Research Topics
Genomes and GenesSpecies | Bing XiaSummaryCountry: China Publications
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Publications
The prevalence and risk factors of cytomegalovirus infection in inflammatory bowel disease in Wuhan, Central ChinaFengming Yi
Department of Gastroenterology, Zhongnan Hospital of Wuhan University School of Medicine, Donghu Road 169, Wuhan 430071, PR of China
Virol J 10:43. 2013..The etiologic link between IBD and CMV infection needs to be studied. The objective of the present study is to investigate the prevalence and risk factors of CMV in a cohort of IBD patients from Central China...
MICB0106 gene polymorphism is associated with ulcerative colitis in central ChinaYi Li
Department of Gastroenterology and Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University School of Medicine, Wuhan, People s Republic of China
Int J Colorectal Dis 25:153-9. 2010..MICA and MICB gene polymorphisms and expressions are associated with autoimmune diseases but not known in ulcerative colitis (UC)...
Methionine synthase A2756G polymorphism may predict ulcerative colitis and methylenetetrahydrofolate reductase C677T pancolitis, in Central ChinaMin Chen
INSERM, U724, Laboratory of Cellular and Molecular Pathology in Nutrition, Faculty of Medicine, Nancy Universite, Nancy Vandoeuvre, France
BMC Med Genet 9:78. 2008..We evaluated the association of the polymorphisms of MTHFR, MTR, MTRR and TCN2 genes with ulcerative colitis in Central China...
Association of diminished expression of RASSF1A with promoter methylation in primary gastric cancer from patients of central ChinaMei Ye
Department of Internal Medicine and Geriatrics, Research Centre of Digestive Diseases, Zhongnan Hospital, Wuhan University, PR China
BMC Cancer 7:120. 2007....
Cytotoxic T lymphocyte antigen-4 promoter -658CT gene polymorphism is associated with ulcerative colitis in Chinese patientsYan Luo
Key Laboratory of Allergy and Immune Related Diseases, School of Medicine, Wuhan University, Wuhan, Hubei Province, People s Republic of China
Int J Colorectal Dis 24:489-93. 2009..The present study aimed to examine an association between the CTLA-4 gene polymorphisms and ulcerative colitis (UC) in the Han Chinese in central China...
[Association of cytotoxic T lymphocyte antigen-4 promoter C-658T polymorphism with ulcerative colitis in Chinese]Yan Luo
Department of Gastroenterology, Zhongnan Hospital, Wuhan University School of Medicine, Wuhan, Hubei, 430071 P R China
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 26:431-4. 2009..To investigate the association of gene polymorphism of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) with ulcerative colitis (UC) in Chinese...
Association between interleukin-1 gene polymorphisms and Helicobacter pylori infection in gastric carcinogenesis in a Chinese populationChun Li
Department of Internal Medicine and Geriatrics, Zhongnan Hospital, Wuhan University School of Medicine, Wuhan, China
J Gastroenterol Hepatol 22:234-9. 2007..pylori-induced gastric inflammation. The present study aimed to determine polymorphisms of IL-1B and IL-1 receptor antagonist (IL-1RN) genes and their association with H. pylori infection and gastroduodenal diseases in Chinese patients...
The prevalence and diagnostic value of perinuclear antineutrophil cytoplasmic antibodies and anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease in mainland ChinaFeng Zhou
Department of Gastroenterology, Zhongnan Hospital, Wuhan University School of Medicine, Wuhan 430071, People s Republic of China
Clin Chim Acta 411:1461-5. 2010..We determined the prevalence of pANCA and ASCA in the mainland Chinese population and the ability of pANCA and ASCA to discriminate between ulcerative colitis (UC) and Crohn's disease (CD)...
Distribution of peroxisome proliferator-activated receptor-gamma polymorphisms in Chinese and Dutch patients with inflammatory bowel diseaseUmid Kumar Shrestha
Department of Gastroenterology, Wuhan University, Zhongnan Hospital, Wuhan, People s Republic of China
Inflamm Bowel Dis 16:312-9. 2010..The aims of the present study were to determine the distribution of PPAR-gamma polymorphisms Pro12Ala and C161T and to explore the association between the PPAR-gamma genotypes and phenotypes of IBD patients...
Distribution of signal transducer and activator of transcription 6 gene G2964A polymorphism in Chinese patients with ulcerative colitisJianbo Zhu
Department of Internal Medicine and Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan, China
J Gastroenterol Hepatol 21:1854-7. 2006..The aim of the present study was to determine distribution of the STAT6 gene polymorphism in Chinese patients with ulcerative colitis...
[Association of IL-10 gene polymorphisms with gastroduodenal diseases in Hubei Han population]Hui Xiao
Department of Hematology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, 430071 P R China
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 26:423-6. 2009..To study the distribution of IL-10 gene polymorphisms in patients with gastroduodenal diseases in Hubei Han population and their association with helicobacter pylori (Hp) infection...
Upregulated mRNA expression of major histocompatibility complex class I chain-related gene A in colon and activated natural killer cells of Chinese patients with ulcerative colitisLiu Qing Ge
Department of Gastroenterology and Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University, Wuhan, Hubei Province, China
J Dig Dis 12:82-9. 2011....
Risk factors for ulcerative colitis in a Chinese population: an age-matched and sex-matched case-control studyLi Jiang
Department of Internal Medicine and Geriatrics of Zhongnan Hospital, Wuhan University School of Medicine, Wuhan, PR China
J Clin Gastroenterol 41:280-4. 2007..We conducted a case-control study to examine associations between previously reported environmental risk factors and development of ulcerative colitis (UC) in Wuhan city, central China...
Sinomenine attenuates 2, 4, 6-trinitrobenzene sulfonic acid-induced colitis in miceHong Cheng
Department of Internal Medicine and Geriatrics, Zhongnan Hospital, Research Center of Digestive Diseases, Wuhan University School of Medicine, Wuhan 430071, PR China
Int Immunopharmacol 7:604-11. 2007..Our findings suggest that sinomenine attenuates TNBS-induced colitis in mice and the therapeutic mechanism might be related to the reduction of up-regulated colonic TNF-alpha and IFN-gamma production caused by TNBS...
[The relationship between major histocompatibility complex class I chain-related antigens A (MICA)-129 gene polymorphism, soluble MICA level and ulcerative colitis]Jie Zhao
Department of Gastroenterology, Wuhan University Zhongnan Hospital, Wuhan 430071, China
Zhonghua Nei Ke Za Zhi 50:311-5. 2011..To investigate the association of the major histocompatibility complex class I chain-related antigens A (MICA)-129 gene polymorphism and soluble MICA (sMICA) levels with ulcerative colitis (UC) in Hubei Han nationality...
Association of CTLA-4 gene microsatellite polymorphism with ulcerative colitis in Chinese patientsYi Jiang
Department of Internal Medicine and Geriatrics, Research Center of Digestive Diseases, Zhongnan Hospital, Key Laboratory of Allergy and Immune Related Diseases, Wuhan University School of Medicine, Wuhan, China
Inflamm Bowel Dis 12:369-73. 2006..The longer alleles of the CTLA-4 gene microsatellite polymorphism were strongly associated with UC in Chinese patients...
Meta-analysis: total parenteral nutrition versus total enteral nutrition in predicted severe acute pancreatitisFengming Yi
Department of Gastroenterology, Zhongnan Hospital of Wuhan University School of Medicine, China
Intern Med 51:523-30. 2012..In addition, enteral nutrition treatment methods have developed; early enteral nutrition has already been highlighted for severe acute pancreatitis, but the therapeutic risks versus benefits need to be studied...
Prevalence and risk factors of fatty liver disease in the Shuiguohu district of Wuhan city, central ChinaZhongli Wang
Department of Internal Medicine and Geriatrics, Wuhan University School of Medicine, Zhongnan Hospital, Wuhan, PR China
Postgrad Med J 83:192-5. 2007..Fatty liver disease (FLD) is highly prevalent in Western countries, but recent data have shown that FLD is also emerging in China...
[The relationship of methylenetetrahydrofolate reductase G1793A gene polymorphism, hyperhomocysteinaemia and ulcerative colitis]Yi Jiang
Department of Gastroenterology, Wuhan University Zhongnan Hospital, Wuhan 430071, China
Zhonghua Nei Ke Za Zhi 49:675-9. 2010....
Epigenetic regulation of death-associated protein kinase expression in primary gastric cancers from Chinese patientsMei Ye
Department of Gastroenterology, Hubei Clinical Centre and Key Laboratory of Intestinal and Colorectal Diseases, Zhongnan Hospital of Wuhan University School of Medicine, Wuhan, Hubei Province, People s Republic of China
Eur J Cancer Prev 21:241-6. 2012..04). DAPK protein and mRNA expression was reduced in GC tissues of Chinese patients. Diminished expression of DAPK was associated with promoter methylation...
CD4⁺T cells: differentiation and functionsRishi Vishal Luckheeram
Department of Gastroenterology, Zhongnan Hospital, Wuhan University School of Medicine, Wuhan 430071, China
Clin Dev Immunol 2012:925135. 2012..This paper will focus on the cytokine-signaling and the network of transcription factors responsible for the differentiation of naive CD4⁺T cells...
Type IVB pilus operon promoter controlling expression of the severe acute respiratory syndrome-associated coronavirus nucleocapsid gene in Salmonella enterica Serovar Typhi elicits full immune response by intranasal vaccinationFengling Luo
Department of Immunology, Hubei Province Key Laboratory of Allergy and Immune related Diseases, The State Key Laboratory of Virology, Wuhan University School of Medicine, Wuhan 430071, People s Republic of China
Clin Vaccine Immunol 14:990-7. 2007..Our work also indicates that the type IVB pilus operon promoter controlling foreign gene expression in Salmonella can elicit full immune responses by intranasal vaccination...
Defects of FA/BRCA pathway in lymphoma cell linesHui Xiao
Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People s Republic of China
Int J Hematol 88:543-50. 2008..In conclusion, this mutation maybe the reason which caused FANCN protein expression absent or made the protein very unstable and lose its function in HT and JEKO-1 cell lines...
