Feihe Huang


Affiliation: Zhejiang University
Country: China


  1. Yu G, Wu D, Li Y, Zhang Z, Shao L, Zhou J, et al. A pillar[5]arene-based [2]rotaxane lights up mitochondria. Chem Sci. 2016;7:3017-3024 pubmed publisher
    ..The anticancer drugs are released from these prodrugs in the cells upon hydrolysis of the pH-responsive imine bonds. ..
  2. Yu G, Zhou J, Shen J, Tang G, Huang F. Cationic pillar[6]arene/ATP host-guest recognition: selectivity, inhibition of ATP hydrolysis, and application in multidrug resistance treatment. Chem Sci. 2016;7:4073-4078 pubmed publisher
    ..This supramolecular method provides an extremely distinct strategy to potentially overcome multidrug resistance (MDR). ..
  3. Ji X, Ahmed M, Long L, Khashab N, Huang F, Sessler J. Adhesive supramolecular polymeric materials constructed from macrocycle-based host-guest interactions. Chem Soc Rev. 2019;: pubmed publisher
    ..An overview of future challenges and a perspective of this sub-field are also provided. ..
  4. Zhou Y, Jie K, Huang F. A dual redox-responsive supramolecular amphiphile fabricated by selenium-containing pillar[6]arene-based molecular recognition. Chem Commun (Camb). 2018;54:12856-12859 pubmed publisher
    ..A dual redox-responsive pillar[6]arene-based supramolecular amphiphile was fabricated in water. The self-assembly behavior of this supramolecular amphiphile in response to dual redox stimuli was investigated. ..
  5. Ji X, Chen W, Long L, Huang F, Sessler J. Double layer 3D codes: fluorescent supramolecular polymeric gels allowing direct recognition of the chloride anion using a smart phone. Chem Sci. 2018;9:7746-7752 pubmed publisher
    ..The present sensing strategy does not rely on elaborate instrumentation and could provide a new application for elaborated soft materials. ..
  6. Yu G, Yu S, Saha M, Zhou J, Cook T, Yung B, et al. A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy. Nat Commun. 2018;9:4335 pubmed publisher
    ..Gene chip analyses confirmed the contribution of different therapeutic modalities to the tumor abrogation. This supramolecular platform holds potential in precise cancer theranostics. ..
  7. Wei P, Yan X, Huang F. Reversible formation of a poly[3]rotaxane based on photo dimerization of an anthracene-capped [3]rotaxane. Chem Commun (Camb). 2014;50:14105-8 pubmed publisher
    ..We prepared a poly[3]rotaxane consisting of a ''topologically linked polymer backbone'' in one pot from readily available, modular building blocks via a dynamic polymerization strategy based on reversible anthracene dimerization. ..
  8. Zhou J, Yu G, Shao L, Hua B, Huang F. A water-soluble biphen[3]arene: synthesis, host-guest complexation, and application in controllable self-assembly and controlled release. Chem Commun (Camb). 2015;51:4188-91 pubmed publisher
    ..The first water-soluble biphen[3]arene has been synthesized. Its pH-responsive host-guest complexation with secondary ammonium salts in water and application in controllable self-assembly and controlled release have been investigated. ..
  9. Xia D, Wei P, Shi B, Huang F. A pillar[6]arene-based [2]pseudorotaxane in solution and in the solid state and its photo-responsive self-assembly behavior in solution. Chem Commun (Camb). 2016;52:513-6 pubmed publisher
    ..A pillar[6]arene-based [2]pseudorotaxane was constructed in solution and studied in the solid state, and its photo-responsive self-assembly behavior in solution was investigated. ..

More Information


  1. Jie K, Zhou Y, Yao Y, Huang F. Macrocyclic amphiphiles. Chem Soc Rev. 2015;44:3568-87 pubmed publisher
    ..Moreover, the interactions of their self-assemblies can be mediated by molecular recognition, which may further our understanding of biological processes. ..
  2. Wei P, Li D, Shi B, Wang Q, Huang F. An anthracene-appended 2:3 copillar[5]arene: synthesis, computational studies, and application in highly selective fluorescence sensing for Fe(III) ions. Chem Commun (Camb). 2015;51:15169-72 pubmed publisher
    ..Herein an anthracene-appended 2:3 copillar[5]arene was prepared by the CuAAC method, which was further used as a Fe(3+)-selective fluorescent chemosensor over a wide range of metal ions. ..
  3. Yu G, Yang Z, Fu X, Yung B, Yang J, Mao Z, et al. Polyrotaxane-based supramolecular theranostics. Nat Commun. 2018;9:766 pubmed publisher
    ..These supramolecular nanomedicines also exhibit excellent anti-tumour performance against orthotopic breast cancer and prevent lung metastasis with negligible systemic toxicity. ..
  4. Hua B, Shao L, Yu G, Huang F. Fluorescence indicator displacement detection based on pillar[5]arene-assisted dye deprotonation. Chem Commun (Camb). 2016;52:10016-9 pubmed publisher
    ..Fluorescence indicator displacement detection based on pillar[5]arene-assisted dye deprotonation was reported. ..
  5. Wei P, Wang H, Jie K, Huang F. Taco complex-templated highly regio- and stereo-selective photodimerization of a coumarin-containing crown ether. Chem Commun (Camb). 2017;53:1688-1691 pubmed publisher
    ..Preorientation of the terminal coumarins of a crown ether with the assistance of taco-type host-guest complex formation promotes regio- and stereo-selectivity of coumarin photodimerization to give only the syn head-to-tail coumarin isomer. ..
  6. Zhou Y, Jie K, Huang F. A redox-responsive selenium-containing pillar[5]arene-based macrocyclic amphiphile: synthesis, controllable self-assembly in water, and application in controlled release. Chem Commun (Camb). 2017;53:8364-8367 pubmed publisher
    ..This amphiphile self-assembled in water to form vesicles with redox responsiveness. Furthermore, these pillar[5]arene-based vesicles were used in the controlled release of small molecules with DOX as the model compound. ..
  7. Shangguan L, Chen Q, Shi B, Huang F. Enhancing the solubility and bioactivity of anticancer drug tamoxifen by water-soluble pillar[6]arene-based host-guest complexation. Chem Commun (Camb). 2017;53:9749-9752 pubmed publisher
    ..A water-soluble pillar[6]arene functions as a solubilizing agent to enhance the solubility and bioactivity of poorly water-soluble anticancer drug tamoxifen by host-guest complexation between it and tamoxifen. ..