Pei zeng Yang

Summary

Country: China

Publications

  1. ncbi request reprint [Recent advances in clinical and basic studies of uveitis in China in the last five years]
    Pei zeng Yang
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou 510060, China
    Zhonghua Yan Ke Za Zhi 41:743-7. 2005
  2. ncbi request reprint [Recent advances in uveitis studies in China]
    Pei zeng Yang
    Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, The First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China
    Zhonghua Yan Ke Za Zhi 46:924-9. 2010
  3. pmc Phenotypes, distribution, and morphological features of antigen-presenting cells in the murine cornea following intravitreal injection
    Qianli Meng
    Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat Sen University, Guangzhou, PR China
    Mol Vis 13:475-86. 2007
  4. pmc A penetrating ocular injury can affect the induction of anterior chamber-associated immune deviation
    Fang Lei
    Department of Ophthalmology, First Affiliated Hospital, Department of Microbiology and Immunology, Zheng Zhou University, Zhengzhou, Henan Province, China
    Mol Vis 14:327-33. 2008
  5. pmc Association between polymorphisms of FCRL3, a non-HLA gene, and Behçet's disease in a Chinese population with ophthalmic manifestations
    Ke Li
    First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China
    Mol Vis 14:2136-42. 2008
  6. pmc Increased expression of Foxp3 in splenic CD8+ T cells from mice with anterior chamber-associated immune deviation
    Liqiong Jiang
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Uveitis Study Center, Sun Yat Sen University, Guangzhou, China
    Mol Vis 13:968-74. 2007
  7. pmc Polymorphisms of FCRL3 in a Chinese population with Vogt-Koyanagi-Harada (VKH) syndrome
    Ke Li
    The First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China
    Mol Vis 15:955-61. 2009
  8. pmc Small ubiquitin-like modifier 4 (SUMO4) polymorphisms and Vogt-Koyanagi-Harada (VKH) syndrome in the Chinese Han population
    Shengping Hou
    The First Affiliated Hospital, Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing, PR China
    Mol Vis 14:2597-603. 2008
  9. pmc Upregulation of CD94 on CD8+T cells in anterior chamber-associated immune deviation
    Hao He
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangzhou, PR China
    BMC Immunol 9:53. 2008
  10. ncbi request reprint Clinical features of chinese patients with Behçet's disease
    Peizeng Yang
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou, China
    Ophthalmology 115:312-318.e4. 2008

Collaborators

Detail Information

Publications45

  1. ncbi request reprint [Recent advances in clinical and basic studies of uveitis in China in the last five years]
    Pei zeng Yang
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou 510060, China
    Zhonghua Yan Ke Za Zhi 41:743-7. 2005
    ..Furthermore, abuse of corticosteroids is still rather common. Therefore, it is necessary to popularize the modern knowledge of uveitis among Chinese ophthalmologists and to improve basic and clinical uveitis studies in China...
  2. ncbi request reprint [Recent advances in uveitis studies in China]
    Pei zeng Yang
    Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, The First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China
    Zhonghua Yan Ke Za Zhi 46:924-9. 2010
    ..These studies have greatly contributed to the understanding as well as the treatment of this disease...
  3. pmc Phenotypes, distribution, and morphological features of antigen-presenting cells in the murine cornea following intravitreal injection
    Qianli Meng
    Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat Sen University, Guangzhou, PR China
    Mol Vis 13:475-86. 2007
    ..To study the phenotypes, distribution, and morphologies of different antigen-presenting cells (APCs) in the murine cornea...
  4. pmc A penetrating ocular injury can affect the induction of anterior chamber-associated immune deviation
    Fang Lei
    Department of Ophthalmology, First Affiliated Hospital, Department of Microbiology and Immunology, Zheng Zhou University, Zhengzhou, Henan Province, China
    Mol Vis 14:327-33. 2008
    ..To determine the effect of penetrating ocular injury on the induction of anterior chamber-associated immune deviation (ACAID)...
  5. pmc Association between polymorphisms of FCRL3, a non-HLA gene, and Behçet's disease in a Chinese population with ophthalmic manifestations
    Ke Li
    First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China
    Mol Vis 14:2136-42. 2008
    ..This study was designed to determine whether the polymorphisms of FCRL3 were associated with susceptibility to BD in a Chinese population mainly with ocular involvement...
  6. pmc Increased expression of Foxp3 in splenic CD8+ T cells from mice with anterior chamber-associated immune deviation
    Liqiong Jiang
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Uveitis Study Center, Sun Yat Sen University, Guangzhou, China
    Mol Vis 13:968-74. 2007
    ..To examine the expression of Foxp3 on CD8+ T cells in the spleen during anterior chamber-associated immune deviation (ACAID)...
  7. pmc Polymorphisms of FCRL3 in a Chinese population with Vogt-Koyanagi-Harada (VKH) syndrome
    Ke Li
    The First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China
    Mol Vis 15:955-61. 2009
    ..This study was designed to examine whether the polymorphisms of FCRL3 are associated with susceptibility to Vogt-Koyanagi-Harada (VKH) syndrome in a Chinese population...
  8. pmc Small ubiquitin-like modifier 4 (SUMO4) polymorphisms and Vogt-Koyanagi-Harada (VKH) syndrome in the Chinese Han population
    Shengping Hou
    The First Affiliated Hospital, Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing, PR China
    Mol Vis 14:2597-603. 2008
    ..To examine whether small ubiquitin-like modifier 4 (SUMO4) polymorphisms were associated with Vogt-Koyanagi-Harada (VKH) syndrome in the Chinese Han population...
  9. pmc Upregulation of CD94 on CD8+T cells in anterior chamber-associated immune deviation
    Hao He
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangzhou, PR China
    BMC Immunol 9:53. 2008
    ..Recent studies have reported that the CD94-Qa-1 system is implicated in the induction of ACAID CD8+Treg, but the functions and characteristics of CD8+CD94+T cells remain unclear...
  10. ncbi request reprint Clinical features of chinese patients with Behçet's disease
    Peizeng Yang
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou, China
    Ophthalmology 115:312-318.e4. 2008
    ..To characterize the clinical features of Behçet's disease in Chinese patients...
  11. ncbi request reprint Clinical features of Chinese patients with Fuchs' syndrome
    Peizeng Yang
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou, China
    Ophthalmology 113:473-80. 2006
    ..To characterize the clinical features of Chinese patients with Fuchs' syndrome...
  12. ncbi request reprint [Clinical diagnosis and treatment of uveitis associated with ankylosing spondylitis]
    Pei zeng Yang
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou 510060, China
    Zhonghua Yan Ke Za Zhi 41:515-8. 2005
    ..To investigate the clinical features, diagnosis, treatment and prognosis of uveitis associated with ankylosing spondylitis (AS)...
  13. doi request reprint Longitudinal study of anterior segment inflammation by ultrasound biomicroscopy in patients with acute anterior uveitis
    Yang Peizeng
    Zhongshan Ophthalmic Centre, Sun Yat Sen University, Guangzhou, Guangdong, China
    Acta Ophthalmol 87:211-5. 2009
    ..This study aimed to investigate dynamic changes in the anterior segment in patients with acute anterior uveitis (AAU) using ultrasound biomicroscopy (UBM)...
  14. ncbi request reprint Clinical characteristics of Vogt-Koyanagi-Harada syndrome in Chinese patients
    Peizeng Yang
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou, China
    Ophthalmology 114:606-14. 2007
    ..To characterize the clinical features of Vogt-Koyanagi-Harada syndrome (VKH) in Chinese patients...
  15. ncbi request reprint Study of macular function by multifocal electroretinography in patients with Vogt-Koyanagi-Harada syndrome
    Peizeng Yang
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Uveitis Study Center of Sun Yat sen University and International Uveitis Study Laboratory of Guangdong Province, Guangzhou, People s Republic of China
    Am J Ophthalmol 146:767-71. 2008
    ..We longitudinally investigated macular function by multifocal electroretinography (mfERG) in a cohort of patients with Vogt-Koyanagi-Harada (VKH) syndrome...
  16. ncbi request reprint [Advances in uveitis study]
    Pei zeng Yang
    Uveitis Study Center, Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou 510060, China
    Zhonghua Yan Ke Za Zhi 41:1149-52. 2005
    ..Novel techniques for uveitis diagnosis and the application of immunoregulatory and biologic agents have improved the treatment for the uveitis patients...
  17. doi request reprint Vogt-koyanagi-harada syndrome
    Wang Fang
    The First Affiliated Hospital of Chongqing Medical University, Chongqing, P R China
    Curr Eye Res 33:517-23. 2008
    ..It is also one of the most common forms of uveitis among pigmented races including Chinese patients...
  18. ncbi request reprint GATA-3 expression in the development of anterior chamber associated immune deviation
    Tao Fu
    Uveitis Study Center, Sun Yat Sen University, Guangzhou 510060, China
    Chin Med J (Engl) 118:2000-4. 2005
    ..GATA-3 has been shown to be necessary for the activation of Th2 cells. This study was designed to examine the expression of GATA-3 in the development of ACAID...
  19. ncbi request reprint Role of T-cell receptor V beta 8.3 peptide vaccine in the prevention of experimental autoimmune uveoretinitis
    Rui Zhang
    Zhongshan Ophthalmic Centre, Sun Yat Sen University, Guangzhou 510060, China
    Chin Med J (Engl) 119:740-8. 2006
    ..The aim of this study was to investigate whether vaccination with a synthetic peptide from the hypervariable region of TCR V(beta) 8.3, an experimental autoimmune uveoretinitis (EAU)-associated gene, was able to prevent the disease...
  20. ncbi request reprint [The clinical feature, diagnosis and treatment of uveitis associated with juvenile chronic arthritis]
    Zhen Zhang
    Zhongshan Ophthalmic Center, Zhongshan University, Guangzhou 510060, China
    Zhonghua Yan Ke Za Zhi 41:346-9. 2005
    ..To investigate the clinical features, diagnosis and treatment of uveitis associated with juvenile chronic arthritis (JCA)...
  21. ncbi request reprint [Evaluation of the problems in the treatment of uveitis]
    Pei zeng Yang
    Zhongshan Ophthalmic Center, Sun Yat Sen University of Medical Sciences, Guangzhou 510060, China
    Zhonghua Yan Ke Za Zhi 40:679-82. 2004
    ..To address the problems present in the treatment of uveitis...
  22. ncbi request reprint [Increased expression of Fas and FasL mRNA in peripheral blood lymphocytes in Vogt-Koyanagi-Harada syndrome]
    Ling Chen
    Zhongshan Ophthalmic Center, Sun Yat sen University of Medical Science, Guangzhou 510060, China
    Zhonghua Yan Ke Za Zhi 40:507-9. 2004
    ..To evaluate the expression of Fas and FasL messenger RNA (mRNA) in peripheral blood lymphocytes and its possible role in the pathogenesis of Vogt-Koyanagi-Harada syndrome...
  23. ncbi request reprint [Quantitative determination of aqueous flare and cells in the eyes of patients with inflammation of anterior uvea]
    Pei zeng Yang
    Zhongshan Ophthalmic Center, Zhongshan University, Guangzhou 510060, China
    Zhonghua Yan Ke Za Zhi 40:510-3. 2004
    ..To quantify aqueous flare and cells in the eyes of patients with inflammation of anterior uvea by FC-2000 laser flare cell meter (LFCM), and to compare these results with those obtained with slit lamp microscopy...
  24. ncbi request reprint [Expression of programmed death 1 and its ligands in iris-ciliary body from mice with anterior chamber-associated immune deviation]
    Qian Li Meng
    Zhongshan Ophthalmic Center, Uveitis Study Center, State Key Laboratory of Ophthalmology, Sun Yat Sen University, Guangzhou 510060, China
    Zhonghua Yan Ke Za Zhi 44:558-62. 2008
    ..To study the expression and possible implication of programmed death 1 (PD-1) and its ligands in the iris-ciliary body from mice with anterior chamber-associated immune deviation (ACAID)...
  25. ncbi request reprint [Studies on autoantigenic epitopes involving in the development of uveitis]
    Chang Lin Zhao
    International Uveitis Study Laboratory of Guangdong Province, Uveitis Study Center of Sun Yat sen University, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou 510060, China
    Zhonghua Yan Ke Za Zhi 44:377-80. 2008
    ..Study on this epitope spreading may contribute to our understanding of immune tolerance induced by different epitopes in the treatment of autoimmune disease including uveitis...
  26. ncbi request reprint [Fundus fluorescein and indocyanine green angiographic study of Behcet's disease and Vogt-Koyanagi-Harada syndrome]
    Ling Chen
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou 510060, China
    Zhonghua Yan Ke Za Zhi 38:210-2. 2002
    ..To study the choroidal and retinal changes in Behcet's disease and Vogt-Koyanagi-Harada syndrome (VKHS) using indocyanine green angiography (ICGA) and fundus fluorescein angiography (FFA)...
  27. ncbi request reprint [Therapeutic regimen in Vogt-Koyanagi-Harada syndrome]
    Peizeng Yang
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou 510060, China Email
    Zhonghua Yan Ke Za Zhi 38:196-9. 2002
    ..To compare the effectiveness of therapeutic regimen in Vogt-Koyanagi-Harada (VKH) syndrome and determine the reasonable regimen for different patients...
  28. ncbi request reprint Clinical patterns and characteristics of uveitis in a tertiary center for uveitis in China
    Peizeng Yang
    Uveitis Study Center, Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou, People s Republic of China
    Curr Eye Res 30:943-8. 2005
    ..To address the clinical pattern and characteristics of uveitis in a tertiary center for uveitis in China and compare the similarity and difference in the distribution of uveitis entities between China and other countries...
  29. doi request reprint MALDI-TOF/TOF-MS reveals elevated serum haptoglobin and amyloid A in Behcet's disease
    Liming Mao
    Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology of Sun Yat sen University, Guangzhou, P R China
    J Proteome Res 7:4500-7. 2008
    ..0% of the tested normal samples and 9.1% of VKH samples. Our results revealed a significantly increased expression of Hp and SAA in serum of active BD patients. These two proteins may be involved in the development of BD...
  30. ncbi request reprint [Clinical manifestations and diagnosis of Vogt-Koyanagi-Harada syndrome]
    Peizeng Yang
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou 510060, China
    Zhonghua Yan Ke Za Zhi 38:736-9. 2002
    ..To investigate the clinical features, causes of blindness and diagnosis of Vogt-Koyanagi-Harada (VKH) syndrome...
  31. pmc S-antigen specific T helper type 1 response is present in Behcet's disease
    Changlin Zhao
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou, PR China
    Mol Vis 14:1456-64. 2008
    ..To investigate the frequency and phenotypic and functional characteristics of S-antigen (S-Ag) specific T cells in patients with Behcet's disease (BD)...
  32. doi request reprint SUMO4 gene polymorphisms in Chinese Han patients with Behcet's disease
    Shengping Hou
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou, PR China
    Clin Immunol 129:170-5. 2008
    ..The GGAC haplotype is protectively associated with BD in HLA-B51 positive patients...
  33. doi request reprint Upregulated IL-23 and IL-17 in Behçet patients with active uveitis
    Wei Chi
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou, People s Republic of China
    Invest Ophthalmol Vis Sci 49:3058-64. 2008
    ..The interleukin (IL)-23/IL-17 pathway has been demonstrated to be involved in the development and maintenance of certain inflammatory diseases. This study was designed to investigate the role of IL-23 and IL-17 in BD...
  34. ncbi request reprint Resistance of lymphocytes to Fas-mediated apoptosis in Behçet's disease and Vogt-Koyangi-Harada syndrome
    Peizeng Yang
    Zhongshan Ophthalmic Center, Zhongshan University, Guangzhou, P R China
    Ocul Immunol Inflamm 10:47-52. 2002
    ..To investigate this hypothesis, a study was carried out to evaluate the resistance of lymphocytes to apoptosis in these two uveitis entities...
  35. ncbi request reprint Visualization of cell death in vivo during murine endotoxin-induced uveitis
    Peizeng Yang
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou, People s Republic of China
    Invest Ophthalmol Vis Sci 44:1993-7. 2003
    ....
  36. ncbi request reprint [Urea soluble fraction of bovine melanin associated antigen and experimental study on its uveitogenic activity]
    Zongyin Gao
    Zhongshan Ophthalmic Center, San Yat sen University, Guangzhou 510060, China Email
    Zhonghua Yan Ke Za Zhi 38:168-71. 2002
    ..The purpose of this study was to investigate the uveitogenic activity of autoantigen in the bovine iris-ciliary body...
  37. ncbi request reprint Inducible co-stimulator (ICOS) is upregulated in experimental autoimmune uveoretinitis
    Lin Xing
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Xianlie Road 54, Guangzhou, 510060, People s Republic of China
    Graefes Arch Clin Exp Ophthalmol 244:1650-8. 2006
    ..To study the expression of inducible co-stimulator (ICOS) and its association with T cell effector function in experimental autoimmune uveoretinitis (EAU)...
  38. ncbi request reprint Expression of Tim-3 is transiently increased before development of anterior chamber-associated immune deviation
    Yuqin Wang
    Uveitis Study Center, Key Laboratory of Ophthalmology, Sun Yat Sen University, Ministry of Education, Zhongshan Ophthalmic Center, Guangzhou, China
    Ocul Immunol Inflamm 14:151-6. 2006
    ..To assess the expression of T-cell immunoglobulin- and mucin-domain-containing molecule 3 (Tim-3) in the spleens of BALB/c mice undergoing anterior chamber-associated immune deviation (ACAID)...
  39. ncbi request reprint T-bet expression in the iris and spleen parallels disease expression during endotoxin-induced uveitis
    Bing Li
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou, 510060, People s Republic of China
    Graefes Arch Clin Exp Ophthalmol 245:407-13. 2007
    ..The aim of this study was to investigate kinetics of T-bet expression at the mRNA and protein levels during EIU using real-time PCR and whole-mount immunohistochemistry...
  40. ncbi request reprint CD4+PD-1+ T cells acting as regulatory cells during the induction of anterior chamber-associated immune deviation
    Qianli Meng
    Zhongshan Ophthalmic Center, Uveitis Study Center, Sun Yat Sen University, Key Laboratory of Ophthalmology, Ministry of Education, Guangzhou, People s Republic of China
    Invest Ophthalmol Vis Sci 47:4444-52. 2006
    ..To study the expression and functional characteristics of programmed death-1 (PD-1) and its ligands in the spleens of mice undergoing anterior chamber-associated immune deviation (ACAID)...
  41. ncbi request reprint IL-23 promotes CD4+ T cells to produce IL-17 in Vogt-Koyanagi-Harada disease
    Wei Chi
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Uveitis Study Center, Sun Yat Sen University, Guanzhou, China
    J Allergy Clin Immunol 119:1218-24. 2007
    ..Vogt-Koyanagi-Harada (VKH) disease is a systemic refractory autoimmune disease. IL-23 has been thought to play a critical role in autoimmune disease through inducing the development of IL-17-producing CD4(+) T cells...
  42. ncbi request reprint OVA-specific CD8+ T cells do not express granzyme B during anterior chamber associated immune deviation
    Yalin Ren
    Zhongshan Ophthalmic Center, Uveitis Study Center, Sun Yat Sen University, Key Laboratory of Ophthalmology, Ministry of Education, Guangzhou, People s Republic of China
    Graefes Arch Clin Exp Ophthalmol 244:1315-21. 2006
    ..To examine antigen (Ag)-specific CTL response during anterior chamber associated immune deviation (ACAID)...
  43. doi request reprint Association of the CTLA-4 gene with Vogt-Koyanagi-Harada syndrome
    Liping Du
    State Key Laboratory of Ophthalmology, Sun Yat Sen University, Guangzhou, PR China
    Clin Immunol 127:43-8. 2008
    ..1% versus 60.0%, P= 0.0013, n= 16, Pc = 0.021). These results suggest that CTLA-4 genetic polymorphisms are associated with the susceptibility to VKH syndrome...
  44. doi request reprint Diminished frequency and function of CD4+CD25high regulatory T cells associated with active uveitis in Vogt-Koyanagi-Harada syndrome
    Lina Chen
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Uveitis Study Center of Sun Yat sen University, Guangzhou, People s Republic of China
    Invest Ophthalmol Vis Sci 49:3475-82. 2008
    ..Vogt-Koyanagi-Harada (VKH) syndrome is an organ-specific autoimmune disease. This study was designed to phenotypically and functionally characterize peripheral blood CD4(+)CD25(high) Treg cells in VKH patients with active uveitis...
  45. ncbi request reprint Distribution, markers, and functions of retinal microglia
    Ling Chen
    Zhongshan Ophthalmic Center, Sun Yat Sen University of Medical Sciences, Guangzhou, P R China
    Ocul Immunol Inflamm 10:27-39. 2002
    ..The goal of this article was to review the present knowledge about retinal microglia and the function of retinal microglia in pathological conditions...