Chonggang Wang


Affiliation: Xiamen University
Country: China


  1. Xi Z, Fang L, Xu J, Li B, Zuo Z, Lv L, et al. Exposure to Aroclor 1254 persistently suppresses the functions of pancreatic β-cells and deteriorates glucose homeostasis in male mice. Environ Pollut. 2019;249:822-830 pubmed publisher
    ..However, β-cell mass eventually failed to make sufficient levels of insulin, resulting in significant increases in fasting blood glucose, and indicating the development of T2DM. ..
  2. Gao D, Lin J, Ou K, Chen Y, Li H, Dai Q, et al. Embryonic exposure to benzo(a)pyrene inhibits reproductive capability in adult female zebrafish and correlation with DNA methylation. Environ Pollut. 2018;240:403-411 pubmed publisher
    ..These results suggest that short-term exposure in early life should be included and evaluated in any risk assessment of pollutant exposure to the reproductive health of fish. ..
  3. Wu Y, Zuo Z, Chen M, Zhou Y, Yang Q, Zhuang S, et al. The developmental effects of low-level procymidone towards zebrafish embryos and involved mechanism. Chemosphere. 2018;193:928-935 pubmed publisher
    ..The results of this study will be helpful in evaluating the potential threat of PCM to fish population in the aquatic environment. ..
  4. Sun L, Zuo Z, Chen M, Chen Y, Wang C. Reproductive and transgenerational toxicities of phenanthrene on female marine medaka (Oryzias melastigma). Aquat Toxicol. 2015;162:109-16 pubmed publisher
    ..In addition, PHE can be maternally transferred to embryos and influence the health and sustainability of the next generation. ..
  5. Huang L, Zuo Z, Zhang Y, Wang C. Toxicogenomic analysis in the combined effect of tributyltin and benzo[a]pyrene on the development of zebrafish embryos. Aquat Toxicol. 2015;158:157-64 pubmed publisher
    ..These results suggested that toxicogenomic approach was available for analyzing combined toxicity with high sensitivity and accuracy, which might improve our understanding and predictability for the combined effects of chemicals. ..
  6. Wu Y, Yang Q, Chen M, Zhang Y, Zuo Z, Wang C. Fenbuconazole exposure impacts the development of zebrafish embryos. Ecotoxicol Environ Saf. 2018;158:293-299 pubmed publisher
    ..These results suggest that FBZ could have toxic effects on embryonic development, which should be considered in the risk evaluation of FBZ application. ..
  7. Dong X, Zhang L, Chen M, Yang Z, Zuo Z, Wang C. Exposure to difenoconazole inhibits reproductive ability in male marine medaka (Oryzias melastigma). J Environ Sci (China). 2018;63:126-132 pubmed publisher
    ..The decrease of the fertilization success, the hatch ability and the swim-up success in the F1 generation indicated that DFZ pollution at environmental levels might cause a decrease of wild fish populations. ..
  8. Huang L, Zuo Z, Zhang Y, Wu M, Lin J, Wang C. Use of toxicogenomics to predict the potential toxic effect of Benzo(a)pyrene on zebrafish embryos: ocular developmental toxicity. Chemosphere. 2014;108:55-61 pubmed publisher
    ..Our results were helpful for an understanding of the toxicity of BaP. This study also indicated that microarray analysis was effective for predicting the potential toxicity of chemicals with high sensitivity and accuracy. ..
  9. Li B, Guo J, Xi Z, Xu J, Zuo Z, Wang C. Tributyltin in male mice disrupts glucose homeostasis as well as recovery after exposure: mechanism analysis. Arch Toxicol. 2017;91:3261-3269 pubmed publisher
    ..However, the fasting levels of serum adiponectin and glucagon were lower than that of the control mice, which would remain a potential risk inducing the disruption of glucose homeostasis. ..

More Information


  1. Dong X, Zuo Z, Guo J, Li H, Zhang L, Chen M, et al. Reproductive effects of life-cycle exposure to difenoconazole on female marine medaka (Oryzias melastigma). Ecotoxicology. 2017;26:772-781 pubmed publisher
    ..Thus, a more extensive evaluation of the impact of DFZ on marine fish reproduction at realistic environmental concentrations is needed. ..