solution and the feasibility of using microencapsulated genetic engineering cells in the treatment of cancer...
  95. doi Potent antitumor efficacy of ST13 for colorectal cancer mediated by oncolytic adenovirus via mitochondrial apoptotic cell death
    Min Yang
    Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Hum Gene Ther 19:343-53. 2008
    ..In summary, overexpressed ST13 as mediated by oncolytic adenovirus could exert potent antitumor activity via the intrinsic apoptotic pathway and has the potential to become a novel therapeutic for colorectal cancer gene therapy...
  96. ncbi Development of antibody-based assays for omega-conotoxin MVIIA
    Feng Wang
    Department of Biochemistry, Zhejiang University Medical School, Hangzhou 310006, China
    J Biochem Biophys Methods 67:49-56. 2006
    ..Thus, the assays based on this antibody are useful for the conotoxin analysis...
  97. doi Isolation and characterization of radiation-resistant lung cancer D6-R cell line
    Qi Chun Wei
    Ministry of Education Key Laboratory of Cancer Prevention and Intervention, Zhejiang University, Hangzhou 310009, Zhejiang, China
    Biomed Environ Sci 21:339-44. 2008
    ..To isolate an isogenic radioresistant cancer cell line after fractioned X-ray radiation and characterize the resistant cells...
  98. ncbi [Subcutaneous transplantation of microencapsulated Chinese hamster ovary (CHO) cells/pcDNA 3.1/mIL-12 and subcutaneous transplantation of microencapsulated CHO/pcDNA3.1/mIL-12 combined with 5-fluoro-uracil in treatment of tumor-burdened mice]
    Yue Long Pan
    Cancer Institute, Zhejiang University, Hangzhou 310009, China
    Zhonghua Yi Xue Za Zhi 83:51-4. 2003
    ..1/mIL-12 and subcutaneous transplantation of microencapsulated CHO/pcDNA3.1/mIL-12 combined with 5-fluoro-uracilum (5-FU) in treatment of tumor-burdened mice...
  99. ncbi Expression of a novel immunoglobulin gene SNC73 in human cancer and non-cancerous tissues
    Jian Bin Hu
    Department of Radiation Oncology, Sir Run Run Shaw Hospital, Zhejiang University Medical College, Hangzhou, Zhejiang Province, China
    World J Gastroenterol 9:1054-7. 2003
    ..To investigate the expression of immunoglobulin gene SNC73 in malignant tumors and non-cancerous normal tissues...
  100. ncbi [protein toxins and their medical applications]
    Jin Biao Zhan
    Department of Biochemistry and Molecular Biology, College of Medicine, Zhejiang University, Hangzhou 310006, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:197-200. 2005