Yajun Xu

Summary

Country: China

Publications

  1. ncbi request reprint Effect of folic acid on prenatal alcohol-induced modification of brain proteome in mice
    Yajun Xu
    Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100083, China
    Br J Nutr 99:455-61. 2008
  2. ncbi request reprint [Effect of ethanol on the development of mouse neuroblasts]
    Yajun Xu
    Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100083, China
    Wei Sheng Yan Jiu 36:568-71. 2007
  3. doi request reprint Combined developmental toxicity of bisphenol A and genistein in micromass cultures of rat embryonic limb bud and midbrain cells
    Yang Xiao
    Department of Toxicology, School of Public Health, Peking University, Beijing, China
    Toxicol In Vitro 25:153-9. 2011
  4. ncbi request reprint Effects of ginsenoside Rg1 on postimplantation rat and mouse embryos cultured in vitro
    Peng Liu
    School of Public Health, Department of Nutrition and Food Hygiene, Peking University, 38, Xue Yuan Road, Hai Dian District, Beijing 100083, China
    Toxicol In Vitro 20:234-8. 2006
  5. ncbi request reprint Ethanol exposure induces differential microRNA and target gene expression and teratogenic effects which can be suppressed by folic acid supplementation
    Lin Lin Wang
    Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100191, PR China
    Hum Reprod 24:562-79. 2009
  6. ncbi request reprint Effects of folinic acid and Vitamin B12 on ethanol-induced developmental toxicity in mouse
    Yajun Xu
    Department of Nutrition and Food Hygiene, School of Public Health, Laboratory of Molecular Toxicology and Developmental Molecular Biology, Peking University, Beijing 100083, China
    Toxicol Lett 167:167-72. 2006
  7. ncbi request reprint Ercc6l, a gene of SNF2 family, may play a role in the teratogenic action of alcohol
    Yajun Xu
    Laboratory of Molecular Toxicology and Developmental Molecular Biology, Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100083, China
    Toxicol Lett 157:233-9. 2005
  8. ncbi request reprint The maternal combined supplementation of folic acid and Vitamin B(12) suppresses ethanol-induced developmental toxicity in mouse fetuses
    Yajun Xu
    Department of Nutrition and Food Hygiene, Laboratory of Molecular Toxicology and Developmental Molecular Biology, School of Public Health, Peking University, Beijing 100083, China
    Reprod Toxicol 22:56-61. 2006
  9. ncbi request reprint Effect of marine collagen peptides on long bone development in growing rats
    Yajun Xu
    Department of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing, China
    J Sci Food Agric 90:1485-91. 2010
  10. ncbi request reprint Prevention of retinoic acid-induced early craniofacial abnormalities by folinic acid and expression of endothelin-1/dHAND in the branchial arches in mouse
    Zhaofeng Zhang
    Department of Nutrition and Food Hygiene, Laboratory of Molecular Toxicology and Developmental Molecular Biology, School of Public Health, Peking University, Beijing 100083, P R China
    Br J Nutr 96:418-25. 2006

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Effect of folic acid on prenatal alcohol-induced modification of brain proteome in mice
    Yajun Xu
    Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100083, China
    Br J Nutr 99:455-61. 2008
    ....
  2. ncbi request reprint [Effect of ethanol on the development of mouse neuroblasts]
    Yajun Xu
    Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100083, China
    Wei Sheng Yan Jiu 36:568-71. 2007
    ..To investigate the effect of ethanol on the development of embryonic neuroblasts and the relation to ethanol's teratogenicity...
  3. doi request reprint Combined developmental toxicity of bisphenol A and genistein in micromass cultures of rat embryonic limb bud and midbrain cells
    Yang Xiao
    Department of Toxicology, School of Public Health, Peking University, Beijing, China
    Toxicol In Vitro 25:153-9. 2011
    ..While the evidence of GEN as a teratogen was solid, especially with the consideration of "high dose" application in clinical treatment. The combined effect of BPA and GEN was generally additive action except that in MB proliferation...
  4. ncbi request reprint Effects of ginsenoside Rg1 on postimplantation rat and mouse embryos cultured in vitro
    Peng Liu
    School of Public Health, Department of Nutrition and Food Hygiene, Peking University, 38, Xue Yuan Road, Hai Dian District, Beijing 100083, China
    Toxicol In Vitro 20:234-8. 2006
    ..We suggest that pregnant women of first trimester should use ginseng with caution before the exact conclusion is obtained...
  5. ncbi request reprint Ethanol exposure induces differential microRNA and target gene expression and teratogenic effects which can be suppressed by folic acid supplementation
    Lin Lin Wang
    Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100191, PR China
    Hum Reprod 24:562-79. 2009
    ..microRNAs (miRNAs) play an important role in development and are associated with birth defects. Data are scant on the role of miRNAs in birth defects arising from exposure to environmental factors such as alcohol...
  6. ncbi request reprint Effects of folinic acid and Vitamin B12 on ethanol-induced developmental toxicity in mouse
    Yajun Xu
    Department of Nutrition and Food Hygiene, School of Public Health, Laboratory of Molecular Toxicology and Developmental Molecular Biology, Peking University, Beijing 100083, China
    Toxicol Lett 167:167-72. 2006
    ..The present investigation indicated that combined supplementation of folic acid and VB(12) might be a better choice than folic acid alone in the prevention of ethanol-induced birth defects...
  7. ncbi request reprint Ercc6l, a gene of SNF2 family, may play a role in the teratogenic action of alcohol
    Yajun Xu
    Laboratory of Molecular Toxicology and Developmental Molecular Biology, Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100083, China
    Toxicol Lett 157:233-9. 2005
    ..The expressions in the other three organs were unaffected. From the results, we considered that Ercc6l might play a role in the teratogenic action of alcohol...
  8. ncbi request reprint The maternal combined supplementation of folic acid and Vitamin B(12) suppresses ethanol-induced developmental toxicity in mouse fetuses
    Yajun Xu
    Department of Nutrition and Food Hygiene, Laboratory of Molecular Toxicology and Developmental Molecular Biology, School of Public Health, Peking University, Beijing 100083, China
    Reprod Toxicol 22:56-61. 2006
    ..These results suggest that combined supplementation of FA and VB(12) was more effective than each vitamin toward suppressing ethanol-induced developmental toxicity in CD-1 mice...
  9. ncbi request reprint Effect of marine collagen peptides on long bone development in growing rats
    Yajun Xu
    Department of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing, China
    J Sci Food Agric 90:1485-91. 2010
    ..In the present study, the effect of marine collagen peptides (MCP) derived from chum salmon (Oncorhynchus keta) skin on the development of femurs in growing rats of both sexes was investigated...
  10. ncbi request reprint Prevention of retinoic acid-induced early craniofacial abnormalities by folinic acid and expression of endothelin-1/dHAND in the branchial arches in mouse
    Zhaofeng Zhang
    Department of Nutrition and Food Hygiene, Laboratory of Molecular Toxicology and Developmental Molecular Biology, School of Public Health, Peking University, Beijing 100083, P R China
    Br J Nutr 96:418-25. 2006
    ..The present results suggest that folinic acid may prevent retinoic acid-induced craniofacial abnormalities via increasing ET-1 and dHAND levels in the branchial region during the organogenic period...
  11. ncbi request reprint [Effects of vitamin B12 on ethanol-induced mouse embryonic abnormality in vitro]
    Li Li
    School of Public Health, Peking University, Beijing 100083, China
    Wei Sheng Yan Jiu 36:178-81. 2007
    ..To evaluate the developmental improvement of vitamin B12 on ethanol-induced embryonic abnormality in vitro...
  12. doi request reprint Effects of cod bone gelatin on bone metabolism and bone microarchitecture in ovariectomized rats
    XiaoLong Han
    Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China
    Bone 44:942-7. 2009
    ....
  13. doi request reprint Embryotoxic and teratogenic effects of the combination of bisphenol A and genistein on in vitro cultured postimplantation rat embryos
    Lina Xing
    Department of Toxicology, School of Public Health, Peking University, Beijing 100191, People s Republic of China
    Toxicol Sci 115:577-88. 2010
    ..The current findings suggest that pregnant women should not take soy supplements, but more studies are necessary to provide a conclusive recommendation...
  14. ncbi request reprint Effect of ethanol on the development of visceral yolk sac
    Yajun Xu
    Department of Nutrition and Food Hygiene, Laboratory of Molecular Toxicology and Developmental Molecular Biology, School of Public Health, Peking University, Beijing, China
    Hum Reprod 20:2509-16. 2005
    ..Functional suppression of yolk sac is found to be relevant to the malformations in mammalian embryos...
  15. pmc Developmental effects of dietary nucleotides in second-generation weaned rats
    Meihong Xu
    Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China
    J Med Food 16:1146-52. 2013
    ..01% dose. Although NTs may have cumulative reproductive effects, they were safe even at a high-dose supplementation. Additionally, NT supplementation could promote restoration and optimize liver function...
  16. doi request reprint Multigenerations assessment of dietary nucleotides consumption in weaned rats
    Meihong Xu
    Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, People s Republic of China
    Birth Defects Res B Dev Reprod Toxicol 95:460-6. 2012
    ..05) of NTs male, there were no differences between the control and NTs groups in blood indicators. NTs could promote early growth and development of rats after weaning, especially in males...
  17. ncbi request reprint Activation of p38/MEF2C pathway by all-trans retinoic acid in cardiac myoblasts
    Xia Ren
    Laboratory of Development Molecular Biology, Department of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing 100083, PR China
    Life Sci 81:89-96. 2007
    ..These results suggest that atRA may mediate p38/MEF2C signaling pathway during heart development...
  18. ncbi request reprint Developmental toxicity research of ginsenoside Rb1 using a whole mouse embryo culture model
    Peng Liu
    School of Public Health, Peking University, Beijing, China
    Birth Defects Res B Dev Reprod Toxicol 74:207-9. 2005
    ..Ginseng has been widely used around the world for many years. Knowledge is limited, however, on its effects on embryonic development...
  19. ncbi request reprint Impaired development of mitochondria plays a role in the central nervous system defects of fetal alcohol syndrome
    Yajun Xu
    Department of Nutrition and Food Hygiene, School of Public Health, Laboratory of Molecular Toxicology and Developmental Molecular Biology, Peking University, Beijing, China
    Birth Defects Res A Clin Mol Teratol 73:83-91. 2005
    ..Most mechanism studies of alcohol-related CNS defects have been focused on the morphologically abnormal tissues, and more attention has been paid to nuclear alteration as opposed to organelle development...
  20. ncbi request reprint Maternal supplementation of nucleotides improves the behavioral development of prenatal ethanol-exposed mice
    Wenhong Dong
    Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China
    Cogn Affect Behav Neurosci 14:879-90. 2014
    ..However, different sensitivities were found between the two sexes. ..
  21. ncbi request reprint Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis
    Elena S Izmailova
    Millennium Pharmaceuticals, Inc, Cambridge, Massachusetts 02139, USA
    Arthritis Rheum 56:117-28. 2007
    ..To elucidate how IKK-2 inhibition suppresses disease development, we used a combination of in vivo imaging, transcription profiling, and histopathology technologies to study mice with antibody-induced arthritis...