Affiliation: Xi'an Jiaotong University
- β2-adrenoceptor blockage induces G1/S phase arrest and apoptosis in pancreatic cancer cells via Ras/Akt/NFκB pathwayDong Zhang
Department of Hepatobiliary and Pancreas Surgery, First Affiliated Hospital, Xi an Jiaotong University, Xi an 710061, China
Mol Cancer 10:146. 2011..To clarify the mechanism of apoptosis induced by β2-adrenergic antagonist, we hypothesize that blockage of the β2-adrenoceptor could induce G1/S phase arrest and apoptosis and Ras may be a key player in PanCa cells...