Yan Xu

Summary

Country: China

Publications

  1. doi The application of gene co-expression network reconstruction based on CNVs and gene expression microarray data in breast cancer
    Yan Xu
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China
    Mol Biol Rep 39:1627-37. 2012
  2. pmc Prediction of human protein-protein interaction by a mixed Bayesian model and its application to exploring underlying cancer-related pathway crosstalk
    Yan Xu
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, People s Republic of China
    J R Soc Interface 8:555-67. 2011
  3. doi CNVD: text mining-based copy number variation in disease database
    Fujun Qiu
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China
    Hum Mutat 33:E2375-81. 2012
  4. doi Calculating phenotypic similarity between genes using hierarchical structure data based on semantic similarity
    Shanzhen Zhang
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, PR China
    Gene 497:58-65. 2012
  5. pmc Functional analysis of microRNA and transcription factor synergistic regulatory network based on identifying regulatory motifs in non-small cell lung cancer
    Kening Li
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China
    BMC Syst Biol 7:122. 2013
  6. pmc In vitro activity of thimerosal against ocular pathogenic fungi
    Yan Xu
    Department of Ocular Pharmacology, Henan Eye Institute, 7 Weiwu Road, Zhengzhou 450003, China
    Antimicrob Agents Chemother 54:536-9. 2010
  7. ncbi Ultrasound-mediated microbubble delivery of pigment epithelium-derived factor gene into retina inhibits choroidal neovascularization
    Xi Yuan Zhou
    Department of Ophthalmology, Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing, China
    Chin Med J (Engl) 122:2711-7. 2009
  8. ncbi [Comparison of the activities of silver nitrate with those of three antifungal agents against ocular pathogenic fungi in vitro]
    Yan Xu
    Henan Eye Institute, Zhengzhou 450003, China
    Zhonghua Yan Ke Za Zhi 45:730-5. 2009
  9. ncbi [Island sternocleidomastoid myocutaneous flap for repairing the buccal composite tissue defect]
    Tian Lan Zhao
    Department of Plastic and Aesthetic Surgery, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China
    Zhonghua Zheng Xing Wai Ke Za Zhi 25:337-9. 2009
  10. doi Integration of newly isolated biocatalyst and resin-based in situ product removal technique for the asymmetric synthesis of (R)-methyl mandelate
    Jin ling Guo
    Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, 214122 Wuxi, Jiangsu, China
    Bioprocess Biosyst Eng 33:797-804. 2010

Collaborators

Detail Information

Publications31

  1. doi The application of gene co-expression network reconstruction based on CNVs and gene expression microarray data in breast cancer
    Yan Xu
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China
    Mol Biol Rep 39:1627-37. 2012
    ....
  2. pmc Prediction of human protein-protein interaction by a mixed Bayesian model and its application to exploring underlying cancer-related pathway crosstalk
    Yan Xu
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, People s Republic of China
    J R Soc Interface 8:555-67. 2011
    ..Most of the pathways in top ranking clusters were shown to play important roles in cancer. The clusters themselves showed coherent function categories pertaining to cancer development...
  3. doi CNVD: text mining-based copy number variation in disease database
    Fujun Qiu
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China
    Hum Mutat 33:E2375-81. 2012
    ..The CNVD interface is accessible at http://bioinfo.hrbmu.edu.cn/CNVD...
  4. doi Calculating phenotypic similarity between genes using hierarchical structure data based on semantic similarity
    Shanzhen Zhang
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, PR China
    Gene 497:58-65. 2012
    ..Our study contributes to the development and optimization of novel algorithms of PSG calculation and provides more alternative methods to researchers as well as tools and directions for PSG study...
  5. pmc Functional analysis of microRNA and transcription factor synergistic regulatory network based on identifying regulatory motifs in non-small cell lung cancer
    Kening Li
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China
    BMC Syst Biol 7:122. 2013
    ..The patterns of their cooperation and biological functions in the synergistic regulatory network have rarely been studied...
  6. pmc In vitro activity of thimerosal against ocular pathogenic fungi
    Yan Xu
    Department of Ocular Pharmacology, Henan Eye Institute, 7 Weiwu Road, Zhengzhou 450003, China
    Antimicrob Agents Chemother 54:536-9. 2010
    ..Thimerosal's antifungal activity was significantly superior to those of amphotericin B and natamycin against ocular pathogenic fungi in vitro...
  7. ncbi Ultrasound-mediated microbubble delivery of pigment epithelium-derived factor gene into retina inhibits choroidal neovascularization
    Xi Yuan Zhou
    Department of Ophthalmology, Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing, China
    Chin Med J (Engl) 122:2711-7. 2009
    ....
  8. ncbi [Comparison of the activities of silver nitrate with those of three antifungal agents against ocular pathogenic fungi in vitro]
    Yan Xu
    Henan Eye Institute, Zhengzhou 450003, China
    Zhonghua Yan Ke Za Zhi 45:730-5. 2009
    ..To investigate antifungal activity of silver nitrate compared with fluconazole, ketoconazole and amphotericin B against ocular pathogenic fungi in vitro...
  9. ncbi [Island sternocleidomastoid myocutaneous flap for repairing the buccal composite tissue defect]
    Tian Lan Zhao
    Department of Plastic and Aesthetic Surgery, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China
    Zhonghua Zheng Xing Wai Ke Za Zhi 25:337-9. 2009
    ..To study the application of island sternocleidomastoid myocutaneous flap in repairing the buccal composite tissue defect especially penetrated tissue defect...
  10. doi Integration of newly isolated biocatalyst and resin-based in situ product removal technique for the asymmetric synthesis of (R)-methyl mandelate
    Jin ling Guo
    Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, 214122 Wuxi, Jiangsu, China
    Bioprocess Biosyst Eng 33:797-804. 2010
    ..The integration of newly isolated biocatalyst and proper ISPR technique provides a practical route for the preparation of optically active pharmaceutical intermediates...
  11. ncbi [Validation of Differential Extraction Kit in forensic sexual assault cases]
    Dan Wu
    Key Laboratory of Forensic Evidence and Scene Technology, Shanghai Key Laboratory of Crime Scene Evidence, Public Security Bureau of Shanghai, Shanghai 200083, China
    Fa Yi Xue Za Zhi 25:440-2. 2009
    ..To evaluate the validity of Differential Extraction Kit in isolating spermatozoa and epithelial cell DNA from mixture samples...
  12. ncbi [Gene cloning and expression of a novel (S)-specific carbonyl reductase]
    Yawei Geng
    Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China
    Wei Sheng Wu Xue Bao 50:60-6. 2010
    ..A novel (S)-specific carbonyl reductase gene (scr II) was cloned from the genome of Candida parapsilosis CCTCC M203011, and its catalytic function for the biotransformation of chiral alcohol was verified...
  13. ncbi [Activity of butenafine against ocular pathogenic filamentous fungi in vitro]
    Yan Xu
    Henan Eye Institute, Zhengzhou 450003, China
    Zhonghua Yan Ke Za Zhi 46:38-42. 2010
    ..To investigate antifungal activity of butenafine in comparison with that of natamycin, amphotericin B and fluconazole against ocular pathogenic filamentous fungi in vitro...
  14. ncbi [Experimental study on the relationship between the ratio of length to width of slender narrow pedicle and random flap survival area in pig]
    Tian Lan Zhao
    Department of Plastic and Cosmetic Surgery, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China
    Zhonghua Zheng Xing Wai Ke Za Zhi 27:40-3. 2011
    ..To explore the relationship between the ratio of length to width of slender narrow pedicle and random flap survival area, and to provide a theoretical basis for the clinical application of slender narrow pedicle flaps...
  15. ncbi Activation of peroxisome proliferator-activated receptor-gamma induces apoptosis on acute promyelocytic leukemia cells via downregulation of XIAP
    Jia Jun Liu
    Department of Hematology, The Third Hospital of Sun Yat Sen University, Guangzhou, 510630, PR China
    Int J Mol Med 24:623-32. 2009
    ..These data provide a novel insight into potential therapeutic strategies for treatment of leukemia...
  16. ncbi [Construction of an enzyme-coupled system consisting of (R)- and (S)-specific carbonyl reductases for one-step preparation of (S)-1-phenyl-1,2-ethanediol]
    Rongzhen Zhang
    Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China
    Wei Sheng Wu Xue Bao 49:204-9. 2009
    ..To prepare (S)-1-phenyl-1,2-ethanediol by a one-step method, we constructed an enzyme coupled system consisting of (R)- and (S)-specific carbonyl reductases in Escherichia coli...
  17. ncbi [Co-expression of formate dehydrogenase from Candida boidinii and (R)-specific carbonyl reductase from Candida parapsilosis CCTCC M203011 in Escherichia coli]
    Ying Sun
    Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China
    Wei Sheng Wu Xue Bao 48:1629-33. 2008
    ....
  18. ncbi [Effects of pilocarpine in new ophthalmic formulations on intraocular pressure in rabbits with ocular hypertension]
    Yan Xu
    Henan Institute of Ophthalmology, Zhengzhou 450003, China
    Zhonghua Yan Ke Za Zhi 38:721-4. 2002
    ..To assess the effects of pilocarpine (PC) incorporated into an in situ gelling vehicle, submicron emulsion vehicle, polyvinyl alcohol vehicle and PC solution on intraocular pressure (IOP) in rabbits with carbomer-induced elevation of IOP...
  19. ncbi [Studies of the association between angiotensinogen gene regulation and cytokines in essential hypertension]
    Ai Ling Wang
    First Affiliated Hospital of Anhui Medical University, Hefei 230022, China
    Yi Chuan Xue Bao 30:978-82. 2003
    ..It is also suggested the cytokines may effect the transcription and expression of AGT gene 235 TT genotype in hypertension. The concentrations of IL-1, IL-6 and TNF had nothing to do with age no matter hypertensives or controls...
  20. ncbi [Ocular pharmacokinetics of 0.5% pilocarpine with sodium hyaluronate in rabbits]
    Yan Xu
    Henan Institute of Ophthalmology, Zhengzhou 450003, China
    Zhonghua Yan Ke Za Zhi 40:87-9. 2004
    ..To compare the pharmacokinetics of 0.5% pilocarpine containing sodium hyaluronate with 1% generic pilocarpine solution...
  21. ncbi [The effect of propyl gallate on the activity of various antifungal drugs against filamentous fungi in vitro]
    Yan Xu
    Henan Institute of Ophthalmology, Zhengzhou 450003, China
    Zhonghua Yan Ke Za Zhi 42:309-12. 2006
    ....
  22. ncbi [Loss of heterozygosity at chromosome 8p21-p23 in adenocarcinoma of gastric cardia]
    Xiao Hui Man
    Department of Medical Genomics, MOH Key Laboratory of Cell Biology, China Medical University, Shenyang 110001, China
    Yi Chuan 28:641-5. 2006
    ..6%. One common deleted region of about 1.2 Mb (8p22GGAA-8p22ATCT) was defined. Our data indicated that the tumor suppressor gene at chromosome 8p22 might play an important role in the development of adenocarcinoma of gastric cardia...
  23. ncbi [Effects of periosteum, synovium and cartilage tissues on genes for joint cartilage regeneration]
    Yan Xu
    Department of Orthopedics, Nanjing First Hospital, Nanjing Medical University, Nanjing Jiangsu, 210006, PR China
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 20:670-4. 2006
    ....
  24. ncbi [Mineralization effects of human platelet-rich plasma on human periodontium cells]
    Yan Xu
    Department of Periodontology, School and Hospital of Stomatology, Anhui Medical University, Hefei 230032, China
    Zhonghua Kou Qiang Yi Xue Za Zhi 41:743-6. 2006
    ..To observe the effects of platelet-rich plasma (PRP) on inducing mineralization of human gingival fibroblasts (GF), periodontal ligament cells (PDLC) and alveolar bone osteoblasts (AOB)...
  25. ncbi [Human osteoblasts attachment to guided tissue regeneration membranes which were coated either with platelet-rich plasma or platelet-poor plasma]
    Yan Xu
    Department of Periodontology, School and Hospital of Stomatology, Anhui Medical University, Hefei 230032, China
    Zhonghua Kou Qiang Yi Xue Za Zhi 42:496-500. 2007
    ....
  26. ncbi [Analysis of free terpenoids in four Vitis vinifera varieties using solvent assisted flavour evaporation and gas chromatography-tadem mass spectrometry]
    Wenguang Jiang
    Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China
    Se Pu 25:881-6. 2007
    ..The results showed that this method can be used to identify and quantify the free terpenoids in grapes...
  27. doi In vitro odontoblast-like cell differentiation of cranial neural crest cells induced by fibroblast growth factor 8 and dentin non-collagen proteins
    Hong bing Jiang
    College of Stomatology, Nanjing Medical University, Nanjing, Jiangsu 210029, PR China
    Cell Biol Int 32:671-8. 2008
    ..CNC cells may be used as a valuable cell model for research on dental tissue differentiation and regeneration...
  28. doi Changes in morphology of Rhizopus chinensis in submerged fermentation and their effect on production of mycelium-bound lipase
    Yun Teng
    Laboratory of Brewing Microbiology and Applied Enzymology, School of Biotechnology, Jiangnan University, 1800 Lihu Rd, 214122, Wuxi, Jiangsu, People s Republic of China
    Bioprocess Biosyst Eng 32:397-405. 2009
    ..These results indicate that morphology changes affected the lipase production significantly for R. chinensis and the aggregated mycelia were suggested to achieve high lipase production...
  29. pmc In vitro comparison of the efficacies of natamycin and silver nitrate against ocular fungi
    Yan Xu
    Department of Ocular Pharmacology, Henan Institute of Ophthalmology, Zhengzhou, China
    Antimicrob Agents Chemother 53:1636-8. 2009
    ..and 1 microg/ml for Aspergillus spp. MIC(90)s of natamycin were 8 microg/ml for Fusarium spp. and 32 microg/ml for Aspergillus spp. Silver nitrate exhibited potent antifungal activity against ocular fungi in vitro...
  30. ncbi [A study of experimental carbomer glaucoma and other experimental glaucoma in rabbits]
    Yan Xu
    Henan Institute of Ophthalmology, Zhengzhou 450003, China
    Zhonghua Yan Ke Za Zhi 38:172-5. 2002
    ..To establish models of experimental glaucoma in rabbits to investigate the treatment of glaucoma...
  31. ncbi Modulation of gamma-aminobutyric acid on painful sense in central nervous system of morphine-dependent rats
    Yan Xu
    College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China
    Neurosci Bull 24:278-82. 2008
    ..To observe the effects of gamma-aminobutyric acid (GABA) on the electric activities of pain-excited neurons (PEN) in nucleus accumbens (NAc) in central nervous system (CNS) of morphine-dependent rats...