Chundong Yu


Affiliation: Xiamen University
Country: China


  1. Peng K, Kou L, Yu L, Bai C, Li M, Mo P, et al. Histone Demethylase JMJD2D Interacts with Beta-catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice. Gastroenterology. 2018;: pubmed publisher
    ..JMJD2D interacts with beta-catenin to activate transcription of its target genes and promote CRC cell proliferation, migration, and invasion as well as formation of colorectal tumors in mice. ..
  2. Tong Z, Li M, Wang W, Mo P, Yu L, Liu K, et al. Steroid Receptor Coactivator 1 Promotes Human Hepatocellular Carcinoma Progression by Enhancing Wnt/β-Catenin Signaling. J Biol Chem. 2015;290:18596-608 pubmed publisher
    ..Our results demonstrate that SRC-1 promotes HCC progression by enhancing Wnt/β-catenin signaling and suggest that SRC-1 is a potential therapeutic molecular target for HCC. ..
  3. Peng K, Su G, Ji J, Yang X, Miao M, Mo P, et al. Histone demethylase JMJD1A promotes colorectal cancer growth and metastasis by enhancing Wnt/?-catenin signaling. J Biol Chem. 2018;293:10606-10619 pubmed publisher
    ..Of note, high JMJD1A levels in CRC specimens predicted poor cancer outcomes. In summary, JMJD1A promotes CRC progression by enhancing Wnt/?-catenin signaling, implicating JMJD1A as a potential molecular target for CRC management. ..
  4. An Y, Wu J, Yang B, Zhu Z, Gao M, Yu C, et al. Selection and Application of DNA Aptamer Against Oncogene Amplified in Breast Cancer 1. J Mol Evol. 2015;81:179-85 pubmed publisher
    ..More importantly, the aptamer was found to disrupt in the interaction between p300 and AIB1. This aptamer has great potential to serve as a therapeutic agent for cancer by inhibiting the coactivation of AIB1. ..
  5. Chen W, Lü X, Chen Y, Li M, Mo P, Tong Z, et al. Steroid Receptor Coactivator 3 Contributes to Host Defense against Enteric Bacteria by Recruiting Neutrophils via Upregulation of CXCL2 Expression. J Immunol. 2017;198:1606-1615 pubmed publisher
    ..Collectively, we show that SRC-3 contributes to host defense against enteric bacteria, at least in part via upregulating CXCL2 expression to recruit neutrophils. ..