Zhiming Yuan


Country: China


  1. Zou J, Xie X, Wang Q, Dong H, Lee M, Kang C, et al. Characterization of dengue virus NS4A and NS4B protein interaction. J Virol. 2015;89:3455-70 pubmed publisher
    ..The study has advanced our knowledge of the molecular function of flavivirus NS4A and NS4B proteins. The results also suggest that inhibitors of the NS4A-NS4B interaction could be pursued for flavivirus antiviral development. ..
  2. Tian S, Xiong H, Geng P, Yuan Z, Hu X. CesH Represses Cereulide Synthesis as an Alpha/Beta Fold Hydrolase in Bacillus cereus. Toxins (Basel). 2019;11: pubmed publisher
    ..These results help us to understand the regulation of cereulide production and provide clues for developing control measurements. ..
  3. Xia H, Zhao N, Zhao L, Wang Y, Zhao W, Yuan Z. Rapid detection of Banna virus by reverse transcription-loop-mediated isothermal amplification (RT-LAMP). Int J Infect Dis. 2019;78:93-98 pubmed publisher
    ..Our findings present a rapid, sensitive and specific RT-LAMP assay that can be applied for BAV detection in clinical or field samples in the future. ..
  4. Geng P, Wan X, Cheng J, Yuan Z, Hu X. vB_LspM-01: a novel myovirus displaying pseudolysogeny in Lysinibacillus sphaericus C3-41. Appl Microbiol Biotechnol. 2018;102:10691-10702 pubmed publisher
    ..The mitomycin C induction helped the propagation and lysogeny-lysis switch of vB_LspM-01. The study demonstrated that vB_LspM-01 can be present in a pseudolysogenic state in L. sphaericus C3-41 populations. ..
  5. Xia H, Liu H, Zhao L, Atoni E, Wang Y, Yuan Z. First Isolation and Characterization of a Group C Banna Virus (BAV) from Anopheles sinensis Mosquitoes in Hubei, China. Viruses. 2018;10: pubmed publisher
    ..Our findings extend the knowledge about the genomic diversity and potential vectors/hosts of BAVs and will improve understanding of the relationships between genetic variation and pathogenicity. ..
  6. Liu X, Liu Y, Zhang Q, Zhang B, Xia H, Yuan Z. Homologous RNA secondary structure duplications in 3' untranslated region influence subgenomic RNA production and replication of dengue virus. Virology. 2018;524:114-126 pubmed publisher
  7. Ge Y, Zhao N, Hu X, Shi T, Cai Q, Yuan Z. A novel transcriptional activator, tubX, is required for the stability of Bacillus sphaericus mosquitocidal plasmid pBsph. J Bacteriol. 2014;196:4304-14 pubmed publisher
    ..These results suggested that TubX positively regulates tubRZ-Bs transcription by interfering with TubR-Bs-mediated repression and binding directly to the tubRZ-Bs promoter region. ..
  8. Fu P, Ge Y, Hu Y, Yuan Z, Hu X. A toxin-antitoxin system is essential for the stability of mosquitocidal plasmid pBsph of Lysinibacillus sphaericus. Microbiol Res. 2018;214:114-122 pubmed publisher
    ..The data indicate that the plasmid maintenance system on pBsph includes orf9-orf10 TA system. ..
  9. Xia H, Wang Y, Atoni E, Zhang B, Yuan Z. Mosquito-Associated Viruses in China. Virol Sin. 2018;33:5-20 pubmed publisher
    ..This review aims to systematically outline the history, characteristics, distribution, and/or current epidemic status of mosquito-associated viruses in China. ..

More Information


  1. Liu S, Deng C, Yuan Z, Rayner S, Zhang B. Identifying the pattern of molecular evolution for Zaire ebolavirus in the 2014 outbreak in West Africa. Infect Genet Evol. 2015;32:51-9 pubmed publisher
    ..However, a more balanced sample set and next generation sequencing datasets would help achieve a clearer understanding at the genetic level of how the virus is evolving and adapting to new conditions. ..
  2. Shi T, Ge Y, Zhao N, Hu X, Yuan Z. Polyphosphate kinase of Lysinibacillus sphaericus and its effects on accumulation of polyphosphate and bacterial growth. Microbiol Res. 2015;172:41-7 pubmed publisher
    ..These results suggested that PPK plays a role in polyP accumulation and expression of genes involved in BCAAs biosynthesis, providing a hint for further understanding of the role of PPK in nutritional limitation in L. sphaericus. ..
  3. Zhao N, Ge Y, Shi T, Hu X, Yuan Z. Collagen-like glycoprotein BclS is involved in the formation of filamentous structures of the Lysinibacillus sphaericus exosporium. Appl Environ Microbiol. 2014;80:6656-63 pubmed publisher
    ..These results suggested novel roles of collagen-like protein in exosporium assembly and spore germination, providing a hint for a further understanding of the genetic basis of the high level of persistence of Bin toxins in nature. ..
  4. Zai J, Yi Y, Xia H, Zhang B, Yuan Z. A new strategy for full-length Ebola virus glycoprotein expression in E.coli. Virol Sin. 2016;31:500-508 pubmed publisher
  5. Hu Y, Cai Q, Tian S, Ge Y, Yuan Z, Hu X. Regulator DegU is required for multicellular behavior in Lysinibacillus sphaericus. Res Microbiol. 2018;169:177-187 pubmed publisher
    ..It was concluded that DegU is a global transcriptional regulator on cell swarming motility, biofilm formation, sporulation and virulence in L. sphaericus. ..
  6. Xia H, Wang Y, Shi C, Atoni E, Zhao L, Yuan Z. Comparative Metagenomic Profiling of Viromes Associated with Four Common Mosquito Species in China. Virol Sin. 2018;33:59-66 pubmed publisher
    ..This investigation provides a basis for a comprehensive knowledge on the mosquito virome status in China. ..
  7. Ge S, Liu L, Xue Q, Yuan Z. Effects of exogenous aerobic bacteria on methane production and biodegradation of municipal solid waste in bioreactors. Waste Manag. 2016;55:93-8 pubmed publisher
  8. Xu K, Yuan Z, Rayner S, Hu X. Genome comparison provides molecular insights into the phylogeny of the reassigned new genus Lysinibacillus. BMC Genomics. 2015;16:140 pubmed publisher
    ..sphaericus toxin genes were acquired by horizontal gene transfer (HGT), and (2) capture and loss of plasmids occurs in the population, which plays an important role in the transmission of binA/binB. ..
  9. Atoni E, Wang Y, Karungu S, Waruhiu C, Zohaib A, Obanda V, et al. Metagenomic Virome Analysis of Culex Mosquitoes from Kenya and China. Viruses. 2018;10: pubmed publisher
    ..Our study is preliminary but contributes to growing and much needed knowledge, as mosquito viromes could be manipulated to prevent and control pathogenic arboviruses. ..
  10. Zhao L, Xia H, Wang Y, Evans A, Zhang Y, Yuan Z. Complete Genome Sequence of a New Strain of Tanay Virus, Isolate YN15_103_01, from Yunnan, China. Genome Announc. 2018;6: pubmed publisher
    ..Sequence analysis showed that it shares a 79% nucleotide sequence identity with the only other previously reported strains of Tanay virus, which were isolated from the Philippines. ..
  11. Geng P, Hu Y, Zhou G, Yuan Z, Hu X. Characterization of three autolysins with activity against cereulide-producing Bacillus isolates in food matrices. Int J Food Microbiol. 2017;241:291-297 pubmed publisher
    ..All the results revealed that the three autolysins might be potential candidates to control emetic B. cereus strains in different applications. ..
  12. Fu P, Ge Y, Wu Y, Zhao N, Yuan Z, Hu X. The LspC3-41I restriction-modification system is the major determinant for genetic manipulations of Lysinibacillus sphaericus C3-41. BMC Microbiol. 2017;17:116 pubmed publisher
  13. Wang Y, Xia H, Zhang B, Liu X, Yuan Z. Isolation and characterization of a novel mesonivirus from Culex mosquitoes in China. Virus Res. 2017;240:130-139 pubmed publisher
    ..Based on the phylogenetic and pairwise evolutionary distance analyses, the Yichang virus should be considered a new species belonging to a currently unassigned genus within the family Mesoniviridae. ..
  14. Deng C, Liu S, Zhou D, Xu L, Li X, Zhang P, et al. Development of Neutralization Assay Using an eGFP Chikungunya Virus. Viruses. 2016;8: pubmed publisher
    ..Importantly, we developed a novel and reliable eGFP-CHIKV reporter virus-based neutralization assay that could be used for rapid screening neutralizing antibodies against CHIKV. ..