Yong Yang

Summary

Country: China

Publications

  1. ncbi request reprint Fourier-based analysis of moiré fringe patterns of superposed gratings in alignment of nanolithography
    Shaolin Zhou
    Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu 610209, China
    Opt Express 16:7869-80. 2008
  2. doi request reprint Multimodal optical microscopy in combination with gold nanorods for cancer cell imaging
    Cai Jun Cao
    Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Single Molecule Detection and Imaging Laboratory, Guangdong 518055, China
    J Biomed Opt 17:126002. 2012
  3. doi request reprint Extended dual-grating alignment method for optical projection lithography
    Wangfu Chen
    State Key Laboratory of Optical Technologies for Microfabrication, Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu 610209, China
    Appl Opt 49:708-13. 2010
  4. doi request reprint Tilt-modulated spatial phase imaging method for wafer-mask leveling in proximity lithography
    Shaolin Zhou
    State Key Laboratory of Optical Technologies for Microfabrication, Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu 610209, China
    Opt Lett 35:3132-4. 2010
  5. doi request reprint A low-temperature solid-phase method to synthesize highly fluorescent carbon nitride dots with tunable emission
    Juan Zhou
    Single Molecule Detection and Imaging Laboratory, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
    Chem Commun (Camb) 49:8605-7. 2013
  6. doi request reprint Simultaneous measurement of SUMOylation using SNAP/CLIP-tag-mediated translation at the single-molecule level
    Yong Yang
    Single Molecule Detection and Imaging Laboratory, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Guangdong, China
    Angew Chem Int Ed Engl 52:691-4. 2013
  7. ncbi request reprint N-glycosylation affects the adhesive function of E-Cadherin through modifying the composition of adherens junctions (AJs) in human breast carcinoma cell line MDA-MB-435
    Hongbo Zhao
    Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, PR China
    J Cell Biochem 104:162-75. 2008
  8. ncbi request reprint Localization of NGF and TrkA at mitotic apparatus in human glioma cell line U251
    Zhijian Zhang
    School of Medicine, Jiangsu University, Jiangsu Zhenjiang 212001, China
    Biochem Biophys Res Commun 337:68-74. 2005
  9. ncbi request reprint Protein phosphatase activity of PTEN inhibited the invasion of glioma cells with epidermal growth factor receptor mutation type III expression
    Xiu mei Cai
    Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, China
    Int J Cancer 117:905-12. 2005
  10. ncbi request reprint Localization of phosphorylated TrkA in carrier vesicles involved in its nuclear translocation in U251 cell line
    Aihua Gong
    School of Medicine, Jiangsu University, Zhenjiang 212013, China
    Sci China C Life Sci 50:141-6. 2007

Collaborators

Detail Information

Publications58

  1. ncbi request reprint Fourier-based analysis of moiré fringe patterns of superposed gratings in alignment of nanolithography
    Shaolin Zhou
    Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu 610209, China
    Opt Express 16:7869-80. 2008
    ....
  2. doi request reprint Multimodal optical microscopy in combination with gold nanorods for cancer cell imaging
    Cai Jun Cao
    Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Single Molecule Detection and Imaging Laboratory, Guangdong 518055, China
    J Biomed Opt 17:126002. 2012
    ..This multimodal optical microscopy might provide a reliable and complementary approach for biological and biomedical research...
  3. doi request reprint Extended dual-grating alignment method for optical projection lithography
    Wangfu Chen
    State Key Laboratory of Optical Technologies for Microfabrication, Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu 610209, China
    Appl Opt 49:708-13. 2010
    ..Analytical results indicate that alignment is independent of the gap between wafer and mask, disturbance from the fluctuation in illumination can be neglected, and alignment resolution in subnanometers can be realized with this scheme...
  4. doi request reprint Tilt-modulated spatial phase imaging method for wafer-mask leveling in proximity lithography
    Shaolin Zhou
    State Key Laboratory of Optical Technologies for Microfabrication, Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu 610209, China
    Opt Lett 35:3132-4. 2010
    ..Finally, wafer-mask leveling can be achieved at only one spot with preserved accuracy. Computational and experimental results confirm that tilts at the magnitude of 10(-3) rad can be readily resolved by this method...
  5. doi request reprint A low-temperature solid-phase method to synthesize highly fluorescent carbon nitride dots with tunable emission
    Juan Zhou
    Single Molecule Detection and Imaging Laboratory, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
    Chem Commun (Camb) 49:8605-7. 2013
    ..Notably, the tunable emission of g-CNQDs can be achieved by simply adjusting the molar ratio of the two reactants. ..
  6. doi request reprint Simultaneous measurement of SUMOylation using SNAP/CLIP-tag-mediated translation at the single-molecule level
    Yong Yang
    Single Molecule Detection and Imaging Laboratory, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Guangdong, China
    Angew Chem Int Ed Engl 52:691-4. 2013
    ..This method gives exceptional sensitivity, and is capable of measuring the SUMOylation of different proteins under various physiological conditions...
  7. ncbi request reprint N-glycosylation affects the adhesive function of E-Cadherin through modifying the composition of adherens junctions (AJs) in human breast carcinoma cell line MDA-MB-435
    Hongbo Zhao
    Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, PR China
    J Cell Biochem 104:162-75. 2008
    ..These findings demonstrate that N-glycosylation may affect the adhesive function of E-cadherin through modifying the composition of AJs...
  8. ncbi request reprint Localization of NGF and TrkA at mitotic apparatus in human glioma cell line U251
    Zhijian Zhang
    School of Medicine, Jiangsu University, Jiangsu Zhenjiang 212001, China
    Biochem Biophys Res Commun 337:68-74. 2005
    ..The phosphorylated TrkA with the tyrosine kinase activity may phosphorylate the tubulin and promote the mitotic spindle assembly. By these mechanisms, NGF can modulate the mitosis of human glioma cells...
  9. ncbi request reprint Protein phosphatase activity of PTEN inhibited the invasion of glioma cells with epidermal growth factor receptor mutation type III expression
    Xiu mei Cai
    Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, China
    Int J Cancer 117:905-12. 2005
    ....
  10. ncbi request reprint Localization of phosphorylated TrkA in carrier vesicles involved in its nuclear translocation in U251 cell line
    Aihua Gong
    School of Medicine, Jiangsu University, Zhenjiang 212013, China
    Sci China C Life Sci 50:141-6. 2007
    ..Accordingly, our results suggested that such a series of membrane compartments might be involved in the pathway of nuclear translocation of the transmembrane receptor TrkA...
  11. ncbi request reprint [Purification of colorectal cancer-associated antigen by immuno-affinity chromatography]
    Yong Yang
    Department of Cell Biology, Fourth Military Medical University, Xi an 710032, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20:348-51. 2004
    ..To purify and characterize the colorectal cancer-associated antigen from cultured colorectal cancer cells...
  12. ncbi request reprint [Improvement on microwave technology of extracting polysaccharide from yacon leaves]
    Jing Wei Li
    Sichuan Agricultural University, Institute of Maize Research, Ya an 625014, China
    Zhong Yao Cai 30:1449-52. 2007
    ....
  13. ncbi request reprint [Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-beta1]
    Wei Guo
    Department of Nephrology, Children s Hospital of Fudan University, Shanghai 200032, China
    Zhonghua Yi Xue Za Zhi 87:1660-5. 2007
    ..To illuminate the possible role of Prohibitin (PHB) in tubulointerstitial fibrosis...
  14. ncbi request reprint Inhibition of glioblastoma growth and angiogenesis by gambogic acid: an in vitro and in vivo study
    Lei Qiang
    Department of Physiology, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, People s Republic of China
    Biochem Pharmacol 75:1083-92. 2008
    ..Collectively, the current data indicated that GA may be of potential use in treatment of glioblastoma by apoptotic induction and antiangiogenic effects...
  15. ncbi request reprint The catalyst-assisted synthesis of high quality CdS single-crystal nanowires through an epitaxy mechanism
    Zengtao Liu
    State Key Laboratory for Physical Chemistry of Solid Surface, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, PR China
    J Nanosci Nanotechnol 7:3152-6. 2007
    ..e., (0001)CdS // (111)Au, and [1210]CdS // [011]Au...
  16. ncbi request reprint Dynamics of nitric oxide and peroxynitrite during global brain ischemia/reperfusion in rat hippocampus: NO-sensor measurement and modeling study
    Yong Yang
    Department of Biomedical Engineering, Zhejiang University yuqun campus, Hangzhou, 310027, PR China
    Neurochem Res 33:73-80. 2008
    ..Results show the rate of NO formation has a great influence on peroxynitrite dynamics...
  17. ncbi request reprint Gambogic acid inhibits angiogenesis through suppressing vascular endothelial growth factor-induced tyrosine phosphorylation of KDR/Flk-1
    Na Lu
    Jiangsu Key Laboratory of Carcinogenesis and Intervention China Pharmaceutical University, Nanjing, PR China
    Cancer Lett 258:80-9. 2007
    ..Taken together, these findings strongly suggest that GA might be a structurally novel angiogenesis inhibitor...
  18. pmc A comparison of nLC-ESI-MS/MS and nLC-MALDI-MS/MS for GeLC-based protein identification and iTRAQ-based shotgun quantitative proteomics
    Yong Yang
    U S Plant, Soil and Nutrition Laboratory, Tower Road, Ithaca, NY 14853, USA
    J Biomol Tech 18:226-37. 2007
    ....
  19. ncbi request reprint Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes
    Yong Yang
    Department of Physiology, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China
    Cancer Lett 256:259-66. 2007
    ..So GA might be a kind of highly effective anticancer drug candidate with low toxicity to normal tissue...
  20. doi request reprint Posttranscriptional regulation of the telomerase hTERT by gambogic acid in human gastric carcinoma 823 cells
    Qing Zhao
    Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, People s Republic of China
    Cancer Lett 262:223-31. 2008
    ..Collectively, we suggest that GA represses telomerase activity not only by repressing hTERT transcriptional activity via c-Myc but also by posttranslational modification of hTERT via Akt...
  21. ncbi request reprint N-glycosylation at Asn residues 554 and 566 of E-cadherin affects cell cycle progression through extracellular signal-regulated protein kinase signaling pathway
    Hongbo Zhao
    Key Laboratory of Glycoconjugate Research, Ministry of Health, Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Acta Biochim Biophys Sin (Shanghai) 40:140-8. 2008
    ..These findings implied that N-glycosylation might be crucial for E-cadherin-mediated suppression of cell cycle progression...
  22. doi request reprint Single-molecule diffusion study of activated EGFR implicates its endocytic pathway
    Zeyu Xiao
    Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China
    Biochem Biophys Res Commun 369:730-4. 2008
    ..It provided supporting evidence for the occurrence of both clathrin-dependent and caveolae-dependent EGFR endocytosis...
  23. pmc Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore
    Yong Yang
    Hefei National Laboratory for Physical Sciences at Micro scale and University of Science and Technology of China, Hefei 230027, China
    J Biol Chem 283:26726-36. 2008
    ..Thus, we reason that HsMis13 phosphorylation by Aurora B is required for organizing a stable bi-oriented microtubule kinetochore attachment that is essential for faithful chromosome segregation in mitosis...
  24. doi request reprint Microtubule depolymerization and phosphorylation of c-Jun N-terminal kinase-1 and p38 were involved in gambogic acid induced cell cycle arrest and apoptosis in human breast carcinoma MCF-7 cells
    Jing Chen
    Jiangsu Key Laboratory of Carcinogenesis and Intervention China Pharmaceutical University, Nanjing, PR China
    Life Sci 83:103-9. 2008
    ..Taken together, our results suggested that GA depolymerized microtubules and elevated the phosphorylation levels of JNK1 and p38, which caused G2/M cell cycle arrest and apoptosis in MCF-7 cells...
  25. ncbi request reprint Fabrication of well-defined PLGA scaffolds using novel microembossing and carbon dioxide bonding
    Yong Yang
    The Department of Chemical and Biomolecular Engineering, The Ohio State University, 140 West 19th Avenue, Columbus, OH 43210, USA
    Biomaterials 26:2585-94. 2005
    ....
  26. doi request reprint Inhibition of alpha(4) integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with gambogic acid
    Jie Zhao
    Jiangsu Key Laboratory of Carcinogenesis and Intervention China Pharmaceutical University, Nanjing, PR China
    Eur J Pharmacol 589:127-31. 2008
    ..Thus we concluded for the first time that gambogic acid could inhibit the adhesion and migration of B16-F10 cells in vitro and in vivo, in which down-regulation of alpha(4) integrin expression was involved...
  27. doi request reprint Endostar suppresses invasion through downregulating the expression of matrix metalloproteinase-2/9 in MDA-MB-435 human breast cancer cells
    Na Lu
    Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 210009 Nanjing, People s Republic of China
    Exp Biol Med (Maywood) 233:1013-20. 2008
    ..Additionally, endostar exerted an inhibitory effect on the phosphorylation of ERK1/2. Collectively, these data provided a molecular basis for the anti-invasive effects of endostar...
  28. doi request reprint Biodegradable urethral stent in the treatment of post-traumatic urethral strictures in a war wound rabbit urethral model
    Wei Jun Fu
    Department of Urology, Chinese People s Liberation Army General Hospital, Military Postgraduate Medical College, No 28 Fuxing road, Hai Dian District, Beijing 100853, People s Republic of China
    Biomed Mater 2:263-8. 2007
    ..There are distinct advantages in terms of safe, effective and less-invasive treatment for the reconstruction of post-traumatic urethral strictures...
  29. doi request reprint Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2
    Na Lu
    Jiangsu Key Laboratory of Carcinogenesis and Intervention China Pharmaceutical University, Nanjing 210009, People s Republic of China
    Life Sci 82:956-63. 2008
    ..Taken together, these findings strongly suggest that wogonin might be a promising antitumor drug...
  30. doi request reprint Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression
    Kun Zhang
    Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, China
    Cancer Sci 99:689-95. 2008
    ..Taken together, the results reported here demonstrated that wogonin could promote the granulocytic differentiation of NB4 cells by up-regulating the expression of PLSCR1 gene...
  31. doi request reprint Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCdelta phosphorylation
    Hai Wei Zhang
    Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, China
    Eur J Pharmacol 591:7-12. 2008
    ..Taken together, wogonin induced U-937 cells to undergo granulocytic differentiation and G1 phase arrest via PKCdelta phosphorylation-induced upregulation of p21 proteins...
  32. ncbi request reprint Endostar, a novel recombinant human endostatin, exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cells
    Yun Ling
    Department of Physiology, China Pharmaceutical University, Nanjing 210009, China
    Biochem Biophys Res Commun 361:79-84. 2007
    ..Collectively, these data indicated the relationship between endostar and VEGF signal pathways and provided a molecular basis for the antiangiogenic effects of endostar...
  33. ncbi request reprint Overexpression of integrin beta1 inhibits proliferation of hepatocellular carcinoma cell SMMC-7721 through preventing Skp2-dependent degradation of p27 via PI3K pathway
    Yi Fu
    Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032, China
    J Cell Biochem 102:704-18. 2007
    ..Together, these results suggested that overexpression of integrin beta1 inhibited cell proliferation by preventing the Skp2-dependent degradation of p27(Kip1) via PI3K pathway...
  34. ncbi request reprint Model-based image reconstruction for four-dimensional PET
    Tianfang Li
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305 5847, USA
    Med Phys 33:1288-98. 2006
    ..Finally, the 4D PET reconstruction was applied to a patient case...
  35. ncbi request reprint The psoriasis disability index in Chinese patients: contribution of clinical and psychological variables
    Yong Yang
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore, and the National Skin Center, Singapore
    Int J Dermatol 44:925-9. 2005
    ..To provide a description of medical and psychological aspects of Chinese psoriasis patients, and to examine the specific contribution of demographic, medical and psychological variables to the Psoriasis Disability Index...
  36. ncbi request reprint Towards biologically conformal radiation therapy (BCRT): selective IMRT dose escalation under the guidance of spatial biology distribution
    Yong Yang
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305 5847, USA
    Med Phys 32:1473-84. 2005
    ..The proposed formalism lays a technical foundation for BCRT and allows us to maximally exploit the technical capacity of IMRT to more intelligently escalate the radiation dose...
  37. pmc Involvement of CD147 in overexpression of MMP-2 and MMP-9 and enhancement of invasive potential of PMA-differentiated THP-1
    Jun Zhou
    Department of Clinical Immunology, First Affiliated Hospital, Fourth Military Medical University, 17 Changlexilu, Xi an 710032, Shaanxi, P R China
    BMC Cell Biol 6:25. 2005
    ..We found in our study that CD147 played a very important role in this process...
  38. ncbi request reprint Template guided self-assembling two-dimensional array of Au@SiO2 core-shell nanoparticles for room-temperature single electron transistors
    Yong Yang
    Department of Materials Science and Engineering, Nagoya Institute of Technology, Showa, Nagoya 466 8555, Japan
    J Nanosci Nanotechnol 5:179-83. 2005
    ..The tunable single electron tunneling properties make the 2D array of Au@SiO2 composite nanoparticles an ideal candidate for planar single electron transistor devices...
  39. ncbi request reprint Spectroscopic characterization of Au3+ biosorption by waste biomass of Saccharomyces cerevisiae
    Zhongyu Lin
    State Key Laboratory for Physical Chemistry of Solid Surface, Department of Chemistry, Xiamen University, Xiamen, Fujian 361005, China
    Spectrochim Acta A Mol Biomol Spectrosc 61:761-5. 2005
    ..XPS and IR characterizations of the interaction between glucose and Au3+ further supported that the reduction of Au3+ to Au0 can directly occur at the aldehyde group of the reducing sugars...
  40. ncbi request reprint Inverse treatment planning with adaptively evolving voxel-dependent penalty scheme
    Yong Yang
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305 5847, USA
    Med Phys 31:2839-44. 2004
    ....
  41. ncbi request reprint Effect of replacement of fish meal by meat and bone meal and poultry by-product meal in diets on the growth and immune response of Macrobrachium nipponense
    Yong Yang
    State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, The Chinese Academy of Sciences, Wuhan, Hubei 430072, PR China
    Fish Shellfish Immunol 17:105-14. 2004
    ..In conclusion, either MBM or PBM investigated could replace up to 50% fish meal protein in diets for M. nipponense...
  42. ncbi request reprint Inhibitory effects of antisense RNA of HAb18G/CD147 on invasion of hepatocellular carcinoma cells in vitro
    Yu Li
    Department of Cell Biology, Fourth Military Medical University, Xi an 710032, Shaanxi Province, China
    World J Gastroenterol 9:2174-7. 2003
    ..To study the inhibitory effects of antisense RNA of HAb18G/CD147 on invasion of hepatocellular carcinoma(HCC) cells in vitro...
  43. ncbi request reprint Using the volumetric effect of a finite-sized detector for routine quality assurance of multileaf collimator leaf positioning
    Yong Yang
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305 5304, USA
    Med Phys 30:433-41. 2003
    ..The principle of our method is independent of the types of the MLC and the detector and may have significant practical implications in facilitating routine MLC QA for IMRT delivery...
  44. ncbi request reprint Quantitative characterization of biomolecular assemblies and interactions using atomic force microscopy
    Yong Yang
    Department of Chemistry, University of North Carolina at Chapel Hill at Chapel Hill, Chapel Hill, NC 27599, USA
    Methods 29:175-87. 2003
    ..These developments make AFM a powerful tool for investigating the biomolecular assemblies and interactions that govern gene regulation...
  45. ncbi request reprint Increase in beta1-6 GlcNAc branching caused by N-acetylglucosaminyltransferase V directs integrin beta1 stability in human hepatocellular carcinoma cell line SMMC-7721
    Liying Wang
    Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032, China
    J Cell Biochem 100:230-41. 2007
    ..Glycosylation caused by GnT-V directs integrin beta1 stability and more delivery to plasma membrane, subsequently promotes Fn-based cell migration and invasion...
  46. ncbi request reprint Involvement of bax/bcl-2 in wogonin-induced apoptosis of human hepatoma cell line SMMC-7721
    Wei Wang
    Department of Physiology, China Pharmaceutical University, Nanjing, PRC
    Anticancer Drugs 17:797-805. 2006
    ....
  47. ncbi request reprint Anti-hepatitis B virus activity of wogonin in vitro and in vivo
    Qinglong Guo
    Department of Physiology, China Pharmaceutical University, Nanjing, China
    Antiviral Res 74:16-24. 2007
    ..In conclusion, our results demonstrate that wogonin possesses potent anti-HBV activity both in vitro and in vivo. Currently, wogonin is under early development as an anti-HBV drug candidate...
  48. ncbi request reprint New valve and bonding designs for microfluidic biochips containing proteins
    Chunmeng Lu
    Department of Chemical and Biomolecular Engineering, Nanoscale Science and Engineering Center for Affordable Nanoengineering of Polymeric Biomedical Devices, The Ohio State University, Columbus, Ohio 43210, USA
    Anal Chem 79:994-1001. 2007
    ..This bonding method has little influence on the activity of the pre-loaded proteins after bonding...
  49. pmc Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7
    Chongyang Han
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China
    Mol Pain 3:3. 2007
    ..It has recently been shown that several disease-causing erythromelalgia mutations alter channel-gating behavior in a manner that increases DRG neuron excitability...
  50. ncbi request reprint Increased expression of integrin beta1 subunit enhances p21WAF1/Cip1 transcription through the Sp1 sites and p300-mediated histone acetylation in human hepatocellular carcinoma cells
    Zhengyu Fang
    Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, PR China
    J Cell Biochem 101:654-64. 2007
    ..Therefore, these findings presented the mechanisms by which integrin beta1 induced the elevated p21 expression in hepatic cancer cells...
  51. ncbi request reprint Proline-rich tyrosine kinase2 is involved in F-actin organization during in vitro maturation of rat oocyte
    Xiao Qian Meng
    Key Laboratory of Animal Resistance, College of Life Science, Shandong Normal University, 88 East Wenhua Road, Jinan 250002, People s Republic of China
    Reproduction 132:859-67. 2006
    ..These findings suggest an important role of Pyk2 for rat oocyte maturation by regulating the organization of actin filaments...
  52. ncbi request reprint Combination of integrin siRNA and irradiation for breast cancer therapy
    Qizhen Cao
    Molecular Imaging Program at Stanford and Bio X, Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Biochem Biophys Res Commun 351:726-32. 2006
    ..This study, with further optimization, may provide a simple and highly efficient treatment strategy for breast cancer as well as other integrin alpha(v)beta(3)-positive cancer types...
  53. ncbi request reprint Oroxylin A induced apoptosis of human hepatocellular carcinoma cell line HepG2 was involved in its antitumor activity
    Yang Hu
    Department of Physiology, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China
    Biochem Biophys Res Commun 351:521-7. 2006
    ..These results demonstrated that oroxylin A could effectively induce programmed cell death and suggested that it could be a promising antitumor drug...
  54. ncbi request reprint Profilin 1 obtained by proteomic analysis in all-trans retinoic acid-treated hepatocarcinoma cell lines is involved in inhibition of cell proliferation and migration
    Nan Wu
    Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, P R China
    Proteomics 6:6095-106. 2006
    ..Furthermore, RNAi-based PFN1 knockdown could rescue the inhibitory effect of ATRA on cell proliferation and migration. In conclusion, ATRA inhibited cell proliferation and migration through up-regulation of PFN1...
  55. ncbi request reprint Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-beta1
    Wei Guo
    Department of Nephrology, Children s Hospital of Fudan University, 183 Feng Lin Road, Shanghai, 200032, P R China
    Mol Cell Biochem 295:167-77. 2007
    ..Therefore, over-expression of PHB suppresses renal interstitial fibroblasts proliferation and cell phenotypic change induced by TGF-beta1, which indicates PHB as a potential therapeutic target to halt the progression of TIF...
  56. ncbi request reprint Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells
    Jun Yu
    Department of Physiology, China Pharmaceutical University, Nanjing 210009, People s Republic of China
    Carcinogenesis 28:632-8. 2007
    ..The reduced CDK7 kinase activity is responsible for the inactivation of CDC2/p34 kinase and the irreversible G(2)/M phase cell-cycle arrest of human gastric carcinoma BGC-823 cells...
  57. ncbi request reprint Requirements of Src family kinase during meiotic maturation in mouse oocyte
    Ke Gang Zheng
    Key Laboratory of Biology of Animal Resistance, College of Life Science, Shandong Normal University, Jinan, China
    Mol Reprod Dev 74:125-30. 2007
    ..When the SFK activity was inhibited, the oocyte failed to initiate GVBD, could not go into MII, and could not extrude the first polar body. Our results demonstrated that SFK is required for meiotic maturation in mouse oocyte...
  58. ncbi request reprint A three-source model for the calculation of head scatter factors
    Yong Yang
    Department of Radiation Oncology, Stanford University, California 94305 5304, USA
    Med Phys 29:2024-33. 2002
    ..4%. The algorithm can also be easily applied to deal with irregular fields shaped by a multileaf collimator that replaces the upper or lower collimator jaws...