Duo Li

Summary

Affiliation: Zhejiang University
Country: China

Publications

  1. doi request reprint Chemistry behind Vegetarianism
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    J Agric Food Chem 59:777-84. 2011
  2. pmc Effect of n-3 polyunsaturated fatty acid on gene expression of the critical enzymes involved in homocysteine metabolism
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, 310029 China
    Nutr J 11:6. 2012
  3. doi request reprint Ratio of n-3/n-6 PUFAs and risk of breast cancer: a meta-analysis of 274135 adult females from 11 independent prospective studies
    Bo Yang
    Department of Food Science and Nutrition, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
    BMC Cancer 14:105. 2014
  4. pmc Association of homocysteine with type 2 diabetes: a meta-analysis implementing Mendelian randomization approach
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou 310029, China
    BMC Genomics 14:867. 2013
  5. ncbi request reprint Myricetin induces apoptosis in HepG2 cells through Akt/p70S6K/bad signaling and mitochondrial apoptotic pathway
    Xiao Hong Zhang
    Department of Food Science and Nutrition, School of Biosystems Engineering and Food Science, Zhejiang University, Yuhangtang Road 388, Hangzhou 310029, China
    Anticancer Agents Med Chem 13:1575-81. 2013
  6. doi request reprint Diacylglycerol-induced improvement of whole-body insulin sensitivity in type 2 diabetes mellitus: a long-term randomized, double-blind controlled study
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou, Zhejiang 310029, China
    Clin Nutr 27:203-11. 2008
  7. ncbi request reprint Seasonal variations of lipid content and composition in Perna viridis
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China, 310029
    Lipids 42:739-47. 2007
  8. ncbi request reprint Platelet phospholipid n-3 PUFA negatively associated with plasma homocysteine in middle-aged and geriatric hyperlipaemia patients
    D Li
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou, Zhejiang 310029, China
    Prostaglandins Leukot Essent Fatty Acids 76:293-7. 2007
  9. ncbi request reprint Alpha-linolenic acid content of commonly available nuts in Hangzhou
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Int J Vitam Nutr Res 76:18-21. 2006
  10. ncbi request reprint A significant inverse relationship between concentrations of plasma homocysteine and phospholipid docosahexaenoic acid in healthy male subjects
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China, 310029
    Lipids 41:85-9. 2006

Collaborators

Detail Information

Publications83

  1. doi request reprint Chemistry behind Vegetarianism
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    J Agric Food Chem 59:777-84. 2011
    ..This may be associated with an increased thrombotic and atherosclerotic risk. It is suggested that vegetarians, especially vegans, should increase their dietary n-3 PUFA and vitamin B₁₂ intakes...
  2. pmc Effect of n-3 polyunsaturated fatty acid on gene expression of the critical enzymes involved in homocysteine metabolism
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, 310029 China
    Nutr J 11:6. 2012
    ..Previous studies showed that plasma n-3 polyunsaturated fatty acid (PUFA) was negatively associated with plasma homocysteine (Hcy)...
  3. doi request reprint Ratio of n-3/n-6 PUFAs and risk of breast cancer: a meta-analysis of 274135 adult females from 11 independent prospective studies
    Bo Yang
    Department of Food Science and Nutrition, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
    BMC Cancer 14:105. 2014
    ..The purpose of this study is to ascertain the relationship between intake ratio of n-3/n-6 PUFAs and the risk of BC, and estimate the potential summarized dose-response trend...
  4. pmc Association of homocysteine with type 2 diabetes: a meta-analysis implementing Mendelian randomization approach
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou 310029, China
    BMC Genomics 14:867. 2013
    ..We tested the hypothesis that elevated homocysteine (Hcy) level is causally associated with increased risk of type 2 diabetes mellitus (T2DM)...
  5. ncbi request reprint Myricetin induces apoptosis in HepG2 cells through Akt/p70S6K/bad signaling and mitochondrial apoptotic pathway
    Xiao Hong Zhang
    Department of Food Science and Nutrition, School of Biosystems Engineering and Food Science, Zhejiang University, Yuhangtang Road 388, Hangzhou 310029, China
    Anticancer Agents Med Chem 13:1575-81. 2013
    ..Present results provide new information on the possible mechanisms for the anti-cancer activity of myricetin. ..
  6. doi request reprint Diacylglycerol-induced improvement of whole-body insulin sensitivity in type 2 diabetes mellitus: a long-term randomized, double-blind controlled study
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou, Zhejiang 310029, China
    Clin Nutr 27:203-11. 2008
    ..The aim of this study was to investigate the effect of diacylglycerol oil on risk factors of type 2 diabetes mellitus (DM) and cardiovascular disease in type 2 DM patients...
  7. ncbi request reprint Seasonal variations of lipid content and composition in Perna viridis
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China, 310029
    Lipids 42:739-47. 2007
    ....
  8. ncbi request reprint Platelet phospholipid n-3 PUFA negatively associated with plasma homocysteine in middle-aged and geriatric hyperlipaemia patients
    D Li
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou, Zhejiang 310029, China
    Prostaglandins Leukot Essent Fatty Acids 76:293-7. 2007
    ..The present results suggest that increased ratio of n-3/n-6 PUFA in platelet PL is associated with decreased thrombotic risks such as plasma Hcy in middle-aged and geriatric hyperlipaemia patients in Hangzhou...
  9. ncbi request reprint Alpha-linolenic acid content of commonly available nuts in Hangzhou
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Int J Vitam Nutr Res 76:18-21. 2006
    ..Cannabis sativa and walnut contained relatively high 18:3n-3, consumption of several these nuts each day can contribute to n-3 PUFA intake, especially for the vegetarian population...
  10. ncbi request reprint A significant inverse relationship between concentrations of plasma homocysteine and phospholipid docosahexaenoic acid in healthy male subjects
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China, 310029
    Lipids 41:85-9. 2006
    ..The mechanism that might explain the association between plasma 22:6n-3 and Hcy levels is not clear...
  11. ncbi request reprint Plasma coagulation factor VII activity and its correlates in healthy men
    D Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Eur J Clin Nutr 59:1423-8. 2005
    ..The aim of this study was to investigate the plasma coagulation factor VII activity and its correlates in healthy Australian men...
  12. ncbi request reprint Fish and its multiple human health effects in times of threat to sustainability and affordability: are there alternatives?
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou, Zhejiang, China 310029
    Asia Pac J Clin Nutr 18:553-63. 2009
    ..China's success in this area is a good model for other developing countries...
  13. ncbi request reprint Lean meat and heart health
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, Zhejiang, China
    Asia Pac J Clin Nutr 14:113-9. 2005
    ..In conclusion, lean red meat, trimmed of visible fat, which is consumed in a diet low in saturated fat does not increase cardiovascular risk factors (plasma cholesterol levels or thrombotic risk factors)...
  14. ncbi request reprint Cuisine: Hangzhou foods and their role in community health and nutrition
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou, 310029, China
    Asia Pac J Clin Nutr 13:141-6. 2004
    ..There is extensive use of plant based foods high in complex phytochemicals and trace elements. This combination leads to a balanced nutrition that contributes to the community health in Hangzhou...
  15. doi request reprint Interactions between genetic variants of folate metabolism genes and lifestyle affect plasma homocysteine concentrations in the Boston Puerto Rican population
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, People s Republic of China
    Public Health Nutr 14:1805-12. 2011
    ..To investigate genetic and lifestyle factors and their interactions on plasma homocysteine (Hcy) concentrations in the Boston Puerto Rican population...
  16. doi request reprint Expression of recombinant AccMRJP1 protein from royal jelly of Chinese honeybee in Pichia pastoris and its proliferation activity in an insect cell line
    Lirong Shen
    Department of Food Science and Nutrition, Zhejiang University 268 Kaixuan Road, Hangzhou, Zhejiang, China 310029
    J Agric Food Chem 58:9190-7. 2010
    ..The recombinant AccMRJP1 significantly stimulated Tn-5B-4 cell growth, similar to AmSPRJ and fetal bovine serum, and affected cell shape and adhesion to the substrate...
  17. pmc Consumption of Chinese tea-flavor liquor improves circulating insulin levels without affecting hepatic lipid metabolism-related gene expression in Sprague-Dawley rats
    Ju Sheng Zheng
    Department of Food Science and Nutrition, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
    ScientificWorldJournal 2013:842343. 2013
    ..To examine the effect of two Chinese liquors with quite different nonalcoholic components on insulin sensitivity, tissue polyunsaturated fatty acids (PUFA), and hepatic lipid metabolism in SD rats...
  18. pmc Genetic variants at PSMD3 interact with dietary fat and carbohydrate to modulate insulin resistance
    Ju Sheng Zheng
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    J Nutr 143:354-61. 2013
    ..Our study suggests that PSMD3 variants are associated with insulin resistance in populations of different ancestries and that these relationships may also be modified by dietary factors...
  19. doi request reprint Serum levels of polyunsaturated fatty acids are low in Chinese men with metabolic syndrome, whereas serum levels of saturated fatty acids, zinc, and magnesium are high
    Yinghua Yu
    Department of Food Science and Nutrition, Zhejiang University, Zhejiang Province 310058, China
    Nutr Res 32:71-7. 2012
    ..These changes may reflect improper dietary intake in subjects with MetS, and dietary modification could be useful to prevent MetS and as an adjunctive therapy...
  20. doi request reprint Increased plasma n-3 polyunsaturated fatty acid is associated with improved insulin sensitivity in type 2 diabetes in China
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, P R China
    Mol Nutr Food Res 54:S112-9. 2010
    ..The results suggested that increased plasma PL n-3 PUFA, 20:5n-3, 22:6n-3 and ratio of n-3:n-6 PUFA was associated with decreased HOMA-IR in type 2 diabetes. Increased plasma PL n-3 PUFA improves insulin sensitivity in type 2 diabetes...
  21. doi request reprint Low docosahexaenoic acid content in plasma phospholipids is associated with increased non-alcoholic fatty liver disease in China
    Ju Sheng Zheng
    Department of Food Science and Nutrition, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
    Lipids 47:549-56. 2012
    ..41 (95 % CI = 0.17-0.97) compared with the lowest quartile. In conclusion, plasma PL total SFA and C20:3n-6 are positively correlated with the risk of NAFLD, while C22:6n-3 is negatively correlated with the risk of NAFLD...
  22. doi request reprint Platycodin D2 improves specific cellular and humoral responses to hepatitis B surface antigen in mice
    Yong Xie
    Key Laboratory of Animal Epidemic Etiology and Immunological Prevention of the Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310029, P R China
    Chem Biodivers 7:178-85. 2010
    ..The results suggest that 1 could improve both cellular and humoral immune responses to HBsAg in mice. Hence, 1 might be a promising adjuvant for hepatitis B vaccine with dual Th1- and Th2-potentiating activity...
  23. pmc Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits
    Ju Sheng Zheng
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, United States of America
    PLoS ONE 8:e77442. 2013
    ..In conclusion, we utilized a novel method that demonstrates the importance of genome-wide GxE interactions in explaining the variance of diabetes-related traits...
  24. ncbi request reprint Systematic review and meta-analysis of soy products consumption in patients with type 2 diabetes mellitus
    Bin Yang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Asia Pac J Clin Nutr 20:593-602. 2011
    ..04, 0.06; p=0.89). There were no significant effects on fasting glucose, insulin and glycated hemoglobin. It can be concluded that intake of soy and soy products has beneficial effects in T2DM patients in relation to serum lipids...
  25. doi request reprint Combination of fucoxanthin and conjugated linoleic acid attenuates body weight gain and improves lipid metabolism in high-fat diet-induced obese rats
    Xiaojie Hu
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Arch Biochem Biophys 519:59-65. 2012
    ....
  26. doi request reprint Fish consumption and CHD mortality: an updated meta-analysis of seventeen cohort studies
    Jusheng Zheng
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou 310029, People s Republic of China
    Public Health Nutr 15:725-37. 2012
    ..Results of studies on fish consumption and CHD mortality are inconsistent. The present updated meta-analysis was conducted to investigate the up-to-date pooling effects...
  27. doi request reprint Plasma phospholipids n-3 polyunsaturated fatty acid is associated with metabolic syndrome
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, PR China
    Mol Nutr Food Res 54:1628-35. 2010
    ..44, 95% CI = 1.60-7.39) than the subjects with low levels of PL total FA. Our results suggest that plasma PL n-3 PUFA was significantly inversely associated with MS, while high total FA were positively associated with MS in Chinese...
  28. pmc Modulation by dietary fat and carbohydrate of IRS1 association with type 2 diabetes traits in two populations of different ancestries
    Ju Sheng Zheng
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Diabetes Care 36:2621-7. 2013
    ..Insulin receptor substrate 1 (IRS1) is central to insulin signaling pathways. This study aimed to examine the association of IRS1 variants with insulin resistance (IR) and related phenotypes, as well as potential modification by diet...
  29. doi request reprint Low and high homocysteine are associated with mortality independent of B group vitamins but interactive with cognitive status in a free-living elderly cohort
    Li Li Xiu
    Department of Food and Nutritional Science, Zhejiang University, Hangzhou, Zhejiang, China
    Nutr Res 32:928-39. 2012
    ..Yet cognition is inter-related with homocysteine in its association with survival in ways not detectably altered by foods or food-derived vitamins...
  30. pmc Marine N-3 polyunsaturated fatty acids are inversely associated with risk of type 2 diabetes in Asians: a systematic review and meta-analysis
    Ju Sheng Zheng
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    PLoS ONE 7:e44525. 2012
    ..The differences in tissue n-3 PUFA compositions in subjects with and without T2D were investigated based on cohort and case-control studies...
  31. ncbi request reprint Uric acid status and its correlates in Hangzhou urban population
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Asia Pac J Clin Nutr 15:102-6. 2006
    ....
  32. doi request reprint Comparison of lipid content and Fatty Acid composition in the edible meat of wild and cultured freshwater and marine fish and shrimps from china
    Guipu Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, Zhejiang Province, China 310029
    J Agric Food Chem 59:1871-81. 2011
    ..Two freshwater fish, including bighead carp and silver carp, are comparable to the marine fish as sources of n-3 PUFA...
  33. ncbi request reprint Effect of diacylglycerol on body weight: a meta-analysis
    Tongcheng Xu
    Department if Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Asia Pac J Clin Nutr 17:415-21. 2008
    ..044, R2 = 0.889). In conclusion, this meta-analysis suggested that DAG was efficacious for reducing body weight compared with TAG and this effect was influenced by the daily dose...
  34. pmc Effect of polyunsaturated fatty acids on homocysteine metabolism through regulating the gene expressions involved in methionine metabolism
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310059, China
    ScientificWorldJournal 2013:931626. 2013
    ..mRNA expression of Mthfr, Mat1a, Cbs and Pemt, Gnmt, Mtrr, and Bad is upregulated by n-3 PUFA and downregulated by n-6 PUFA. CLA upregulates mRNA expression of Mat1a and Cbs...
  35. doi request reprint Comparative effects of sandalwood seed oil on fatty acid profiles and inflammatory factors in rats
    Guipu Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, 310058 Zhejiang, China
    Lipids 48:105-13. 2013
    ..The present results suggest that sandalwood seed oil could increase tissue levels of n-3 PUFA, DHA and reduce the n-6:n-3 ratio, and may increase the anti-inflammatory activity in rats...
  36. pmc Curcumin-supplemented diets increase superoxide dismutase activity and mean lifespan in Drosophila
    Li Rong Shen
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, 310058, China
    Age (Dordr) 35:1133-42. 2013
    ..This study provided new insights for understanding the anti-aging mechanism of curcumin in Drosophila...
  37. doi request reprint Effects of green tea, black tea, and coffee consumption on the risk of esophageal cancer: a systematic review and meta-analysis of observational studies
    Ju Sheng Zheng
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Nutr Cancer 65:1-16. 2013
    ..non/lowest coffee consumption against EC risk was found (OR = 0.88; 95% CI: 0.76, 1.01). In conclusion, our data showed that both green tea and coffee consumption, but not black tea consumption, have protective effects on EC...
  38. doi request reprint Associations of plasma phospholipid fatty acids with plasma homocysteine in Chinese vegetarians
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, 866 Yuhangtang Road, Hangzhou, People s Republic of China
    Br J Nutr 109:1688-94. 2013
    ..Plasma PL SFA were positively associated with the prevalence of HHcy. It would seem appropriate for vegetarians to increase their dietary n-3 PUFA and decrease dietary SFA, and thus reduce the risk of HHcy...
  39. doi request reprint Meta-analysis of B vitamin supplementation on plasma homocysteine, cardiovascular and all-cause mortality
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310029, PR China
    Clin Nutr 31:448-54. 2012
    ..The aim of the present study was to systematically review the effects of B vitamin supplementation on plasma homocysteine (Hcy), cardiovascular and all-cause mortality in RCT...
  40. ncbi request reprint Plasma phospholipid polyunsaturated fatty acids and homocysteine in Chinese type 2 diabetes patients
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Asia Pac J Clin Nutr 21:394-9. 2012
    ..Our results suggested that increased plasma Hcy levels in T2DM associated with low n-3:n-6 ratio intake. We suggest that T2DM increase their long chain n-3 PUFA intake from fish or fish oil while decrease n-6 PUFA intake...
  41. pmc Methylenetetrahydrofolate reductase variants associated with hypertension and cardiovascular disease interact with dietary polyunsaturated fatty acids to modulate plasma homocysteine in puerto rican adults
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, 310029 China
    J Nutr 141:654-9. 2011
    ..66% energy). Our study suggests that dietary PUFA intake modulates the effect of 2 MTHFR variants on plasma Hcy in Boston Puerto Rican adults...
  42. doi request reprint Myricetin induces G2/M phase arrest in HepG2 cells by inhibiting the activity of the cyclin B/Cdc2 complex
    Xiao Hong Zhang
    Department of Food Science and Nutrition, Zhejiang University, Zhejiang 310029, P R China
    Mol Med Rep 4:273-7. 2011
    ..This novel finding provides insight into the potential applications of myricetin in the treatment of hepatocellular carcinoma...
  43. doi request reprint Platycodin d improves the immunogenicity of newcastle disease virus-based recombinant avian influenza vaccine in mice
    Yong Xie
    Key Laboratory of Animal Epidemic Etiology and Immunological Prevention of the Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310029, P R China
    Chem Biodivers 7:677-89. 2010
    ..We concluded that 1 could improve the immunogenicity of the rL-H5 vaccine by enhancing both humoral and cellular immune responses in mice, and that 1 is a promising adjuvant for influenza vaccines...
  44. doi request reprint Associations of plasma n-3 polyunsaturated fatty acids with blood pressure and cardiovascular risk factors among Chinese
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou, China
    Int J Food Sci Nutr 63:667-73. 2012
    ..Our results suggest that plasma PL n-3 PUFA was significantly inversely associated with hypertension in Chinese. It would seem appropriate for hypertensive subjects to increase their dietary n-3 PUFA which may help reduce BP...
  45. doi request reprint High consumption of Ω-3 polyunsaturated fatty acids decrease plasma homocysteine: a meta-analysis of randomized, placebo-controlled trials
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Nutrition 27:863-7. 2011
    ..The objective was to systematically evaluate the effects of ω-3 PUFA supplementation on plasma Hcy levels...
  46. doi request reprint Cardiovascular disease mortality and cancer incidence in vegetarians: a meta-analysis and systematic review
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Ann Nutr Metab 60:233-40. 2012
    ..Prospective cohort studies have examined mortality and overall cancer incidence among vegetarians, but the results have been inconclusive...
  47. doi request reprint Incorporation and metabolism of punicic acid in healthy young humans
    Gaofeng Yuan
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Mol Nutr Food Res 53:1336-42. 2009
    ..Edible TK seeds could be a potential dietary source of conjugated linoleic acids...
  48. ncbi request reprint Hyperuricemia and the metabolic syndrome in Hangzhou
    Zhenzhen Cai
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, Zhejiang, China
    Asia Pac J Clin Nutr 18:81-7. 2009
    ..234, p<0.0001). Results suggest that increased serum uric acid concentration is associated with an increased prevalence of metabolic disorders such as obesity, dyslipidemia and hypertension in the Hangzhou population...
  49. doi request reprint Intake of fish and marine n-3 polyunsaturated fatty acids and risk of breast cancer: meta-analysis of data from 21 independent prospective cohort studies
    Ju Sheng Zheng
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310058, China
    BMJ 346:f3706. 2013
    ..To investigate the association between intake of fish and n-3 polyunsaturated fatty acids (n-3 PUFA) and the risk of breast cancer and to evaluate the potential dose-response relation...
  50. ncbi request reprint Ganoderma lucidum polysaccharides exert anti-hyperglycemic effect on streptozotocin-induced diabetic rats through affecting β-cells
    Jusheng Zheng
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Comb Chem High Throughput Screen 15:542-50. 2012
    ..The present results suggested that Gl-PS had a hypoglycemic effect in STZ-induced diabetic rats through preventing apoptosis of pancreatic β-cells and enhancing β-cells regeneration...
  51. ncbi request reprint Omega 6 to omega 3 fatty acid imbalance early in life leads to persistent reductions in DHA levels in glycerophospholipids in rat hypothalamus even after long-term omega 3 fatty acid repletion
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310029, China
    Prostaglandins Leukot Essent Fatty Acids 74:391-9. 2006
    ..The increased ALA and reduced DHA proportions in the animals re-fed ALA in later life are consistent with a dysfunction or down-regulation of the conversion of ALA to 18:4n-3 by the delta-6 desaturase...
  52. doi request reprint Seasonal variation in nutrient composition of Mytilus coruscus from China
    Guipu Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, Zhejiang, China 310029
    J Agric Food Chem 58:7831-7. 2010
    ..Cultivated Chinese thick shell mussels represent a source of the health benefiting long chain n-3 PUFA, essential amino acids, and minerals for human consumption...
  53. doi request reprint Induction of apoptosis by tomato using space mutation breeding in human colon cancer SW480 and HT-29 cells
    Jiahui Shi
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    J Sci Food Agric 90:615-21. 2010
    ..The aim of this study was to evaluate the anti-colon cancer effect of tomatoes M1 and M2 using space mutation breeding...
  54. pmc Effects of krill oil on serum lipids of hyperlipidemic rats and human SW480 cells
    Jia Jin Zhu
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, PR China
    Lipids Health Dis 7:30. 2008
    ..Serum lipids of rats fed with high fat diet (HFD) and different doses of KO were measured by automatic analyzer. Effect of KO on viability of cells was determined by methyl thiazolyl tetrazolium (MTT) assay...
  55. pmc Effects of Chinese liquors on cardiovascular disease risk factors in healthy young humans
    Ju Sheng Zheng
    Department of Food Science and Nutrition, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
    ScientificWorldJournal 2012:372143. 2012
    ..To elucidate whether consumption of two Chinese liquors, tea-flavor liquor (TFL) and traditional Chinese liquor (TCL) have protective effects on cardiovascular disease (CVD) risk factors in healthy human subjects...
  56. doi request reprint Docosahexaenoic acid decreases plasma homocysteine via regulating enzyme activity and mRNA expression involved in methionine metabolism
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Nutrition 26:112-9. 2010
    ..The objective of this study was to investigate the regulatory effect of fish oil rich in omega-3 polyunsaturated fatty acids (PUFAs) on critical enzyme activity and mRNA expression involved in homocysteine (Hcy) metabolism...
  57. ncbi request reprint Securing food from field to table: what can we do?
    Duo Li
    Department of Food Science and Nutrition, Zhejiang University, China
    Asia Pac J Clin Nutr 20:149-50. 2011
    ..To increase their prospects for sustainability and health promotion, coordinated partnerships between agriculture and health as well as other sectors are imperative...
  58. doi request reprint Effect of diacylglycerol on postprandial serum triacylglycerol concentration: a meta-analysis
    Tongcheng Xu
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, 310029 Hangzhou, China
    Lipids 44:161-8. 2009
    ..095) and 6 h (P = 0.053) after lipid loading. In conclusion, compared with TAG oil, DAG reduced the postprandial serum TAG concentration at 2 h, 4 h and 6 h postprandial and was positively correlated with daily dosage...
  59. doi request reprint Effect of Marine-Derived n-3 Polyunsaturated Fatty Acids on C-Reactive Protein, Interleukin 6 and Tumor Necrosis Factor α: A Meta-Analysis
    Kelei Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China APCNS Centre of Nutrition and Food Safety, Hangzhou, China
    PLoS ONE 9:e88103. 2014
    ....
  60. doi request reprint Anti-inflammatory activity and mechanism of a lipid extract from hard-shelled mussel (Mytilus coruscus) on chronic arthritis in rats
    Guipu Li
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310058, Zhejiang, China
    Mar Drugs 12:568-88. 2014
    ....
  61. ncbi request reprint Cardiovascular pathogenesis in hyperhomocysteinemia
    Tao Huang
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Rd, Hangzhou, Zhejiang, 310029, P R China
    Asia Pac J Clin Nutr 17:8-16. 2008
    ..The mechanisms involved in the increased risk of cardiovascular disease still remains a mystery in many respects, and more studies are needed to elucidate this association...
  62. ncbi request reprint Diet rich in saturated fat decreases the ratio of thromboxane/prostacyclin in healthy men
    Duo Li
    Department of Food Science, Hangzhou University of Commerce, Hangzhou 310035, Zhejiang, China
    Biomed Environ Sci 16:333-9. 2003
    ..To investigate the effect of dietary saturated fat (SFA) from animal sources on the urine excretion 11-dehydro thromboxane B2 (TXB2) and 6-keto prostaglandin F 1alpha (PGF 1alpha) in 27 healthy free-living male subjects aged 30 to 55 years...
  63. ncbi request reprint Nutritional evaluation of different bacterial douchi
    Hua Li
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou, Zhejiang, China 310029
    Asia Pac J Clin Nutr 16:215-21. 2007
    ..Composition of lipids, fatty acids, and amino acids were no significant change after soybean bacterial fermentation...
  64. doi request reprint Soy fiber improves weight loss and lipid profile in overweight and obese adults: a randomized controlled trial
    Xiaojie Hu
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, P R China
    Mol Nutr Food Res 57:2147-54. 2013
    ..This study examined the effects of soy fiber (SF) on body weight, body composition, and blood lipids in overweight and obese participants...
  65. doi request reprint DHA prevents altered 5-HT1A, 5-HT2A, CB1 and GABAA receptor binding densities in the brain of male rats fed a high-saturated-fat diet
    Yinghua Yu
    Illawarra Health and Medical Research Institute, School of Health Sciences, University of Wollongong, Wollongong, NSW 2522, Australia
    J Nutr Biochem 24:1349-58. 2013
    ..These findings provide insight into the mechanism by which DHA supplementation ameliorates reduced cognitive function associated with an HF diet...
  66. doi request reprint Green tea and black tea consumption and prostate cancer risk: an exploratory meta-analysis of observational studies
    Jusheng Zheng
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    Nutr Cancer 63:663-72. 2011
    ..Further research regarding green tea consumption across different regions apart from Asia is needed...
  67. pmc Expression of a bee venom phospholipase A2 from Apis cerana cerana in the baculovirus-insect cell
    Li Rong Shen
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310029, China
    J Zhejiang Univ Sci B 11:342-9. 2010
    ..These findings provided fundamental knowledge for potential genetic engineering to produce AccPLA(2) in the pharmaceutical industry...
  68. doi request reprint Expression of Acc-Royalisin gene from royal jelly of Chinese honeybee in Escherichia coli and its antibacterial activity
    Lirong Shen
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou, Zhejiang, China
    J Agric Food Chem 58:2266-73. 2010
    ..MAR peptide released from the thrombin-cleaved GST-MAR fusion protein has a stronger antibacterial activity than that of GST-MAR fusion protein...
  69. ncbi request reprint [Research on discrimination method of tomato via space mutation breeding based on spectroscopy technology]
    Jia Hui Shi
    College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310029, China
    Guang Pu Xue Yu Guang Pu Fen Xi 29:2943-6. 2009
    ..The discrimination rate of 97.8% was achieved by this method. It offered a new approach to the fast discrimination of varieties of tomato via space mutation breeding...
  70. pmc Drosophila lacks C20 and C22 PUFAs
    Li Rong Shen
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China
    J Lipid Res 51:2985-92. 2010
    ..These findings demonstrate that Drosophila lacks the capability to synthesize the biologically important C20 and C22 PUFAs, and thereby argue that Drosophila is not a valid model for the study of lipid metabolism and related diseases...
  71. doi request reprint Optimization of medium constituents for ε-poly-L-lysine fermentation with response surface methodology
    Hong Zong
    Dept of Food Science and Nutrition, Huajiachi Campus, Zhejiang Univ, Hangzhou, China
    J Food Sci 75:M552-6. 2010
    ..5; FeSO(4), 0.03; ZnSO(4), 0.04; KH(2)PO(4), 1.36; and Na(2)HPO(4).12H(2)O, 3.58. When cultured in the optimum medium, the ε-PL production was an average of 0.349 ± 0.025 mg/mL, which was 1.75 times higher than the initial medium...
  72. ncbi request reprint Natural products and anti-inflammatory activity
    Gaofeng Yuan
    Department of Food Science and Nutrition, Zhejiang University, 268 Kaixuan Road, Hangzhou, Zhejiang, China 310029
    Asia Pac J Clin Nutr 15:143-52. 2006
    ..Further studies are being conducted to investigate the mechanism of action, metabolism, safety and long term side effect of these natural products, as well as interactions between these natural products with food and drug components...
  73. ncbi request reprint A novel dual PI3Kalpha/mTOR inhibitor PI-103 with high antitumor activity in non-small cell lung cancer cells
    Zu Quan Zou
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, PR China
    Int J Mol Med 24:97-101. 2009
    ..Collectively, our results suggest that multitargeted intervention is the most effective tumor therapy, and the cooperative blockade of PI3Kalpha and mTOR with PI-103 shows promise for treating gefitinib-resistant NSCLC...
  74. ncbi request reprint The presence of hepatitis B surface antigen in the ova of pregnant women and its relationship with intra-uterine infection by hepatitis B virus
    H Lou
    Department of Obstetrics, Zhejiang University, Hangzhou, China
    J Int Med Res 38:214-9. 2010
    ..These findings indicate that vertical transmission via oocytes may not be the major route of HBV intra-uterine infection...
  75. ncbi request reprint Bread enriched with microencapsulated tuna oil increases plasma docosahexaenoic acid and total omega-3 fatty acids in humans
    Yolande L Yep
    Department of Food Science, RMIT University, Melbourne, Victoria, Australia
    Asia Pac J Clin Nutr 11:285-91. 2002
    ..05) at the endpoint compared with the baseline. This study showed that a low dose of LC n-3 PUFA, consumed as MTO-enriched bread, was bioavailable, as measured by an increase in LC n-3 PUFA levels in the plasma of human subjects...
  76. ncbi request reprint Fatty acid composition of habitual omnivore and vegetarian diets
    Neil Mann
    Department of Food Science, Lipid Research Group, School of Applied Science, RMIT University, Melbourne 3001, Australia
    Lipids 41:637-46. 2006
    ..Thus, accurate dietary and plasma FA analyses suggest that regular moderate consumption of meat and fish maintains a plasma FA profile possibly more conducive to good health...
  77. ncbi request reprint Effects of gamma-tocopherol supplementation on thrombotic risk factors
    Indu Singh
    Division of Laboratory Medicine, School of Medical Sciences, RMIT University, PO Box 71, Bundoora, Victoria 3083, Australia
    Asia Pac J Clin Nutr 16:422-8. 2007
    ..We determined the effect of 5 weeks of 100 mg/d or 200 mg/d gamma-T supplementation on thrombotic markers such as platelet reactivity, lipid profile and the inflammation marker C-reactive protein (CRP)...
  78. ncbi request reprint Relationship between platelet phospholipid FA and mean platelet volume in healthy men
    Duo Li
    Department of Food Science, RMIT University, Melbourne 3001, Australia
    Lipids 37:901-6. 2002
    ..003) and 22:5n-3 (P = 0.001). The present data suggest that 22:5n-3 and 20:3n-6 may play a role in the structural function of the platelet membrane...
  79. ncbi request reprint [Relations of platelet phospholipid fatty acids to thrombotic risk factors in middle-aged and geriatric patients with hyperlipidemia]
    Xiao Mei Yu
    Department of Clinical Laboratory, Zhejiang Hospital, Hangzhou 310013, China
    Zhonghua Yi Xue Za Zhi 87:105-8. 2007
    ..To investigate the relations of platelet phospholipid fatty acids to thrombotic risk factors in the middle-aged and geriatric patients with hyperlipidemia in the metropolitan area of Hangzhou, Zhejiang province...
  80. ncbi request reprint What is the role of alpha-linolenic acid for mammals?
    Andrew J Sinclair
    Department of Food Science, RMIT University, Melbourne, Victoria, 3001, Australia
    Lipids 37:1113-23. 2002
    ..Additionally, we must not forget that ALA is part of the whole diet and should be seen in this context, not in isolation...
  81. ncbi request reprint alpha-linolenic acid and the risk of prostate cancer
    Nadia M Attar-Bashi
    Lipids 39:929-32. 2004
  82. ncbi request reprint Omega-3 fatty acids and non-communicable diseases
    Duo Li
    Department of Food Science, Hangzhou University of Commerce, Hangzhou 310035, China
    Chin Med J (Engl) 116:453-8. 2003
    ..To review the relation between dietary omega-3 polyunsaturated fatty acids (omega-3 PUFA) and non-communicable diseases...
  83. ncbi request reprint The food industry and provincial economies
    Greg Walsh
    HEC Foods Pty Ltd, Warrnambool, Australia
    Asia Pac J Clin Nutr 13:166-70. 2004
    ....