Yi Yu Cheng

Summary

Affiliation: Zhejiang University
Country: China

Publications

  1. ncbi request reprint Phthalide Lactones from Ligusticum chuanxiong inhibit lipopolysaccharide-induced TNF-alpha production and TNF-alpha-mediated NF-kappaB Activation
    Li Liu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P R China
    Planta Med 71:808-13. 2005
  2. pmc Shifting from population-wide to personalized cancer prognosis with microarrays
    Li Shao
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 7:e29534. 2012
  3. pmc Cross-platform comparison of microarray-based multiple-class prediction
    Xiaohui Fan
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 6:e16067. 2011
  4. ncbi request reprint [Innovation guidelines and strategies for pharmaceutical engineering of Chinese medicine and their industrial translation]
    Yi Yu Cheng
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 38:3-5. 2013
  5. ncbi request reprint Strategies and techniques for multi-component drug design from medicinal herbs and traditional Chinese medicine
    Yi Wang
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou, 310058, China
    Curr Top Med Chem 12:1356-62. 2012
  6. ncbi request reprint Quantitative study of electrostatic and steric effects on physicochemical property and biological activity
    Yi Yu Cheng
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    J Mol Graph Model 24:219-26. 2006
  7. ncbi request reprint An approach to comparative analysis of chromatographic fingerprints for assuring the quality of botanical drugs
    Yiyu Cheng
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    J Chem Inf Comput Sci 43:1068-76. 2003
  8. ncbi request reprint Fractal fingerprinting of chromatographic profiles based on wavelet analysis and its application to characterize the quality grade of medicinal herbs
    Cheng Yiyu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    J Chem Inf Comput Sci 43:1959-65. 2003
  9. ncbi request reprint A causal relationship discovery-based approach to identifying active components of herbal medicine
    Yiyu Cheng
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    Comput Biol Chem 30:148-54. 2006
  10. ncbi request reprint [Determination of salvianolic acid B and paeoniflorin in Shuangdan granules by HPLC]
    Zhi Wei Ge
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    Zhongguo Zhong Yao Za Zhi 31:1062-4. 2006

Collaborators

Detail Information

Publications57

  1. ncbi request reprint Phthalide Lactones from Ligusticum chuanxiong inhibit lipopolysaccharide-induced TNF-alpha production and TNF-alpha-mediated NF-kappaB Activation
    Li Liu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P R China
    Planta Med 71:808-13. 2005
    ..New insights into the therapeutic basis of the TCM herb, Ligusticum chuanxiong, are presented...
  2. pmc Shifting from population-wide to personalized cancer prognosis with microarrays
    Li Shao
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 7:e29534. 2012
    ..Ascribing a confidence level to prognosis with the clinical confidence metric provides the clinician an objective, personalized basis for decisions, such as choosing the severity of the treatment...
  3. pmc Cross-platform comparison of microarray-based multiple-class prediction
    Xiaohui Fan
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 6:e16067. 2011
    ..Further studies are needed to confirm the feasibility of microarray-based cross-platform prediction, especially using independent datasets...
  4. ncbi request reprint [Innovation guidelines and strategies for pharmaceutical engineering of Chinese medicine and their industrial translation]
    Yi Yu Cheng
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 38:3-5. 2013
    ..The prospects of the pharmaceutical technology are also forecasted...
  5. ncbi request reprint Strategies and techniques for multi-component drug design from medicinal herbs and traditional Chinese medicine
    Yi Wang
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou, 310058, China
    Curr Top Med Chem 12:1356-62. 2012
    ..Meanwhile, clinical knowledge of TCM provides a promising framework for multi-component drug design. A renaissance of multi-component drug discovery inspired by traditional medicine is possible...
  6. ncbi request reprint Quantitative study of electrostatic and steric effects on physicochemical property and biological activity
    Yi Yu Cheng
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    J Mol Graph Model 24:219-26. 2006
    ..9530 and s = 0.206 for the toxicity of substituted phenols against tetrahymena pyriformis. Leave-one-out cross validation was also carried out to evaluate the stability of each model and good results were obtained...
  7. ncbi request reprint An approach to comparative analysis of chromatographic fingerprints for assuring the quality of botanical drugs
    Yiyu Cheng
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    J Chem Inf Comput Sci 43:1068-76. 2003
    ..The methods are equally applicable to other botanical drugs...
  8. ncbi request reprint Fractal fingerprinting of chromatographic profiles based on wavelet analysis and its application to characterize the quality grade of medicinal herbs
    Cheng Yiyu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    J Chem Inf Comput Sci 43:1959-65. 2003
    ..0% of the herbs are correctly identified with respect to their quality grades determined by pharmacodynamical evaluation...
  9. ncbi request reprint A causal relationship discovery-based approach to identifying active components of herbal medicine
    Yiyu Cheng
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    Comput Biol Chem 30:148-54. 2006
    ..The current work offers a new way to virtually screen active components of herbal medicine, and it might be helpful to accelerate the process of new drug discovery from natural products...
  10. ncbi request reprint [Determination of salvianolic acid B and paeoniflorin in Shuangdan granules by HPLC]
    Zhi Wei Ge
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    Zhongguo Zhong Yao Za Zhi 31:1062-4. 2006
    ..To develop a method for the determination of salvianolic acid B and paeoniflorin in Shuangdan granules...
  11. ncbi request reprint [Application of HPLC/ELSD fingerprint and constellation graphical clustering method applied to evaluate the quality of Qingkailing injection]
    Shi Kai Yan
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    Yao Xue Xue Bao 40:842-5. 2005
    ..To evaluate the quality of Qingkailing injections effectively, and to develop a credible method for the quality control of traditional Chinese medicine...
  12. ncbi request reprint [Study on quality control of effective fraction in qixue bingzhi decoction]
    Zai Fang Huang
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    Zhongguo Zhong Yao Za Zhi 30:580-3. 2005
    ..To develop a method for quality control of effective fraction in Qi-Xue-Bing-Zhi decoction, a traditional Chinese medicine (TCM)...
  13. ncbi request reprint Determination of paeonol and paeoniflorin in Chinese medicine Cortex Moutan and 'Shuangdan' granule by micellar electrokinetic capillary chromatography
    Ke Yu
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    J Pharm Biomed Anal 40:1257-62. 2006
    ..The method was successfully applied to the determination of these two components contained in Cortex Moutan and 'Shuangdan' granule. The average recoveries ranged between 97.6 and 105.3% for PN and 95.3 and 106.1% for PF, respectively...
  14. ncbi request reprint Analysis of 'SHUANGDAN' granules by high-performance liquid chromatography-diode array detection-electrospray ionization tandem mass spectrometry
    Qing He
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310027, People s Republic of China
    J Pharm Biomed Anal 41:485-92. 2006
    ..This method was rapid and reliable for identification of constituents in complex chemical system, 'SHUANGDAN' granules, and the newly fragmentation patterns proposed could be extended to the compounds elucidation with similar framework...
  15. ncbi request reprint [The effect of preparation method on the quality of shen-mai injection]
    Yong Jiang Wu
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    Zhongguo Zhong Yao Za Zhi 30:662-5. 2005
    ..To investigate the effect of different preparation method on the quality of Shen-mai injection...
  16. ncbi request reprint Simultaneous determination of major bioactive components in Qingkailing injection by high-performance liquid chromatography with evaporative light scattering detection
    Shi Kai Yan
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    Chem Pharm Bull (Tokyo) 53:1392-5. 2005
    ..The proposed method is a useful alternative for routine analysis in the quality control of traditional Chinese medicine...
  17. ncbi request reprint [Optimizing process of four-effect countercurrent extraction of danshensu from Salvia miltiorrhiza]
    Ming Cai
    Department of Chinese Medicine Sciences and Engineering, Zhejiang University, Hangzhou 310027, China
    Zhongguo Zhong Yao Za Zhi 31:1499-502. 2006
    ..To investigate the process factors and characteristic of four-effect countercurrent extracting process of Danshensu from Salvia miltiorrhiza. Optimizing the parameters by using regression analysis and principal components analysis (PCA)...
  18. ncbi request reprint [A chromatographic fingerprinting-based approach to evaluating the stability of production process of traditional Chinese medicine]
    Chu Chu Hu
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou, China
    Zhongguo Zhong Yao Za Zhi 31:1151-4, 1162. 2006
    ..To study a new method for the evaluation of the stability of production process of Traditional Chinese Medicines (TCM) based on chromatographic fingerprinting...
  19. ncbi request reprint Quality evaluation of cortex moutan by high performance liquid chromatography coupled with diode array detector and electrospary ionization tandem mass spectrometry
    Qing He
    Department of Chinese Medicine Science and Engineering, Zhejiang University, 148 Tianmushan Road, Hangzhou 310027, People s Republic of China
    Chem Pharm Bull (Tokyo) 54:1271-5. 2006
    ..This developed method that combined the chromatographic fingerprints and quantification assay ensured the phytoequivalence and pharmacological effects of Cortex Moutan and was successfully applied to the quality control of Cortex Moutan...
  20. ncbi request reprint [Simultaneous determination of three active constituents in cortex moutan by RP-HPLC]
    Yu wen Wang
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    Zhongguo Zhong Yao Za Zhi 31:1699-701. 2006
    ..To establish a RP-HPLC method for the simultaneous determination of gallic acid, paeoniflorin and paeonol in Cortex Moutan...
  21. ncbi request reprint Simple method for determination of five terpenoids from different parts of Tripterygium wilfordii and its preparations by HPLC coupled with evaporative light scattering detection
    Xiao Ling Luo
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    J Sep Sci 30:1284-91. 2007
    ....
  22. ncbi request reprint [A method for predicting activity of traditional Chinese medicine based on quantitative composition-activity relationship of neural network model]
    Xiao Ping Zhao
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Zhongguo Zhong Yao Za Zhi 29:1082-5. 2004
    ..To study a method for evaluating the quality of traditional Chinese medicine (TCM) according as their activity...
  23. ncbi request reprint [Study on the solubility changes of Rhizoma Coptidis' main chemical constituents influenced by the proportion of Rhizoma Coptidis and Fructus Evodiae]
    Ming Xing Peng
    Department of Chinese Medine Science and Engineering, Zhejiang University, Hangzhou 310027, Zhejiang, China
    Zhongguo Zhong Yao Za Zhi 28:629-32. 2003
    ..To investigate the relationship between the solubility of Rhizoma Coptidis' main chemical constituents and the proportion of Rhizoma Coptidis and Fructus Evodiae...
  24. pmc Background correction in near-infrared spectra of plant extracts by orthogonal signal correction
    Hai Bin Qu
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310027, China
    J Zhejiang Univ Sci B 6:838-43. 2005
    ..A simulated dataset and a real NIR spectral dataset were used to test the efficiency of different background correction methods. The results showed that OSC is the only effective method for correcting excessive background...
  25. ncbi request reprint [Simultaneous determination of 4 anthraquinones in Kuhuang injection by RP-HPLC]
    Yong Jiang Wu
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027
    Zhongguo Zhong Yao Za Zhi 29:1041-4. 2004
    ..To develop a new high-performance liquid chromatographic method for simultaneous quantitative determination of 4 anthraquinones in Kuhuang injection...
  26. ncbi request reprint [Identification of the habitat of Ligusticum chuangxiong with chromatographic fingerprinting]
    Min Jun Chen
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310027, Zhejiang, China
    Zhongguo Zhong Yao Za Zhi 28:606-10. 2003
    ..To establish the chromatographic fingerprinting for identifying the habitat of Ligusticum chuangxiong...
  27. ncbi request reprint Identification and analysis of absorbed and metabolic components in rat plasma after oral administration of 'Shuangdan' granule by HPLC-DAD-ESI-MS/MS
    Jian Yang Pan
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, People s Republic of China
    J Pharm Biomed Anal 42:565-72. 2006
    ..The results proved that the established method could be used to identify the structure of active components responsible for the pharmacological effects of 'Shuangdan' granule...
  28. ncbi request reprint Binary chromatographic fingerprinting for quality evaluation of Radix Ophiopogonis by high-performance liquid chromatography coupled with ultraviolet and evaporative light-scattering detectors
    Li Liu
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    J Sep Sci 30:2628-37. 2007
    ..The method was validated and applied to quality evaluation of 16 samples of Radix Ophiopogonis and related herbs...
  29. ncbi request reprint [Advances in studies on multi-stage countercurrent extraction technology in traditional Chinese medicine]
    Zhi Peng Xie
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Zhongguo Zhong Yao Za Zhi 32:884-7. 2007
    ..This paper reviewed the basic principle, the influence factors and the research progress and trends of the equipments and the application of the multi-stage countercurrent extraction...
  30. ncbi request reprint [A novel fingerprint method for quality evaluation of Chinese medicinal plants based on analytical data visualization]
    Jie Yu
    Institute of Pharmaceutical Engineering, College of Material Science and Chemical Engineering, Zhejiang University, Hangzhou 310027, Zhejiang, China
    Zhongguo Zhong Yao Za Zhi 27:97-100. 2002
    ..To investigate new method for evaluating the quality of Chinese Medicinal Plants (CMP)...
  31. ncbi request reprint [Some engineering problems on developing production industry of modern traditional Chinese medicine]
    Hai Bin Qu
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310027, Zhejiang, China
    Zhongguo Zhong Yao Za Zhi 28:904-6, 939. 2003
    ..Accelerating the application and extension of high-tech and computer integrated manufacturing system (CIMS) were suggested to promote the technology advancement of TCM industry...
  32. ncbi request reprint Simultaneous determination of ginsenosides in Panax ginseng with different growth ages using high-performance liquid chromatography-mass spectrometry
    Yi Wang
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, People s Republic of China
    Phytochem Anal 17:424-30. 2006
    ..Ginseng can be harvested after the fourth year. The current results will provide useful information for the quality control and good agricultural practice farming of ginseng...
  33. ncbi request reprint [Transport mechanism of danshensu across Caco-2 monolayer model]
    Di Feng Zhu
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310027, China
    Zhongguo Zhong Yao Za Zhi 31:1517-21. 2006
    ..To study the absorption mechanism of Danshensu by using Caco-2 monolayer model ...
  34. ncbi request reprint A proteomic study of S-nitrosylation in the rat cardiac proteins in vitro
    Qiang Shi
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    Biol Pharm Bull 31:1536-40. 2008
    ..This study represents an initial attempt to characterize the S-nitrosoproteome in the heart and highlights the importance of protein S-nitrosylation in cardio function regulation...
  35. doi request reprint Micellar electrokinetic chromatography for the quantitative analysis of flavonoids in the radix of Astragalus membranaceus var. mongholicus
    Yue Song
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou, People s Republic of China
    Planta Med 74:84-9. 2008
    ..The relative standard deviations (R.S.D.s) from intra-day and inter-day precision for injection were less than 4.42 %. Six plant samples from different locations were then analyzed for the flavonoids by this newly developed MEKC method...
  36. ncbi request reprint [Advances in pharmaceutical analysis]
    Su Zeng
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 33:1-6. 2004
  37. doi request reprint A method for the production and characterization of fractionated libraries from Chinese herbal formulas
    Li Liu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zijin gang Campus, Zhejiang University, Hangzhou 310058, China
    J Chromatogr B Analyt Technol Biomed Life Sci 862:196-204. 2008
    ..Several bioactive compounds were quickly identified from this library through the screening and dereplication process...
  38. ncbi request reprint An approach to develop two-dimensional fingerprint for the quality control of Qingkailing injection by high-performance liquid chromatography with diode array detection
    Shi Kai Yan
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, PR China
    J Chromatogr A 1090:90-7. 2005
    ..Finally, we demonstrated that 2D fingerprint was a more powerful tool to characterize the quality of samples, and could be used to comprehensively conduct the quality control of traditional Chinese medicines...
  39. ncbi request reprint Mode of action-based local QSAR modeling for the prediction of acute toxicity in the fathead minnow
    Hua Yuan
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    J Mol Graph Model 26:327-35. 2007
    ..Therefore, the MOA-based local QSAR models are promising to improve the accuracy of toxicity prediction as long as the assessment of MOA is of high reliability...
  40. pmc Metabonomic analysis of hepatitis B virus-induced liver failure: identification of potential diagnostic biomarkers by fuzzy support vector machine
    Yong Mao
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China
    J Zhejiang Univ Sci B 9:474-81. 2008
    ..62% predictive accuracy by 6 features was selected with FSVM-ES and three key metabolites, glyceric acid, cis-aconitic acid and citric acid, are identified as potential diagnostic biomarkers...
  41. ncbi request reprint Simultaneous determination of phenylglyoxylic acid, mandelic acid, styrene glycol and hippuric acid in primary culture of rat hepatocytes incubate by high-performance liquid chromatography
    Jin Zhao Wang
    Department of Pharmaceutical Analysis and Drug Metabolism, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang 310031, People s Republic of China
    Biomed Chromatogr 21:497-501. 2007
    ..The extent of biotransformation from S-MA to PGA is significantly greater than that from the R enantiomer and the main metabolites are PGA and HA for S-SG and R-SG, respectively...
  42. ncbi request reprint Capillary high performance liquid chromatography coupled with electrospray ionization mass spectrometry for rapid analysis of pinane monoterpene glycosides in Cortex Moutan
    Yue Song
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou, People s Republic of China
    J Sep Sci 31:64-70. 2008
    ..8 and 101.0%, and good precision values (RSD, 1.2-4.91%) for peak area were obtained. After validation, the applicability of the method for determination of these pinane monoterpene glycosides in cortex Moutan has been demonstrated...
  43. ncbi request reprint An HPLC/MS method for identifying major constituents in the hypocholesterolemic extracts of Chinese medicine formula 'Xue-Fu-Zhu-Yu decoction'
    Hai jiang Zhang
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, People s Republic of China
    Biomed Chromatogr 20:821-6. 2006
    ....
  44. pmc Simultaneous detection of seven phenolic acids in Danshen injection using HPLC with ultraviolet detector
    Jin zhong Xu
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
    J Zhejiang Univ Sci B 9:728-33. 2008
    ..The limit of detection (LOD) was improved to be in the range of 0.008-0.160 microg/ml. Moreover, excellent linear behavior over the investigated concentration range was observed, with R>0.999 for all the analytes...
  45. ncbi request reprint A sensitive and specific HPLC-MS method for the determination of sophoridine, sophocarpine and matrine in rabbit plasma
    Yong Jiang Wu
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, P R China
    Anal Bioanal Chem 382:1595-600. 2005
    ..1, 6.3 and 5.8% for SRI, SC and MT, respectively. The developed method was applied to determine the concentration-time profiles of SRI, SC and MT in rabbit plasma after injection of Kuhuang...
  46. ncbi request reprint [Applications of chitosan and its derivatives in pharmaceutical industry of Chinese medicine]
    Long Hu Wang
    Department of Chinese Medicine Sciences and Engineering, Zhejiang University, Hangzhou 310027, China
    Zhongguo Zhong Yao Za Zhi 29:289-92. 2004
    ..Chitosan and its derivatives wide application prosperity in pharmaceutical industry of Chinese medicine...
  47. ncbi request reprint [Recent advance in predicting oral bioavailability]
    Guang Li Ma
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310027, China
    Yao Xue Xue Bao 41:917-20. 2006
  48. ncbi request reprint [Simultaneous determination of water-soluble components and nerolidol in xiangdan injection by high performance liquid chromatography with column switching]
    Qian Lu
    Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 33:2776-80. 2008
    ..The concentrations of water-soluble components in Xiangdan injection are roughly 1000 times of that of nerolidol...
  49. doi request reprint Two new compounds from Senecio cannabifolius
    Yi Tao
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    J Asian Nat Prod Res 14:826-30. 2012
    ..Compounds 1 and 2 were evaluated for inhibitory activity against lipopolysaccharide-induced NO production in RAW 264.7 macrophages, and compound 1 showed potent inhibitory activity with IC(50) value of 30.65 μM...
  50. ncbi request reprint [Effects of Radix Ginseng and Radix Ophiopogonis extract (SMF) on protein S-nitrosylation in ischemic myocardial tissue]
    Jin hong Feng
    Zhejiang University, Department of Chinese Medicine Science and Engineering, Hangzhou 310058, China
    Zhongguo Zhong Yao Za Zhi 33:1894-7. 2008
    ..To observe the effect of Radix Ginseng and Radix Ophiopogonis extract (SMF) on protein S-nitrosylation in rats myocardial with ischemia/reperfusion injury (MI/RI)...
  51. ncbi request reprint Chemodiversity of saponins and their taxonomic importance in Clematis genus (Ranunculaceae)
    C Muhammad Ishtiaq
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Institute of Bioinformatics, Zhejiang University, No 38, Zhe da Road Hangzhou, 310027, People s Republic of China
    Pak J Biol Sci 10:2066-72. 2007
    ..The morphological analysis was also conducted of the same taxa and presented as cluster tree. The distribution and chemotaxonomic importance of saponins profile within the genus is discussed...
  52. ncbi request reprint [Optimization for vacuum belt drying process of Panax notoginseng extract]
    Xue Song Liu
    Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Zhongguo Zhong Yao Za Zhi 33:385-8. 2008
    ..To optimize the conditions of the vacuum belt drying process (VBD) for drying Panax notoginseng extract and compare with methods of vacuum freezing drying and spray drying...
  53. doi request reprint Distinct effects of naringenin and hesperetin on nitric oxide production from endothelial cells
    Li Liu
    College of Pharmaceutical Sciences, Zhejiang University, Zijin gang Campus, Hangzhou 310058, China
    J Agric Food Chem 56:824-9. 2008
    ..Our findings add more proof to the molecular explanations for the health benefits of citrus used to prevent cardiovascular disease, especially for postmenopausal women...
  54. ncbi request reprint [Quantitative analysis of the nucleosides in Cordyceps sinensis with capillary zone electrophoresis]
    Xiao Rong Hou
    Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Science, Zhejiang University, Hangzhou 310027, China
    Zhongguo Zhong Yao Za Zhi 30:447-9. 2005
    ..To establish a quantitative analysis method for analyzing the nucleosides in Cordyceps sinensis with capillary electrophoresis, and compare the difference between natural and the cultured C. mycelia...
  55. ncbi request reprint Chemical constituents from the roots of Ranunculus ternatus
    Jing Kui Tian
    Department of Chinese Medicine Sciences and Engineering, Zhejiang University, Hangzhou 310028, People s Republic of China
    J Asian Nat Prod Res 8:35-9. 2006
    ....
  56. ncbi request reprint [Effects of water extractives of a qi and blood regulating prescription on early atherosclerosis of apolipoprotein E-deficient mice]
    Guo ju Dong
    Department of Cardiology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China
    Zhong Xi Yi Jie He Xue Bao 5:45-9. 2007
    ....
  57. doi request reprint A pilot study of GC/MS-based serum metabolic profiling of acute rejection in renal transplantation
    You Ying Mao
    Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, PR China
    Transpl Immunol 19:74-80. 2008
    ..How are serum metabolite levels in response to acute rejection? Can metabolite levels in serum be used to diagnose and explain acute renal allograft rejection?..