Huimin Yan

Summary

Country: China

Publications

  1. pmc Unpolarized release of vaccinia virus and HIV antigen by colchicine treatment enhances intranasal HIV antigen expression and mucosal humoral responses
    Yan Zhang
    Mucosal Immunity Research Group, The State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    PLoS ONE 6:e24296. 2011
  2. pmc Compromised NK cell-mediated antibody-dependent cellular cytotoxicity in chronic SIV/SHIV infection
    Xuan He
    Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    PLoS ONE 8:e56309. 2013
  3. doi request reprint Salivary IgA enhancement strategy for development of a nasal-spray anti-caries mucosal vaccine
    Huimin Yan
    Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
    Sci China Life Sci 56:406-13. 2013
  4. pmc Anti-HIV-1 activity of a new scorpion venom peptide derivative Kn2-7
    Yaoqing Chen
    State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, People s Republic of China
    PLoS ONE 7:e34947. 2012
  5. pmc Matrix protein-specific IgA antibody inhibits measles virus replication by intracellular neutralization
    Dihan Zhou
    Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
    J Virol 85:11090-7. 2011
  6. doi request reprint Recombinant flagellins with partial deletions of the hypervariable domain lose antigenicity but not mucosal adjuvancy
    Fang Liu
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, People s Republic of China
    Biochem Biophys Res Commun 392:582-7. 2010
  7. pmc L-selectin and P-selectin are novel biomarkers of cervicovaginal inflammation for preclinical mucosal safety assessment of anti-HIV-1 microbicide
    MaoHua Zhong
    Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    Antimicrob Agents Chemother 56:3121-32. 2012
  8. doi request reprint Flagellins of Salmonella Typhi and nonpathogenic Escherichia coli are differentially recognized through the NLRC4 pathway in macrophages
    Jingyi Yang
    Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    J Innate Immun 6:47-57. 2014
  9. doi request reprint Virucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses
    Qiaoli Li
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, People s Republic of China
    Peptides 32:1518-25. 2011
  10. pmc Monoclonal antibody that blocks the Toll-like receptor 5 binding region of flagellin
    Yaoming Li
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, People s Republic of China
    Hybridoma (Larchmt) 31:60-2. 2012

Collaborators

Detail Information

Publications12

  1. pmc Unpolarized release of vaccinia virus and HIV antigen by colchicine treatment enhances intranasal HIV antigen expression and mucosal humoral responses
    Yan Zhang
    Mucosal Immunity Research Group, The State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    PLoS ONE 6:e24296. 2011
    ..This conclusion can be used to optimize mucosal HIV vaccine strategies...
  2. pmc Compromised NK cell-mediated antibody-dependent cellular cytotoxicity in chronic SIV/SHIV infection
    Xuan He
    Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    PLoS ONE 8:e56309. 2013
    ....
  3. doi request reprint Salivary IgA enhancement strategy for development of a nasal-spray anti-caries mucosal vaccine
    Huimin Yan
    Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
    Sci China Life Sci 56:406-13. 2013
    ....
  4. pmc Anti-HIV-1 activity of a new scorpion venom peptide derivative Kn2-7
    Yaoqing Chen
    State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, People s Republic of China
    PLoS ONE 7:e34947. 2012
    ..These results demonstrated that peptide Kn2-7 could inhibit HIV-1 by direct interaction with viral particle and may become a promising candidate compound for further development of microbicide against HIV-1...
  5. pmc Matrix protein-specific IgA antibody inhibits measles virus replication by intracellular neutralization
    Dihan Zhou
    Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
    J Virol 85:11090-7. 2011
    ....
  6. doi request reprint Recombinant flagellins with partial deletions of the hypervariable domain lose antigenicity but not mucosal adjuvancy
    Fang Liu
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, People s Republic of China
    Biochem Biophys Res Commun 392:582-7. 2010
    ..Our data supported the notion that the hypervariable domain was involved in the cytokine production by flagellin and more importantly demonstrated that the hypervariable domain was important for the mucosal adjuvancy of flagellin...
  7. pmc L-selectin and P-selectin are novel biomarkers of cervicovaginal inflammation for preclinical mucosal safety assessment of anti-HIV-1 microbicide
    MaoHua Zhong
    Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    Antimicrob Agents Chemother 56:3121-32. 2012
    ....
  8. doi request reprint Flagellins of Salmonella Typhi and nonpathogenic Escherichia coli are differentially recognized through the NLRC4 pathway in macrophages
    Jingyi Yang
    Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    J Innate Immun 6:47-57. 2014
    ..Our findings suggest an active role of flagellin as an important determinant in host differential immune recognition and for the control of bacteria infection. ..
  9. doi request reprint Virucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses
    Qiaoli Li
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, People s Republic of China
    Peptides 32:1518-25. 2011
    ....
  10. pmc Monoclonal antibody that blocks the Toll-like receptor 5 binding region of flagellin
    Yaoming Li
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, People s Republic of China
    Hybridoma (Larchmt) 31:60-2. 2012
    ..Furthermore, this MAb would be useful for cytosolic localization of flagellin and would facilitate the elucidation of the physiological function of specific pathogen-associated molecular patterns...
  11. doi request reprint Effects of different immunization protocols and adjuvant on antibody responses to inactivated SARS-CoV vaccine
    Weiwei Gai
    The State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan University, Wuhan, China
    Viral Immunol 21:27-37. 2008
    ..Our study demonstrated that inactivated SARS-CoV vaccine is promising, and our data provide a sound foundation for the development of an effective inactivated SARS-CoV vaccine...
  12. ncbi request reprint SARS coronavirus induces apoptosis in Vero E6 cells
    Huimin Yan
    School of Life Sciences, Wuhan University, Wuhan, China
    J Med Virol 73:323-31. 2004
    ..This observation has some implications for the SARS-CoV pathogenicity: SARS-CoV does induce apoptosis in cell cultures and might have the same effect in vivo, responsible for the severe damage of the respiratory system...