Yan Zhang

Summary

Country: China

Publications

  1. ncbi request reprint Multipotent stem cells from the young rat inner ear
    Xiangxin Lou
    School of Life Science, East China Normal University, Shanghai, PR China
    Neurosci Lett 416:28-33. 2007
  2. doi request reprint Alteration of vitamin D metabolic enzyme expression and calcium transporter abundance in kidney involved in type 1 diabetes-induced bone loss
    Y Zhang
    Center of System Biomedical Sciences, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, People s Republic of China
    Osteoporos Int 22:1781-8. 2011
  3. ncbi request reprint Short- to mid-term effects of ovariectomy on bone turnover, bone mass and bone strength in rats
    Yan Zhang
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China
    Biol Pharm Bull 30:898-903. 2007
  4. doi request reprint Changes of renal vitamin D metabolic enzyme expression and calcium transporter abundance in obstructive nephropathy
    Yan Zhang
    Center of System Biomedical Sciences, University of Shanghai for Science and Technology, Shanghai, China
    Nephrology (Carlton) 16:710-4. 2011
  5. ncbi request reprint [Effect of Erythrina variegata on Ca2+ homeostasis in ovariectomized rats and action mechanism]
    Yan Zhang
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Shenzhen 518057, China
    Zhongguo Zhong Yao Za Zhi 32:627-30. 2007
  6. ncbi request reprint Anti-osteoporotic effect of Erythrina variegata L. in ovariectomized rats
    Yan Zhang
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, PR China
    J Ethnopharmacol 109:165-9. 2007
  7. doi request reprint Early molecular responses of bone to obstructive nephropathy induced by unilateral ureteral obstruction in mice
    Sa Sa Gu
    Center for Systems Biomedical Sciences, University of Shanghai for Science and Technology, Shanghai, China
    Nephrology (Carlton) 17:767-73. 2012
  8. doi request reprint Erythrina variegata extract exerts osteoprotective effects by suppression of the process of bone resorption
    Yan Zhang
    Centre of System Biomedical Sciences, University of Shanghai for Science and Technology, Shanghai 200093, People s Republic of China
    Br J Nutr 104:965-71. 2010
  9. ncbi request reprint Ovariectomy worsens secondary hyperparathyroidism in mature rats during low-Ca diet
    Yan Zhang
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Shenzhen, Hong Kong, China
    Am J Physiol Endocrinol Metab 292:E723-31. 2007
  10. ncbi request reprint Downregulation of CD4+CD25+ regulatory T cells may underlie enhanced Th1 immunity caused by immunization with activated autologous T cells
    Qi Cao
    Department of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Cell Res 17:627-37. 2007

Collaborators

Detail Information

Publications145 found, 100 shown here

  1. ncbi request reprint Multipotent stem cells from the young rat inner ear
    Xiangxin Lou
    School of Life Science, East China Normal University, Shanghai, PR China
    Neurosci Lett 416:28-33. 2007
    ..This work raises the possibility that inner ear cells in the early post-natal rat have the character of pluripotent stem cells and might be a source for cell replacement therapy in the inner ear...
  2. doi request reprint Alteration of vitamin D metabolic enzyme expression and calcium transporter abundance in kidney involved in type 1 diabetes-induced bone loss
    Y Zhang
    Center of System Biomedical Sciences, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, People s Republic of China
    Osteoporos Int 22:1781-8. 2011
    ..The results revealed the alteration of vitamin D metabolic enzyme expression and the downregulation of renal calcium transporter abundance in type 1 diabetic mice...
  3. ncbi request reprint Short- to mid-term effects of ovariectomy on bone turnover, bone mass and bone strength in rats
    Yan Zhang
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China
    Biol Pharm Bull 30:898-903. 2007
    ....
  4. doi request reprint Changes of renal vitamin D metabolic enzyme expression and calcium transporter abundance in obstructive nephropathy
    Yan Zhang
    Center of System Biomedical Sciences, University of Shanghai for Science and Technology, Shanghai, China
    Nephrology (Carlton) 16:710-4. 2011
    ....
  5. ncbi request reprint [Effect of Erythrina variegata on Ca2+ homeostasis in ovariectomized rats and action mechanism]
    Yan Zhang
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Shenzhen 518057, China
    Zhongguo Zhong Yao Za Zhi 32:627-30. 2007
    ..To study the effect of Erythrina variegata (EV) on Ca2+ homeostasis in ovariectomized rats and the regulation on gene expression in duodenum and kidney...
  6. ncbi request reprint Anti-osteoporotic effect of Erythrina variegata L. in ovariectomized rats
    Yan Zhang
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, PR China
    J Ethnopharmacol 109:165-9. 2007
    ..Thus, the present study clearly demonstrated that EV could suppress the high rate of bone turnover induced by estrogen deficiency, inhibit bone loss and improve the biomechanical properties of bone in the OVX rats...
  7. doi request reprint Early molecular responses of bone to obstructive nephropathy induced by unilateral ureteral obstruction in mice
    Sa Sa Gu
    Center for Systems Biomedical Sciences, University of Shanghai for Science and Technology, Shanghai, China
    Nephrology (Carlton) 17:767-73. 2012
    ..This study was performed to address the bone injury and the early molecular responses of bone to obstructive nephropathy induced by unilateral ureteral obstruction in mice...
  8. doi request reprint Erythrina variegata extract exerts osteoprotective effects by suppression of the process of bone resorption
    Yan Zhang
    Centre of System Biomedical Sciences, University of Shanghai for Science and Technology, Shanghai 200093, People s Republic of China
    Br J Nutr 104:965-71. 2010
    ....
  9. ncbi request reprint Ovariectomy worsens secondary hyperparathyroidism in mature rats during low-Ca diet
    Yan Zhang
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Shenzhen, Hong Kong, China
    Am J Physiol Endocrinol Metab 292:E723-31. 2007
    ..These results suggest that estrogen is necessary for the full adaptive response to LCD mediated by both PTH and 1,25(OH)2D3...
  10. ncbi request reprint Downregulation of CD4+CD25+ regulatory T cells may underlie enhanced Th1 immunity caused by immunization with activated autologous T cells
    Qi Cao
    Department of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Cell Res 17:627-37. 2007
    ..We suggest that dampened Treg function likely contributes to enhanced Th1 response in immunized mice and is at least part of the mechanism underlying the boosted anti-tumor immunity...
  11. doi request reprint Role of GADD45 beta in the regulation of synovial fluid T cell apoptosis in rheumatoid arthritis
    Fang Du
    Shanghai Institute of Immunology, Institute of Medical Sciences, Jiao Tong University School of Medicine, Shanghai, China
    Clin Immunol 128:238-47. 2008
    ..Taken together, our results suggest a novel mechanism by which specific cytokines in the RA SF elevate GADD45 beta expression in local Th1 cells and subsequently leading to the enhanced T cell survival...
  12. doi request reprint Fructus ligustri lucidi extract improves calcium balance and modulates the calciotropic hormone level and vitamin D-dependent gene expression in aged ovariectomized rats
    Yan Zhang
    Shenzhen Research Institute, The Hong Kong Polytechnic University, State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Shenzhen, People s Republic of China
    Menopause 15:558-65. 2008
    ..In the present study, we aimed to determine whether FLL could regulate calcium balance in aged OVX rats and to study the potential mechanisms that mediate its action in vivo...
  13. doi request reprint Thiolated Eudragit nanoparticles for oral insulin delivery: preparation, characterization and in vivo evaluation
    Yan Zhang
    Department of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, 110016, China
    Int J Pharm 436:341-50. 2012
    ..33±0.33%, an increase of 2.8-fold compared with Eul NPs (2.65±0.63%). This delivery system is a promising novel tool to improve the absorption of protein and peptide drugs in the intestinal tract...
  14. ncbi request reprint Involvement of the skeletal renin-angiotensin system in age-related osteoporosis of ageing mice
    Sa Sa Gu
    Center for Systems Biomedical Science, University of Shanghai for Science and Technology, Shanghai, PR China
    Biosci Biotechnol Biochem 76:1367-71. 2012
    ..The enhancement of renin and AGT expression in the bone tissue resulted in the increased production of angiotensin II which plays an important role in the pathology of age-related osteoporosis...
  15. pmc OTUB1 overexpression in mesangial cells is a novel regulator in the pathogenesis of glomerulonephritis through the decrease of DCN level
    Yan Zhang
    Key Laboratory of Molecular Medicine of Chinese Education Ministry, Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, People s Republic of China
    PLoS ONE 7:e29654. 2012
    ..The aim of this study is to investigate the role of OTUB1 expression in MC and its relationship with DCN during glomerulonephritis...
  16. doi request reprint Modulation of TSC-mTOR signaling on immune cells in immunity and autoimmunity
    Hui Yang
    Department of Immunology, Shanghai Medical College, Fudan University, Shanghai, China
    J Cell Physiol 229:17-26. 2014
    ..Furthermore, we focus on the role of TSC1/2-mTOR signaling pathway in immune cell mediated diseases, especially autoimmunity...
  17. ncbi request reprint Effects of Fructus Ligustri Lucidi extract on bone turnover and calcium balance in ovariectomized rats
    Yan Zhang
    Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, China
    Biol Pharm Bull 29:291-6. 2006
    ..05, vs. OVX). Our study is the first to report that FLL can modulate bone turnover and calcium balance in OVX rats and it might be a potential candidate for prevention and treatment of postmenopausal osteoporosis...
  18. doi request reprint A critical role of Cyr61 in interleukin-17-dependent proliferation of fibroblast-like synoviocytes in rheumatoid arthritis
    Qiuyu Zhang
    Shanghai Jiao Tong University School of Medicine, and Guanghua Rheumatology Hospital, Shanghai, China
    Arthritis Rheum 60:3602-12. 2009
    ..However, the role that Cyr61 plays in FLS proliferation has remained undetermined. The aim of this study was to identify the role of Cyr61 in regulating the proliferation of FLS derived from patients with RA...
  19. ncbi request reprint Effects of eleven flavonoids from the osteoprotective fraction of Drynaria fortunei (KUNZE) J. SM. on osteoblastic proliferation using an osteoblast-like cell line
    Xin Luan Wang
    School of Chinese Materia Medica, Shenyang Pharmaceutical University, People s Republic of China
    Chem Pharm Bull (Tokyo) 56:46-51. 2008
    ..The main peaks in the HPLC fingerprint of the active fraction (DFB) were also identified...
  20. pmc Trabecular bone deterioration at the greater trochanter of mice with unilateral obstructive nephropathy
    Sa Sa Gu
    Center for Systems Biomedical Sciences, University of Shanghai for Science and Technology, Shanghai 200093, China
    Asian J Androl 15:564-6. 2013
    ..01) and bone surface/bone volume (P<0.05) in UUO mice. The present study demonstrates that UUO-induced unilateral obstructive nephropathy has markedly detrimental effects on the trabecular trochanter of the femur. ..
  21. pmc Salinomycin inhibits proliferation and induces apoptosis of human hepatocellular carcinoma cells in vitro and in vivo
    Fan Wang
    Department of Gastroenterology, Shanghai Tenth People s Hospital, Tongji University of Medicine, Shanghai, People s Republic of China
    PLoS ONE 7:e50638. 2012
    ..This study demonstrates Sal inhibits proliferation and induces apoptosis of HCC cells in vitro and in vivo and one potential mechanism is inhibition of Wnt/β-catenin signaling via increased intracellular Ca(2+) levels...
  22. doi request reprint Effects of different elicitors on yield of tropane alkaloids in hairy roots of Anisodus acutangulus
    Guoyin Kai
    Laboratory of Plant Biotechnology, College of Life and Environment Sciences, Shanghai Normal University, Shanghai 200234, People s Republic of China
    Mol Biol Rep 39:1721-9. 2012
    ..Our results showed that hairy root culture of A. acutangulus in combination with elicitors was a promising way for production of tropane alkaloids in the future...
  23. pmc Co-expression of AaPMT and AaTRI effectively enhances the yields of tropane alkaloids in Anisodus acutangulus hairy roots
    Guoyin Kai
    Laboratory of Plant Biotechnology, College of Life and Environment Sciences, Shanghai, Normal University, Shanghai 200234, China
    BMC Biotechnol 11:43. 2011
    ..acutangulus), which is a Solanaceous perennial plant that is endemic to China and is an attractive resource plant for production of TA...
  24. pmc Exploring the influence of carbon nanoparticles on the formation of β-sheet-rich oligomers of IAPP₂₂₋₂₈ peptide by molecular dynamics simulation
    Jingjing Guo
    School of Pharmacy, Lanzhou University, Lanzhou, China
    PLoS ONE 8:e65579. 2013
    ..Our study can not only enhance the understanding about potential effects of nanomaterials to amyloid formation, but also provide valuable information to develop potential β-sheet formation inhibitors against type II diabetes...
  25. pmc Neutralisation of peritoneal IL-17A markedly improves the prognosis of severe septic mice by decreasing neutrophil infiltration and proinflammatory cytokines
    Jinbao Li
    Department of Anesthesiology, Changhai Hospital, Second Military Medical University, Shanghai, China
    PLoS ONE 7:e46506. 2012
    ..The main source of peritoneal fluid IL-17A in septic mice was identified...
  26. pmc Matrine induces apoptosis in human acute myeloid leukemia cells via the mitochondrial pathway and Akt inactivation
    Shenghui Zhang
    Key Laboratory of Molecular Medicine, Ministry of Education, and Department of Biochemistry and Molecular Biology, Fudan University Shanghai Medical College, Shanghai, China
    PLoS ONE 7:e46853. 2012
    ..These findings indicate that matrine can inhibit cell proliferation and induce apoptosis of AML cells and may be a novel effective candidate as chemotherapeutic agent against AML...
  27. doi request reprint Enhanced cartilage formation by inhibiting cathepsin K expression in chondrocytes expanded in vitro
    Yan Zhang
    Department of Plastic and Reconstructive Surgery, National Tissue Engineering Center of China, Shanghai 9th People s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Biomaterials 33:7394-404. 2012
    ....
  28. doi request reprint Cytotoxic triterpene saponins from the leaves of Aralia elata
    Yan Zhang
    Key Laboratory of Structure Based Drug Design and Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, People s Republic of China
    Fitoterapia 83:806-11. 2012
    ..99μM and 7.93μM respectively. In addition, compounds 5 and 6 showed significant cytotoxic activity against HL60 cancer cells with IC(50) values of 5.75μM and 7.51μM, respectively...
  29. pmc Tumor-specific expression of microRNA-26a suppresses human hepatocellular carcinoma growth via cyclin-dependent and -independent pathways
    Lizao Chen
    Clinical Research Centre, Changhai Hospital, Second Military Medical University, Shanghai, China
    Mol Ther 19:1521-8. 2011
    ..Moreover, hAFP-TERT dual promoter-mediated miR-26a expression could specifically exert potential antitumor activity and provide a novel targeting approach for cancer therapy...
  30. doi request reprint Responses of soil bacteria to long-term and short-term cadmium stress as revealed by microbial community analysis
    Yan Zhang
    Key Laboratory of Terrestrial Ecological Process, Institute of Applied Ecology, Chinese Academy of Science, Shenyang, People s Republic of China
    Bull Environ Contam Toxicol 82:367-72. 2009
    ..In contrast, severe cadmium stress likely presented a condition that fewer microbial populations could survive, thus leading to reduced microbial genetic diversity...
  31. ncbi request reprint [Effects of superoxide dismutase on the periapical periodontitis in rat]
    Qingshan Wang
    Department of Endodontics, Attached Hospital, Binzhou Medical College, Binzhou 256603, China
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 27:1066-9. 2010
    ..01). The results showed that SOD could control periapical inflammation and induce the proliferation of dentin and cementum. Therefore, SOD might be an ideal biocompatible material for root canal therapy...
  32. ncbi request reprint [Clinical characteristics of fat replacement of left ventricular myocardium]
    Chao wu Yan
    Department of Radiology, Chinese Academy of Medical Sciences, Beijing 100037, China
    Zhonghua Xin Xue Guan Bing Za Zhi 39:152-5. 2011
    ..To evaluate the clinical characteristics of left ventricular fat replacement...
  33. ncbi request reprint [Transrectal real-time tissue elastography combined with grey-scale ultrasound: valuable for the diagnosis of prostate peripheral zone lesions]
    Yan Zhang
    Department of Ultrasound, General Hospital of Chinese PLA, Beijing 100853, China
    Zhonghua Nan Ke Xue 16:979-83. 2010
    ..To investigate the value of strain patterns by transrectal real-time tissue elastography (TRTE) combined with transrectal ultrasonography (TRUS) in the differential diagnosis of the peripheral zone lesions of the prostate...
  34. doi request reprint QTL analysis for yield components and kernel-related traits in maize across multi-environments
    Bo Peng
    Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing, 100081, China
    Theor Appl Genet 122:1305-20. 2011
    ..Moreover, QTL on chr. 1, chr. 4, and chr. 9 were detected in both populations. These chromosomal regions could be targets for marker-assisted selection, fine mapping, and map-based cloning in maize...
  35. pmc QDMR: a quantitative method for identification of differentially methylated regions by entropy
    Yan Zhang
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China
    Nucleic Acids Res 39:e58. 2011
    ..This approach provides an effective tool for the high-throughput identification of potential functional regions involved in epigenetic regulation...
  36. ncbi request reprint Saltwater intrusion in the Laizhou Gulf, Shandong Province, China: causes and its impact on coastal areas
    Shanzhong Qi
    College of Population, Resources and Environment, Shandong Normal University, Jinan, People s Republic of China
    Ambio 36:361-2. 2007
  37. ncbi request reprint [Registration technology for mandibular angle osteotomy based on augmented reality]
    Ming Zhu
    Department of Plastic and Reconstructive Surgery, Ninth People s Hospital, Shanghai Jiao Tong University School of Medicine Shanghai 200011, China
    Shanghai Kou Qiang Yi Xue 19:571-4. 2010
    ..To establish an effective path to register the operative plan to the real model of mandible made by rapid prototyping (RP) technology...
  38. ncbi request reprint Phospholipids-based microbubbles sonoporation pore size and reseal of cell membrane cultured in vitro
    Ying Zheng Zhao
    Department of Clinical Pharmacology, General Hospital of Beijing Military Command of PLA, Dong Si Shi Tiao Road, Dongcheng District, Beijing, People s Republic of China
    J Drug Target 16:18-25. 2008
    ..To investigate phospholipids-based microbubbles induced sonoporation and cell membrane reseal in vitro under various conditions...
  39. ncbi request reprint [Effect of Alternanthera philoxeroides on enzymic histochemistry of Oncomelania hupensis]
    Ping Tan
    Department of Parasitology, Medical College of Wuhan Science and Technical University, Wuhan 430065, China
    Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 27:11-6. 2009
    ..To investigate the mechanisms of Alternanthera philoxeroides (Mardus) Grisebach in inhibiting Oncomelania snails' locomotivity and killing effect...
  40. ncbi request reprint [Extraction process and content determination of total organic acids from Pothos chinensis]
    Wen qing Yin
    Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Ministry of Education of China, College of Chemistry and Chemical Engineering, Guangxi Normal University, Guilin 541004, China
    Zhong Yao Cai 32:124-6. 2009
    ..To study the optimum extracting process of total organic acids from Pothos chinensis and establish a determination method for total organic acids...
  41. pmc Reduced expression of cenp-e in human hepatocellular carcinoma
    Zijie Liu
    The Key Laboratory of Laboratory Medical Diagnostics, ministry of education the faculty of laboratory medicine, Chongqing Medical University, Chongqing PR China
    J Exp Clin Cancer Res 28:156. 2009
    ..We investigate the expression of CENP-E in human hepatocellular carcinoma,. and analyze the effect of low CENP-E expression on chromosome separation in normal liver cell line (LO2)...
  42. ncbi request reprint [A pilot study of three dimensional printing of human bone marrow stem cells (hBMSCs)]
    Gang Chai
    Department of Plastic and Reconstructive Surgery, Ninth People s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Tissue Engineering Shanghai 200011, China
    Shanghai Kou Qiang Yi Xue 19:77-80. 2010
    ..To establish a three-dimensional biological printing technique of hBMSCs...
  43. doi request reprint Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine
    Tao Deng
    Department of Gastroenterology, Renmin Hospital of Wuhan University, No 238 Jiefang Road, Wuhan, Hubei 430064, China
    Life Sci 84:311-20. 2009
    ..In our model, we aimed to explore the cytotoxicity of 5-Aza-2'-deoxycytidine (5-Aza-CdR) against the colorectal cell line, Lovo, and further characterize the possible mechanisms...
  44. doi request reprint HSP70 protects intestinal epithelial cells from hypoxia/reoxygenation injury via a mechanism that involves the mitochondrial pathways
    Zhi Qiang Yuan
    Institute of Burn Research, Southwest Hospital, State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University, Chongqing, China
    Eur J Pharmacol 643:282-8. 2010
    ....
  45. pmc The prediction of protein-protein interaction networks in rice blast fungus
    Fei He
    State Key Laboratory for ArgoBiotechnology, College of Biological Sciences, China Agricultural University, Beijing 100193, PR China
    BMC Genomics 9:519. 2008
    ..Inspired by recent advances in PPI prediction, we constructed a PPI map of this important fungus...
  46. doi request reprint Construction and characterization of the HMGB1 mutant as a competitive antagonist to HMGB1 induced cytokines release
    Zhiqiang Yuan
    Institute of Burn Research, Southwest Hospital, State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University, 30 Gaotanyan Street, Chongqing 400038, China
    Biochem Biophys Res Commun 372:703-7. 2008
    ..This may be of significant importance in providing a new anti-inflammatory strategy for the treatment of severe sepsis and other inflammatory disorders...
  47. ncbi request reprint [Helicobacter pylori VacA up-regulates secretion of macrophages by transfection of VacA eukaryotic expression vector]
    Cunyan Li
    Institute of Pathogenic Biology, University of South China, Hengyang 421001, China
    Wei Sheng Wu Xue Bao 48:349-54. 2008
    ..The over-expression of VacA fusion protein can up-regulate secretion of macrophages. Activation of NF-kappaB is probably involved in VacA induced cytokines production...
  48. ncbi request reprint [Effects on the survival of rat's abdominal axial skin flap after the combination of VEGF gene therapy and skin flap delay]
    Yan Zhang
    Department of Orthopedic Traumatology, Shandong Provincial Hospital, Jinan, China
    Zhonghua Zheng Xing Wai Ke Za Zhi 24:39-41. 2008
    ..To investigate the effect of VEGF (vascular endothelial growth factor) gene therapy and skin flap delay on the survival of rat's abdominal axial skin flap...
  49. ncbi request reprint Effect of methamidophos on soil fungi community in microcosms by plate count, DGGE and clone library analysis
    Xinyu Li
    Microbial Resources and Ecology Group Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China
    J Environ Sci (China) 20:619-25. 2008
    ..Clone sequencing analysis indicated the stimulation of pathogenic and unculturable fungal populations by methamidophos treatment, suggetsing potential risks of plant disease outbreak...
  50. doi request reprint Probiotic yogurt effects on intestinal flora of patients with chronic liver disease
    Jun E Liu
    School of Nursing, Capital Medical University, Beijing, China
    Nurs Res 59:426-32. 2010
    ..Patients with chronic liver disease generally have intestinal flora imbalance that is related to the development and worsening of the disease...
  51. ncbi request reprint [Investigation of clinical pathology and treatments on the auricle pseudocyst]
    Xiao Tong Zhang
    Department of Otorhinolaryngology Head and Neck Surgery, Xi an Jiaotong University, Shaanxi 710004, China
    Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 45:640-4. 2010
    ..To study the clinical pathology and treatments on the pseudocyst of auricle...
  52. ncbi request reprint [The change rules and correlation between specific leaf weight and dry weight of rhizoma of Atractylodes macrocephala]
    Yan Bai
    School of Forestry and Biotechnology, Zhejiang Forestry University, Lin an 311300, China
    Zhong Yao Cai 32:1013-6. 2009
    ..To study the change rules of specific leaf weight, dry weight of rhizoma and the drying rate of annual and biennial Atractylodes macrocephala...
  53. ncbi request reprint [Transient analgesic effect of electroacupuncture at Taiyang (EX-HN 5) for treatment of migraine with hyperactivity of the liver-yang]
    Jian Wei Zhou
    Institute of Acupuncture and Meridians, Sichuan Provincial Academy of TCM, Chengdu 610031, China
    Zhongguo Zhen Jiu 27:159-63. 2007
    ..To explore the difference of therapeutic effects between electroacupuncture (EA) and medication for treatment of migraine with hyperactivity of the liver-yang...
  54. ncbi request reprint [Effect of chronic enhanced external counterpulsation on arterial endothelial cells of porcine with hypercholesteremia]
    Xiao Lin Chen
    Department of Cardiology, First Affiliated Hospital, Sun Yat Sen University, Guangzhou 510089, China
    Di Yi Jun Yi Da Xue Xue Bao 25:1491-3. 2005
    ..To verify whether chronic enhanced external counterpulsation (EECP) may repair artery endothelial cells (ECs) damage resulted from hypercholesteremia in pigs...
  55. ncbi request reprint [Clinical observation on Ashi points Sihua needling method for treatment of acute soft tissue injury]
    Jian Wei Zhou
    Institute of Acupuncture and Meridians, Sichuan Provincial Academy of TCM, Chengdu 610031, China
    Zhongguo Zhen Jiu 25:753-6. 2005
    ..To observe therapeutic effect of Ashi points Sihua needling method for treatment of acute soft tissue injury...
  56. ncbi request reprint Characteristics and prognostic factors of acute myeloid leukemia with t (8; 21) (q22; q22)
    Yue yun Lai
    Peking University Institute of Hematology, People s Hospital, Beijing 100044, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 13:733-40. 2005
    ..HSCT should be recommended to t (8; 21) AML in China, especially to those with adverse prognostic factors...
  57. doi request reprint 5-Aza-2'-deoxycytidine reactivates expression of RUNX3 by deletion of DNA methyltransferases leading to caspase independent apoptosis in colorectal cancer Lovo cells
    Tao Deng
    Department of Internal Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei 430064, China
    Biomed Pharmacother 63:492-500. 2009
    ..We therefore conclude that RUNX3 is a relevant target for methyltransferases dependent effects of 5-Aza-CdR on colorectal cancer Lovo cells...
  58. ncbi request reprint Development of two enzyme-linked immunosorbent assays for detection of endosulfan residues in agricultural products
    Shuo Wang
    Tianjin Key Laboratory of Food Nutrition and Safety, Faculty of Food Engineering and Biotechnolgy, Tianjin University of Science and Technology, People s Republic of China
    J Agric Food Chem 53:7377-84. 2005
    ..93). The developed immunoassay methods are the suitable methods for the rapid quantitative and reliable determination of endosulfan residues in agricultural products...
  59. ncbi request reprint [About mnemonics of English translated TCM terms produced from morpheme-level translation]
    Yan Zhang
    English Department, Shaanxi College of Traditional Chinese Medicine, Xianyang
    Zhongguo Zhong Xi Yi Jie He Za Zhi 25:562-4. 2005
    ....
  60. ncbi request reprint [Experimental study of the effect of rhTNF-alpha on human sperm mitochondrial function and motility in vitro]
    Jiang Bian
    Research Institute of Andrology, Medical College, Three Gorges University, Yichang, Hubei 443003, China
    Zhonghua Nan Ke Xue 10:415-9. 2004
    ..To study the effect of rhTNF-alpha on human sperm mitochondrial function and motility in vitro...
  61. ncbi request reprint [Studies on evaluation of brain death]
    Ying Ying Su
    Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, China
    Zhonghua Nei Ke Za Zhi 43:250-3. 2004
    ..To investigate the methods of evaluating brain death accurately and objectively...
  62. ncbi request reprint [Pharyagoesophageal sphinoter myotomy for voice rehabilitation after total laryngectomy]
    Ping Jiang Ge
    Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100005, China
    Zhonghua Er Bi Yan Hou Ke Za Zhi 38:12-4. 2003
    ..To reduce the effect of pharyngoesophageal sphincter on the Blom-Singer prosthesis voice restoration following total laryngectomy, the pharyagoesphageal sphincter myotomy was designed and carried out...
  63. ncbi request reprint [Effects of probiotics additives EM on growth metabolism and immune function of blue fox in growth phase]
    Xinhong Li
    College of Agriculture and Biology, Shanghai Jiaotong University, Shanghai 201101
    Ying Yong Sheng Tai Xue Bao 13:1429-32. 2002
    ..EM, which a kind of efficient, safe and environmental protection additives, can be extended and applied in farming of fur animals...
  64. ncbi request reprint [A quantitative assay for telomerase activity in peripheral blood mononuclear cells from patients with acute leukemia]
    Li Ping Ma
    People s Hospital of Peking University, Beijing 100044, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 10:191-4. 2002
    ..In conclusion, the met hod is rapid, simple and quantitative, the telomerase activities of PBMNCs from acute leukemia patients are significantly higher than that of the normal controls...
  65. ncbi request reprint Impacts of ascorbic acid and thiamine supplementation at different concentrations on lead toxicity in testis
    Chunhong Wang
    Department of Toxicology, School of Public Health, Wuhan University, Donghu Road 115, Wuhan 430071, P R China
    Clin Chim Acta 370:82-8. 2006
    ..We explored the mechanism and examine the impacts of combined administration of ascorbic acid and thiamine at different levels on apoptosis in the testes of lead-exposed mice...
  66. ncbi request reprint [Multicenter randomized controlled study on acupuncture-massage comprehensive program for treatment of cervical spondylosis of arterial type]
    Jian Wei Zhou
    Institute of Acupuncture and Meridians, Sichuan Provincial Academy of TCM, Chengdu, China
    Zhongguo Zhen Jiu 25:227-31. 2005
    ..To probe into clinical value of the acupuncture-massage comprehensive program for treatment of cervical spondylosis of arterial type (CSA)...
  67. ncbi request reprint Docetaxel influences autocrine of transforming growth factors and induces apoptosis in human ovarian cancer cell line AO
    Yan Zhang
    Department of Gynecology, The First Clinical College, Nanjing University of Traditional Chinese Medicine, Nanjing 210029
    Chin Med Sci J 21:204. 2006
  68. ncbi request reprint [Evaluating comprehensive quality of sediment in Dianchi Lake using adjusted AHP method and 137Cs dating]
    Yan Zhang
    Department of Urban and Resources Science, Nanjing University, Nanjing 210093, China
    Huan Jing Ke Xue 27:1531-6. 2006
    ....
  69. ncbi request reprint Comparing transfection efficiency and safety for antisense oligodeoxyribonucleotide between phospholipids-based microbubbles and liposomes
    Ying Zheng Zhao
    Department of Clinical Pharmacology, General Hospital of Beijing Command of PLA, Beijing 100700, People s Republic of China
    J Drug Target 14:687-93. 2006
    ..To compare transfection efficiency and safety for antisense oligodeoxynucleotides (AS-ODNs) between two type of phospholipids-based vectors...
  70. ncbi request reprint [Comparison of sonoporation effect of liposomes and phospholipids-based microbubbles on cultured cell membrane]
    Ying Zheng Zhao
    Department of Clinical Pharmacology, General Hospital of Beijing Command, PLA, Beijing 100700, China
    Yao Xue Xue Bao 41:1176-9. 2006
    ..To compare sonoporation effect of two phospholipids-based vectors-liposomes and microbubbles on cultured cell membrane...
  71. ncbi request reprint [Establishment of a pig model of chronic ally enhanced external counterpulsation]
    Xiao Lin Chen
    Department of Cardiology, First Affiliated Hospital, Sun Yat Sen University, Guangzhou 510089, China
    Nan Fang Yi Ke Da Xue Xue Bao 26:613-4. 2006
    ..To establish a pig model of chronic external counterpulsation...
  72. ncbi request reprint Regulation of melanocyte apoptosis by Stathmin 1 expression
    Yan Zhang
    Department of Biochemistry and Molecular Biology, Zhongshan Medical College, Sun Yat Sen University, Guangdong, People s Republic of China
    BMB Rep 41:765-70. 2008
    ..Taken together, these results indicate that hyperactive melanocytes can be inhibited by altering Stathmin 1 expression...
  73. doi request reprint Synthesis and crystal structure of two new dinuclear cobalt(II) complexes interaction with HeLa cells
    En Jun Gao
    Laboratory of Coordination Chemistry, Shenyang University of Chemical Technology, Shenyang Street, Shenyang 110142, People s Republic of China
    Eur J Med Chem 46:160-7. 2011
    ..The complexes exhibit a higher cytotoxicity against tumor cells as against normal cells in vitro. Further more, the apoptotic tests indicate that the complexes have an apoptotic effect on HeLa cells...
  74. doi request reprint Identification of EFEMP2 as a Serum Biomarker for the Early Detection of Colorectal Cancer with Lectin Affinity Capture Assisted Secretome Analysis of Cultured Fresh Tissues
    Ling Yao
    School of Biomedical Engineering and Med X Research Institute and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
    J Proteome Res 11:3281-94. 2012
    ..923 and 0.728, respectively. These results indicated EFEMP2 is a promising serum biomarker for CRC early detection. ..
  75. doi request reprint Stabilities and structures of islet amyloid polypeptide (IAPP22-28) oligomers: From dimer to 16-mer
    Jingjing Guo
    School of Pharmacy, Lanzhou University, Lanzhou 730000, China State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China Department of Chemistry, Lanzhou University, Lanzhou 730000, China
    Biochim Biophys Acta 1840:357-66. 2014
    ..The formation of amyloid fibrils is associated with many age-related degenerative diseases. Nevertheless, the molecular mechanism that directs the nucleation of these fibrils is not fully understood...
  76. ncbi request reprint Proteomic Analysis of Two Metabolic Proteins with Potential to Translocate to Plasma Membrane Associated with Tumor Metastasis Development and Drug Targets
    Ting Xue
    School of Biomedical Engineering and Med X Research Institute, Shanghai Jiao Tong University, Shanghai, China
    J Proteome Res . 2013
    ..This alteration of localization along with differential expressions might be necessary for metastasis development. Potentially, FASN and NSDHL could serve as drug targets in new antimetastasis therapy...
  77. pmc Complex sputum microbial composition in patients with pulmonary tuberculosis
    Zelin Cui
    Department of Medical Microbiology and Parasitology, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, China
    BMC Microbiol 12:276. 2012
    ..The 16S rRNA V3 hyper-variable regions were amplified using bar-coded primers and pyro-sequenced using Roche 454 FLX...
  78. pmc In silico identification of a multi-functional regulatory protein involved in Holliday junction resolution in bacteria
    Yan Zhang
    Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    BMC Syst Biol 6:S20. 2012
    ..Different Holliday junction resolution systems and enzymes have been characterized from all three domains of life. In bacteria, the RuvABC complex is the most important resolution system...
  79. doi request reprint MAFIP is a tumor suppressor in cervical cancer that inhibits activation of the nuclear factor-kappa B pathway
    Yang Li
    State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China
    Cancer Sci 102:2043-50. 2011
    ..In contrast, knockdown of MAFIP by siRNA activated the NF-κB pathway and promoted cell proliferation. These data suggest MAFIP functions as a tumor suppressor in cervical cancer in part by inhibiting activation of the NF-κB pathway...
  80. pmc Sputum microbiota associated with new, recurrent and treatment failure tuberculosis
    Jing Wu
    Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China
    PLoS ONE 8:e83445. 2013
    ..These findings indicate that lung microbiota may play a role in pathogenesis and treatment outcome of TB and may need to be taken into consideration for improved treatment and control of TB in the future. ..
  81. pmc An integrated approach to identify causal network modules of complex diseases with application to colorectal cancer
    Zhenshu Wen
    Key Laboratory of Systems Biology, SIBS Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    J Am Med Inform Assoc 20:659-67. 2013
    ..The limitation of relying on gene expression data alone highlights the need to develop new approaches that can explore various data to reflect the casual relationship between network modules and disease traits...
  82. pmc Potential of RAS inhibition to improve metabolic bone disorders
    Yoseph Gebru
    Center for Systems Biomedical Sciences, University of Shanghai for Science and Technology, Shanghai 200093, China
    Biomed Res Int 2013:932691. 2013
    ....
  83. doi request reprint Understanding the molecular mechanism of the broad and potent neutralization of HIV-1 by antibody VRC01 from the perspective of molecular dynamics simulation and binding free energy calculations
    Yan Zhang
    School of Pharmacy, Lanzhou University, Lanzhou, 730000, China
    J Mol Model 18:4517-27. 2012
    ..This information can be used to guide the design of vaccines and small molecule inhibitors...
  84. doi request reprint Lipid nanoparticles for chemotherapeutic applications: strategies to improve anticancer efficacy
    Xia Lin
    Shenyang Pharmaceutical University, Department of Pharmaceutics Science, People s Republic of China
    Expert Opin Drug Deliv 9:767-81. 2012
    ..e., solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs)) have been shown to provide a favorable means for efficiently delivering drugs to tumor sites, while minimizing their side effects...
  85. pmc Crystal structure of the cysteine desulfurase DndA from Streptomyces lividans which is involved in DNA phosphorothioation
    Fukun Chen
    State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
    PLoS ONE 7:e36635. 2012
    ....
  86. doi request reprint Involvement of estrogen in rapid pain modulation in the rat spinal cord
    Yan Zhang
    Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, China
    Neurochem Res 37:2697-705. 2012
    ..These results indicate that estrogen acutely facilitates nociceptive transmission in the spinal cord via activation of membrane-bound estrogen receptors...
  87. doi request reprint The application of laser microdissection to profiling fungal pathogen gene expression in planta
    Wei Hua Tang
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    Methods Mol Biol 835:219-36. 2012
    ....
  88. doi request reprint Fine tuning micellar core-forming block of poly(ethylene glycol)-block-poly(ε-caprolactone) amphiphilic copolymers based on chemical modification for the solubilization and delivery of doxorubicin
    Jinliang Yan
    Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, China
    Biomacromolecules 12:2562-72. 2011
    ..Taken together, the introduction of CABCL in the core-forming block of mPEG-b-PCL resulted in micelles with superior properties, which hold great promise for drug delivery applications...
  89. doi request reprint Soil Pseudomonas community structure and its antagonism towards Rhizoctonia solani under the stress of acetochlor
    Minna Wu
    Key Laboratory of Terrestrial Ecological Process, Institute of Applied Ecology, Chinese Academy of Science, 110016, Shenyang, People s Republic of China
    Bull Environ Contam Toxicol 83:313-7. 2009
    ..The diversity of Pseudomonas and the amount of isolated Pseudomonas strains with antagonistic activity decreased with an increasing acetochlor concentration, and the toxic effect of acetochlor reached to a steady level at 150-250 mg/kg...
  90. doi request reprint Side population in oral squamous cell carcinoma possesses tumor stem cell phenotypes
    Ping Zhang
    Department of Oral and Maxillofacial Surgery, Ninth People s Hospital, School of Stomatology, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, China
    Cancer Lett 277:227-34. 2009
    ..These findings provide the first evidence that SP in OCC possesses tumor stem cell phenotypes and may play an important role in OCC tumorigenesis...
  91. doi request reprint Rosiglitazone attenuates development of polycystic kidney disease and prolongs survival in Han:SPRD rats
    Bing Dai
    Kidney Institute of PLA, Changzheng Hospital, Second Military Medical University, Shanghai, China
    Clin Sci (Lond) 119:323-33. 2010
    ....
  92. doi request reprint Programmed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8+ T lymphocytes in human non-small cell lung cancer
    Yan Zhang
    Department of Laboratory Diagnosis, Changhai Hospital, Second Military Medical University, Shanghai, China
    Cell Mol Immunol 7:389-95. 2010
    ..These data provide direct evidence that the PD-1/PD-L1 pathway is involved in CD8+ T-cell dysfunction in NSCLC patients. Moreover, blocking this pathway provides a potential therapy target in lung cancer...
  93. doi request reprint Regulation of intracellular decorin via proteasome degradation in rat mesangial cells
    Huijuan Wu
    Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, China
    J Cell Biochem 111:1010-9. 2010
    ....
  94. doi request reprint Characterization of a bifunctional enzyme with (p)ppGpp-hydrolase/synthase activity in Leptospira interrogans
    Ping He
    Department of Microbiology and Parasitology, Institutes of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    FEMS Microbiol Lett 348:133-42. 2013
    ..interrogans contain a single Rel-like bifunctional protein, RelLin , which plays an important role in maintaining the basal level of (p)ppGpp in the cell potentially contributing to the regulation of bacterial stress response...
  95. pmc Kinase AKT controls innate immune cell development and function
    Yan Zhang
    Department of Immunology, Shanghai Medical College, Fudan University, Shanghai, China Shenyang Agriculture University, Shenyang, China
    Immunology 140:143-52. 2013
    ..The purpose of this review is to illustrate the immune modulating effects of kinase AKT on innate immune cell development, survival and function. ..
  96. doi request reprint Meta-analysis of the relation between vitamin D receptor gene BsmI polymorphism and susceptibility to ovarian cancer
    Yan Zhang
    Department of Gynecology, Fourth Affiliated Hospital, China Medical University, Shenyang, 110032, China
    Tumour Biol 34:3317-21. 2013
    ..This meta-analysis suggests that there is no association between VDR BsmI polymorphism and susceptibility to ovarian cancer in Caucasians. Future studies from Asians or Africans are needed to further assess the above association. ..
  97. doi request reprint Interleukin-17 enhances the production of interferon-γ and tumour necrosis factor-α by bone marrow T lymphocytes from patients with lower risk myelodysplastic syndromes
    Zheng Zhang
    Sixth People s Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China
    Eur J Haematol 90:375-84. 2013
    ..However, little is known about the role of IL-17 in MDS-associated immune dysfunction...
  98. pmc Tumor necrosis factor-α induced protein 8 polymorphism and risk of non-Hodgkin's lymphoma in a Chinese population: a case-control study
    Yan Zhang
    Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China
    PLoS ONE 7:e37846. 2012
    ..To evaluate the role of such genetic variations in risk of NHL, we conducted a case-control study of 514 NHL patients and 557 cancer-free controls in a Chinese population...
  99. doi request reprint Ephedrine hydrochloride protects mice from LPS challenge by promoting IL-10 secretion and inhibiting proinflammatory cytokines
    Yuejuan Zheng
    Department of Immunology and Microbiology, Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Int Immunopharmacol 13:46-53. 2012
    ..This study provides a potential usage of EH in autoimmunologic diseases or other severe inflammations...
  100. doi request reprint Cyclopropylmethyl palladium species from carbene migratory insertion: new routes to 1,3-butadienes
    Lei Zhou
    Beijing National Laboratory of Molecular Sciences BNLMS and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China
    Org Lett 14:922-5. 2012
    ..In both approaches migratory insertion of Pd carbene is the key process. These transformations constitute new approaches toward 1,3-butadiene derivatives...
  101. pmc Discovery of IL-18 as a novel secreted protein contributing to doxorubicin resistance by comparative secretome analysis of MCF-7 and MCF-7/Dox
    Ling Yao
    School of Biomedical Engineering and Med X Research Institute, Shanghai Jiao Tong University, Shanghai, China
    PLoS ONE 6:e24684. 2011
    ..We sought to systematically characterize secreted proteins associated with drug resistance, which may represent potential serum biomarkers or novel drug targets...