Affiliation: Yangzhou University
El Sayed A, Zhang Z, Zhang L, Liu Z, Abbott L, Zhang Y, et al
. Pluripotent state induction in mouse embryonic fibroblast using mRNAs of reprogramming factors. Int J Mol Sci. 2014;15:21840-64 pubmed publisher
Zhang Z, Elsayed A, Shi Q, Zhang Y, Zuo Q, Li D, et al
. Crucial genes and pathways in chicken germ stem cell differentiation. J Biol Chem. 2015;290:13605-21 pubmed publisher
..Our results yield clues to the mechanistic basis of male germ cell differentiation and provide an important reference for further studies. ..
Wang X, Chen T, Zhang Y, Li B, Xu Q, Song C. Isolation and Culture of Pig Spermatogonial Stem Cells and Their in Vitro Differentiation into Neuron-Like Cells and Adipocytes. Int J Mol Sci. 2015;16:26333-46 pubmed publisher
..qPCR results also support this conclusion. The nervous tissue markers genes, Nestin and Î²-tubulin, were expressed in the neuron-like cells and the adipocyte marker genes, PPARÎ³ and C/EBPÎ±, were expressed in the adipocytes. ..
Wang X, Wang Y, Zuo Q, Li D, Zhang W, Lian C, et al
. The synergistic effect of 5Azadc and TSA on maintenance of pluripotency of chicken ESCs by overexpression of NANOG gene. In Vitro Cell Dev Biol Anim. 2016;52:488-96 pubmed publisher
..Thus, we showed that 5-Azadc and TSA can effectively maintain chicken ESC pluripotency in vitro by increasing NANOG gene expression. ..
Li D, Wang M, Cheng S, Zhang C, Wang Y, Zhang W, et al
. CYP1A1 based on metabolism of xenobiotics by cytochrome P450 regulates chicken male germ cell differentiation. In Vitro Cell Dev Biol Anim. 2017;53:293-303 pubmed publisher
Li D, Cheng S, Zhang W, Wang M, Sun C, Zhang C, et al
. Hedgehog-Gli1 signaling regelates differentiation of chicken (Gallus gallus) embryonic stem cells to male germ cells. Anim Reprod Sci. 2017;182:9-20 pubmed publisher
..Collectively, these results uncovered a novel function of Gli1 and demonstrated Hedgehog-Gli1 signaling pathway involved in chicken male germ cell differentiation, where it acts as a facilitator. ..