Jing jing Yang
Tao H, Yang J, Chen Z, Xu S, Zhou X, Zhan H, et al
. DNMT3A silencing RASSF1A promotes cardiac fibrosis through upregulation of ERK1/2. Toxicology. 2014;323:42-50 pubmed publisher
..Our results have shown that DNMT3A likely plays an essential role in RASSF1A mediated upregulation of ERK1/2 in rat cardiac fibrosis. DNMT3A and RASSF1A may serve as a new mechanism for cardiac fibrosis. ..
Tao H, Shi K, Yang J, Li J. Epigenetic mechanisms in atrial fibrillation: New insights and future directions. Trends Cardiovasc Med. 2016;26:306-18 pubmed publisher
..Further studies are needed to reveal the potential targets of epigenetic mechanisms, and it can be developed as a therapeutic target for AF. ..
Tao H, Yang J, Shi K, Li J. Wnt signaling pathway in cardiac fibrosis: New insights and directions. Metabolism. 2016;65:30-40 pubmed publisher
..It seems reasonable to suggest the potential targets of Wnt signaling pathway and it can be developed as a therapeutic target for cardiac fibrosis. ..
Tao H, Yang J, Shi K, Li J. Epigenetic factors MeCP2 and HDAC6 control Î±-tubulin acetylation in cardiac fibroblast proliferation and fibrosis. Inflamm Res. 2016;65:415-26 pubmed publisher
..This study indicated that MeCP2 could be a potentially new therapeutic option for cardiac fibrosis. ..