Zhigang Zhao

Summary

Country: China

Publications

  1. ncbi Complete androgen ablation suppresses prostate stem cell antigen (PSCA) mRNA expression in human prostate carcinoma
    Zhao Zhigang
    Department of Urology, The Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong Province, China
    Prostate 65:299-305. 2005
  2. ncbi Serum insulin-like growth factor I/free prostate specific antigen (IGF-I/fPSA) ratio enhances prostate cancer detection in men with total PSA 4.0-10.0 ng/ml
    Zhao Zhigang
    Department of Urology, The Second Affiliated Hospital, Shantou University Medical, College, Shantou, Guangdong Province, China
    J Surg Oncol 96:54-61. 2007
  3. pmc Serum early prostate cancer antigen (EPCA) level and its association with disease progression in prostate cancer in a Chinese population
    Zhigang Zhao
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangdong Provincial Key Laboratory of Urology, Guangzhou, Guangdong Province, China
    PLoS ONE 6:e19284. 2011
  4. doi Small interference RNA-mediated silencing of prostate stem cell antigen attenuates growth, reduces migration and invasion of human prostate cancer PC-3M cells
    Zhigang Zhao
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangdong Key Laboratory of Urology, Guangzhou, China
    Urol Oncol 31:343-51. 2013
  5. pmc Clinical utility of the UPOINT phenotype system in Chinese males with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS): a prospective study
    Zhigang Zhao
    Department of Urology and Andrology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangdong Provincial Key Laboratory of Urology, Guangzhou, Guangdong Province, China
    PLoS ONE 8:e52044. 2013
  6. doi Peripheral blood reverse transcription PCR assay for prostate stem cell antigen correlates with androgen-independent progression in advanced prostate cancer
    Zhigang Zhao
    Department of Urology, The First Affiliated Hospital of Guangzhou Medical College, Guangdong Province, China
    Int J Cancer 131:902-10. 2012
  7. doi Preoperative serum levels of early prostate cancer antigen (EPCA) predict prostate cancer progression in patients undergoing radical prostatectomy
    Zhigang Zhao
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangdong Key Laboratory of Urology, Guangzhou, Guangdong Province, China
    Prostate 72:270-9. 2012
  8. doi Serum early prostate cancer antigen (EPCA) as a significant predictor of incidental prostate cancer in patients undergoing transurethral resection of the prostate for benign prostatic hyperplasia
    Zhigang Zhao
    Department of Urology of Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, Guangdong Province, China
    Prostate 70:1788-98. 2010
  9. doi PSCA mRNA expression in preoperatively negative prostate biopsies predicts incidental prostate cancer in patients undergoing transurethral resection of the prostate for benign prostatic hyperplasia
    Zhigang Zhao
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital, Guangzhou Medical College, Guangzhou, Guangdong Province, China
    J Surg Oncol 104:672-8. 2011
  10. doi Prostate stem cell antigen mRNA expression in preoperatively negative biopsy specimens predicts subsequent cancer after transurethral resection of the prostate for benign prostatic hyperplasia
    Zhigang Zhao
    Department of Urology, The Second Affiliated Hospital, Shantou University Medical College, Guangdong Province, China
    Prostate 69:1292-302. 2009

Collaborators

Detail Information

Publications27

  1. ncbi Complete androgen ablation suppresses prostate stem cell antigen (PSCA) mRNA expression in human prostate carcinoma
    Zhao Zhigang
    Department of Urology, The Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong Province, China
    Prostate 65:299-305. 2005
    ..The purpose of the present study was to investigate the variations in the expression levels of PSCA mRNA before and after CAA, and further evaluate the clinically prognostic value of PSCA in human prostate carcinoma...
  2. ncbi Serum insulin-like growth factor I/free prostate specific antigen (IGF-I/fPSA) ratio enhances prostate cancer detection in men with total PSA 4.0-10.0 ng/ml
    Zhao Zhigang
    Department of Urology, The Second Affiliated Hospital, Shantou University Medical, College, Shantou, Guangdong Province, China
    J Surg Oncol 96:54-61. 2007
    ..This study was to investigate the use of serum IGF-I and IGFBP-3, and their combinations with prostate volume and fPSA in enhancing the discriminatory diagnosis of PCa in men with tPSA of 4.0-10.0 ng/ml...
  3. pmc Serum early prostate cancer antigen (EPCA) level and its association with disease progression in prostate cancer in a Chinese population
    Zhigang Zhao
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangdong Provincial Key Laboratory of Urology, Guangzhou, Guangdong Province, China
    PLoS ONE 6:e19284. 2011
    ..The goals of this study are to measure serum EPCA levels in a cohort of patients with PCa prior to the treatment, and to evaluate the clinical value of serum EPCA...
  4. doi Small interference RNA-mediated silencing of prostate stem cell antigen attenuates growth, reduces migration and invasion of human prostate cancer PC-3M cells
    Zhigang Zhao
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangdong Key Laboratory of Urology, Guangzhou, China
    Urol Oncol 31:343-51. 2013
    ..The purpose of the current study is to investigate the therapeutic potential of small interference RNA (siRNA) targeting PSCA on human CaP cells...
  5. pmc Clinical utility of the UPOINT phenotype system in Chinese males with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS): a prospective study
    Zhigang Zhao
    Department of Urology and Andrology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangdong Provincial Key Laboratory of Urology, Guangzhou, Guangdong Province, China
    PLoS ONE 8:e52044. 2013
    ..We also investigated the addition of an ED domain in regard to symptom correlation...
  6. doi Peripheral blood reverse transcription PCR assay for prostate stem cell antigen correlates with androgen-independent progression in advanced prostate cancer
    Zhigang Zhao
    Department of Urology, The First Affiliated Hospital of Guangzhou Medical College, Guangdong Province, China
    Int J Cancer 131:902-10. 2012
    ..303, 95% CI: 3.761-7.482, p < 0.001). Pretreatment RT-PCR PSCA positivity in peripheral blood independently signals the presence of AIP in patients with advanced PCa treated with ADT...
  7. doi Preoperative serum levels of early prostate cancer antigen (EPCA) predict prostate cancer progression in patients undergoing radical prostatectomy
    Zhigang Zhao
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangdong Key Laboratory of Urology, Guangzhou, Guangdong Province, China
    Prostate 72:270-9. 2012
    ....
  8. doi Serum early prostate cancer antigen (EPCA) as a significant predictor of incidental prostate cancer in patients undergoing transurethral resection of the prostate for benign prostatic hyperplasia
    Zhigang Zhao
    Department of Urology of Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, Guangdong Province, China
    Prostate 70:1788-98. 2010
    ..This study was to determine whether preoperative serum EPCA levels predicted the presence of incidental prostate cancer (IPCa) in patients undergoing TURP for BPH...
  9. doi PSCA mRNA expression in preoperatively negative prostate biopsies predicts incidental prostate cancer in patients undergoing transurethral resection of the prostate for benign prostatic hyperplasia
    Zhigang Zhao
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital, Guangzhou Medical College, Guangzhou, Guangdong Province, China
    J Surg Oncol 104:672-8. 2011
    ..This study was to determine whether PSCA mRNA expression in preoperatively negative biopsies identified the presence of incidental prostate cancer (IPCa) on TURP tissues analysis...
  10. doi Prostate stem cell antigen mRNA expression in preoperatively negative biopsy specimens predicts subsequent cancer after transurethral resection of the prostate for benign prostatic hyperplasia
    Zhigang Zhao
    Department of Urology, The Second Affiliated Hospital, Shantou University Medical College, Guangdong Province, China
    Prostate 69:1292-302. 2009
    ..This study was to determine whether PSCA mRNA positivity in preoperatively negative prostatic biopsy samples from BPH men with PSA > 4.0 ng/ml and/or suspicious DRE findings had predictive performance following TURP...
  11. ncbi The association of prostate stem cell antigen (PSCA) mRNA expression and subsequent prostate cancer risk in men with benign prostatic hyperplasia following transurethral resection of the prostate
    Zhao Zhigang
    Department of Urology, The Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong Province, China
    Prostate 68:190-9. 2008
    ..The purpose of the present investigation was to determine whether PSCA mRNA expression in resected BPH samples was associated with the subsequent presence of cancer following transurethral resection of the prostate (TURP)...
  12. ncbi Flutamide reduced prostate cancer development and prostate stem cell antigen mRNA expression in high grade prostatic intraepithelial neoplasia
    Zhao Zhigang
    Department of Urology, The Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong Province, China
    Int J Cancer 122:864-70. 2008
    ....
  13. ncbi Prostate stem cell antigen (PSCA) mRNA expression in prostatic intraepithelial neoplasia: implications for the development of prostate cancer
    Zhao Zhigang
    Department of Urology, The Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong Province, China
    Prostate 67:1143-51. 2007
    ..The purpose of the present investigation was to determine whether PSCA mRNA expression was associated with the presence of cancer in this disease...
  14. ncbi An intrarenal supernumerary ovary concurrent with a completely duplicated pelvis and ureter
    Zhao Zhigang
    Department of Urology, The Second Affiliated Hospital, Shantou University Medical College, Dongxia Northern Road, Shantou, 515041, Guangdong Province, China
    Int Urogynecol J Pelvic Floor Dysfunct 18:1243-6. 2007
    ..In this case report, we present the first case of this lesion, which is concurrent with a completely duplicated pelvis and ureter on the right side...
  15. ncbi External beam radiotherapy (EBRT) suppressed prostate stem cell antigen (PSCA) mRNA expression in clinically localized prostate cancer
    Zhao Zhigang
    Department of Urology, The Second Affiliated Hospital, Shantou University Medical College, Guangdong Province, China
    Prostate 67:653-60. 2007
    ..The purpose of the present study was to investigate the variations in the expression levels of PSCA mRNA before and after EBRT, and further evaluate the prognostic value of PSCA in this disease...
  16. ncbi Heat shock protein 70 antisense oligonucleotide inhibits cell growth and induces apoptosis in human gastric cancer cell line SGC-7901
    Zhi Gang Zhao
    Department of Surgery, Shantou University Medical College, Shantou, Guangdong Province, China
    World J Gastroenterol 11:73-8. 2005
    ..We investigated the effects of antisense HSP70 oligomer on human gastric cancer cell line SGC-7901, and its potential role in gene therapy for this cancer...
  17. ncbi Abrogation of heat-shock protein (HSP)70 expression induced cell growth inhibition and apoptosis in human androgen-independent prostate cancer cell line PC-3m
    Zhi Gang Zhao
    Department of Urology, Shantou University Medical College, 515031, China
    Asian J Androl 6:319-24. 2004
    ..To investigate the effect of abrogating heat shock protein (HSP) 70 expression by antisense HSP70 oligonucleotides treatment on human androgen-independent prostate cancer cell line PC-3m growth...
  18. ncbi Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues: implications for prostate carcinogenesis and progression of prostate cancer
    Zhao Zhigang
    Department of Urology, Shantou University Medical College, Second Affiliated Hospital of Shantou University Medical College, Shantou 515031, Guangdong, China
    Jpn J Clin Oncol 34:414-9. 2004
    ..The objective of the present study was to examine the expression status of PSCA protein and mRNA in clinical specimens of human prostate cancer (PCa) and to validate it as a potential molecular target for diagnosis and treatment of PCa...
  19. doi Increased serum level of early prostate cancer antigen is associated with subsequent cancer risk in men with high-grade prostatic intraepithelial neoplasia
    Zhigang Zhao
    Department of Urology of Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, No 1 3, Kangda Road, Guangzhou 510230, Guangdong Province, People s Republic of China
    Endocr Relat Cancer 17:505-12. 2010
    ..10 absorbance (relative risk, 3.32; 95% confidence intervals, 2.62-5.03, P<0.001). These preliminary findings first show the potential of serum EPCA to serve as a significant predictor for subsequent cancer in isolated HGPIN...
  20. doi Percutaneous nephrolithotomy for renal stones following failed extracorporeal shockwave lithotripsy: different performances and morbidities
    Wen Zhong
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, Guangdong, China
    Urolithiasis 41:165-8. 2013
    ..However, the PCNL procedure was safe and effective in patients with failed SWL. The risk of complications was similar and clearance rate was encouraging...
  21. doi Impact of plasmakinetic enucleation of the prostate (PKEP) on sexual function: results of a prospective trial
    Zhigang Zhao
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, Guangdong Province, China
    J Sex Med 9:1473-81. 2012
    ..Recent data have shown that plasmakinetic enucleation of the prostate (PKEP) is a novel and effective procedure for symptomatic benign prostatic hyperplasia (BPH); however, data on patient sexual function after PKEP remain scarce...
  22. doi Treatment of renal stones in infants: comparing extracorporeal shock wave lithotripsy and mini-percutaneous nephrolithotomy
    Guohua Zeng
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, China
    Urol Res 40:599-603. 2012
    ..In conclusion, MPCNL is an effective and feasible alternative monotherapy for large renal stones (15-25 mm) in infants, with a higher stone-free rate and a lower complication rate when compared with ESWL...
  23. doi A prospective, randomised trial comparing plasmakinetic enucleation to standard transurethral resection of the prostate for symptomatic benign prostatic hyperplasia: three-year follow-up results
    Zhigang Zhao
    Department of Urology, Minimally Invasive Surgery Centre, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, Guangdong Province, China
    Eur Urol 58:752-8. 2010
    ..However, its long-term safety, efficacy, and durability in comparison with the gold-standard transurethral resection of the prostate (TURP) have not yet been reported...
  24. doi Prevalence of diabetes among men and women in China
    Wenying Yang
    China Japan Friendship Hospital, Beijing, China
    N Engl J Med 362:1090-101. 2010
    ..Because of the rapid change in lifestyle in China, there is concern that diabetes may become epidemic. We conducted a national study from June 2007 through May 2008 to estimate the prevalence of diabetes among Chinese adults...
  25. doi Biphasic insulin aspart 30 as insulin initiation or replacement therapy: the China cohort of the IMPROVE study
    Wenying Yang
    China Japan Friendship Hospital, Beijing, China
    Curr Med Res Opin 26:101-7. 2010
    ..To explore safety and efficacy of BIAsp 30 as initiation or replacement therapy in routine clinical practice in patients with poorly controlled diabetes in the Chinese cohort of the IMPROVE study...
  26. doi Percutaneous nephrolithotomy in infants: evaluation of a single-center experience
    Guohua Zeng
    Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, China
    Urology 80:408-11. 2012
    ..To evaluate the efficacy and safety of percutaneous nephrolithotomy (PCNL) in infants (<3 years) with renal calculi...