Yong zhen Zhang

Summary

Country: China

Publications

  1. doi request reprint Molecular diversity and phylogeny of Hantaan virus in Guizhou, China: evidence for Guizhou as a radiation center of the present Hantaan virus
    Yang Zou
    Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, 102206 Beijing, PR China
    J Gen Virol 89:1987-97. 2008
  2. pmc Human rabies in China
    Yong zhen Zhang
    Emerg Infect Dis 11:1983-4. 2005
  3. pmc Hantavirus infections in humans and animals, China
    Yong zhen Zhang
    State Key Laboratory for Infectious Disease Control and Prevention, Beijing, People s Republic of China
    Emerg Infect Dis 16:1195-203. 2010
  4. ncbi request reprint Hemorrhagic fever caused by a novel tick-borne Bunyavirus in Huaiyangshan, China
    Yong zhen Zhang
    State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Zhonghua Liu Xing Bing Xue Za Zhi 32:209-20. 2011
  5. pmc The ecology, genetic diversity, and phylogeny of Huaiyangshan virus in China
    Yong zhen Zhang
    State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China
    J Virol 86:2864-8. 2012
  6. doi request reprint Genetic diversity of Chinese rabies viruses: evidence for the presence of two distinct clades in China
    Yong zhen Zhang
    Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Infect Genet Evol 9:87-96. 2009
  7. ncbi request reprint Investigation of the role of healthy dogs as potential carriers of rabies virus
    Yong zhen Zhang
    Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Vector Borne Zoonotic Dis 8:313-9. 2008
  8. pmc Hantaviruses in rodents and humans, Inner Mongolia Autonomous Region, China
    Yong zhen Zhang
    Chinese Center for Disease Control and Prevention, Changping, Beijing, People s Republic of China
    Emerg Infect Dis 15:885-91. 2009
  9. ncbi request reprint [An epidemiologle investigation of hantaviruses carried by rodent hosts in Hunan province]
    Yong zhen Zhang
    National Institute of Communicable Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 102206, China
    Zhonghua Liu Xing Bing Xue Za Zhi 28:65-9. 2007
  10. pmc Seoul virus and hantavirus disease, Shenyang, People's Republic of China
    Yong zhen Zhang
    Chinese Center for Disease Control and Prevention, Beijing, People s Republic of China
    Emerg Infect Dis 15:200-6. 2009

Collaborators

Detail Information

Publications39

  1. doi request reprint Molecular diversity and phylogeny of Hantaan virus in Guizhou, China: evidence for Guizhou as a radiation center of the present Hantaan virus
    Yang Zou
    Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, 102206 Beijing, PR China
    J Gen Virol 89:1987-97. 2008
    ..Our results reveal that the highest genetic diversity of HTNV is in a limited geographical region of Guizhou, and suggest that Guizhou might be a radiation centre of the present form of HTNV...
  2. pmc Human rabies in China
    Yong zhen Zhang
    Emerg Infect Dis 11:1983-4. 2005
  3. pmc Hantavirus infections in humans and animals, China
    Yong zhen Zhang
    State Key Laboratory for Infectious Disease Control and Prevention, Beijing, People s Republic of China
    Emerg Infect Dis 16:1195-203. 2010
    ..Mortality rates also declined from the highest level of 14.2% in 1969 to ?1% during 1995-2007. However, the numbers of HFRS cases and deaths in China remain the highest in the world...
  4. ncbi request reprint Hemorrhagic fever caused by a novel tick-borne Bunyavirus in Huaiyangshan, China
    Yong zhen Zhang
    State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Zhonghua Liu Xing Bing Xue Za Zhi 32:209-20. 2011
    ..From April to July in 2009 and 2010, unexplained severe hemorrhagic fever-like illnesses occurred in farmers from the Huaiyangshan mountains range...
  5. pmc The ecology, genetic diversity, and phylogeny of Huaiyangshan virus in China
    Yong zhen Zhang
    State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China
    J Virol 86:2864-8. 2012
    ..HYSV RNA was found in human and both tick species, with greater prevalence in H. longicornis and lesser prevalence in R. microplus. Phylogenetic analyses indicate that HYSV is a novel species of the genus Phlebovirus...
  6. doi request reprint Genetic diversity of Chinese rabies viruses: evidence for the presence of two distinct clades in China
    Yong zhen Zhang
    Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Infect Genet Evol 9:87-96. 2009
    ..Our results also suggested that the Chinese RV isolates in clade I share a common recent ancestor with those circulating in southeast Asia...
  7. ncbi request reprint Investigation of the role of healthy dogs as potential carriers of rabies virus
    Yong zhen Zhang
    Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Vector Borne Zoonotic Dis 8:313-9. 2008
    ..These results do not provide support for the contention that healthy dogs act as carriers in rabies. Caution is urged when preliminary and nondefinitive tests, such as ELISA, are used to infer clinical status related to rabies...
  8. pmc Hantaviruses in rodents and humans, Inner Mongolia Autonomous Region, China
    Yong zhen Zhang
    Chinese Center for Disease Control and Prevention, Changping, Beijing, People s Republic of China
    Emerg Infect Dis 15:885-91. 2009
    ..Phylogenetic analysis of hantaviral genome sequences suggests that HFRS has been caused mainly by Hantaan virus in northeastern Inner Mongolia and by Seoul virus in central and western Inner Mongolia...
  9. ncbi request reprint [An epidemiologle investigation of hantaviruses carried by rodent hosts in Hunan province]
    Yong zhen Zhang
    National Institute of Communicable Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 102206, China
    Zhonghua Liu Xing Bing Xue Za Zhi 28:65-9. 2007
    ..To explore the hantavirus infection and their genotype in rodents in Hunan...
  10. pmc Seoul virus and hantavirus disease, Shenyang, People's Republic of China
    Yong zhen Zhang
    Chinese Center for Disease Control and Prevention, Beijing, People s Republic of China
    Emerg Infect Dis 15:200-6. 2009
    ..These results suggest that the HFRS outbreak in Shenyang was caused by SEOV that was circulating among local wild rats and had also infected the laboratory rats...
  11. ncbi request reprint Isolation and characterization of hantavirus carried by Apodemus peninsulae in Jilin, China
    Yong zhen Zhang
    Department of Hemorrhagic Fever, Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, Beijing 102206, China
    J Gen Virol 88:1295-301. 2007
    ..However, the viruses detected in A. peninsulae in China are genetically different from those detected in A. peninsulae in other countries. These data suggest that A. peninsulae is also a natural host for HTNV in north-eastern China...
  12. doi request reprint Isolation and genetic characterization of hantaviruses carried by Microtus voles in China
    Yang Zou
    Department of Hemorrhagic Fever, Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    J Med Virol 80:680-8. 2008
    ..maximowiczii is the natural host of KHAV including Yakeshi-Mm strains. Thus, in addition to Hantaan, Seoul, Dabieshan and Puumala-like Hokkaido viruses, at least two other hantaviruses, namely KHAV and VLAV, are circulating in China...
  13. pmc Ongoing spillover of Hantaan and Gou hantaviruses from rodents is associated with hemorrhagic fever with renal syndrome (HFRS) in China
    Wen Wang
    State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    PLoS Negl Trop Dis 7:e2484. 2013
    ....
  14. ncbi request reprint Molecular characterization of rabies virus isolates in China during 2004
    Yong zhen Zhang
    Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Virus Res 121:179-88. 2006
    ..Thus, our data suggest that rabies viruses currently circulating in China were similar, if not identical, to those reported in the previous epidemics...
  15. doi request reprint Genetic characterization of hantaviruses isolated from Guizhou, China: evidence for spillover and reassortment in nature
    Yang Zou
    Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, 102206, Beijing, China
    J Med Virol 80:1033-41. 2008
    ..Our results also suggest that HTNV from A. agrarius spilled over to R. norvegicus and natural reassortment between HTNV and SEOV occurred during or after the spillover...
  16. pmc Cross-species transmission in the speciation of the currently known murinae-associated hantaviruses
    Xian Dan Lin
    State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    J Virol 86:11171-82. 2012
    ..The detection of positive selection suggests that genetic drift may contribute to the speciation of Murinae-associated hantaviruses and that adaptation has a role as well...
  17. ncbi request reprint [Study on the epidemiological characteristics of hemorrhagic fever with renal syndrome in Inner Mongolia]
    Feng Xian Zhang
    National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
    Zhonghua Liu Xing Bing Xue Za Zhi 28:1101-4. 2007
    ..In order to better understand the epidemiological features of Hantviruses in Inner Mongolia...
  18. ncbi request reprint Detection of phylogenetically distinct Puumala-like viruses from red-grey vole Clethrionomys rufocanus in China
    Yong zhen Zhang
    Department of Hemorrhagic Fever, Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    J Med Virol 79:1208-18. 2007
    ..These results indicate that PUUV-like virus is present in China in addition to Hantaan, Seoul and Dabieshan viruses...
  19. pmc A tick-borne segmented RNA virus contains genome segments derived from unsegmented viral ancestors
    Xin Cheng Qin
    State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100206, China
    Proc Natl Acad Sci U S A 111:6744-9. 2014
    ..and experiences frequent host-switching and genomic reassortment. To our knowledge, JMTV is the first example of a segmented RNA virus with a genome derived in part from unsegmented viral ancestors...
  20. doi request reprint Dynamics of hantavirus infections in humans and animals in Wuhan city, Hubei, China
    Yan Jun Kang
    State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Changping Liuzi 5, 102206 Beijing, China
    Infect Genet Evol 12:1614-21. 2012
    ..Results of the present study showed that HFRS cases in Wuhan are caused by HTNV and SEOV. Phylogenetic analysis of the hantavirus sequences revealed that a novel genetic lineage of HTNV is present in rodents in Wuhan...
  21. pmc Migration of Norway rats resulted in the worldwide distribution of Seoul hantavirus today
    Xian Dan Lin
    State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    J Virol 86:972-81. 2012
    ..We hypothesize that an ancestor of phylogroup A SEOV variants was first exported from China to Europe and then spread through the New World following the migration of Norway rats...
  22. doi request reprint Genetic analysis of hantaviruses carried by reed voles Microtus fortis in China
    Yang Zou
    Department of Hemorrhagic Fever, Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Virus Res 137:122-8. 2008
    ..The newly characterized sequences from Yuanjiang might represent a novel distinct hantavirus species. Our results also demonstrated the great genetic diversity and complexity of the M. fortis-associated hantaviruses in China...
  23. ncbi request reprint [Analyses on the isolation and characterization of canine rabies virus isolates in Henan]
    Cheng long Xiong
    National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
    Zhonghua Liu Xing Bing Xue Za Zhi 28:261-7. 2007
    ..To analyze the genetic characteristics of two rabies virus isolates from Henan province and to compare their relations hip with known rabies virus isolates and vaccine strains...
  24. doi request reprint Molecular survey of hard ticks in endemic areas of tick-borne diseases in China
    Xin Lu
    State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, 102206 Beijing, China
    Ticks Tick Borne Dis 4:288-96. 2013
    ..Rapid and accurate identification and long-term monitoring of these ticks will be of significance to the prevention and control of tick-borne diseases in China...
  25. ncbi request reprint [The survey of 21 cases of human rabies in Anlong county in Guizhou province]
    Yong zhen Zhang
    Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
    Zhonghua Liu Xing Bing Xue Za Zhi 25:870-2. 2004
    ..To analyze 21 cases of rabies from February 8 to May 1 in 2004 in Anlong county in Guizhou province, and to explore the possible factors causing the epidemics...
  26. doi request reprint Pathogenicity of a natural reassortant hantavirus CGRn9415 in newborn rats and newborn mice
    Xiao Ping Chen
    State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Liuzi 5, 102206 Beijing, PR China
    J Gen Virol 93:1017-22. 2012
    ..These data suggest that the reassorted hantavirus behaves more like SEOV as far as the pathogenicity is concerned...
  27. doi request reprint Hemorrhagic fever caused by a novel Bunyavirus in China: pathogenesis and correlates of fatal outcome
    Yong zhen Zhang
    State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Clin Infect Dis 54:527-33. 2012
    ....
  28. ncbi request reprint [The epidemic characteristics and preventive measures of hemorrhagic fever with syndromes in China]
    Yong zhen Zhang
    Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
    Zhonghua Liu Xing Bing Xue Za Zhi 25:466-9. 2004
    ..To summarize and analyze the epidemic situation of hantaviruses including geographic distribution, types and prevalent intensity of epidemic areas of hantavirus for the last 30 years in China, and to discuss relative preventive measures...
  29. doi request reprint A new subtype of Thottapalayam virus carried by the Asian house shrew (Suncus murinus) in China
    Wen Ping Guo
    State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, 102206 Beijing, China
    Infect Genet Evol 11:1862-7. 2011
    ..Phylogenetic analysis revealed that the new variants formed a distinct lineage within TPMV...
  30. ncbi request reprint [The epidemic situation of human rabies from 1984 to 2002 and its preventive measures in China]
    Yong zhen Zhang
    Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
    Zhonghua Liu Xing Bing Xue Za Zhi 24:883-8. 2003
    ..To summarize and analyze the epidemic situation of human rabies from 1984 to 2002 in China, and to explore the possible factors causing the increase of cases so as to provide evidence for preventive and control measures...
  31. ncbi request reprint [Identification of Haemaphysalis longicornis and Rhipicephalus microplus]
    Xin Cheng Qin
    National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Zhonghua Liu Xing Bing Xue Za Zhi 32:608-12. 2011
    ..To establish a method combined morphology and molecular marker for identifying Haemaphysalis longicornis and Rhipicephalus microplus...
  32. doi request reprint Infection and pathogenesis of Huaiyangshan virus (a novel tick-borne bunyavirus) in laboratory rodents
    Xiao Ping Chen
    State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, 102206 Beijing, PR China
    J Gen Virol 93:1288-93. 2012
    ..Our data demonstrate that HYSV can cause a lethal infection of both newborn mice and newborn rats with apparent pathological damage of the liver. This animal model may help to understand the pathogenesis of the HYSV infection in humans...
  33. pmc Phylogeny and origins of hantaviruses harbored by bats, insectivores, and rodents
    Wen Ping Guo
    State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China
    PLoS Pathog 9:e1003159. 2013
    ..Overall, these data indicate that bats are likely to be important natural reservoir hosts of hantaviruses...
  34. ncbi request reprint [The study for the immuno-protection of E. coli O157:H7 outer membrane protein]
    Yan Zhang
    Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
    Zhonghua Yi Xue Za Zhi 84:58-62. 2004
    ..To evaluate the protective efficacy against a lethal dose of E. coli O157:H7 after intranasal, oral and subcutaneous immunization with the outer membrane protein (OMP) extracted from the whole cell of E. coli O157:H7...
  35. ncbi request reprint [Genetic characteristics of hantaviruses carried by Microtus maximowixzii in Yakeshi of Inner Mongolia, China]
    Mei Li Cong
    College of Animal Science, Shihezi University, Shihezi 832003, China
    Zhonghua Liu Xing Bing Xue Za Zhi 33:832-5. 2012
    ....
  36. pmc Co-circulation of multiple hemorrhagic fever diseases with distinct clinical characteristics in Dandong, China
    Zhi hai Chen
    Department of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China
    PLoS ONE 9:e89896. 2014
    ..Overall, our data reveal the complexity of pathogens causing HFs in a single Chinese hospital, and highlight the need for accurate early diagnosis and a better understanding of their distinctive clinical features. ..
  37. ncbi request reprint [Cloning and expression of the nucleoprotein gene of Puumala-like virus]
    Wen rong Yao
    National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
    Zhonghua Liu Xing Bing Xue Za Zhi 30:171-4. 2009
    ..In order to detect Hokkaido virus (HOKV), a recombinant baculovirus containing the nucleoprotein (NP) gene of HOKV was constructed, and then the NP was expressed in insect cell...
  38. ncbi request reprint [SIRT1 inhibits IL-1β mRNA transcription in lipopolysaccharide tolerant THP-1 cells]
    Xiao Ping Chen
    National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Zhonghua Liu Xing Bing Xue Za Zhi 32:613-6. 2011
    ..To explore the role of silent information regulation 2 homolog 1 (SIRT1) in the regulation of IL-1β mRNA transcription in lipopolysaccharide (LPS) tolerant THP-1 cells...
  39. ncbi request reprint [An epidemiological study of rabies virus in domestic dogs, cats and wildlife and the immunogenicity study for rabies vaccines derived from different cell cultured virus strains]
    Guan mu Dong
    National Institute for the Control of Parmaceutical and Biological Products, Beijing 100050, China
    Bing Du Xue Bao 23:417-23. 2007
    ..1%-47.9% and 100% respectively, and there was no moderate or severe adverse reactions observed. These data showed the vaccines have satisfactory effect on safety and protection...