Bao Rong Zhang

Summary

Affiliation: Zhejiang University
Country: China

Publications

  1. doi request reprint Genetic variants in the RAB7L1 and SLC41A1 genes of the PARK16 locus in Chinese Parkinson's disease patients
    Yaping Yan
    Department of Neurology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
    Int J Neurosci 121:632-6. 2011
  2. doi request reprint Mutation analysis of parkin and PINK1 genes in early-onset Parkinson's disease in China
    Bao Rong Zhang
    Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, No 88 Jiefang Road, Hangzhou, Zhejiang 310009, China
    Neurosci Lett 477:19-22. 2010
  3. doi request reprint CCG polymorphisms in the huntingtin gene have no effect on the pathogenesis of patients with Huntington's disease in mainland Chinese families
    Bao Rong Zhang
    Department of Neurology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    J Neurol Sci 312:92-6. 2012
  4. ncbi request reprint Novel human pathological mutations. Gene symbol: FRMD7. Disease: congenital motor nystagmus
    Baorong Zhang
    Hum Genet 122:414. 2007
  5. ncbi request reprint Novel human pathological mutations. Gene symbol: FRMD7. Disease: congenital motor nystagmus
    Baorong Zhang
    Hum Genet 122:414. 2007
  6. ncbi request reprint Confirmation and refinement of a genetic locus of congenital motor nystagmus in Xq26.3-q27.1 in a Chinese family
    Baorong Zhang
    Department of Neurology of Second Hospital, Affiliated Zhejiang University, 310009 Hangzhou, China
    Hum Genet 116:128-31. 2005
  7. ncbi request reprint Novel mutations of the FRMD7 gene in X-linked congenital motor nystagmus
    Baorong Zhang
    Department of Neurology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
    Mol Vis 13:1674-9. 2007
  8. ncbi request reprint [IT15 gene analysis in two pedigrees of Huntington's disease]
    Bao Rong Zhang
    Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    Yi Chuan 28:1345-9. 2006
  9. ncbi request reprint [Mutation analysis of keratin 9 gene in a pedigree with epidermolytic palmoplantar keratoderma]
    Bao Rong Zhang
    Department of Neurology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310009 P R China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 21:570-3. 2004
  10. ncbi request reprint [Mapping of a pedigree with congenital nystagmus]
    Zhi Rong Liu
    Department of Neurology, the Second Affiliated Hospital of Medical School, Zhejiang University, Hangzhou 310 009, China
    Yi Chuan 26:437-40. 2004

Collaborators

Detail Information

Publications24

  1. doi request reprint Genetic variants in the RAB7L1 and SLC41A1 genes of the PARK16 locus in Chinese Parkinson's disease patients
    Yaping Yan
    Department of Neurology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
    Int J Neurosci 121:632-6. 2011
    ..Further analysis is required to determine the role of genes within the PARK16 locus in development of PD...
  2. doi request reprint Mutation analysis of parkin and PINK1 genes in early-onset Parkinson's disease in China
    Bao Rong Zhang
    Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, No 88 Jiefang Road, Hangzhou, Zhejiang 310009, China
    Neurosci Lett 477:19-22. 2010
    ..05). We concluded that mutations in parkin gene are common in Chinese EOPD patients, and mainly are exon rearrangements, while mutation in PINK1 might be not common in Chinese EOPD patients...
  3. doi request reprint CCG polymorphisms in the huntingtin gene have no effect on the pathogenesis of patients with Huntington's disease in mainland Chinese families
    Bao Rong Zhang
    Department of Neurology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    J Neurol Sci 312:92-6. 2012
    ..Given these findings, it was quite reasonable to suppose that the CCG polymorphism may not influence the pathogenesis of patients with HD in mainland China...
  4. ncbi request reprint Novel human pathological mutations. Gene symbol: FRMD7. Disease: congenital motor nystagmus
    Baorong Zhang
    Hum Genet 122:414. 2007
  5. ncbi request reprint Novel human pathological mutations. Gene symbol: FRMD7. Disease: congenital motor nystagmus
    Baorong Zhang
    Hum Genet 122:414. 2007
  6. ncbi request reprint Confirmation and refinement of a genetic locus of congenital motor nystagmus in Xq26.3-q27.1 in a Chinese family
    Baorong Zhang
    Department of Neurology of Second Hospital, Affiliated Zhejiang University, 310009 Hangzhou, China
    Hum Genet 116:128-31. 2005
    ..4-cM region at chromosome Xq26.3-q27.1. The SLC9A6 and FGF13 genes in this region, were selected and screened for mutation in this family, but no mutation was detected...
  7. ncbi request reprint Novel mutations of the FRMD7 gene in X-linked congenital motor nystagmus
    Baorong Zhang
    Department of Neurology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
    Mol Vis 13:1674-9. 2007
    ..Recently, the FRMD7 gene mutation has been identified as the genetic cause of CMN. The purpose of this study was to identify mutations of the FRMD7 gene in Chinese patients with CMN...
  8. ncbi request reprint [IT15 gene analysis in two pedigrees of Huntington's disease]
    Bao Rong Zhang
    Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    Yi Chuan 28:1345-9. 2006
    ..In conclusion, the clinical symptoms are partly determined by (CAG)n repeats in the IT15 gene. The age of onset was correlated with (CAG)n repeats over 50, and the phenomenon called "anticipation" was found to have played a role...
  9. ncbi request reprint [Mutation analysis of keratin 9 gene in a pedigree with epidermolytic palmoplantar keratoderma]
    Bao Rong Zhang
    Department of Neurology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310009 P R China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 21:570-3. 2004
    ..To identify mutations of keratin 9 (KRT9) gene in a big Chinese family with epidermolytic palmoplantar keratoderma(EPPK) combined with knuckle-pad-like lesions and nail lesions...
  10. ncbi request reprint [Mapping of a pedigree with congenital nystagmus]
    Zhi Rong Liu
    Department of Neurology, the Second Affiliated Hospital of Medical School, Zhejiang University, Hangzhou 310 009, China
    Yi Chuan 26:437-40. 2004
    ..The related gene of this pedigree was located on the long arm of X chromosome. We demonstrate that Xq26-Xq28 is a common locus for CMN. It bring us closer to the identification of a gene responsible for X-linked CMN...
  11. ncbi request reprint [Pathological features and gene mutation analysis in two pedigrees of diffuse palmoplantar keratoderma]
    Xin Zhen Yin
    Department of Neurology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    Yi Chuan 29:301-5. 2007
    ..N160S and L167S of KRT9 are disease-causing mutations in these two Chinese pedigrees with epidermolytic palmoplanter keratoderma (EPPK)...
  12. doi request reprint An association between the PARK16 locus and Parkinson's disease in a cohort from eastern China
    Ya Ping Yan
    Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, No 88 Jiefang Road, Hangzhou, Zhejiang, PR China
    Parkinsonism Relat Disord 17:737-9. 2011
    ..Further analyses from more diverse ethnic origins are required to confirm the significance of rs16856139 and rs11240572...
  13. ncbi request reprint [The clinical features and gene mutation analysis in a pedigree of spinocerebellar ataxia type 7]
    Xin Zhen Yin
    Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
    Yi Chuan 29:688-92. 2007
    ..Therefore, this is a pedigree of SCA7. Analysis of the CAG trinucleotide repeat expansion at the SCA7 locus can provide valuable insights into SCA7...
  14. ncbi request reprint [Clinical, pathological and genetic studies in a Chinese Charcot-Marie-Tooth disease type 2 family]
    Wei Luo
    Department of Neurology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:529-33. 2005
    ..To report a Chinese Charcot-Marie-Tooth disease type 2 (CMT2) family...
  15. doi request reprint Report of two Chinese families and a review of Mainland Chinese CADASIL patients
    Xin Zhen Yin
    Department of Neurology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
    J Neurol Sci 279:88-92. 2009
    ..This study supports that the clinical features of Mainland Chinese CADASIL patients are similar to those seen in other regions and that exon 3 and exon 4 of the NOTCH3 gene are the mutation hotspots in Mainland Chinese CADASIL patients...
  16. doi request reprint Study of methylation levels of parkin gene promoter in Parkinson's disease patients
    Miao Cai
    Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
    Int J Neurosci 121:497-502. 2011
    ..05). These results suggest that the methylation mechanism is unlikely to play a role in the pathogenesis and development of PD...
  17. ncbi request reprint [Clinical and genetic analysis of a pedigree of Kennedy disease]
    Zhi Yuan Ou-Yang
    Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 40:555-8. 2011
    ..To review the clinical and genetic features of a pedigree of Kennedy disease in China...
  18. ncbi request reprint [The studies on clinical manifestation, histopathology and imaging of MELAS]
    Bao Rong Zhang
    The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:85-8. 2005
  19. pmc Validity and reliability testing of the Chinese (mainland) version of the 39-item Parkinson's Disease Questionnaire (PDQ-39)
    Wei Luo
    Department of Neurology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    J Zhejiang Univ Sci B 11:531-8. 2010
    ..Although our observations indicate that some problematic subscales of this version of the PDQ-39 could be improved upon, this study suggests acceptable reliability and validity of the Chinese (mainland) version of the PDQ-39...
  20. doi request reprint Soluble N-terminal fragment of mutant Huntingtin protein impairs mitochondrial axonal transport in cultured hippocampal neurons
    Jun Tian
    Department of Neurology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310009, China
    Neurosci Bull 30:74-80. 2014
    ..We predict that dysfunction of mitochondrial axonal transport is an early-stage event in the progression of HD, even before mHtt aggregates are formed. ..
  21. pmc An insulinoma with clinical and electroencephalographic features resembling complex partial seizures
    Shuang Wang
    Department of Neurology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 9:496-9. 2008
    ..This report highlights the need for careful reassessment of all seizures refractory to medication, even for the patients associated with epileptiform discharges on EEG...
  22. doi request reprint [Construction of wild-type and mutant SPAST vectors for the study of molecular mechanism of hereditary spastic paraplegia]
    Ya Ping Yan
    Department of Neurology, Zhejiang University, Hangzhou, Zhejiang, People s Republic of China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 30:9-12. 2013
    ..To construct wild-type and mutant pEGFP SPAST vectors and to explore the molecular mechanism of hereditary spastic paraplegia...
  23. pmc Lance-Adams syndrome: a report of two cases
    Yan Xing Zhang
    Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 8:715-20. 2007
    ..We also review the literature on the neuroimaging, pathogenesis, and treatment of LAS...
  24. pmc A novel Twinkle (PEO1) gene mutation in a Chinese family with adPEO
    Zhirong Liu
    Department of Neurology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
    Mol Vis 14:1995-2001. 2008
    ..Thus far, disease loci have been identified on four different nuclear genes. The purpose of this study is to identify the gene responsible for causing adPEO in a Chinese family...