Jiaoyang Yin

Summary

Country: China

Publications

  1. doi request reprint No evidence of association between the synonymous polymorphisms in XRCC1 and ERCC2 and breast cancer susceptibility among nonsmoking Chinese
    Jiaoyang Yin
    Shenyang Medical College, Shenyang, Liaoning Province, People s Republic of China
    Gene 503:118-22. 2012
  2. doi request reprint A specific diplotype defined by PPP1R13L rs1970764, CD3EAP rs967591 and ERCC1 rs11615 and lung cancer risk in a Chinese population
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of Liaoning Education Ministry Shenyang Medical College, Shenyang 110034, Liaoning Province, People s Republic of China
    Lung Cancer 76:286-91. 2012
  3. doi request reprint Hapmap-based evaluation of ERCC2, PPP1R13L, and ERCC1 and lung cancer risk in a Chinese population
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of Liaoning Education Ministry Shenyang Medical College, Shenyang, Liaoning Province, People s Republic of China
    Environ Mol Mutagen 53:239-45. 2012
  4. ncbi request reprint Genetic polymorphisms of DNA repair gene: XRCC1 Pro206Pro and Gln632Gln in a Chinese Han population
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of Liaoning Education Ministry, Shenyang Medical College, Shenyang, Liaoning Province, P R China
    Biochem Genet 45:815-21. 2007
  5. doi request reprint Haplotypes of nine single nucleotide polymorphisms on chromosome 19q13.2-3 associated with susceptibility of lung cancer in a Chinese population
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of University in Liaoning Province, Shenyang Medical College, Shenyang 110034, Liaoning Province, PR China
    Mutat Res 641:12-8. 2008
  6. doi request reprint HapMap-based study of the DNA repair gene ERCC2 and lung cancer susceptibility in a Chinese population
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of University in Liaoning Province, Shenyang Medical College, Shenyang, Liaoning Province, People s Republic of China
    Carcinogenesis 30:1181-5. 2009
  7. ncbi request reprint A haplotype encompassing the variant allele of DNA repair gene polymorphism ERCC2/XPD Lys751Gln but not the variant allele of Asp312Asn is associated with risk of lung cancer in a northeastern Chinese population
    Jiaoyang Yin
    Department of Medical Genetics, Shenyang Medical College, No 146, N Huanghe St, Yuhong District, Shenyang 110034, Liaoning Province, People s Republic of China
    Cancer Genet Cytogenet 175:47-51. 2007
  8. ncbi request reprint The DNA repair gene XRCC1 and genetic susceptibility of lung cancer in a northeastern Chinese population
    Jiaoyang Yin
    Department of Medical Genetics, Shenyang Medical College, Shenyang 110034, Liaoning Province, PR China
    Lung Cancer 56:153-60. 2007
  9. ncbi request reprint Polymorphism of the DNA repair gene ERCC2 Lys751Gln and risk of lung cancer in a northeastern Chinese population
    Jiaoyang Yin
    Department of Medical Genetics, Shenyang Medical College, No 146, N Huanghe St, Yuhong District, Shenyang 110034, Liaoning Province, PR China
    Cancer Genet Cytogenet 169:27-32. 2006
  10. ncbi request reprint Lack of association between DNA repair gene ERCC1 polymorphism and risk of lung cancer in a Chinese population
    Jiaoyang Yin
    Department of Medical Genetics, Shenyang Medical College, Shenyang 110034, Liaoning Province, People s Republic of China
    Cancer Genet Cytogenet 164:66-70. 2006

Collaborators

Detail Information

Publications20

  1. doi request reprint No evidence of association between the synonymous polymorphisms in XRCC1 and ERCC2 and breast cancer susceptibility among nonsmoking Chinese
    Jiaoyang Yin
    Shenyang Medical College, Shenyang, Liaoning Province, People s Republic of China
    Gene 503:118-22. 2012
    ..The two loci were at weak linkage disequilibrium (D' value=0.244, P=0.07). The present data suggest that XRCC1 Pro206Pro and ERCC2 Arg156Arg do not substantially influence breast cancer susceptibility among nonsmoking Chinese...
  2. doi request reprint A specific diplotype defined by PPP1R13L rs1970764, CD3EAP rs967591 and ERCC1 rs11615 and lung cancer risk in a Chinese population
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of Liaoning Education Ministry Shenyang Medical College, Shenyang 110034, Liaoning Province, People s Republic of China
    Lung Cancer 76:286-91. 2012
    ....
  3. doi request reprint Hapmap-based evaluation of ERCC2, PPP1R13L, and ERCC1 and lung cancer risk in a Chinese population
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of Liaoning Education Ministry Shenyang Medical College, Shenyang, Liaoning Province, People s Republic of China
    Environ Mol Mutagen 53:239-45. 2012
    ..12e-005 and P = 4.82e-006, respectively). The results indicate that the biologically relevant genetic variation may be located at or near the subregion spanning from ERCC2 inton19 rs1799787 to PPP1R13L intron8 rs2070830...
  4. ncbi request reprint Genetic polymorphisms of DNA repair gene: XRCC1 Pro206Pro and Gln632Gln in a Chinese Han population
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of Liaoning Education Ministry, Shenyang Medical College, Shenyang, Liaoning Province, P R China
    Biochem Genet 45:815-21. 2007
    ..They showed marked ethnic group differences. This study provides the first analysis of the distribution of allele frequency for XRCC1 Pro206Pro and Gln632Gln in a Chinese population...
  5. doi request reprint Haplotypes of nine single nucleotide polymorphisms on chromosome 19q13.2-3 associated with susceptibility of lung cancer in a Chinese population
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of University in Liaoning Province, Shenyang Medical College, Shenyang 110034, Liaoning Province, PR China
    Mutat Res 641:12-8. 2008
    ..This result supports the hypothesis that the sub-region is important for lung cancer susceptibility. Haplotype studies using larger study groups will be required to obtain conclusive results...
  6. doi request reprint HapMap-based study of the DNA repair gene ERCC2 and lung cancer susceptibility in a Chinese population
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of University in Liaoning Province, Shenyang Medical College, Shenyang, Liaoning Province, People s Republic of China
    Carcinogenesis 30:1181-5. 2009
    ..These results suggested that the risk subhaplotypes cosegregate with one or more biologically functional polymorphisms. Our results provide evidence to support a role for ERCC2 in lung cancer development in a Chinese population...
  7. ncbi request reprint A haplotype encompassing the variant allele of DNA repair gene polymorphism ERCC2/XPD Lys751Gln but not the variant allele of Asp312Asn is associated with risk of lung cancer in a northeastern Chinese population
    Jiaoyang Yin
    Department of Medical Genetics, Shenyang Medical College, No 146, N Huanghe St, Yuhong District, Shenyang 110034, Liaoning Province, People s Republic of China
    Cancer Genet Cytogenet 175:47-51. 2007
    ..Studies including larger sample sizes are needed to elucidate the effects of these polymorphisms on lung cancer risk in this northeastern Chinese population...
  8. ncbi request reprint The DNA repair gene XRCC1 and genetic susceptibility of lung cancer in a northeastern Chinese population
    Jiaoyang Yin
    Department of Medical Genetics, Shenyang Medical College, Shenyang 110034, Liaoning Province, PR China
    Lung Cancer 56:153-60. 2007
    ..To our knowledge, this is first report that XRCC1 Pro206Pro influences cancer risk...
  9. ncbi request reprint Polymorphism of the DNA repair gene ERCC2 Lys751Gln and risk of lung cancer in a northeastern Chinese population
    Jiaoyang Yin
    Department of Medical Genetics, Shenyang Medical College, No 146, N Huanghe St, Yuhong District, Shenyang 110034, Liaoning Province, PR China
    Cancer Genet Cytogenet 169:27-32. 2006
    ..In conclusion, our results suggest that ERCC2 Lys751Gln(C) allele is a potential risk marker for lung cancer in this northeastern Chinese population...
  10. ncbi request reprint Lack of association between DNA repair gene ERCC1 polymorphism and risk of lung cancer in a Chinese population
    Jiaoyang Yin
    Department of Medical Genetics, Shenyang Medical College, Shenyang 110034, Liaoning Province, People s Republic of China
    Cancer Genet Cytogenet 164:66-70. 2006
    ..001). No statistically significant effects of age, histological subtype or smoking were found. These findings suggest that ERCC1 Asn118Asn (G19007A) polymorphism may play a limited role for lung cancer in this Chinese population...
  11. doi request reprint The polymorphism of DNA repair gene ERCC2/XPD Arg156Arg and susceptibility to breast cancer in a Chinese population
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of University in Liaoning Province, Shenyang Medical College, Shenyang, Liaoning, China
    Biochem Genet 47:582-90. 2009
    ..05). There were no differences in risk estimates in relation to menopause and occurrence of breast cancer. Our findings do not suggest that ERCC2/XPD Arg156Arg contributes to breast cancer susceptibility in a Chinese population...
  12. doi request reprint HapMap-based study of a region encompassing ERCC1 and ERCC2 related to lung cancer susceptibility in a Chinese population
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of University in Liaoning Province, Shenyang Medical College, Shenyang 110034, Liaoning Province, People s Republic of China
    Mutat Res 713:1-7. 2011
    ..These data suggest that common genetic variations in ERCC1 may influence increased risk of smoking-related lung cancer and one of the causative effectors may locate around or within ERCC2...
  13. doi request reprint Association of DNA repair gene XRCC1 and lung cancer susceptibility among nonsmoking Chinese women
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of University in Liaoning Province, Shenyang Medical College, Shenyang 110034, Liaoning Province, PR China
    Cancer Genet Cytogenet 188:26-31. 2009
    ..01, 95%CI=1.01-8.92, P=0.04). These findings further suggest that the polymorphisms XRCC1 Arg194Trp and Pro206Pro or the haplotype encompassing the variant alleles may contribute to susceptibility of lung cancer in a Chinese population...
  14. doi request reprint Effects of PPP1R13L and CD3EAP variants on lung cancer susceptibility among nonsmoking Chinese women
    Jiaoyang Yin
    Key Laboratory of Environment and Population Health of Liaoning Education Ministry Shenyang Medical College, Shenyang 110034, Liaoning Province, People s Republic of China
    Gene 524:228-31. 2013
    ..In conclusion, this study suggests that CD3EAP rs967591 variant allele carriers are at increased susceptibility of lung cancer among nonsmoking Chinese women...
  15. ncbi request reprint Polymorphisms of DNA repair genes: ERCC1 G19007A and ERCC2/XPD C22541A in a northeastern Chinese population
    Jiaoyang Yin
    Institute of Cell Biology, Zhejiang University, Hangzhou, 310031, Zhejiang, P R China
    Biochem Genet 43:543-8. 2005
    ..The low A-allele frequency of ERCC1 G19007A in the Chinese population may suggest that the genetic contribution to cancer risk differs substantially between ethnic groups...
  16. ncbi request reprint The DNA repair gene ERCC2/XPD polymorphism Arg 156Arg (A22541C) and risk of lung cancer in a Chinese population
    Jiaoyang Yin
    Institute of Cell Biology, Zhejiang University, Hangzhou 310031, Zhejiang Province, People s Republic of China
    Cancer Lett 223:219-26. 2005
    ..60; 95% CI=1.52-20.56) (P=0.005) among never-smokers only. These results suggest a possible gene-environment interaction. This is the first study to report a significant association of XPD Arg156Arg with risk of lung cancer...
  17. ncbi request reprint Twelve single nucleotide polymorphisms on chromosome 19q13.2-13.3: linkage disequilibria and associations with basal cell carcinoma in Danish psoriatic patients
    Jiaoyang Yin
    Institute of Human Genetics, University of Aarhus, Aarhus C DK 8000, Denmark
    Biochem Genet 41:27-37. 2003
    ..The combined studies suggest that genetic variation in nucleotide excision repair is of importance for the development of BCC...
  18. ncbi request reprint Multiple single nucleotide polymorphisms on human chromosome 19q13.2-3 associate with risk of Basal cell carcinoma
    Jiaoyang Yin
    Institute of Human Genetics, University of Aarhus, DK 8000 Aarhus C, Denmark
    Cancer Epidemiol Biomarkers Prev 11:1449-53. 2002
    ....
  19. ncbi request reprint Association of chromosome 19q13.2-3 haplotypes with basal cell carcinoma: tentative delineation of an involved region using data for single nucleotide polymorphisms in two cohorts
    Eszter Rockenbauer
    Institute of Human Genetics, The Bartholin Building, University of Aarhus, DK 8000 Aarhus C, Denmark
    Carcinogenesis 23:1149-53. 2002
    ....
  20. ncbi request reprint Rapid genotyping of human ERCC1 exon 4 polymorphism with fluorescence analysis using fluorophore-labeled hybridization probes and a lightcycler
    Jiaoyang Yin
    Institute of Human Genetics, University of Aarhus, Denmark
    Biochem Genet 40:143-8. 2002