Research Topics
Species | Yong YangSummaryCountry: China Publications
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Publications
Fourier-based analysis of moiré fringe patterns of superposed gratings in alignment of nanolithographyShaolin Zhou
Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu 610209, China
Opt Express 16:7869-80. 2008....
Extended dual-grating alignment method for optical projection lithographyWangfu Chen
State Key Laboratory of Optical Technologies for Microfabrication, Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu 610209, China
Appl Opt 49:708-13. 2010..Analytical results indicate that alignment is independent of the gap between wafer and mask, disturbance from the fluctuation in illumination can be neglected, and alignment resolution in subnanometers can be realized with this scheme...
Tilt-modulated spatial phase imaging method for wafer-mask leveling in proximity lithographyShaolin Zhou
State Key Laboratory of Optical Technologies for Microfabrication, Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu 610209, China
Opt Lett 35:3132-4. 2010..Finally, wafer-mask leveling can be achieved at only one spot with preserved accuracy. Computational and experimental results confirm that tilts at the magnitude of 10(-3) rad can be readily resolved by this method...
[Improvement on microwave technology of extracting polysaccharide from yacon leaves]Jing Wei Li
Sichuan Agricultural University, Institute of Maize Research, Ya an 625014, China
Zhong Yao Cai 30:1449-52. 2007....
N-glycosylation affects the adhesive function of E-Cadherin through modifying the composition of adherens junctions (AJs) in human breast carcinoma cell line MDA-MB-435Hongbo Zhao
Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, PR China
J Cell Biochem 104:162-75. 2008..These findings demonstrate that N-glycosylation may affect the adhesive function of E-cadherin through modifying the composition of AJs...
Localization of NGF and TrkA at mitotic apparatus in human glioma cell line U251Zhijian Zhang
School of Medicine, Jiangsu University, Jiangsu Zhenjiang 212001, China
Biochem Biophys Res Commun 337:68-74. 2005..The phosphorylated TrkA with the tyrosine kinase activity may phosphorylate the tubulin and promote the mitotic spindle assembly. By these mechanisms, NGF can modulate the mitosis of human glioma cells...
Protein phosphatase activity of PTEN inhibited the invasion of glioma cells with epidermal growth factor receptor mutation type III expressionXiu mei Cai
Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, China
Int J Cancer 117:905-12. 2005....
[Purification of colorectal cancer-associated antigen by immuno-affinity chromatography]Yong Yang
Department of Cell Biology, Fourth Military Medical University, Xi an 710032, China
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20:348-51. 2004..To purify and characterize the colorectal cancer-associated antigen from cultured colorectal cancer cells...
Localization of phosphorylated TrkA in carrier vesicles involved in its nuclear translocation in U251 cell lineAihua Gong
School of Medicine, Jiangsu University, Zhenjiang 212013, China
Sci China C Life Sci 50:141-6. 2007..Accordingly, our results suggested that such a series of membrane compartments might be involved in the pathway of nuclear translocation of the transmembrane receptor TrkA...
The catalyst-assisted synthesis of high quality CdS single-crystal nanowires through an epitaxy mechanismZengtao Liu
State Key Laboratory for Physical Chemistry of Solid Surface, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, PR China
J Nanosci Nanotechnol 7:3152-6. 2007..e., (0001)CdS // (111)Au, and [1210]CdS // [011]Au...
Gambogic acid inhibits angiogenesis through suppressing vascular endothelial growth factor-induced tyrosine phosphorylation of KDR/Flk-1Na Lu
Jiangsu Key Laboratory of Carcinogenesis and Intervention China Pharmaceutical University, Nanjing, PR China
Cancer Lett 258:80-9. 2007..Taken together, these findings strongly suggest that GA might be a structurally novel angiogenesis inhibitor...
A comparison of nLC-ESI-MS/MS and nLC-MALDI-MS/MS for GeLC-based protein identification and iTRAQ-based shotgun quantitative proteomicsYong Yang
U S Plant, Soil and Nutrition Laboratory, Tower Road, Ithaca, NY 14853, USA
J Biomol Tech 18:226-37. 2007....
[Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-beta1]Wei Guo
Department of Nephrology, Children s Hospital of Fudan University, Shanghai 200032, China
Zhonghua Yi Xue Za Zhi 87:1660-5. 2007..To illuminate the possible role of Prohibitin (PHB) in tubulointerstitial fibrosis...
Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytesYong Yang
Department of Physiology, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China
Cancer Lett 256:259-66. 2007..So GA might be a kind of highly effective anticancer drug candidate with low toxicity to normal tissue...
Dynamics of nitric oxide and peroxynitrite during global brain ischemia/reperfusion in rat hippocampus: NO-sensor measurement and modeling studyYong Yang
Department of Biomedical Engineering, Zhejiang University yuqun campus, Hangzhou, 310027, PR China
Neurochem Res 33:73-80. 2008..Results show the rate of NO formation has a great influence on peroxynitrite dynamics...
Endostar, a novel recombinant human endostatin, exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cellsYun Ling
Department of Physiology, China Pharmaceutical University, Nanjing 210009, China
Biochem Biophys Res Commun 361:79-84. 2007..Collectively, these data indicated the relationship between endostar and VEGF signal pathways and provided a molecular basis for the antiangiogenic effects of endostar...
Inhibition of glioblastoma growth and angiogenesis by gambogic acid: an in vitro and in vivo studyLei Qiang
Department of Physiology, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, People s Republic of China
Biochem Pharmacol 75:1083-92. 2008..Collectively, the current data indicated that GA may be of potential use in treatment of glioblastoma by apoptotic induction and antiangiogenic effects...
Posttranscriptional regulation of the telomerase hTERT by gambogic acid in human gastric carcinoma 823 cellsQing Zhao
Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, People s Republic of China
Cancer Lett 262:223-31. 2008..Collectively, we suggest that GA represses telomerase activity not only by repressing hTERT transcriptional activity via c-Myc but also by posttranslational modification of hTERT via Akt...
N-glycosylation at Asn residues 554 and 566 of E-cadherin affects cell cycle progression through extracellular signal-regulated protein kinase signaling pathwayHongbo Zhao
Key Laboratory of Glycoconjugate Research, Ministry of Health, Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032, China
Acta Biochim Biophys Sin (Shanghai) 40:140-8. 2008..These findings implied that N-glycosylation might be crucial for E-cadherin-mediated suppression of cell cycle progression...
Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochoreYong Yang
Hefei National Laboratory for Physical Sciences at Micro scale and University of Science and Technology of China, Hefei 230027, China
J Biol Chem 283:26726-36. 2008..Thus, we reason that HsMis13 phosphorylation by Aurora B is required for organizing a stable bi-oriented microtubule kinetochore attachment that is essential for faithful chromosome segregation in mitosis...
Microtubule depolymerization and phosphorylation of c-Jun N-terminal kinase-1 and p38 were involved in gambogic acid induced cell cycle arrest and apoptosis in human breast carcinoma MCF-7 cellsJing Chen
Jiangsu Key Laboratory of Carcinogenesis and Intervention China Pharmaceutical University, Nanjing, PR China
Life Sci 83:103-9. 2008..Taken together, our results suggested that GA depolymerized microtubules and elevated the phosphorylation levels of JNK1 and p38, which caused G2/M cell cycle arrest and apoptosis in MCF-7 cells...
Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCdelta phosphorylationHai Wei Zhang
Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, China
Eur J Pharmacol 591:7-12. 2008..Taken together, wogonin induced U-937 cells to undergo granulocytic differentiation and G1 phase arrest via PKCdelta phosphorylation-induced upregulation of p21 proteins...
Inhibition of alpha(4) integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with gambogic acidJie Zhao
Jiangsu Key Laboratory of Carcinogenesis and Intervention China Pharmaceutical University, Nanjing, PR China
Eur J Pharmacol 589:127-31. 2008..Thus we concluded for the first time that gambogic acid could inhibit the adhesion and migration of B16-F10 cells in vitro and in vivo, in which down-regulation of alpha(4) integrin expression was involved...
Endostar suppresses invasion through downregulating the expression of matrix metalloproteinase-2/9 in MDA-MB-435 human breast cancer cellsNa Lu
Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 210009 Nanjing, People s Republic of China
Exp Biol Med (Maywood) 233:1013-20. 2008..Additionally, endostar exerted an inhibitory effect on the phosphorylation of ERK1/2. Collectively, these data provided a molecular basis for the anti-invasive effects of endostar...
Biodegradable urethral stent in the treatment of post-traumatic urethral strictures in a war wound rabbit urethral modelWei Jun Fu
Department of Urology, Chinese People s Liberation Army General Hospital, Military Postgraduate Medical College, No 28 Fuxing road, Hai Dian District, Beijing 100853, People s Republic of China
Biomed Mater 2:263-8. 2007..There are distinct advantages in terms of safe, effective and less-invasive treatment for the reconstruction of post-traumatic urethral strictures...
Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2Na Lu
Jiangsu Key Laboratory of Carcinogenesis and Intervention China Pharmaceutical University, Nanjing 210009, People s Republic of China
Life Sci 82:956-63. 2008..Taken together, these findings strongly suggest that wogonin might be a promising antitumor drug...
Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expressionKun Zhang
Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, China
Cancer Sci 99:689-95. 2008..Taken together, the results reported here demonstrated that wogonin could promote the granulocytic differentiation of NB4 cells by up-regulating the expression of PLSCR1 gene...
Single-molecule diffusion study of activated EGFR implicates its endocytic pathwayZeyu Xiao
Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China
Biochem Biophys Res Commun 369:730-4. 2008..It provided supporting evidence for the occurrence of both clathrin-dependent and caveolae-dependent EGFR endocytosis...
Overexpression of integrin beta1 inhibits proliferation of hepatocellular carcinoma cell SMMC-7721 through preventing Skp2-dependent degradation of p27 via PI3K pathwayYi Fu
Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032, China
J Cell Biochem 102:704-18. 2007..Together, these results suggested that overexpression of integrin beta1 inhibited cell proliferation by preventing the Skp2-dependent degradation of p27(Kip1) via PI3K pathway...
Anti-hepatitis B virus activity of wogonin in vitro and in vivoQinglong Guo
Department of Physiology, China Pharmaceutical University, Nanjing, China
Antiviral Res 74:16-24. 2007..In conclusion, our results demonstrate that wogonin possesses potent anti-HBV activity both in vitro and in vivo. Currently, wogonin is under early development as an anti-HBV drug candidate...
The psoriasis disability index in Chinese patients: contribution of clinical and psychological variablesYong Yang
Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore, and the National Skin Center, Singapore
Int J Dermatol 44:925-9. 2005..Psychological factors are much stronger determinants of the PDI than demographic, disease related variables. Clinical management of the disease should consider both clinical and psychological factors...
Towards biologically conformal radiation therapy (BCRT): selective IMRT dose escalation under the guidance of spatial biology distributionYong Yang
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305-5847, USA
Med Phys 32:1473-84. 2005..The proposed formalism lays a technical foundation for BCRT and allows us to maximally exploit the technical capacity of IMRT to more intelligently escalate the radiation dose...
Involvement of CD147 in overexpression of MMP-2 and MMP-9 and enhancement of invasive potential of PMA-differentiated THP-1Jun Zhou
Department of Clinical Immunology, First Affiliated Hospital, Fourth Military Medical University, 17 Changlexilu, Xi an 710032, Shaanxi, P R China
BMC Cell Biol 6:25. 2005..We found in our study that CD147 played a very important role in this process...
Template guided self-assembling two-dimensional array of Au@SiO2 core-shell nanoparticles for room-temperature single electron transistorsYong Yang
Department of Materials Science and Engineering, Nagoya Institute of Technology, Showa, Nagoya 466-8555, Japan
J Nanosci Nanotechnol 5:179-83. 2005..The tunable single electron tunneling properties make the 2D array of Au@SiO2 composite nanoparticles an ideal candidate for planar single electron transistor devices...
Spectroscopic characterization of Au3+ biosorption by waste biomass of Saccharomyces cerevisiaeZhongyu Lin
State Key Laboratory for Physical Chemistry of Solid Surface, Department of Chemistry, Xiamen University, Xiamen, Fujian 361005, China
Spectrochim Acta A Mol Biomol Spectrosc 61:761-5. 2005..XPS and IR characterizations of the interaction between glucose and Au3+ further supported that the reduction of Au3+ to Au0 can directly occur at the aldehyde group of the reducing sugars...
Fabrication of well-defined PLGA scaffolds using novel microembossing and carbon dioxide bondingYong Yang
The Department of Chemical and Biomolecular Engineering, The Ohio State University, 140 West 19th Avenue, Columbus, OH 43210, USA
Biomaterials 26:2585-94. 2005....
Inverse treatment planning with adaptively evolving voxel-dependent penalty schemeYong Yang
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305-5847, USA
Med Phys 31:2839-44. 2004....
Effect of replacement of fish meal by meat and bone meal and poultry by-product meal in diets on the growth and immune response of Macrobrachium nipponenseYong Yang
State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, The Chinese Academy of Sciences, Wuhan, Hubei 430072, PR China
Fish Shellfish Immunol 17:105-14. 2004..In conclusion, either MBM or PBM investigated could replace up to 50% fish meal protein in diets for M. nipponense...
Inhibitory effects of antisense RNA of HAb18G/CD147 on invasion of hepatocellular carcinoma cells in vitroYu Li
Department of Cell Biology, Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China
World J Gastroenterol 9:2174-7. 2003..CONCLUSION: Invasion of HCC cells can be inhibited by antisense RNA of HAb18G/CD147. HAb18G/CD147 may be used as a potential target of drugs for anti-invasion and metastasis of HCC...
Using the volumetric effect of a finite-sized detector for routine quality assurance of multileaf collimator leaf positioningYong Yang
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305-5304, USA
Med Phys 30:433-41. 2003..The principle of our method is independent of the types of the MLC and the detector and may have significant practical implications in facilitating routine MLC QA for IMRT delivery...
Quantitative characterization of biomolecular assemblies and interactions using atomic force microscopyYong Yang
Department of Chemistry, University of North Carolina at Chapel Hill at Chapel Hill, Chapel Hill, NC 27599, USA
Methods 29:175-87. 2003..These developments make AFM a powerful tool for investigating the biomolecular assemblies and interactions that govern gene regulation...
Model-based image reconstruction for four-dimensional PETTianfang Li
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305-5847, USA
Med Phys 33:1288-98. 2006..Finally, the 4D PET reconstruction was applied to a patient case...
Increase in beta1-6 GlcNAc branching caused by N-acetylglucosaminyltransferase V directs integrin beta1 stability in human hepatocellular carcinoma cell line SMMC-7721Liying Wang
Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032, China
J Cell Biochem 100:230-41. 2007..Glycosylation caused by GnT-V directs integrin beta1 stability and more delivery to plasma membrane, subsequently promotes Fn-based cell migration and invasion...
New valve and bonding designs for microfluidic biochips containing proteinsChunmeng Lu
Department of Chemical and Biomolecular Engineering, Nanoscale Science and Engineering Center for Affordable Nanoengineering of Polymeric Biomedical Devices, The Ohio State University, Columbus, Ohio 43210, USA
Anal Chem 79:994-1001. 2007..This bonding method has little influence on the activity of the pre-loaded proteins after bonding...
Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7Chongyang Han
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China
Mol Pain 3:3. 2007..It has recently been shown that several disease-causing erythromelalgia mutations alter channel-gating behavior in a manner that increases DRG neuron excitability...
Increased expression of integrin beta1 subunit enhances p21WAF1/Cip1 transcription through the Sp1 sites and p300-mediated histone acetylation in human hepatocellular carcinoma cellsZhengyu Fang
Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, PR China
J Cell Biochem 101:654-64. 2007..Therefore, these findings presented the mechanisms by which integrin beta1 induced the elevated p21 expression in hepatic cancer cells...
Proline-rich tyrosine kinase2 is involved in F-actin organization during in vitro maturation of rat oocyteXiao Qian Meng
Key Laboratory of Animal Resistance, College of Life Science, Shandong Normal University, 88 East Wenhua Road, Jinan 250002, People s Republic of China
Reproduction 132:859-67. 2006..These findings suggest an important role of Pyk2 for rat oocyte maturation by regulating the organization of actin filaments...
Combination of integrin siRNA and irradiation for breast cancer therapyQizhen Cao
Molecular Imaging Program at Stanford and Bio-X, Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA
Biochem Biophys Res Commun 351:726-32. 2006..This study, with further optimization, may provide a simple and highly efficient treatment strategy for breast cancer as well as other integrin alpha(v)beta(3)-positive cancer types...
Oroxylin A induced apoptosis of human hepatocellular carcinoma cell line HepG2 was involved in its antitumor activityYang Hu
Department of Physiology, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China
Biochem Biophys Res Commun 351:521-7. 2006..These results demonstrated that oroxylin A could effectively induce programmed cell death and suggested that it could be a promising antitumor drug...
Profilin 1 obtained by proteomic analysis in all-trans retinoic acid-treated hepatocarcinoma cell lines is involved in inhibition of cell proliferation and migrationNan Wu
Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, P R China
Proteomics 6:6095-106. 2006..Furthermore, RNAi-based PFN1 knockdown could rescue the inhibitory effect of ATRA on cell proliferation and migration. In conclusion, ATRA inhibited cell proliferation and migration through up-regulation of PFN1...
Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-beta1Wei Guo
Department of Nephrology, Children s Hospital of Fudan University, 183 Feng Lin Road, Shanghai, 200032, P R China
Mol Cell Biochem 295:167-77. 2007..Therefore, over-expression of PHB suppresses renal interstitial fibroblasts proliferation and cell phenotypic change induced by TGF-beta1, which indicates PHB as a potential therapeutic target to halt the progression of TIF...
Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cellsJun Yu
Department of Physiology, China Pharmaceutical University, Nanjing 210009, People s Republic of China
Carcinogenesis 28:632-8. 2007..The reduced CDK7 kinase activity is responsible for the inactivation of CDC2/p34 kinase and the irreversible G(2)/M phase cell-cycle arrest of human gastric carcinoma BGC-823 cells...
Requirements of Src family kinase during meiotic maturation in mouse oocyteKe Gang Zheng
Key Laboratory of Biology of Animal Resistance, College of Life Science, Shandong Normal University, Jinan, China
Mol Reprod Dev 74:125-30. 2007..When the SFK activity was inhibited, the oocyte failed to initiate GVBD, could not go into MII, and could not extrude the first polar body. Our results demonstrated that SFK is required for meiotic maturation in mouse oocyte...
Involvement of bax/bcl-2 in wogonin-induced apoptosis of human hepatoma cell line SMMC-7721Wei Wang
Department of Physiology, China Pharmaceutical University, Nanjing, PRC
Anticancer Drugs 17:797-805. 2006....
A three-source model for the calculation of head scatter factorsYong Yang
Department of Radiation Oncology, Stanford University, California 94305 5304, USA
Med Phys 29:2024-33. 2002..4%. The algorithm can also be easily applied to deal with irregular fields shaped by a multileaf collimator that replaces the upper or lower collimator jaws...
