Research Topics
Genomes and Genes | Songshu MengSummaryAffiliation: Yangzhou University Country: China Publications
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Detail Information
Publications
Targeting autophagy to enhance oncolytic virus-based cancer therapySongshu Meng
Dalian Medical University Cancer Center, Institute of Cancer Stem Cell, 9 Lvshun Road South, Dalian 116044, China
Expert Opin Biol Ther 13:863-73. 2013..Expert opinion: Targeting the cellular autophagy machinery could be explored as a new therapeutic strategy to enhance OV-mediated antitumor effects in the future...
Tyrosines 303/343/353 within the Sprouty-related domain of Spred2 are essential for its interaction with p85 and inhibitory effect on Ras/ERK activationSongshu Meng
College of Bioscience and Biotechnology, Yangzhou University, Yangzhou 225009, China
Int J Biochem Cell Biol 44:748-58. 2012....
Avian reovirus triggers autophagy in primary chicken fibroblast cells and Vero cells to promote virus productionSongshu Meng
Ministry of Education Key Lab for Avian Preventive Medicine, College of Veterinary Medicine, Yangzhou University, Wenhuidong Road No 48, Yangzhou, 225009, China
Arch Virol 157:661-8. 2012..Altogether, our studies strongly suggest that autophagy may play a critical role in determining viral yield during ARV infection...
Biphasic activation of PI3K/Akt and MAPK/Erk1/2 signaling pathways in bovine herpesvirus type 1 infection of MDBK cellsLiqian Zhu
College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China
Vet Res 42:57. 2011..This revealed for the first time that BoHV-1 actively induced both PI3K/Akt and MAPK/Erk1/2 signaling pathways, and the activation of PI3K was important for fully efficient replication, especially for the post-entry stage...
[Mechanisms of in vitro anti-tumor effects of a Newcastle disease virus]Songshu Meng
College of Bioscience and Biotechnology, Yangzhou University, Yangzhou 225009, China
Wei Sheng Wu Xue Bao 49:512-7. 2009..To obtain Newcastle disease virus (NDV) strains with high in vitro anti-tumor effect for construction of recombinant NDV for clinical therapy...
Participation of Gab1 and Gab2 in IL-22-mediated keratinocyte proliferation, migration, and differentiationXiaofang Zhu
Department of Dermatology of Clinical Medical School, Yangzhou University, Yangzhou, China
Mol Cell Biochem 369:255-66. 2012..Altogether, these data underscore the critical roles of Gab1 and Gab2 in IL-22-mediated HaCaT cell proliferation, migration, and differentiation...
Association of Shp2 with phosphorylated IL-22R1 is required for interleukin-22-induced MAP kinase activationSongshu Meng
College of Bioscience and Biotechnology, Yangzhou University, Yangzhou 225009, China
J Mol Cell Biol 2:223-30. 2010..These results reveal a critical role of Shp2 in IL-22 mediated signal transduction pathways...
Apoptin enhances the oncolytic properties of Newcastle disease virusYantao Wu
Ministry of Education Key Lab for Avian Preventive Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China
Intervirology 55:276-86. 2012..In this study, we tested the hypothesis that apoptin enhances NDV-mediated tumor cell death...
Newcastle disease virus induces apoptosis in cisplatin-resistant human lung adenocarcinoma A549 cells in vitro and in vivoSongshu Meng
State Key Laboratory of Veterinary Biotechnology, Harbin 150001, China
Cancer Lett 317:56-64. 2012..Furthermore, NDV displayed oncolytic effects in a mouse A549/DDP lung cancer model. Collectively, our data indicate that NDV could overcome the cisplatin resistance in lung cancer cells in vitro and in vivo...
Interleukin-22 protects rat PC12 pheochromocytoma cells from serum deprivation-induced cell deathYongchun Liu
Northern Jiangsu People s Hospital, Nantong West Road No 98, Yangzhou, 225001, China
Mol Cell Biochem 371:137-46. 2012..To our knowledge, this is the first report showing that IL-22 confers a neuroprotective function, which may provide a new therapeutic option for treatment of neurodegenerative diseases...
New alleles of chicken CD8 alpha and CD3d found in Chinese native and western breedsQinghai Hu
College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road, Yangzhou, Jiangsu 225009, China
Vet Immunol Immunopathol 120:223-33. 2007....
