Xiaohui Fan

Summary

Affiliation: Zhejiang University
Country: China

Publications

  1. pmc Evaluation of the potential sensitization of chlorogenic Acid: a meta-analysis
    Mingbao Lin
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
    Evid Based Complement Alternat Med 2013:208467. 2013
  2. pmc Determination of minimum training sample size for microarray-based cancer outcome prediction-an empirical assessment
    Li Shao
    Pharmaceutical Informatics Institute, School of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 8:e68579. 2013
  3. pmc T2D@ZJU: a knowledgebase integrating heterogeneous connections associated with type 2 diabetes mellitus
    Zhenzhong Yang
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Database (Oxford) 2013:bat052. 2013
  4. ncbi request reprint Dissecting active ingredients of Chinese medicine by content-weighted ingredient-target network
    Linli Wang
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Mol Biosyst 10:1905-11. 2014
  5. pmc A network pharmacology approach to evaluating the efficacy of chinese medicine using genome-wide transcriptional expression data
    Leihong Wu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Evid Based Complement Alternat Med 2013:915343. 2013
  6. pmc CHD@ZJU: a knowledgebase providing network-based research platform on coronary heart disease
    Leihong Wu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Database (Oxford) 2013:bat047. 2013
  7. pmc Chemometric analysis for identification of botanical raw materials for pharmaceutical use: a case study using Panax notoginseng
    Jieqiang Zhu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 9:e87462. 2014
  8. ncbi request reprint [Network toxicology and its application to traditional Chinese medicine]
    Xiaohui Fan
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 36:2920-2. 2011
  9. pmc Chemical fingerprinting and quantitative analysis of a Panax notoginseng preparation using HPLC-UV and HPLC-MS
    Hong Yao
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, China
    Chin Med 6:9. 2011
  10. pmc Investigation of reproducibility of differentially expressed genes in DNA microarrays through statistical simulation
    Xiaohui Fan
    National Center for Toxicological Research NCTR, US Food and Drug Administration, 3900 NCTR Rd, Jefferson, AR 72079, USA
    BMC Proc 3:S4. 2009

Collaborators

Detail Information

Publications55

  1. pmc Evaluation of the potential sensitization of chlorogenic Acid: a meta-analysis
    Mingbao Lin
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
    Evid Based Complement Alternat Med 2013:208467. 2013
    ....
  2. pmc Determination of minimum training sample size for microarray-based cancer outcome prediction-an empirical assessment
    Li Shao
    Pharmaceutical Informatics Institute, School of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 8:e68579. 2013
    ..Once translated into clinical routine applications, the SSNR-based protocol would provide great convenience in microarray-based cancer outcome prediction in improving classifier reliability. ..
  3. pmc T2D@ZJU: a knowledgebase integrating heterogeneous connections associated with type 2 diabetes mellitus
    Zhenzhong Yang
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Database (Oxford) 2013:bat052. 2013
    ..The functionality of T2D@ZJU is shown by means of several case studies. Database URL: http://tcm.zju.edu.cn/t2d...
  4. ncbi request reprint Dissecting active ingredients of Chinese medicine by content-weighted ingredient-target network
    Linli Wang
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Mol Biosyst 10:1905-11. 2014
    ..In conclusion, this study presented a novel approach to identify active ingredients in Chinese medicine. ..
  5. pmc A network pharmacology approach to evaluating the efficacy of chinese medicine using genome-wide transcriptional expression data
    Leihong Wu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Evid Based Complement Alternat Med 2013:915343. 2013
    ..The successful application of SHENMAI implied that the proposed network pharmacology-based approach could help researchers to better evaluate a multicomponent drug on a systematic and molecular level...
  6. pmc CHD@ZJU: a knowledgebase providing network-based research platform on coronary heart disease
    Leihong Wu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Database (Oxford) 2013:bat047. 2013
    ..Database URL: http://tcm.zju.edu.cn/chd/ ..
  7. pmc Chemometric analysis for identification of botanical raw materials for pharmaceutical use: a case study using Panax notoginseng
    Jieqiang Zhu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 9:e87462. 2014
    ....
  8. ncbi request reprint [Network toxicology and its application to traditional Chinese medicine]
    Xiaohui Fan
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 36:2920-2. 2011
    ..The related tools and technologies have been briefly introduced, and the prospects for network toxicology of traditional Chinese medicine are forecasted...
  9. pmc Chemical fingerprinting and quantitative analysis of a Panax notoginseng preparation using HPLC-UV and HPLC-MS
    Hong Yao
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, China
    Chin Med 6:9. 2011
    ..abstract:..
  10. pmc Investigation of reproducibility of differentially expressed genes in DNA microarrays through statistical simulation
    Xiaohui Fan
    National Center for Toxicological Research NCTR, US Food and Drug Administration, 3900 NCTR Rd, Jefferson, AR 72079, USA
    BMC Proc 3:S4. 2009
    ..We conclude that the MAQC recommendation should be considered when reproducibility is an important study objective...
  11. doi request reprint Toxicogenomic analysis of the particle dose- and size-response relationship of silica particles-induced toxicity in mice
    Xiaoyan Lu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, People s Republic of China
    Nanotechnology 24:015106. 2013
    ....
  12. pmc Shifting from population-wide to personalized cancer prognosis with microarrays
    Li Shao
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 7:e29534. 2012
    ..Ascribing a confidence level to prognosis with the clinical confidence metric provides the clinician an objective, personalized basis for decisions, such as choosing the severity of the treatment...
  13. pmc Cross-platform comparison of microarray-based multiple-class prediction
    Xiaohui Fan
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 6:e16067. 2011
    ..Further studies are needed to confirm the feasibility of microarray-based cross-platform prediction, especially using independent datasets...
  14. doi request reprint Structure-activity differences of chlorogenic acid and its isomers on sensitization via intravenous exposure
    Mingbao Lin
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    Int J Toxicol 31:602-10. 2012
    ..In summary, when administered intravenously, the strength and type of sensitization may be correlated with structure differences in the CGA family...
  15. pmc A Network Pharmacology Study of Chinese Medicine QiShenYiQi to Reveal Its Underlying Multi-Compound, Multi-Target, Multi-Pathway Mode of Action
    Xiang Li
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 9:e95004. 2014
    ..Finally, through a three-level compound-target-pathway network with experimental analysis, our study depicts a complex MOA of QSYQ on myocardial infarction. ..
  16. doi request reprint DNA microarrays are predictive of cancer prognosis: a re-evaluation
    Xiaohui Fan
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    Clin Cancer Res 16:629-36. 2010
    ..We set to investigate the reality of microarrays for predicting cancer prognosis by using the same data sets with commonly accepted data analysis approaches...
  17. doi request reprint Integrated analysis of transcriptomics and metabonomics profiles in aflatoxin B1-induced hepatotoxicity in rat
    Xiaoyan Lu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Food Chem Toxicol 55:444-55. 2013
    ..The genes and metabolites significantly affected in common in rat liver or serum of three doses AFB1 treatments served as potential biomarkers for detecting AFB1-induced acute hepatotoxicity...
  18. doi request reprint Proteomic study on usnic-acid-induced hepatotoxicity in rats
    Qian Liu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, People s Republic of China
    J Agric Food Chem 60:7312-7. 2012
    ..These proteins are associated with oxidative stress, lipid metabolism, and several other molecular pathways. The endoplasmic reticulum and mitochondria may be the primary targets of usnic-acid-induced hepatotoxicity...
  19. doi request reprint Integrated systems toxicology approaches identified the possible involvement of ABC transporters pathway in erythromycin estolate-induced liver injury in rat
    Xiaoyan Lu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Food Chem Toxicol 65:343-55. 2014
    ..In addition, EE-induced liver injury was also related to alteration in glycogen and sucrose metabolism, arachidonic acid metabolism, and linoleic acid metabolism pathways. ..
  20. ncbi request reprint Metabolite profiling and pharmacokinetics of herbal compounds following oral administration of a cardiovascular multi-herb medicine (Qishen yiqi pills) in rats
    Yufeng Zhang
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, P R China
    Curr Drug Metab 13:510-23. 2012
    ..The PK results showed that their maximal concentrations in blood were obtained within one hour, much shorter than the reported values in single herbs. The rat exposure was proximately linear under the studied dosages from 1 to 6 g/kg...
  21. ncbi request reprint [Symptom-based traditional Chinese medicine slices relationship network and its network pharmacology study]
    Leihong Wu
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 36:2916-9. 2011
    ..To discover and interpret the correlations between traditional Chinese medicine (TCM) slices and their properties such as function, symptom and channel tropism by constructing the relationship network using network pharmacology approaches...
  22. doi request reprint Correlation analysis of external RNA controls reveals its utility for assessment of microarray assay
    Xiaohui Fan
    National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA
    Anal Biochem 385:203-7. 2009
    ..The proposed approach is sensitive to identifying outlying assays and is not dependent on the choice of normalization method...
  23. ncbi request reprint Self-self hybridization as an alternative experiment design to dye swap for two-color microarrays
    Hong Fang
    Division of Bioinformatics, Z Tech Corporation, Jefferson, Arkansas, USA
    OMICS 11:14-24. 2007
    ..For example, in larger toxicogenomic studies, only about half the chips are required for the self-self hybridization design compared to that needed in the dye swap design...
  24. doi request reprint Enhanced QSAR model performance by integrating structural and gene expression information
    Qian Chen
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Molecules 18:10789-801. 2013
    ..Our successful integration of biological information into classic QSAR model provided a new insight and methodology for building predictive models especially when QSAR paradox occurred. ..
  25. ncbi request reprint [Prediction of multi-target of Aconiti Lateralis Radix Praeparata and its network pharmacology]
    Leihong Wu
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 36:2907-10. 2011
    ..To predict multi-targets by multi-compounds found in Aconiti Lateralis Radix Praeparata and construct the corresponding multi-compound-multi-target network...
  26. doi request reprint A three-stage-integrative approach for the identification of potential hepatotoxic compounds from botanical products
    Yecheng Jin
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou, P R China
    Int J Toxicol 30:287-99. 2011
    ..These applications suggested that our TSI approach provides an effective tool for identifying potential toxic compounds from botanical products...
  27. doi request reprint An intravenous exposure mouse model for prediction of potential drug-sensitization using reporter antigens popliteal lymph node assay
    Mingbao Lin
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    J Appl Toxicol 32:395-401. 2012
    ..In addition, there was no marked reaction with the negative compound. Together, it seems likely that the intravenous exposure model may be useful for drug-induced systemic hypersensitivity assessments...
  28. doi request reprint Relating anatomical therapeutic indications by the ensemble similarity of drug sets
    Leihong Wu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    J Chem Inf Model 53:2154-60. 2013
    ....
  29. pmc The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models
    Leming Shi
    National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas, USA
    Nat Biotechnol 28:827-38. 2010
    ..The conclusions and recommendations from MAQC-II should be useful for regulatory agencies, study committees and independent investigators that evaluate methods for global gene expression analysis...
  30. pmc Does applicability domain exist in microarray-based genomic research?
    Li Shao
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 5:e11055. 2010
    ..We found that the issue of applicability domain may not exist in microarray-based genomic research for clinical applications. Therefore, it is not practicable to improve model validity based on applicability domain...
  31. doi request reprint Decision forest for classification of gene expression data
    Jianping Huang
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, 388 Yuhangtang Road, Hangzhou 310058, China
    Comput Biol Med 40:698-704. 2010
    ..Moreover, it suffers less from the curse of dimensionality...
  32. ncbi request reprint [Tools for network pharmacology study: network visualization and network analysis]
    Leihong Wu
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 36:2923-5. 2011
    ..In this paper, we generally showed the work flow of network pharmacology research, and introduced concepts of network visualization and network analysis, as well the commonly-used tools, such as Cytoscape...
  33. ncbi request reprint LTMap: a web server for assessing the potential liver toxicity by genome-wide transcriptional expression data
    Li Xing
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China
    J Appl Toxicol 34:805-9. 2014
    ..Furthermore, a user-friendly web interface is provided by LTMap to browse and search toxicogenomics data (http://tcm.zju.edu.cn/ltmap)...
  34. doi request reprint Untargeted metabolic profiling reveals potential biomarkers in myocardial infarction and its application
    Hong Yao
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, PR China
    Mol Biosyst 6:1061-70. 2010
    ....
  35. ncbi request reprint [Network pharmacology study on major active compounds of Fufang Danshen formula]
    Xiang Li
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 36:2911-5. 2011
    ..To investigate the correlations between multi-compounds of Fufang Danshen formula and their multi targets and multi diseases...
  36. doi request reprint Cardioprotective effects of Glycyrrhiza uralensis extract against doxorubicin-induced toxicity
    Ling Zhang
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou, P R China
    Int J Toxicol 30:181-9. 2011
    ..Additionally, GUE did not compromise the tumor-inhibitory effect of DOX. In conclusion, our studies imply the potentially clinical application of GUE to overcome the cardiotoxicity of doxorubicin...
  37. ncbi request reprint Strategies and techniques for multi-component drug design from medicinal herbs and traditional Chinese medicine
    Yi Wang
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou, 310058, China
    Curr Top Med Chem 12:1356-62. 2012
    ..Meanwhile, clinical knowledge of TCM provides a promising framework for multi-component drug design. A renaissance of multi-component drug discovery inspired by traditional medicine is possible...
  38. doi request reprint A metabonomic characterization of (+)-usnic acid-induced liver injury by gas chromatography-mass spectrometry-based metabolic profiling of the plasma and liver in rat
    Xiaoyan Lu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058 People s Republic of China
    Int J Toxicol 30:478-91. 2011
    ..The significant changes in 22 metabolites in liver might be adopted as potential biomarkers...
  39. ncbi request reprint [Serum metabolome analysis reveals effect of panax notoginosides on ischemic rat after acute myocardial infarction]
    Jin Wang
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 35:3199-202. 2010
    ..The effect of panax notoginosides on ischemic rat after acute myocardial infarction by coronary artery ligation was preliminarily investigated using metabonomics approach...
  40. ncbi request reprint Development of fluorescence imaging-based assay for screening cardioprotective compounds from medicinal plants
    Yi Wang
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, PR China
    Anal Chim Acta 702:87-94. 2011
    ..These applications suggested that the proposed rapid and sensitive screening approach offers an efficient way to discover active components or compounds from medicinal plants...
  41. ncbi request reprint [Discovering active components from traditional Chinese medicine by component-knockout approach]
    Lingyan Yu
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 34:336-9. 2009
    ..A component-knockout approach was established to discover active components from traditional Chinese medicine...
  42. ncbi request reprint Identification of the effective constituents for anti-inflammatory activity of Ju-Zhi-Jiang-Tang, an ancient traditional Chinese medicine formula
    Shufang Wang
    Pharmaceutical Informatics Institute, Zhejiang University, Zijingang Campus, No 866 Yuhangtang Road, Hangzhou 310058, PR China Electronic address
    J Chromatogr A 1348:105-24. 2014
    ..In conclusion, our results indicated the proposed approach might be an efficient and rapid way to identify active constituents of TCM formulae. ..
  43. pmc A three step network based approach (TSNBA) to finding disease molecular signature and key regulators: a case study of IL-1 and TNF-alpha stimulated inflammation
    Jihong Yang
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 9:e94360. 2014
    ..The rest 9 were also validated with TF (transcription factor) binding site analysis. In conclusion, we developed an efficient strategy for disease molecular signature finding and key pathological regulator identification. ..
  44. ncbi request reprint [Inhibitory effects of astragaloside IV on cytochrome P450 enzyme of rat liver microsomes]
    Wenya Shan
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 37:85-8. 2012
    ..To provide a scientific basis for the drug-combination and aim to examine whether astragaloside IV has the impact on the cytochrome P450 enzymes...
  45. doi request reprint Consensus ranking approach to understanding the underlying mechanism with QSAR
    Li Shao
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    J Chem Inf Model 50:1941-8. 2010
    ..Moreover, the consistently inferior model performance using descriptors selected for mechanistic analysis suggested the irreplaceable role of model development in achieving models with the best predictive capability...
  46. ncbi request reprint A pharmacokinetic and pharmacodynamic study of drug-drug interaction between ginsenoside Rg1, ginsenoside Rb1 and schizandrin after intravenous administration to rats
    Shuyu Zhan
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    J Ethnopharmacol 152:333-9. 2014
    ..It is valuable to investigate their pharmacokinetic and pharmacodynamic behavior and potential synergistic effect for better drug development and clinical application...
  47. doi request reprint Systematic characterisation of secondary metabolites from Ixeris sonchifolia by the combined use of HPLC-TOFMS and HPLC-ITMS
    Peiying Shi
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, People s Republic of China
    Phytochem Anal 22:66-73. 2011
    ..Ixeris sonchifolia (Bunge) Hance, a folk medicine, has been widely used in China for its anti-inflammatory and haemostatic effects. However, the miscellaneous component composition of this herbal medicine is not well known...
  48. doi request reprint Virtual separation of phytochemical constituents by their adduct-ion patterns in full mass spectra
    Yufeng Zhang
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    J Chromatogr A 1227:181-93. 2012
    ..The proposed tool provides a novel approach for processing the LC/MS datasets of complex samples, such as traditional Chinese medicine and botanical drugs...
  49. doi request reprint Why QSAR fails: an empirical evaluation using conventional computational approach
    Jianping Huang
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Mol Pharm 8:600-8. 2011
    ....
  50. ncbi request reprint Evaluation of external RNA controls for the assessment of microarray performance
    Weida Tong
    National Center for Toxicological Research, US Food and Drug Administration, 3900 NCTR Rd, Jefferson, Arkansas 72079, USA
    Nat Biotechnol 24:1132-9. 2006
    ..This multiplatform investigation of the behavior and utility of ERCs provides a basis for articulating specific recommendations for their future use in evaluating assay performance across multiple platforms...
  51. ncbi request reprint A pre-classification strategy for identification of compounds in traditional Chinese medicine analogous formulas by high-performance liquid chromatography-Mass spectrometry
    Shun Xiao
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    J Pharm Biomed Anal 92:82-9. 2014
    ..Additionally, we carried out the chemical differentiation study of this formula group, which was reported for the first time and would be useful to further pharmacological studies. ..
  52. doi request reprint Reliably assessing prediction reliability for high dimensional QSAR data
    Jianping Huang
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    Mol Divers 17:63-73. 2013
    ..A free version of TreeEC with a user-friendly interface can also be downloading from website http://pharminfo.zju.edu.cn/computation/TreeEC/TreeEC.html...
  53. doi request reprint 2012 Global Summit on Regulatory Science (GSRS-2012)--modernizing toxicology
    Margaret A Miller
    National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas 72079, USA
    Toxicol Sci 131:9-12. 2013
    ....
  54. ncbi request reprint [Simultaneous characterization of two types of major active components in Kushen by high performance liquid chromatography coupled to multi-stage mass spectrometry]
    Qinqin Zhao
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 36:762-9. 2011
    ....